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Pelvic, Hip, and Knee Kinematics of Stair Climbing in People with Genu Varum

  • Chae, Yun Won;Park, Seol;Park, Ji Won
    • The Journal of Korean Physical Therapy
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    • v.30 no.1
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    • pp.14-22
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    • 2018
  • Purpose: This study examined the effects of the lower limb alignment on the pelvis, hip, and knee kinematics in people with genu varum during stair walking. Methods: Forty subjects were enrolled in this study. People who had intercondylar distance ${\geq}4cm$ were classified in the genu varum group, and people who had intercondylar distance <4cm and intermalleolar distance <4cm were placed in the control group. 3D motion analysis was used to collect the pelvis, hip, and knee kinematic data while subjects were walking stairs with three steps. Results: During stair ascent, the genu varum group had decreased pelvic lateral tilt and hip adduction at the early stance phase and decreased pelvic lateral tilt at the swing phase compared to the control group. At the same time, they had decreased minimal hip adduction ROM at the early stance and decreased maximum pelvic lateral tilt ROM and minimum hip rotation ROM at the swing phase. During stair descent, the genu varum group had decreased pelvic lateral tilt at the early stance and decreased pelvic lateral tilt and pelvic rotation at the swing phase. In addition, they had decreased pelvic frontal ROM during single limb support and increased knee sagittal ROM during the whole gait cycle. Conclusion: This study suggests that a genu varum deformity could affect the pelvis, hip and knee kinematics. In addition, the biomechanical risk factors that could result in the articular impairments by the excessive loads from lower limb malalignment were identified.

Optimization of Growth Medium and Fermentation Conditions for the Production of Laccase3 from Cryphonectria parasitica Using Recombinant Saccharomyces cerevisiae

  • Jeong, Yong-Seob;Sob, Kum-Kang;Lee, Ju-Hee;Kim, Jung-Mi;Chun, Gie-Taek;Chun, Jeesun;Kim, Dae-Hyuk
    • Mycobiology
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    • v.47 no.4
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    • pp.512-520
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    • 2019
  • Statistical experimental methods were used to optimize the medium for mass production of a novel laccase3 (Lac3) by recombinant Saccharomyces cerevisiae TYEGLAC3-1. The basic medium was composed of glucose, casamino acids, yeast nitrogen base without amino acids (YNB w/o AA), tryptophan, and adenine. A one-factor-at-a-time approach followed by the fractional factorial design identified galactose, glutamic acid, and ammonium sulfate, as significant carbon, nitrogen, and mineral sources, respectively. The steepest ascent method and response surface methodology (RSM) determined that the optimal medium was (g/L): galactose, 19.16; glutamic acid, 5.0; and YNB w/o AA, 10.46. In this medium, the Lac3 activity (277.04 mU/mL) was 13.5 times higher than that of the basic medium (20.50 mU/mL). The effect of temperature, pH, agitation (rpm), and aeration (vvm) was further examined in a batch fermenter. The best Lac3 activity was 1176.04 mU/mL at 25 ℃, pH 3.5, 100 rpm, and 1 vvm in batch culture.

Assessment of geothermal potential in an area of sulfate-rich hot springs, Bugok, southern Korea

