• KSBB Journal
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• v.19 no.6 s.89
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• pp.415-420
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• 2004

All around the world, the rate of attack of cancer diseases has been going up and the number of cancer patients has been increasing every year. Cancer can be divided into malignant tumor and benign tumor according to its growth appearance. Many studies and experiments have been conducted and the various treatment are being created to find the way to care malignant. Dendritic cells (DCs), which is an agent of cancer treatments by using an immune reaction in our body, plays an important role to present by a tumor antigen to cytotoxic T-cell and help them to attack the tumor cell directly. However there are some defects of this therapy. Soluble human leukocyte antigen-immunoglobulin fusion protein (HLA-Ig) based artificial antigen presenting cell (aAPC) as the antigen presenting cell (APC) which is complement and overcome some of the limitations of dendritic cell-based vaccines and ex vivo expansion of human T cells is new method for cancer therapy. In this article, we are reviewing the role of DCs and the treatment with it, and searching for the possibility of the new development of immunotherapy for cancer.

• Journal of the Institute of Convergence Signal Processing
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• v.3 no.4
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• pp.35-41
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• 2002

To solve the large scale optimization problem approximately, various approaches have been introduced. They are mainly based on recent research advancement of simulations for evolutions, flocking, annealing, and interactions among organisms on artificial environments. The typical ones are simulated annealing(SA), artificial neural network(ANN), genetic algorithms(GA), tabu search(TS), etc. Recently the particle swarm optimization(PSO) has been introduced. The PSO simulates the process of birds flocking or fish schooling for food, as with the information of each agent Is share by other agents. The PSO technique has been applied to various optimization problems of which variables are continuous. However, there are seldom trials for visualization of searching process. This paper proposes a new visualization tool for searching process particle swarm optimization(PSO) algorithm. The proposed tool is effective for understanding the searching process of PSO method and educational for students.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.32 no.6
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• pp.497-503
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• 2010

Purpose: The purpose of this study is to induce artificial arthritis on rabbit TMJ by injecting collagenase. Materials and Methods: An experimental animal model of arthritis induced by surgical method or intraarticular injection of chemical agent like LDH, papain, ketorolac. Surgical method is complex and needs a long time in inducing arthritis. Intra-articular injection of chemical agent like LDH, papain, ketorolac is simple. But chemical agent like LDH, papain, ketololac needs multiple injections to induce arthritis and mechanism inducing arthritis was known. Collagenase destroys helical domain of type II collagen in extracellular matrix produced by chondrocyte and then induces arthritis. We injected collagenase (0.5, 1.0, 2.0 mg) into the temporomandibular joint of rabbit. In the control group saline was intra-articularly injected. The condylar cartilage, disk and synovia were histologically examined at 1, 2, 4, 6 weeks after the initiation of collagenase injections. Results: Four weeks after injection of 2.0 mg collagenase, we could see histologic change like arthritis. In other groups, we couldn't see arthritis-like change. Conclusion: In our study, we produce arthritis on temporomandibular joint of rabbit by using injection of collagenase in temporomandibular joint of rabbit. And this experimental osteoarthritis is a useful animal model.

• The Journal of Society for e-Business Studies
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• v.9 no.3
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• pp.155-167
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• 2004

At this time, the two main techniques for achieving web personalization assistant systems generally concern direct manipulation and software agents. While both direct manipulation and software agents are intended for permitting user to complete tasks rapidly, efficiently, and easily, their methodologies are different. The central debate involving these web personalization techniques originates from the amount of control that each allows to, or holds back from, the users. Direct manipulation can provide users with comprehensibel, predictable and controllable user interfaces that give them a feeling of accomplishnent and responsibility. On the other hand, the intelligent software components, the agents, can assist users with artificial intelligence by monitoring or retrieving personal histories or behaviors. In this empirical study, two web personalization assistant systems are evaluated. One of them, WebPersonalizer, is an agent based user personalization tool; the other, AntWorld, is a collaborative recommendation tool which provides direct manipulation interfaces. Through this empirical study, we have focused on two different paradigms as web personalization assistant systems : direct manipulation and software agents. Each approach has its own advantages and disadvantages. We also provide the experimental result that is worth referring for developers of electronic commerce system and suggest the methodologies for conveniently retrieving necessary information based on their personal needs.

