• 대한의생명과학회지
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• 제18권4호
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• pp.384-390
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• 2012

Diabetes mellitus (DM) is considered to be a serious metabolic disease which may cause systemic complications. The present study was designed to clarify a difference on stress, physiological variables and their correlation between diabetic (DM group) and nondiabetic adults (control group). The levels of body weight, waist circumference, blood pressure, body mass index, body fat mass, total cholesterol (TcH), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyltransferase (GGT), total bilirubin (TB), autonomic balance (AB), stress index (SI), fatigue index (FI), and heart rate (HR) were all significantly higher in the DM group than in the control group. However, the levels of autonomic activity (AA), stress resistance (SR), and electrocardiac stability (ES) were significantly lower in the DM group than in the control group. The percentages of persons with abnormal levels in the Tch, high density lipoprotein, low density lipoprotein, TG, AST, ALT and GGT were significantly greater in the DM group than in the control group. In the correlation of glucose and hemoglobin A1c (HBA1c) to stress indices, the DM group had a significant relationship with AB, SR, SI, FI, ES, and HR, whereas the control group had no significant relationship with these, excepting AB. These results suggest that DM was harmfully associated with body, biochemical and stress indices and that blood glucose and HBA1c levels must be exhaustively regulated.

• 동아시아식생활학회지
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• 제4권2호
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• pp.17-26
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• 1994

This study was an attempt to investigate various factions, such as the calorie, nutrient intake, physical activity, blood lipids, obesity prevalence and body fat distribution on NIDDM male diabetics. General characteristics, physical activity and exercise levels of subjects were invesigated by interviewing, daily calorie and nutrient intake were measured by convenient method. The following anthropometric measurements were made on all participats : weight, height. Also waist and hip circumference were measured on 174 male diabetics to get waist-to-hip circumference ratio as index of the body fat distribution. For measurement of plasma lipids, 12-hour fasting blood samples were drawn The results of this study were summarized as follows : 1. At the onset of diabetes, the major self-diagnosed symptoms were polydipsia, fatigue, and body weight redution 2. The average of daily energy intake of male diabetics was 2106 Kcal which is 96% of the RDA Percentage of energy is that carbohydrate:protein : pat=70:14:16. 3. Among the NIDDM male subjects, 59% was exercise regularly. 4. Obese subjects above in the ideal body weight of 120% are presently 17%, but 39% of subjects were reported to be obese in the past. The mean BMI of the male NIDDM diabetics is 23.3${\pm}$2.6 and the past mean BMI was 25.2${\pm}$2.7 The mean WHR was 0.93${\pm}$0.10. 5. When diabetics were divided into obese and nonobese group according to RBW, energy intake, blood pressure, blood glucose and total cholesterol were not significantly different between the two groups, but LDL and VLDL-cholesterol were significantly higher in the obese group. 6. RBW did not correlate with cholesterol and triglyceride, but WHR correlated significantly with cholesterol and triglyceride. In conclusion, these results from a present study support previous findings indicating that not only the degree of obesity but also the localization of fat is a risk factor for diabetes.

• 사상체질의학회지
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• 제30권3호
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• pp.48-61
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• 2018

Objectives The purpose of this study was to investigate the ordinary symptoms, special symptoms and Body Mass Index (BMI) according to Sasang constitution in female college students. Also, we aimed to analyze the factors affecting BMI. Methods Forty-four female college students participated in this study. Sasang Constitution was determined by Questionnaire for Sasang Constitution Classification (QSCC) II. BMI was measured and ordinary symptoms were acqired through the questionnaire. Special symptoms was determined by Fatigue Severity Index (FSS), Premenstrual Symptom Screening Tool (PSST), ROME III, Ocular Surface Disease Index (OSDI), respectively. For statistical analysis, t-test, analysis of variance and correlation test has been used. Results There existed significant differences in ordinary symptoms and special symptoms between sasang constitutions. Taeumin had higher urine frequency than soyangin, soeumin had higher gap of feces than taeumin. Taeumin had higher BMI and ROME III score than soyangin and soeumin. They showed significant differences in ordinary symptoms and special symptoms according to BMI. Overweight and obese group is higher in water intake than low and normal group. Low weight and normal group is higher in gap of feces than overweight and obese group. High score group in PSST and ROME III showed high BMI than low score group. We analyzed the factors that affect BMI. BMI are highly correlated with systolic and diastolic blood pressure. Also, FSS, PSST, ROME III and OSDI showed high correlation with each other. Conclusion Urine frequency and gap of feces are different among sasang constitutional types. The obese group and normal group showed significant differences in water intake, gap of feces, PSST and ROME III score. It is found that factors that affecting BMI are systolic and diastolic blood pressure. These results may lead to identifying the causes and factors of obesity in female college students related to Sasang constitution.