  • Park Seong-Sook;Yun Seong-Taek;Chae Gi-Tak;So Chil-Sup;Koh Yong-Kwon;Choi Hyeon-Su
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2006.04a
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    • pp.303-306
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    • 2006
  • Using a variety of chemical geothermometers we estimate the temperature of a deep geothermal reservoir in relation to thermal groundwater in the Bugok area, southern Korea, in order to assess the potential use of geothermal energy in South Korea. Thermal water at Bugok has been exploited down to about 400 m below the land surface and shows the highest outflow temperatures (up to $78{\circ}C$) in South Korea. Based on the hydrochemical data and occurrence, groundwater in Bugok can be classified into three groups: $Na-SO_4$ type thermal groundwater (CTGW) occurring in the central part (about 0.24 $km^2$) $Ca-HCO_3$ type cold groundwater (SCGW) occurring in shallow peripheral parts of CTGW; and the intermediate type groundwater (STGW). CTGW waters are typical of thermal water in the area, because they have the highest outflow temperatures and contain very high concentrations of Na, K and $SiO_2$ due to the sufficient reaction with silicate minerals in deep reservoir. Their enriched $SO_4$ was likely formed by gypsum dissolution. The major ion composition of CTGW shows the general approach to a partial equilibrium state with rocks at depth. The application of various alkali ion geothermometers yields temperature estimates in the range of 88 to $198{\circ}C$ for the thermal reservoir. Multiple mineral equilibrium calculation indicates asimilar but narrower temperature range between about 100 and $155{\circ}C$. These temperature estimates are not significantly higher than the measured outflow temperatures for CTGW Considering the heat loss during the ascent- of thermal waters, this fact may suggest that a thermal reservoir in the study area is likely located at relatively shallow depths (possibly close to the depth of preexisting wells). Therefore, we suggest a high potential for geothermal energy development around the Bugok area in southern Korea.

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Improving Evaluation of the Basket-to-Handstand Mount by a Technical Training Program on Parallel Bars (평행봉 Basket to Handstand 기술 훈련 프로그램 적용을 통한 향상도 평가)

  • Lee, Chong-Hoon;Back, Jin-Ho
    • Korean Journal of Applied Biomechanics
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    • v.19 no.4
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    • pp.719-728
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    • 2009
  • In this study, a training program was conducted to improve the performance of the basic movement of the basket-to-handstand mount. After completion of the training program, the kinematic comparison of the before and after effects were investigated to provide scientific data about this technique. It is recommended that during P1, the center of body mass at the back should push the hip joint to flex quickly, and the shoulder joint should be maintained at a maximum angle. During P2, the body's center of mass must be accelerated so as to create enough momentum to rise efficiently for this, quick extension of both the hip and the shoulder is required. For safety during P3, it is advised that the speed upwards must be increased and that the hands, shoulders, and hip joint must be extended, as in the posture of a handstand. These results stress to coaches the importance of the bodies speed during the ascent in the motion.

Vision-based Autonomous Landing System of an Unmanned Aerial Vehicle on a Moving Vehicle (무인 항공기의 이동체 상부로의 영상 기반 자동 착륙 시스템)

  • Jung, Sungwook;Koo, Jungmo;Jung, Kwangyik;Kim, Hyungjin;Myung, Hyun
    • The Journal of Korea Robotics Society
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    • v.11 no.4
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    • pp.262-269
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    • 2016
  • Flight of an autonomous unmanned aerial vehicle (UAV) generally consists of four steps; take-off, ascent, descent, and finally landing. Among them, autonomous landing is a challenging task due to high risks and reliability problem. In case the landing site where the UAV is supposed to land is moving or oscillating, the situation becomes more unpredictable and it is far more difficult than landing on a stationary site. For these reasons, the accurate and precise control is required for an autonomous landing system of a UAV on top of a moving vehicle which is rolling or oscillating while moving. In this paper, a vision-only based landing algorithm using dynamic gimbal control is proposed. The conventional camera systems which are applied to the previous studies are fixed as downward facing or forward facing. The main disadvantage of these system is a narrow field of view (FOV). By controlling the gimbal to track the target dynamically, this problem can be ameliorated. Furthermore, the system helps the UAV follow the target faster than using only a fixed camera. With the artificial tag on a landing pad, the relative position and orientation of the UAV are acquired, and those estimated poses are used for gimbal control and UAV control for safe and stable landing on a moving vehicle. The outdoor experimental results show that this vision-based algorithm performs fairly well and can be applied to real situations.

