• 제목/요약/키워드: Aristolochia manshuriensis

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등칡의 2기목부요소의 발생학적 변이 (Development Changes of the Secondary Xylem Elements in Aristolochia manshuriensis Komarov)

    • 한국자원식물학회지
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    • 제11권3호
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    • pp.319-325
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    • 1998
  • The developmental changes occuring in the secondary xylem of Aristolochia manshuriensis Komarov have been studied in different ages of vine stems. A. manshuriensis possesses typical storeyed cambium comprising both vertically elongated fusiform initials and almost isodiametric ray cell initials. Stems of A. manshuriensis have wide rays that make the secondary xylem appear dissected as other vine types. The length of vessel member and fiber remained relatively constant throughout the secondary growth. However, vessel diameter increases with the increasing age of stem till the cell reaches their maximum limit and later more or less stabilize in diameter while number of vessel per $\textrm{mm}^2$ is vice versa. Width and relative proportion of ray to axial elements gradually increased with the increasing age of stem and later remained relatively constant.

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한국산(韓國産) Aristolochia속(屬) 식물의 성분 연구(I) (Studies on the Components of the Genus Aristolochia Plants in Korea(I))

  • 정보섭
    • 생약학회지
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    • 제5권3호
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    • pp.167-172
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    • 1974
  • The stems of Aristolochia manshuriensis $K_{OMAROV}$ collected in Kang-won-do, Korea, have been shown to contain aristolochic acids I and II and debilic acid. ${\beta}-Sitosterol$ and the ester of linolic acid were isolated from the petroleum ether: ether(1 : 1) extracts of the stem by using column chromatography.

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'Chinese Herb Nephropathy'란 용어는 올바른 것인가? (Is the term of Chinese Herb Nephropathy proper?)

  • 최기림;이진신;장원만;안영민;안세영;두호경;이병철
    • 대한한방내과학회지
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    • 제21권4호
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    • pp.543-548
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    • 2000
  • After Vanherweghem J-L reported the rapidly progressive interstitial renal fibrosis that developed in patients taking the slimming preparation compounded with chinese Herb in Belgium 1993. Chinese Herb Nephropathy(CHN) has become known as a new renal disease, CHN is described as the decrease of urinary renal enzyme, neutral endopeptidase(NEP). N-acetyl-${\beta}$-Dglucosaminidase(NAG). increase of urinary low molecular protein, ${\alpha}$1-microglobulin, ${\beta}$2-microglobulin. clara cell protein(CC16), retinol-binding protein(RBP) in clinical findings, and the proximal tubular atrophy, interstitial fibrosis. urothelial atrophy. glomerular sclerosis in histology, Because CHN was caused by Chinese herb contained in slimming preparation, western medical doctors have thought that all Herb medicine might have caused renal disease and prohibit the taking of any Herb medicine, However. CHN was actually caused by the aristolochic acid contained in some Herb medicines. Aristolochia manshuriensis, Aristolochia fang chi, which is the substitutions of Akebia quinata, Stephania tetrandra has being used in clinical. Aristolochia manshuriensis. Aristolochia fang chi were different with Akebia quinata. Stephania tetrandra in botany, and it have not been classified with medicines in Oriental medicine, That is, the aristolochic acid, not Herb medicines. causes CHN, So, Chinese Herb Nephropathy should be changed to Aristolochic acid Nephropathy.

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목통(木通).천목통(川木通).관목통(關木通)의 감별기준(鑑別基準) (Criteria for Identifying Akebiae, Clematidis, Aristolochiae Caulis)

  • 이금산;박경범;김영식;이승호;오현민;백지성;조수인;김홍준;주영승
    • 대한본초학회지
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    • 제26권1호
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    • pp.1-6
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    • 2011
  • Objectives : Due to morphological similarity, many substitutes and counterfeits have been used as Moktong for thousands of years. This study was designed to determine discriminative criteria for identifying medicinal herbs used as Moktong. Methods : Akebia quinata, A. trifoliata, Clematis armandii, and Aristolochia manshuriensis were collected in various regions. Samples were authenticated and examined by observation and microscopy with paraffin embedding and triple staining using the modified Ju staining method. Results : Three different types of features to establish discriminative criteria for four kinds of Moktong were identified. Botanical features include differences in phyllotaxy, leaf shape, and caulescent. External morphological features were arrangement and size of fine holes(xylem), and overall shape of the section. Internal morphological features include the number of medullary rays, shape of the pitch, type of tissues rounding pitch, appearance of annual rings, shape and amount of crystals(calcium-oxalate), and the appearance of cork cambium. Further details(e.g. identification keys) are in the article. Conclusions : These criteria could provide an effective method for identifying numerous kinds of Moktong distributed in markets throughout northeast Asian nations.