• 생명과학회지
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• 제20권6호
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• pp.870-876
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• 2010

본 연구의 목적은 kinesio taping 적용이 근력 향상에 미치는 영향을 직 간접적으로 관찰함으로써 운동 수행시의 상해예방 및 수행력 향상을 위한 수단으로서의 taping 요법에 대한 기초 자료를 제공하는데 있었다. 본 연구는 남자 대학생 10명을 대상으로, 근력 향상의 정도를 직접적으로 관찰하기 위하여 1RM test와 Cybex test를 실시하였으며, 생리학적 변인으로는 CK, LDH, phosphorus, ammonia, creatinine, IGF-I의 6가지 혈중 성분을 분석함으로써 피로와 근 손상의 정도를 분석하였다. 본 연구를 통하여 kinesio taping은 근력향상의 직접적인 지표(1RM, 등속성 운동능력)에는 긍정적으로 작용했지만, 85%-1RM의 웨이트트레이닝 시의 근 피로 또는 근 손상 지표물질의 농도는 유의하게 감소시키지 못함을 알 수 있었다. 하지만 본 연구의 결과만을 가지고 taping의 적용이 피로 및 근 손상 완화 효과가 없다고 판단할 수는 없을 것으로 생각된다. 왜냐하면, 본 연구에서의 피로 및 근 손상 유발 수단인 85%-1RM 웨이트트레이닝은 고강도의 운동이며 운동에 소요된 시간도 40분 정도로 장시간이지만 다양한 근육부위에 적은 반복수와 set를 적용하였기 때문에 피로 및 근 손상 지표물질의 축적이 현저하지 않았을 수 있기 때문이다. 이는 taping 적용 후 나타난 여러 혈중성분들의 감소(Creatinine 제외) 경향으로 설명할 수 있으며, 실제로 선행 연구 중 특정 대근육에 대한 반복적인 운동에 kinesio taping을 적용하여 피로 및 근 손상 완화를 입증하기도 하였다. 본 연구가 가지는 의의는 특정 동작에 있어서의 근력 향상을 중점적으로 관찰한 연구가 아닌, 전신에 대한 taping을 적용한 후 각 근육 부위에 어떠한 영향을 미치는지 다양한 관점에서 관찰하였다는 데 있다. 이후의 연구에서는 본 연구에서 관찰한 변인들 이외에도 신경계통의 변인들과의 상관관계도 함께 관찰 하는 통합적인 연구도 의의가 있다고 하겠다.

• Nutritional Sciences
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• 제8권3호
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• pp.189-195
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• 2005

To assess the effect of pinitol supplementation and strength training for two weeks on the anaerobic capacity during and after exercise, and improvement of glucose metabolism during the recovery period of muscular fatigue with repeated acute bouts of cycling exercise, a total of 24 healthy young men were recruited and randomly and equally divided into three groups; pinitol supplementation group (PSG), placebo group (PLG), and control group (CON). Using a randomized double-blinded design, subjects in PSG were provided pinitol supplement, consumed orally 1.2 g/day, and participated in the resistance exercise program and cycling exercise for two weeks. Subjects in PLG underwent the same protocol as those in PSG but consumed the same amount of placebo. No supplementation and exercise program was given to CON. Before and after the intervention, all subjects were tested for their anaerobic capacities evaluated by Wingate test twice separated by 30 min. During the test, peak anaerobic power (PP), mean anaerobic power, total work, and fatigue index were evaluated During resting and recovery, blood samples were drawn and plasma pinitol, myo-inositol, chiro-inositol, insulin, free fatty acid, glucose, and lactate levels were analyzed After two weeks, PP and relative PP of the second biking were improved from the first biking in PSG only (p<0.05). No changes were found in all other variables of Wingate test in all groups. No statistical differences between groups and pre- and post-intervention were observed in concentrations of pinitol, myo-inositol, and chiro-inositol, but pinitol concentration was higher during recovery compared to the baseline in all groups and testings (p<0.05). Lactate level during recovery was higher than the resting level, but no other blood parameters were significantly changed. In conclusion, two weeks of pinitol supplementation in conjunction with short duration of anaerobic training in healthy young men did not induce any obvious benefits in terms of anaerobic capacity and energy metabolism Individual and/or population susceptibility may be one factor responsible for adopting pinitol supplementation.

• 사상체질의학회지
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• 제34권2호
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• pp.75-83
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• 2022

Objectives The aim of this study is to report the improvement in Taeeumin's dryness-heat symptom of a 54-year-old man diagnosed with type-II diabetes mellitus after treated by herbal medicine. Methods The Taeeumin patient took Yuldahansotang-gamibang for 9 months to manage Taeeumin's dryness-heat symptom. We examined the changes of Body Mass Index(BMI), Fating Blood Sugar(FBS), Hemoglobin A1c(HbA1c), and ketouria. Results Type-II diabetes mellitus symptoms in the patient with Taeeumin's dryness-heat symptom were thirst, fatigue, and increased body weight. All numerical levels for blood sugar, HbA1c, and ketouria were reduced after taking Yuldahansotang-gamibang. Conclusions The treatment of the patient with Taeeumin's dryness-heat symptom and type-II diabetes mellitus with Yuldahansotang-gamibang was efficient, and further research is needed to prove the effect of Yuldahansotang-gamibang for treating such patients.

