• 센서학회지
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• 제17권1호
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• pp.29-34
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• 2008

A new disposable amperometric tri-enzyme biosensor for the detection of paracetamol has been developed. The paracetamol sensors developed uses horseradish peroxidase modified screen-printed carbon electrodes (HRP-SPCEs) coupled with immobilized enzymes, tyrosinase and aryl acylamidase, prepared using a poly (vinyl alcohol) bearing styrylpyridinium groups (PVA-SbQ) matrix. Optimization of the experimental parameters has been performed and the paracetamol biosensor showed detection limit for paracetamol is as low as $100{\mu}M$ and the sensitivity of the sensor is $1.46nA{\mu}M^{-1}cm^{-2}$.

• 센서학회지
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• 제15권2호
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• pp.77-83
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• 2006

A monitoring apparatus for pulse shapes of human heartbeats has been developed using an amorphous MI(Magnetic Impedance) sensor. The pulse shapes are successfully obtained from voltage signals due to the variations of magnetic impedance in the amorphous MI sensor, which is attached to a patient's wrist. This voltage signal was fed into a signal processing module to extract the pulse shapes of heartbeats. The signal processing module, which is proposed to detect a weak variations of impedance in MI sensor under a noisy measurement environment, consists of a high frequency current source, an amplifier stage and a synchronous detection circuit. To evaluate the characteristics of a newly developed apparatus, various experiments were performed. The experimental results show that the developed apparatus could be used as a diagnosis tool for traditional Korean medicine with further systematic clinical studies.

• Journal of the Optical Society of Korea
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• 제17권5호
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• pp.423-427
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• 2013

We present the preparation and characteristics of liquid-phase sensors based on nano-porous silicon multilayer structures for determination of organic content in gasoline. The principle of the sensor is a determination of the cavity-resonant wavelength shift caused by refractive index change of the nano-porous silicon multilayer cavity due to the interaction with liquids. We use the transfer matrix method (TMM) for the design and prediction of characteristics of microcavity sensors based on nano-porous silicon multilayer structures. The preparation process of the nano-porous silicon microcavity is based on electrochemical etching of single-crystal silicon substrates, which can exactly control the porosity and thickness of the porous silicon layers. The basic characteristics of sensors obtained by experimental measurements of the different liquids with known refractive indices are in good agreement with simulation calculations. The reversibility of liquid-phase sensors is confirmed by fast complete evaporation of organic solvents using a low vacuum pump. The nano-porous silicon microcavity sensors can be used to determine different kinds of organic fuel mixtures such as bio-fuel (E5), A92 added ethanol and methanol of different concentrations up to 15%.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2008년도 추계종합학술대회 B
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• pp.340-347
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• 2008

오늘날 가정은 더 이상 의식주를 해결하는 곳이 아니다. 이제 홈 네트워크는 예전 말이 되었고 가정 내 디지털 가전기기들은 OSGi 나 UPnP등이 확장되어 언제 어디서나 인터넷을 통해 자동 제어되고 있다. 본 연구는 OSGi나 UPnP 확장을 통해 디지털 홈 네트워크 미들웨어를 기본 제공하고 JESS 추론 엔진을 통해 스마트 홈 네트워크를 구성한다. 그리고 휴대용 심전도, 혈압, 맥박, 체온 등의 생체 신호 측정 센서를 통하여 생체 인식 기반 스마트 홈 미들웨어를 제공하여, 사용자가 집에서 머무르는 동안 사용자와 근접하여 사용자가 요구하는 홈 서비스를 예측하여 자동으로 제공해 주며, 제공된 홈 서비스가 사용자에게 미치는 스트레스를 분석하여 사용자가 가장 편안하게 느끼는 홈 서비스를 추천하고 사용자의 건강 상태를 실시간으로 모니터링하여 사용자의 건강 상태가 나빠지면 자동으로 사용자, 가족 그리고 의사에게 자동으로 알려주는 시스템을 구축한다.

• 한국통신학회논문지
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• 제38C권7호
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• pp.573-586
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• 2013

다양한 IT융합기술 분야 중 바이오 및 환경센서를 활용한 농축산 산업분야에 관한 연구가 최근 주목받고 있다. 그중 축산산업의 질적 향상을 위한 방법으로 IT기술융합이 절실히 요구되고 있다. 특히, 축산물에 대한 실시간 건강산태 모니터링, 질병발생시 원인 파악 및 즉각적인 향후 대처방안 수립 등이 이에 해당된다. 이에 본 논문에서는 무선 센서 네트워크 기반에서의 축산산업 분야에서 축사 환경 모니터링 및 환경개선 시스템을 제안한다. 제안된 시스템은 축사의 무선 환경정보 수집 노드, 환경개선 노드, 축사 게이트웨이, 서버로 구성되어 대규모 축산산업 환경 모니터링과 환경개선이 가능하여 상황에 따른 능동적인 대응 및 가축의 최적 생활 요건과 질병발생시 환경에 따른 정보의 실시간 수집 및 최적 환경제어가 가능하다. 제안된 시스템을 활용하면, 집단 폐사와 같은 재해에 실시간 대응 및 가축관리의 최적 생활요건을 제공함으로써 축산 산업분야의 IT 융합기술의 성공적인 적용이 가능하다고 판단된다.

