• BMB Reports
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• v.56 no.1
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• pp.43-48
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• 2023

Pre-clinical models are critical in gaining mechanistic and biological insights into disease progression. Recently, patient-derived organoid models have been developed to facilitate our understanding of disease development and to improve the discovery of therapeutic options by faithfully recapitulating in vivo tissues or organs. As technological developments of organoid models are rapidly growing, computational methods are gaining attention in organoid researchers to improve the ability to systematically analyze experimental results. In this review, we summarize the recent advances in organoid models to recapitulate human diseases and computational advancements to analyze experimental results from organoids.

• Molecules and Cells
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• v.27 no.3
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• pp.321-327
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• 2009

Voltage-dependent anion channels (VDACs) are reported to be porin-type, ${\beta}$-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol. In this study, we have investigated a family of VDAC isoforms in Arabidopsis thaliana (AtVDAC). We have shown that the heterologous expression of AtVDAC proteins can functionally complement a yeast mutant lacking the endogenous mitochondrial VDAC gene. AtVDACs tagged with GFP were localized to mitochondria in both yeast and plant cells. We also looked at the response of AtVDACs to biotic and abiotic stresses and found that four AtVDAC transcripts were rapidly up-regulated in response to a bacterial pathogen.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2003.04a
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• pp.105-105
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• 2003

• Journal of Fisheries and Marine Sciences Education
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• v.29 no.3
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• pp.719-731
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• 2017

The aim of this study was to analyze a group of pre-service elementary teachers experience on the cognitive terms of biology inquiry subjects, and experience on living materials related with the domain of life in the Korea elementary school science textbook. Firstly, elementary school pre-service teachers had the confidence of inquiry subjects related with the domain of life such as 'when we take breath what will happen in human body?' and 'Can we make the model of human body?' But they did have the most diffidence of 'The search for pieris rapae, a cabbage butterfly's life', 'Can we grow the little creature?' The reason why pre-service elementary teachers had diffidence of comprehending experiment procedure and planning ability was that 'they focused on understanding the scientific concepts instead of planning experiments by themselves', and 'they carried out the least amount of experiments' Secondly, elementary school pre-service teachers had never experienced biology materials related with the domain of life in the Korea elementary school biology science textbook such as 'tradescantia reflexa', 'Caddis larva', 'hydrilla verticillata', and 'Plantain lily.' According to the findings obtained from the study, the reason why they had never seen the biology materials was that they had the least opportunity of immediately observing life creatures due to memorization-intensive classes.

• Proceedings of the Zoological Society Korea Conference
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• 2000.10a
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• pp.137.2-138
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• 2000

No Abstract, See Full Text

• Proceedings of the Zoological Society Korea Conference
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• 1997.10b
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• pp.263.2-263
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• 1997

No Abstract, See Full Text

• Proceedings of the Korean Society of Life Science Conference
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• 2005.09a
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• pp.106-106
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• 2005

• Korean Journal of Agricultural Science
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• v.46 no.1
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• pp.79-84
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• 2019

The family Lyctocoridae was taxonomically reviewed on the Korean peninsula with the finding of a new record, Lyctocoris ichikawai Yamada & Yasunaga, 2012. Morphological information such as a description of genitalia and a diagnosis as well as a key to the Korean species of the family is provided.

• Molecules and Cells
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• v.38 no.8
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• pp.685-696
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• 2015

Rice is a model plant widely used for basic and applied research programs. Plant cell wall proteins play key roles in a broad range of biological processes. However, presently, knowledge on the rice cell wall proteome is rudimentary in nature. In the present study, the tightly-bound cell wall proteome of rice callus cultured cells using sequential extraction protocols was developed using mass spectrometry and bioinformatics methods, leading to the identification of 1568 candidate proteins. Based on bioinformatics analyses, 389 classical rice cell wall proteins, possessing a signal peptide, and 334 putative non-classical cell wall proteins, lacking a signal peptide, were identified. By combining previously established rice cell wall protein databases with current data for the classical rice cell wall proteins, a comprehensive rice cell wall proteome, comprised of 496 proteins, was constructed. A comparative analysis of the rice and Arabidopsis cell wall proteomes revealed a high level of homology, suggesting a predominant conservation between monocot and eudicot cell wall proteins. This study importantly increased information on cell wall proteins, which serves for future functional analyses of these identified rice cell wall proteins.

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2005.11a
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• pp.48-48
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• 2005