• Journal of the korean academy of Pediatric Dentistry
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• v.34 no.2
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• pp.204-214
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• 2007

The aim of this study was to investigate whether differences in surface treatment prior to repair influenced the seal of a resin fissure sealant placed on the occlusal surfaces of permanent molar teeth. One hundred and twenty extracted human molars were selected and a light curing sealant was placed on their occlusal surface following cleaning by prophylaxis and acid etching. The teeth were deliberately damaged, and then stored in artificial saliva for four weeks. Sixty teeth with the desired morphology of sealant failure were randomly divided into four groups where one group was treated with only etching agent, another by only air-abrasion, another by applying an etching agent followed by a bonding agent, and the last by air-abrasion followed by a bonding agent each. After sealant application, the samples were thermocycled and the degree of microleakage was determined. The results were as follows : 1. In the sealant/sealant interface group 2(0.22), 4(0.23) using air-abrasion showed a significantly lower microleakage score than group 1(0.38), 3(0.35) using an etching agent(p<0.05). There were no statistically significant differences(p>0.05) between groups 1, 2 and groups 3, 4. 2. In the sealant/tooth interface, group 3(0.20), 4(0.20) which used a bonding agent showed a significantly lower microleakage score than group 1(0.35), 2(0.40) (p<0.05). There were no statistically significant differences(p>0.05) between groups 1, 3 and groups 2, 4. 3. In SEM examination, while sealant surfaces treated with etching did not result in highly rough surfaces, those treated with air-abrasion did show rough surfaces.

• Journal of the Korea Concrete Institute
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• v.21 no.2
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• pp.147-152
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• 2009

The compressive strength test, bulk density and mortar absorption ratio were carried out to utilize the data as the basic sources for the lightweight mortar and the lightweight concrete, through the study on the physical characteristics of the artificial lightweight aggregate (ALA) made of waste glasses, which was developed for the first time in the country. On the basis of these experiments, the density and the unit volume weight of the ALA showed the value less than 50% of the common aggregate due to the independent pore structure, and the mortar that contains ALA had no big difference from the Control mortar in the test of the absorption ratio. It is judged that this happens based on the internal independent pore structure of the ALA. In case of the mortar containing ALA, there was a tendency of declination in the compressive strength and the bending strength as the mixing rate is increasing, but all mortar showed more than 70% of the Control mortar compressive strength except for the La50 mortar. Hereafter, it is judged that according to the control of the mixing ratio of mineral admixing agent, water and cement, it will realize the equal strength to the control mortar, and the long term edurance is needed to be considered together.

• Resources Recycling
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• v.13 no.3
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• pp.3-11
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• 2004

Basic studies have been conducted regarding the crystal formation of hydroxyapatite which was produced in the treatment process of phosphate-containing wastewater using calcium ions as the precipitating agent for its employment as the material for artificial bones. The precipitation of hydroxyapatite were conducted in the synthetic solution which simulating human body fluid for its increased applicability. Ca($NO_3$)$_2$$.$$4H_2$O and ($NH_4$)$_2$$HPO_4$ were employed for the precipitation of hydroxyapatite and its composition was analyzed after drying at 80oC. The thermal behavior of precipitate was investigated by examining the change in its crystalline structure according to the sintering temperature. DTA/TG analysis showed that the escape of moisture from the precipitate occurred at ca. $100^{\circ}C$ and the decomposition of ammonia and the evaporation of lattice water were brought about at around $250^{\circ}C$. X-ray diffraction analysis indicated that the thermally treated precipitate consisted mainly of hydroxyapatite. For dried precipitate, the bonds in the component materials which used for the precipitate formation were observed by FT-IR, and after thermal treatment the major bonds in the precipitate were shown to be $OH^{-}$, $PO_4^{3-}$ , and $CO_3^{ 2-}$ , which were main comprising bonds of hydroxyapatite.

