• Title/Summary/Keyword: Antibacterial study

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A Study on the Antimicrobial Activity of Snowberry Extract (스노우베리 추출물의 항균 활성에 관한 연구)

  • Chanwoo Lee;Hye-Yeon Heo;Yu-Jin Park;YoungPyo Jang;Bo Ae Kim
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.2
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    • pp.283-291
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    • 2024
  • This study compared and evaluated the antibacterial activities and MIC of snowberry extract and fermented extract. For antibacterial activity, Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, and Candida Albicans were used. Antimicrobial activity and MIC were measured at concentrations of 10, 50, 100, and 200 mg/mL. Antibacterial activity was measured using the 8mm paper disc method. In the case of snowberry extract, it was confirmed that the root extract showed antimicrobial activity at concentrations of 100 mg/mL and 200 mg/mL, and in the case of fermented extract, it showed antimicrobial activity at 200 mg/mL. As a result of the MIC, for fermentation in snowberry leaf and root extracts, the minimum inhibitory concentration for each bacterium was confirmed in stem extracts. The above results indicate that the antibacterial properties of snow berries are improved by fermentation.

Antipseudomonal Activity and Nephrotoxicity of Cephradine-Netilmicin Combination

  • El Emam, M.A.;El Naggar, W.A.;Ibrahiem, T.M.
    • Archives of Pharmacal Research
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    • v.12 no.2
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    • pp.114-118
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    • 1989
  • The effects of intraperitoneal injection of cephradine in a dose of 75 mg/kg and netilmicin in dose of 50 mg/kg and their combination on creatinine and urea serum levels of rabbits were studied as well as the antipseudomonal activity against three multiresistant clinicial isolates. The antibacterial activity was investigated by two methods: Checkerboard titration method and time-kill studies. Finally, the antibacterial activity of the sera obtained from the rabbits receiving the used drugs in the previous regimen was studied using time-kill study method against Pseudomonas aeruginosa isolates. Results obtained from this study indicated that both creatinine and urea serum levels of the rabbits receiving both drugs were not significantly different from those of the rabbits receiving either cephradine or netilmicin alone. At the same time the in vitro antibactrial activity (either of the prepared solutions of the used drugs and their combination or of the sera obtained from the rabbits receiving these drugs as mentioned before) showed a synergistic effect against the tested strains of Pseudomonas aeruginosa

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A Study on Antimicrobial Activity of Veratri Herba (여로의 항균작용에 관한 연구)

  • Chi Gyoo Yong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.1
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    • pp.95-98
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    • 2002
  • This study was carried out to investigate the efficacy of antifungal and antibacterial activity of Veratri Herba, which was used as insecticide in the clinical part of oriental dermatology for a long time. Sample herb was selected with Veratrum maackii in the middle of 5 veratrum species. The experimental results of this herb were as follows. Crude extract showed various relative inhibitory rates from 68.9% to 95.6% in 2mg/disc against Fusarium oxysporum, Botrytis cineria, Saccharomyces cerevisiae, Escherichiae coli, and Bacillus subtilis on the basis of inhibitory range against B. cineria, and the inhibitory effect was decreased depending on density. In the extract of various organic solvent, chloroform and ethyl acetate fraction show the various size of dear zone against all microbes. And in the subfraction assay from ethyl acetate fraction, crude alkaloids show the antibacterial and antifungal effect significantly.

Effects of spawning on immune functions in the surf clam Mactra veneriformis (Bivalvia: Mactridae)

  • Yu, Jin-Ha;Choi, Min-Chul;Jung, Eun-Bin;Park, Sung-Woo
    • Journal of fish pathology
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    • v.24 no.1
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    • pp.19-27
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    • 2011
  • The production of surf clam, Mactra veneriformis, an important fishery resource in Korea, has recently been decreasing. This study was carried out to examine effects of spawning on immune functions of this species. Total hemocyte count (THC), phenoloxidase (PO) activity, phagocytic activity, neutral red retention (NRR) time and antibacterial activity were assessed. Spawned clams showed reduction in THC, PO, phagocytic activity and NRR times compared with unspawned ones. While spawning event did not elicit any change of antibacterial activity in both spawned and unspawned ones. This study indicates that spawning process decreases immune functions in the surf clams which could cause mortality increment and yield reduction.

Antibacterial Activity of Euphorbia humifusa Extracts on Food-Borne Pathogenic Bacteria (비단풀 추출물의 식중독세균에 대한 항균활성)

  • Choi, Moo-Young
    • The Korean Journal of Community Living Science
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    • v.21 no.1
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    • pp.13-18
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    • 2010
  • This study was performed to investigate the antimicrobial effects of Euphorbia humifusa ethanol-extract against food-borne pathogens. The growth inhibitory effects of the extract at a concentration of 250, 500, 1,000 or 2,000 mg/L on food poisoning microorganism were determined against Salmonella typhimurium, Listeria monocytogenes, Yersinia enterocolitica, Escherichia coli O157:H7 and Staphylococcus aureus. The microorganisms growth was not affected by the extract at the concentration up to 250 mg/L, but was significantly (p<0.05) inhibited by the extract at a concentration higher than 1,000 mg/L. The extract of Euphorbia humifusa had strong antimicrobial activity against all test strains at a concentration of 2,000 mg/L. The results in the present study demonstrate antimicrobial effects of Euphorbia humifusa ethanol-extract against food-borne pathogens, suggesting that Euphorbia humifusa could be an effective natural antibacterial agent in food.