• 대한한의학회지
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• 제21권3호
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• pp.213-219
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• 2000

We treated a 53 year-old male patient. He had alcoholic liver cirrhosis and diabetes. The main symptoms were fatigue, ascites, edema, anorexia, indigestion, constipation, and abdominal pain. We diagnosed him as 'the retention of pathogenic damp-heat in the liver and gall bladder’ and adminstered Saenggangeonbi-tang three times a day. We observed clinical symptoms, liver function test(AST, ALT, ${\gamma}-GT$, ALP, total bilirubin), nutritional state(total protein, albumin) and capillary blood glucose. After treatment, all the main symptoms disappeared and the patient's nutritional state has improved. Child's grade using the improvement index in liver cirrhosis has changed from B to A. Although the very mechanism of Saenggangeonbi-tang was not proven, we could suggest that Saenggangeonbi-tang is not toxic to the liver and has a good effect on alcoholic liver cirrhosis with diabetes mellitus.

• 동의생리병리학회지
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• 제33권4호
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• pp.239-248
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• 2019

There are no published data on Gyeongokgo (GOK) safety or efficacy despite being commonly use. The Gyeongokgo (GOK) is commonly used in traditional Korean medicine to promote a health qi and blood, but their objective data was not sufficient in clinical field. To investigate the safety and efficacy of GOK with hematologic and serologic testing and the change of the quality of life in healthy individuals. Randomized, subject-assessor-blind, placebo-controlled, single-center pilot study Participants and Interventions 29 healthy volunteer subjects were randomly placed into the GOK group (n = 20) or placebo control group (n = 9) and instructed to take one treatment packet (GOK or placebo) twice daily for 4 weeks. Subjects were assessed using the Fatigue Severity Scale (FSS) and Short Form 36 Health Survey (SF-36) and underwent hematologic and serologic tests and body composition analysis. The FSS total score (p = 0.093) and SF-36 general health index (p = 0.002) were improved following treatment in the GOK group. Post-treatment thyroid-stimulating hormone levels were increased in the GOK group compared with pre-treatment levels (p = 0.0042). C-reactive protein levels decreased (p = 0.0256) in the GOK group compared with that the placebo group. In time-series tests, GOK did not affect post-prandial serum triglycerides, glucose, insulin, or C-peptide levels. Notably, elevations in serum fasting triglycerides at 2- (p = 0.0333) and 4-hours (p = 0.0414) post-prandial were lower than those in the placebo group. GOK reduced fatigue levels and did not significantly affect laboratory test results performed to measure safety, serum glucose, and lipid profiles. Post-meal triglyceride levels were effectively reduced with treatment.

• 한국응용과학기술학회지
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• 제37권6호
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• pp.1646-1658
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• 2020

이 연구의 목적은 운동 후 수중회복방법의 차이가 성장호르몬, 테스토스테론, 혈중젖산농도, 심부담도, 통증의 변화를 알아보는 것이다. 저항운동 경력 6개월 이상인 남자 7명을 대상으로 집중 웨이트 트레이닝과 서킷 웨이트트레이닝을 1RM의 60%강도로 실시한 다음 회복방법으로 수중걷기회복과 수중앉기 회복을 진행하였다. 성장호르몬은 모든 운동형태와 회복방법에서 운동 후, 회복 후, 안정 시 순으로 높게 나타났으며, 테스토스테론은 운동 후, 회복 후, 안정 시 순으로 높았다. 혈중젖산농도는 모든 운동형태와 회복방법에서 운동 후, 회복 후, 안정 시 순으로 높았으며 집중저항운동 후 동적회복이 정적회복보다 낮았다. 심부담도는 모든 운동형태와 회복방법에서 운동 후, 회복 후, 안정 시 순으로 높았다. 근통증은 모든 운동형태와 회복방법에서 운동직후, 회복 후, 24시간, 48시간, 72시간 순으로 감소하였다. 물속 환경에서도 동적회복이 정적회복보다 근피로 개선에 효과가 있는 것으로 사료된다.

• 대한한방부인과학회지
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• 제19권4호
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• pp.225-244
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• 2006

Purpose : This study was performed to assess the clinical effect of Daejo-hwan(DJH) on climacteric syndrome, not only common symptoms such as hot flushes, anxiety, palpitation and so on, but also urogenital tract disturbances like vaginal dryness and sexual problems. Methods : We randomly divided 120 women with the climacteric syndrome into two groups. One group received only DJH 2 pills(4g) a time, three times a day for 8 weeks and the other group didn't get any treatment for the same period. We evaluated sonography, DXA, blood test, female hormone test and questionnaires in the beginning as well as after 8 weeks of the treatment. Symptoms were measured by Kupperman's index, Menopausal Rating Scale and the Greene Climacteric Scale. Results : In this study, DJH was innoxious on liver and kidney. And DJH in the treated group reduced climacteric symptoms significantly as compared to the control group without enlargement of uterus myoma and the change of estradiol. In Kupperman's index and MRS, DJH in the treated group especially had effects on fatigue, shoulder pain. anxiety, headache, hot flushes as well as sexual problems. Conclusion : These results suggest that DJH can be useful in treating various climacteric symptoms including sexual problems without influences on the size of uterus myoma and estradiol.