Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Tri-enzyme modified electrochemical biosensor for paracetamol detection

파라세타몰 검출을 위한 전기화학적 다중효소 바이오센서

  • Park, Deog-Su (Center for Innovative Bio. Physio Sensor Technology, Pusan National University) ;
  • Shim, Yoon-Bo (Department of Chemistry, Pusan National University) ;
  • Chang, Seung-Cheol (Center for Innovative Bio. Physio Sensor Technology, Pusan National University)
  • 박덕수 (부산대학교 신개념바이오.피지오센서기술연구센터) ;
  • 심윤보 (부산대학교 화학과) ;
  • 장승철 (부산대학교 신개념바이오.피지오센서기술연구센터)
  • Published : 2008.01.31
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Abstract

A new disposable amperometric tri-enzyme biosensor for the detection of paracetamol has been developed. The paracetamol sensors developed uses horseradish peroxidase modified screen-printed carbon electrodes (HRP-SPCEs) coupled with immobilized enzymes, tyrosinase and aryl acylamidase, prepared using a poly (vinyl alcohol) bearing styrylpyridinium groups (PVA-SbQ) matrix. Optimization of the experimental parameters has been performed and the paracetamol biosensor showed detection limit for paracetamol is as low as $100{\mu}M$ and the sensitivity of the sensor is $1.46nA{\mu}M^{-1}cm^{-2}$.

Keywords

References

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