• Journal of Korean society of Dental Hygiene
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• v.12 no.2
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• pp.335-343
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• 2012

Objectives : The aim of this investigation was to evaluate the remineralization effect of Bamboo salt and NaF+Bamboo salt solutions on bovine enamel formed incipient artificial enamel caries by microcomputed tomography (micro CT). Methods : Experimental solutions were distilled water(negative control), 2% sodium fluoride solution (2% NaF group), 3% bamboo salt solution (3% BS group) and the solution mixed 2% sodium fluoride solution and 3% bamboo salt solution (2% NaF+3% BS group). Specimens were prepared from extracted bovine teeth and divided into 4 groups of 10 specimens each by randomized blocks according to density. Then the specimens surface were divided equally into three parts to observe sound enamel area, incipient enamel carious area and remineralized enamel area. Only one-third of specimen surface was coated with nail varnish and these were exposed to a lactate carbopol buffer system for 72 hours. Then one-half of the demineralized enamel area was coated with nail varnish. The specimens were carried out under pH cycling model for 14 days as follows; samples were immersed in each experimental solution for 2 mins 3 times per day, demineralized for 4 hours and in mixed saliva for the remaining hours. After pH cycling, density was measured using micro CT. Results : All experimental groups showed remineralization effects except for negative control group(p<0.05). The differences of density after experimental solution treatment were statistically significant difference among 4 groups (p<0.01). The density difference values of groups were $0.04{\pm}0.01$ in negative control group, $0.19{\pm}0.01$ in 2% NaF group, $0.14{\pm}0.01$ in 3% BS group, and $0.21{\pm}0.01$ in 2% NaF+3% BS group. Conclusions : The bamboo salt solution showed remineralization effects on incipient artificial enamel caries and the solution mixed sodium fluoride solution and bamboo salt solution showed more remineralization effects than the bamboo salt solution. Thus, it is suggested that bamboo salt can be used as remineralization agent in incipient enamel caries lesion.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.2033-2038
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• 2003

This paper describes an integrated navigation strategy for the autonomous service robot PSR. The PSR is under development at the KIST for service tasks in indoor public environments. The PSR is a multi-functional mobile-manipulator typed agent, which works in daily life. Major advantages of proposed navigation are as follows: 1) Structured control architecture for a systematic integration of various software modules. A Petri net based configuration design enables stable control flow of a robot. 2) A range sensor based generalized scheme of navigation. Any range sensor can be selectively applied using the proposed navigation scheme. 3) No need for modification of environments. (No use of artificial landmarks.) 4) Hybrid approaches combining reactive behavior as well as deliberative planner, and local grid maps as well as global topological maps. A presented experimental result shows that the proposed navigation scheme is useful for mobile service robot in practical applications.

• Journal of the Korea Institute of Building Construction
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• v.11 no.3
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• pp.238-246
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• 2011

Choosing the best-performance materials is a crucial task for the successful completion of a project in the construction field. In general, the process of material selection is performed through the use of information by a highly experienced expert and the purchasing agent, without the assistance of logical decision-making techniques. For this reason, the construction field has considered various artificial intelligence (AI) techniques to support decision systems as their own selection method. This study proposes the application of a systematic and efficient support vector machine (SVM) model to select optimal exterior materials. The dataset of the study is 120 completed construction projects in South Korea. A total of 8 input determinants were identified and verified from the literature review and interviews with experts. Using data classification and normalization, these 120 sets were divided into 3 groups, and then 5 binary classification models were constructed in a one-against-all (OAA) multi classification method. The SVM model, based on the kernel radical basis function, yielded a prediction accuracy rate of 87.5%. This study indicates that the SVM model appears to be feasible as a decision support system for selecting an optimal construction method.