Efficacy and safety of norfloxacin for the control of bacterial diseases in eel (Anguilla japonica)

  • Heo, Gang-joon
    • Korean Journal of Veterinary Research
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    • v.39 no.2
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    • pp.365-369
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    • 1999
  • A study on quinolone antibacterial, norfloxacin, was performed to apply for the control of bacterial diseases in eel (Anguilla japonica). Norfloxacin was proved excellent in antibacterial activity and sensitivity against fish bacterial pathogens when compared with the existing antibacterials and antibiotics. And any side effect was not observed during the period of indicated use. An outline of minimal inhibitory concentration was $0.03{\sim}0.1{\mu}g/ml$, $TLm_{48h}$ value was 3,500mg/l. The residual time of the day in fish body was less than 17 days and any pathological changes were not observed. The study has revealed that norfloxacin can be applied to treat some fish bacterial disease by the dosage of 100g/day/ton of fish body weight for about 3 days perorally. Further, norfloxacin may be used for the control of bacterial pathogens in eel.

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EXPERIMENTAL STUDY ON THE ANTIBACTERIAL EFFICACY OF A FEW FILLING MATERIALS (보존충전제(保存充塡劑)의 항균작용(抗菌作用)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Kim, Yung-Hai
    • Restorative Dentistry and Endodontics
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    • v.5 no.1
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    • pp.25-28
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    • 1979
  • The antibacterial efficacy of a few filling materials were studied in vitro. Zinc oxide eugenol cement. dycal, cavitec, hipol, cervident, clearfill and microfill were tested against Staphylococcus albus and Lactobacillus acidophilus on thioglycolate agar in order to determine whether the materials are effective inhibitors of bacterial growth. 1. Of these materials tested, zinc oxide eugenol cement was the most effective inhibitor of bacterial growth and revealed about 5.5mm in width of inhibition zone against Staphylococus albus and about 5.0mm against Lactobcillus acidophilus. 2. Dycal was moderate inhibitor of the both bact$\={e}$ria showing 2.5mm of the zone in width. 3. Cavitec was the slightest effect against the both bacteria 4. Composite resins tested in this study showed no evidence of inhibiting bacterial growth against the both bacteria.

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Effect of Natural Extracts on Oral Care Probiotics Weissella cibaria CMU and Periodontal Pathogens

  • Yeu, Ji-Eun;Kim, Hyun-Jin;Kang, Mi-Sun
    • International Journal of Oral Biology
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    • v.43 no.4
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    • pp.193-200
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    • 2018
  • The purpose of this study is to determine if natural extracts could be used as an additive in oral health food made with Weissella cibaria CMU (oraCMU). Natural extracts of green tea, mulberry leaf, licorice, and propolis, which are reported to have antimicrobial activities, were selected and used in this study. The minimum inhibitory concentrations (MIC) of extracts on periodontal pathogens such as Fusobacterium nucleatum and Porphyromonas gingivalis and their synergy effects with oraCMU by the fractional inhibitory concentrations methods were measured. From the results obtained, all the extracts showed no effect on the growth of oraCMU. Green tea extract showed the best antibacterial activity with MIC of 1.8 mg/ml against both F. nucleatum and P. gingivalis. In addition, green tea extract had a synergistic effect with oraCMU against F. nucleatum. Therefore, these results suggested that green tea extract is available as an additive in oral health food made with oraCMU.

The Effect of Body Wash Containing Triclosan and Bamboo Salt on Axillary Malodor (Triclosan과 죽염을 함유한 바디워시의 액취 등에 미치는 효과에 대한 연구)

  • Roh, Seok-Sun;Yun, Woo-Sik;Jung, Ji-Young;Yu, Hyung-Uk;Hwang, Dong-Sung;Choi, Seung-Man;Lee, Jeong-Rae;Kang, Sang-Jin;Chang, Sug-Youn
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.35 no.3
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    • pp.219-228
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    • 2009
  • This study was performed to evaluate a deodorant body wash with 1.0 wt% of triclosan and 0.4 wt% of bamboo salt, which have an inhibitory effect on axillary malodor. In this studies, in vitro antibacterial study and the clinical study, which was designed by randomized assignment, double-blind and cross-over, were performed. In the antibacterial study, test sample, which was body wash having 1.0 wt% of triclosan and 0.4 wt% of bamboo salt, have a potent antibacterial effect on Corynebacterium glutamicum, Corynebacterium xerosis, Corynebacterium jeikeium. In the clinical study, test sample has a potent and significant deodorizing effect on axillary malodor and an antibacterial efficacy. And its efficacy was maintained for 9 h at least. There was no side effect during the period of clinical study. Consequently, body wash, containing 1.0 wt% of triclosan and 0.4 wt% of bamboo salt, has the effectiveness and the safety about axillary malodor reduction.