• 센서학회지
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• 제30권3호
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• pp.170-174
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• 2021

As the rising attention to the medical and healthcare issue, Bio-MEMS (Micro electro mechanical systems) platform such as bio sensor, cell culture system, and microfluidics device has been studied extensively. Bio-MEMS platform mostly has high resolution structure made by biocompatible material such as polydimethylsiloxane (PDMS). In addition, three dimension structure has been applied to the bio-MEMS. Lithography can be used to fabricate complex structure by multiple process, however, non-rectangular cross section can be implemented by introducing optical apparatus to lithography technic. X-ray lithography can be used even for sub-micron scale. Here in, we demonstrated lines with round shape cross section using the tilted gold absorber which was deposited on the oblique structure as the X-ray mask. This structure was used as a mold for PDMS. Molded PDMS was applied to the cell culture platform. Moreover, molded PDMS was bonded to flat PDMS to utilize to the sub-micro channel. This work has potential to the large area bio-MEMS.

• 센서학회지
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• 제15권3호
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• pp.158-163
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• 2006

This paper reports a novel immunoassay method using superparamagnetic nanoparticles and an enhanced magnetic field gradient for the detection of protein in a microfluidic device. We use superparamagnetic nanoparticles as a label and fluorescent polystyrene beads as a solid support. Based on this platform, magnetic force-based microfluidic immunoassay is successfully applied to analyze the concentration of IgG as model analytes. In addition, we present ferromagnetic microstructure connected with a permanent magnet to increase magnetic flux density gradient (dB/dx, ${\sim}10^{4}$ T/m), which makes limit of detection reduced. The detection limit is reduced to about 1 pg/mL.

• Journal of Magnetics
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• 제11권4호
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• pp.189-194
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• 2006

The recent development of bio-conjugated magnetic nanoparticles offers many opportunities for applications in the field of biomedicine. In particular, the use of magnetic nanoparticles for biosensing has generated widespread research efforts following the progress of various magnetic field sensors. Here we demonstrate substrate-free biosensing approaches based on the Brownian rotation of ferromagnetic nanoparticles suspended in liquids. The signal transduction is through the measurement of the magnetic ac susceptibility as a function of frequency, whose peak position changes due to the modification of the hydrodynamic radius of bio-conjugated magnetic nanoparticles upon binding to target bio-molecules. The advantage of this approach includes its relative simplicity and integrity compared to methods that use substrate-based stray-field detectors.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회A
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• pp.1767-1772
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• 2008

A microcantilever is a well-known MEMS structure for sensing bio-chemical molecules. When bio-chemical molecules are adsorbed on the microcantilever's surface, resonance frequency shift is generated. There are two issues in this phenomena. The first one is which one between mass change and surface stress change effects is more dominant on the resonance frequency shift. The second one is what will be the performance change when the boundary condition is changed from cantilevers to double clamped beams. We have studied the effect of surface stress change and compared it with that of mass change by using FEM analysis. Furthermore, for microstructures having different boundary conditions, we have studied Q-factor, which determines the detection limit of micro/nano mechanical sensors.

• 센서학회지
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• 제25권3호
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• pp.223-228
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• 2016

In this work, we prepared porous WO3 nanofibers (NFs) functionalized by bio-inspired catalytic $Cr_2O_3$ and $Co_3O_4$ nanoparticles as highly sensitive and selective $H_2S$ gas sensing layers. Highly porous 3-dimensional (3D) NFs networks decorated by well-dispersed catalyst NPs exhibited superior $H_2S$ gas response ($R_{air}/R_{gas}$ = 46 at 5 ppm) in high humidity environment (95 %RH). In particular, the sensors showed outstanding $H_2S$ selectivity against other interfering analytes (such as acetone, toluene, CO, $H_2$, ethanol). Exhaled breath sensors using $Cr_2O_3$ and $Co_3O_4$ catalysts-loaded $WO_3$ NFs are highly promising for the accurate detection of halitosis.