주왕산국립공원의 특정식물 분포 특성분석 (Analysis on Characteristics of Distribution of Specific Plants in Juwangsan National Park, Korea)

  • 유주한;서정근;정성관
    • 한국환경과학회지
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    • 제22권7호
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    • pp.873-884
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    • 2013
  • This study was carried out to establish the conservation plan of specific plants by surveying and analyse the individuals and the environment of habitats on specific plants designated by Juwangsan national park office. The specific plants were 14 species including Berchemia berchemiaefolia, Hylotelephium ussuriense, Aristolochia manshuriensis, Lilium cernuum, Thalictrum coreanum, Exochorda serratifolia, Lilium distichum, Aristolochia contorta, Jeffersonia dubia, Eleutherococcus senticosus, Salix chaenomeloids, Eranthis stellata, Scopolia japonica, and Paeonia japonica. The habitats of specific plants were 40 sites including Berchemia berchemiaefolia of 11 sites, Hylotelephium ussuriense of 8 sites, Lilium cernuum and Thalictrum coreanum of each 3 sites, Exochorda serratifolia of 2 sites, and Lilium distichum, Aristolochia contorta, Jeffersonia dubia, Eleutherococcus senticosus, Salix chaenomeloids, Eranthis stellata, Scopolia japonica and Paeonia japonica of each 1 site. The altitude was the most in 300~400 m. In direction, NW was the most, and it showed SW in that order. The slope angle was the most in 0~10%, and the cliff showed in that order. In the results of species composition by stratum layer, Berchemia berchemiaefolia had the most, 15 species, in tree layer. In shrub and herb layer, this had the most as 20 species and 29 species, too. The species that occupied the largest size was Salix chaenomeloids in 2,500 $m^2$, and Jeffersonia dubia showed 1,500 $m^2$ in that order. The conservation of specific plants is to accomplish the ex situ and in situ conservation at the same time.

목통의 기원 및 사상의학적 효능 고찰 (Consideration on Origin and Efficiency in Sasang Constitutional Medicine of Mu tong)

  • 김명;유승엽;주종천
    • 대한한의정보학회지
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    • 제20권1호
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    • pp.1-8
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    • 2014
  • Objectives: This study aimed to find out the origin, efficiency in sasang constitutional medicine and dosage of Mu tong. Methods: Investigation and analysis was been done through 15 literatures like the pharmacopoeia of the five countries in east Asia, the literatures about sasang constitutional medicine and so on. Results and conclusion: The species of Mu tong in Korea is identical with the Mu tong in China, but different from Chuan mu tong and Guan mu tong in China. Mu tong is a kind of medicine using by kidney can be use at most 12 qian (about 45g) a day when treating heat closing in small intestine, edema, headache, dysentery and difficult urination on Soyangin(SY).

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한국 자생식물로부터 아라키돈산 대사계 효소 저해제 검색 (2) (Screening of Arachidonic Acid Cascade Related Enzymes Inhibitors from Korean Indigenous Plants (2))

  • 정혜진;문태철;이은경;손건호;김현표;강삼식;배기환;안인파;권동렬
    • 약학회지
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    • 제47권2호
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    • pp.69-77
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    • 2003
  • Arachidonic acid (AA), which is stored in membrane glycerophospholipids, is liberated by phospholipase $A_2$ (PLA$_2$) enzymes and is sequentially converted to cyclooxygenases (COXs) and lipoxygenases (LOXs) then to various bioactive PGs, and LTs. In order to find the specific inhibitors of AA metabolism especially PLA$_2$, COX-2, 5-LO and lyso PAF acetyltransferase, 120 Korean residential plants extracts were evaluated for their inhibitory activity on PGD$_2$, LTC$_4$ production from cytokine-induced mouse bone marrow-derived mast cells (BMMC) and arachidonic acid released from phospholipid and PAF production from lyso PAF. From this screening procedure, methanol extract of ten indigenous plant such as Salix gracilistyla, Sedum kamtschaticum, Cirsium chanroenicum, Hypericum ascyron, Astilbe chinensis, Agrimonia pilosa, Aristolochia manshuriensis, Vodia daniellii, Pyrola japonica, Styrax obassia were found to inhibit production of inflammatory mediators in vitro assay system.