Mechanical System Design and Development of the HAUSAT-1 Picosatellite (초소형위성 HAUSAT-1의 기계시스템 설계 및 개발)

  • Hwang, Ki-Lyong;Min, Myung-Il;Moon, Byoung-Young;Chang, Young-Keun
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.32 no.9
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    • pp.103-113
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    • 2004
  • The satellite is exposed to the severe vibration environments such as random vibration environments such as random vibration, acceleration, shock, and acoustics during launch ascent and transportation. It is also faced with various space environments such as thermal vacuum, radiation and microgravity during the mission life. The satellite should be designed, manufactured, assembled and tested to be able to endure in these harsh environments. This paper addresses the results of the structural and thermal design and analyses for the HAUSAT-1 picosatellite which is scheduled to launch in the first quarter of 2005 by Russian launch vehicle "Dnepr". The qualification vibration and thermal vacuum tests have been conducted and passed at the satellite level to ensure that the HAUSAT-1 mechanical system was designed to be stable with enough margin.

Study on the "Moschus substitute for Aquilariae Resinatum Lignum or Aucklandiae Radix" of Gongjin-Dan In The Classic Literature. (拱辰丹의 "麝香 代入 沈香 或 木香"에 관한 古典文獻 硏究)

  • Lee, Min-Seok;Lee, Jong-Hoon;Yoon, Tae-Kwan;Lee, Jang-Cheon;Lee, Boo-Kyun
    • Herbal Formula Science
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    • v.23 no.2
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    • pp.235-243
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    • 2015
  • Objectives : The object of this paper is to seek and provide evidences for the possibilities of substitutional use of Aquilariae Resinatum Lignum and Aucklandiae Radix for Moschus as an ingredient of Gongjin-dan by clarifying the similarities and differences among these herbs in the classic literatures. Methods : We have found out the features of Moschus, Aquilariae Resinatum Lignum and Aucklandiae Radix by searching Qi, Flavor and Effect of each herb in 『Shennongbencaojing』, 『Zhengleibencao』, 『Bencaogangmu』, 『Dongeuibogam』, 『Bencaobeiyao』, 『Euijongsonik』 and 『Bangyakhappyeon』. And we have compared and analyzed the fomula of Gongjin-dan and other prescriptions in 『Beijiqianjinyaofang』, 『Shengjizonglu』, 『Shiyidexiaofang』, 『Dongeuibogam』, 『Euijongsonik』, 『Euibanghwaltu』 and 『Bangyakhappyeon』. Results : We could find out the similarities and differences in Qi, Flavor and Effect among Moschus, Aquilariae Resinatum Lignum and Aucklandiae Radix. And we could also find the examples of substitutional use of Aquilariae Resinatum Lignum as an ingredient of Gongjin-dan by comparing the formula of Gongjin-dan in the classic literatures as above. And in the other prescription, Aucklandiae Radix was also used instead of Moschus. Conclusions : All of three herbs have pungent in Flavor and warm in Qi. And these herbs also have similar effects in dispersing invading pathogenic factors and smoothening the flow of Qi. And according to 『Bencaobeiyao』, 『Euijongsonik』 and 『Bangyakhappyeon』, Aquilariae Resinatum Lignum and Aucklandiae Radix direct and regulate the Qi in common. The substitutional use of Aquilariae Resinatum Lignum and Aucklandiae Radix instead of Moschus in Gonjin-dan seems to be related to 'the ascent of Water and descent of Fire' effect of Gongjin-dan.

Effects of Sucrose, Phosphate, and Calcium Carbonate on the Production of Pikromycin from Streptomyces venezuelae