주왕산국립공원 삼림식생의 군락분류와 군락생태 (Syntaxonomical and Synecological Description on the Forest Vegetation of Juwangsan National Park, South Korea)

  • 오해성;이경연;김종원
    • 한국환경생태학회지
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    • 제32권1호
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    • pp.118-131
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    • 2018
  • 주왕산국립공원의 삼림식생에 대한 식물사회학적 연구가 이루어졌다. 식물사회의 종조성과 서식처의 균질성을 강조하는 Z.-M. 학파의 방법으로 수행하였다. 52개 식생자료가 획득되었고, 출현식물 총 265분류군의 행동양식은 9계급의 변환통합우점도와 상대기여도를 통해 분석하였다. 식생자료의 모둠화 과정을 통해 단위식생을 분류하고, 그 분포와 현존균질도 등이 분석되었다. 4가지 상관우점식생 속에 9개 식물군락이 기재되었다: 신갈나무-애기감둥사초군락, 신갈나무-뱀고사리군락, 졸참나무-둥근잎천남성군락, 굴참나무-털조록싸리군락, 떡갈나무-털피나무군락, 서어나무-털대사초군락, 느티나무-등칡군락, 들메나무-개면마군락, 소나무-가는잎그늘사초군락. 삼림식생의 대상분포가 논의되었고, 표고 약 700 m가 냉온대 중부 산지대(신갈나무-생강나무아군단역)와 남부 저산지대(졸참나무-작살나무아군단역)의 전이대인 것으로 밝혀졌다. 주왕산국립공원의 삼림식생은 종조성의 낮은 균질성이 특징이었다. 결론적으로 주왕산국립공원의 삼림식생은 <지역생물기후구-대구형> 속에서 더욱 강한 대륙성 생물기후환경과 세립질 풍화토와 암편을 공급하는 유문암질 응회암 우세의 지질 환경에 대응하는 고유성이 큰 지역식생이고, 산불 영향이 더해진 근자연림 또는 이차림인 것으로 밝혀졌다.

통초(通草), 목통(木通) 신속 감별용 ITS 염기서열 기반 SCAR 마커 및 Multiplex-SCAR 분석법 개발 (Development of ITS sequence based SCAR marker and multiplex-SCAR assay for the rapid authentication of Tetrapanacis Medulla and Akebiae Caulis)

  • 노푸름;김욱진;박인규;양선규;최고야;문병철
    • 대한본초학회지
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    • 제36권1호
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    • pp.9-17
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    • 2021
  • Objectives : Tetrapanacis Medulla and Akebiae Caulis are one of the most frequently adulterated herbal medicines because of their confusability of terms in the ancient writings and the similarity of morphological features of dried herbal products. The major adulterant is Aristolochia manshuriensis (Guanmutong) which has a serious safety concern with its toxicity. To ensure the safety and quality of the two herbal medicines, it is necessary to discriminate the toxic adulterant from authentic species. The aim of this study is to develop SCAR markers and to establish the multiplex-SCAR assay for discrimination of four plant species related to Tetrapanacis Medulla and Akebiae Caulis. Methods : ITS regions of fifteen samples of four species (Tetrapanax papyrifer, Fatsia japonica, Aristolochia manshuriensis, and Akebia quinata) collected from different sites were amplified and sequenced. Fifteen obtained ITS sequences were aligned and analysed for the detection of species-specific sequence variations. The SCAR markers were designed based on the sequence alignments and then, multiplex-SCAR assay enhancing rapidity was optimized. Results : ITS sequences clearly distinguished the four species at the species level. The developed SCAR markers and multiplex-SCAR assay were successfully discriminated four species and detected the adulteration of commercial product samples by comparison of the amplified DNA fragment sizes. Conclusions : These SCAR markers and multiplex-SCAR assay are a rapid, simple, and reliable method to identify the authentic Tetrapanacis Medulla and Akebiae Caulis from adulterants. These genetic tools will be useful to ensure the safety and to standardize the quality of the two herbal medicines.

최근 독성 문제가 제기된 한약재에 대한 고찰 (A Review of Herbal Medicinal Products Associated with Toxic Events in Korea)

  • 장인수;양창섭;한창호
    • 대한한의학회지
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    • 제28권1호통권69호
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    • pp.1-10
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    • 2007
  • Background : There has been renewed interest in complementary alternative medicine around the world far a decade. On the other hand, the issue of safety of herbal medicine in Korea has been continuously questioned. Issues raised have included not only chemical residue or heavy metals caused by pollution, but also the toxicity of herbal medicine itself. Objectives : The purpose of this study was to review some herbal medicines subject to controversy of toxicity and figure out what kind of problems they evidence. Methods : In this review, PubMed was used to search medical journals. Keywords such as 'herb, or herbal medicine', 'safety, or adverse events, or adverse effect, or toxicity, or liver injury' were applied. Journals were selected by four inclusion criteria, as objectives should be human, researchers should be medical doctors, literature written in the English language, and types of journals should be meta-analysis or practice guideline or reviews. Finally, 9 cases from 60 journals were included in this review. Results : We reviewed 13 herbal medicines for controversy of toxicity such as ephedra(Mahuang), Arisolochia fangchi, Aristolochia manshuriensis, licorice, skullcap , germander, Syo-saiko-to(Xiao-chai-hu-tang), Chelidonium majus, mistletoe, Dictamnus dasycarpus and madder. Conclusions : It suggested that 'who it is prescribed for' is one of the most important factors to identify the causes of toxicity in herbal medicine and dietary supplements, under specific conditions in Korea.

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