  • Yi, Jeong Sang;Kim, Minsuk;Kim, Sung-Jin;Kim, Byung-Gee
    • Journal of Microbiology and Biotechnology
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    • v.25 no.4
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    • pp.496-502
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    • 2015
  • Polyketide secondary metabolites share common precursor pools, acyl-CoA. Thus, the effects of engineering strategies for heterologous and native secondary metabolite production are often determined by the measurement of pikromycin in Streptomyces venezuelae. It is hard to compare the effectiveness of engineering targets among published data owing to the different pikromycin production media used from one study to the other. To determine the most important nutritional factor and establish optimal culture conditions, medium optimization of pikromycin from Streptomyces venezuelae ATCC 15439 was studied with a statistical method, Plackett-Burman design. Nine variables (glucose, sucrose, peptone, (NH4)2SO4, K2HPO4, KH2PO4, NaCl, MgSO4·7H2O, and CaCO3) were analyzed for their effects on a response, pikromycin. Glucose, K2HPO4, and CaCO3 were determined to be the most significant factors. The path of the steepest ascent and response surface methodology about the three selected components were performed to study interactions among the three factors, and the fine-tune concentrations for maximized product yields. The significant variables and optimal concentrations were 139 g/1 sucrose, 5.29 g/l K2HPO4, and 0.081 g/l CaCO3, with the maximal pikromycin yield of 35.5 mg/l. Increases of the antibiotics production by 1.45-fold, 1.3-fold, and 1.98-fold, compared with unoptimized medium and two other pikromycin production media SCM and SGGP, respectively, were achieved.

Literatural Study on Physiological Function of Nose (비(鼻)의 생리기능(生理機能)에 대한 연구(硏究))

  • Heo, Jun-Young;Kang, Jung-Soo
    • Journal of Haehwa Medicine
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    • v.9 no.1
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    • pp.121-134
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    • 2000
  • The following results obtained through studies related on nose. 1. Nose is called mingtang(明堂) mianwang(面王), as it emphasize the meaning of viewing diagnosis(望診) and is called yuanpinzhimen(元牝之門), tianpinzhimen(天牝之門), qiqizhimen(七氣之門) as it emphasize the meaning of the entrance of atmosphere flow. Because it's position is the middle of face, we call tianzhongzhiyue(天中之嶽), zhongyue(中嶽). 2. As the organ of body, nose comes under the category of lung-iron(肺金), functionally comes under the category of heart-fire(心火). Functionally we can smell oder, organically nose is the pathway of respiration and to be resonator. 3. Wuzangliufu(五臟六腑) is arranged closely around the nose. The essence of wuzangliufu(五臟六腑) reflect nose, so nose becomes the standard of coloring diagnosis(色診). 4. We call nose is feihou(肺候), but it is not connected directly between the lung channel and nose. In case of lung symptom(肺證), first of all, nose become to appear the condition of lung, the lung channel and nose is close functionally. 5. The view of channels, nose is a connection with channels of yangming(陽明), bladder(膀胱), du(督脈) directly. By the connecting of each three channels, spleen stomach heart and kidney(脾胃心腎) are connected with indirectly. As the result of the relation, nose helps for body to breathe and to circulate qi(氣) and smell. And so the nature of wuzangliufu(五臟六腑) appear to the nose. 6. Particularly, the yangming channel(陽明經), and the bladder channel(膀胱經) are important. Because air-qi(天氣) reach to kidney lung through nose, ground-qi(地氣) reach to spleen stomach through mouth and yingwei(營衛) revolve through the bladder channel(膀胱經). As the result nose becomes the essential organ of circulation of yinewei(營衛), ascent and descent of qi(氣).

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The scope and the task of ontology: Quine's ontological commitment (존재론의 범위와 책무: 콰인의 존재론적 개입)

  • Park, Joonho
    • Korean Journal of Logic
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    • v.16 no.2
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    • pp.233-271
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    • 2013
  • Quinean "ontology" mislead us because it has been used ambiguously even in his single article. It can mean what there is, ie. ontological states of affairs, on what there is, ie. a study of them, or on on what there is, ie. meta-ontology. So it is natural to be confused when we try to fully understand what does Quine do by talking about ontological commitment and criterion of it. We will discriminate these ontologies, and clarity the scope and the task of ontology as a discipline. Ontology is on what there is, meta-ontology is a study on ontology. Ontological commitment is a kind of ontological assertion within ontology, the criterion of ontological commitment is located in meta-ontological level. As a result of this clarification, we can remove some obstacles to get a good grip on Quinean criterion of ontological commitment. Also, we are able to recognize ontological descent, the way by which Quinean substantive ontology proceed.

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