• Asian Pacific Journal of Cancer Prevention
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• v.17 no.1
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• pp.369-372
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• 2016

Background: Acute myeloid leukemia is an acquired clonal heterogeneous stem cell disorder. Hence, various parameters are sought out to categorize this disease into subtypes, so that as a consequence specific treatment modalities can be offered. Conventionally, the practically used method for classification utilizes French American British (FAB) criteria based on morphology and cytochemistry. The aim of present study was to determine the current spectrum of AML sub types in patients in Karachi. Materials and Methods: This single centre cross sectional study was conducted at Liaquat National Hospital, Karachi, extending from January 2010 to December 2014. Data were retrieved from archives were analyzed with SPSS version 22. Results: A total of 125 patients were diagnosed at our institution with de novo AML during five years period, 76 males and 49 females. Median age was 34.5 years. AML-M1 was the predominant FAB subtype (23.2%) followed by M2 (18.4%), M3 and M4 (16% each), M0 (14.4%), M5 (7.2%), M6 (3.2%) and M7 (1.6%). Conclusions: AML in Pakistani patients is seen in a relatively young population. The most common FAB subtype observed in our study was acute myeloblastic leukemia, without maturation (M1).

• Archives of design research
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• v.11
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• pp.1-9
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• 1995

Scandinavian design has special meaning in design history. Especially the Swedish designers have developed elegant and humane design style by combining the functionalism originated in Germany in the beginning of 20th century with their own crafts tradition. Now 'Swedish Modern' or 'Swedish Grace' is regarded as the most preferrable style for modern industrial society. American design as well as European design has been much changed under the influence of this democratic, simple and beautiful style. To find out the essential qualities of Swedish design style, I want to investigate the history of modern Swedish design and the design mechanism in Swedish corporates. Also I want to introduce the design education system in Sweden, which has contributed to developing contemporary Swedish design philosophy.

• Archives of design research
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• v.15 no.1
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• pp.81-92
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• 2002

Through network draft, it′s possible to describe curve draft with main motive in a lobby loom and to fulfill draft design more conveniently thanks to the development of computer device. Network draft was introduced by Alice Schlein, who is an American weaving artist, and I had ever published research paper on "The unfolding and development of network draft using computer dobby system" . The purpose of the next study was to develop the design of network draft while do make a design network draft in a dobby loom with 16 shafts, and could reach follow conclusion as a result of designing a variety of drafts. The initial of 4-end in a loom with 16 shafts was a basic condition to describe more perfect shape in comparison with draft in 8 shafts through the development of network. The development of draft line was essential to deride the pattern of fabric, and the pattern of draft is decided according to selecting key peg plan. Thereby, could get a variety of draft patterns derive from mix key peg plan with initial selected by developing the kind of draft line and applying diverse key peg plan. As for the variation and diversification of draft line, the shape of patters varied depending col the curve extent and connectivity of draft line and the size of curve. The pattern of network draft can be changed infinitely by free round curve of draft line. In addition, a variety of draft designs shall be developed by increasing the number of shaft, enlarging the scale of draft line, and developing more creative draft line.

• Archives of Pharmacal Research
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• v.23 no.4
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• pp.418-423
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• 2000

Oka strain VR-795 (Varicella Zoster Virus, VZV) of American Type Culture Collection (ATCC) has been used for chickenpox vaccine production. In order to use this strain for vaccine production, the strain must be identified and its stability must be confirmed. The identification of the Oka strain has been confirmed using Restriction Fragment Length Polymorphism (RFLP) and DNA sequence analysis of glycoprotein-II (gp-II). The amino acid sequences of Oka deduced from the DNA sequence of gp-II have changed at three amino acids against Ellen and at one amino acid against Webster. To prove the stability of the Oka strain during the passage, RFLP and DNA sequence analyses were also used with 11, 15 and 23 times of virus passage. We found that the Oka strain was stable at passages of up to 23 times, based on the RFLP and DNA sequence analyses. The confirmed Oka strain was renamed as BR-Oka for the purposes of chickenpox vaccine production.

• The Korean Journal of Archival Studies
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• no.8
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• pp.181-211
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• 2003

The purpose of this study is to reveal the context within which EAD was developed, to review the elements and the structure of EAD 1.0 version and to introduce EAD as new standard for encoded archival finding aids in Korea. Encoded Archival Description(EAD) has been developed in 1993 in order to facilitate exchange of ISAD(G) descriptive information. EAD is currently administered and maintained jointly by the Society of American Archivists and the United States Library of Congress. While development was initiated in the United Stares, international interest and contribution are increasing. EAD is a encoding standard designed specifically for marking up information contained in archival finding aids. From its inception, EAD was based on SGML, and, with the release of EAD version 1.0 in 1998, it is also compliant with XML in order to facilitate easier internet access to SGML-encoded finding aids. EAD is the first tool to preserve the multilevel and hierarchical description manifest in finding aids by providing structures in which to describe entire record collections and increasingly smaller subcomponents thereof such as series, subseries, folders, and even items. Archival institutions can form a EAD consortium and also create a union database of EAD finding aids for the geographically dispersed collections. The EAD DTD provides a flexible way for archives to convert finding aids that exist in paper form into electronic documents or to create new finding aids in electronic form.

• Archives of design research
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• v.13
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• pp.177-200
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• 1996

The purpose of this study is to show the textile designers how to be creative and how to accept other ideas which are not necessarily of their own, and to show what exactly creating anything means. During the 1950's and'60s. America and Europe reached their peak in developing their consumption culture. After World War II, America achieved an astonished feat in developing its thechnology and industry to cause the economy to a rapid ascendence. The U.S. government adopted the Keynsian theory in its economic policy. The Keynsian theory advocates the consumer spending. And during this time period the American public developed consumption habit. Mass production and mass media went in hand to induce the public to buy. The public became an important target for the advertising stratages of the industry. In order for the industry to advertise the mass produced products, it had to utilize the mass media such as television, newspaper, and magazine. And mass media came into play an important role not to advertise the products, but to imform and educate the public about the products. This corporate stratege is further enhanced by the desire of the American public to climb up the ladder by way of material possession. Pop Art was born not only in reflecting the ideology of the consumption culture, but acted as a catalyst for more spending. The subjects of Pop Art are cars, foods, comics, Hollywood actors and movie scenes, the famous singers or persons. Andy Warhol specifically used the chosen image repeatedly to emphasize the redundacy of the image. The common factors which exist between Andy Warhol's Pop Art and textile design is the repetition in form, and the way of transferring an image to a canvas - Warhol used the frotttage technique to transfer an image to a canvas and textile design is transferred to a paper by way of transferring technique. Also the way Warhol thought of his paintings as a decorative elements and made a couple of his paintings into wallpapers or exhibits his painstings wall to wall demonstrates his close alliance with the textile design, let alone his comercial design background. In this study, I examined the inter-relationship between textile design and Pop Art. To carry out this study, I examined the comsumption culture: and the biomorphic relationship of culture and art: and Pop art and its transience stage. The major finding of this study is there exists a common denomenator between textile design and Pop Art, especially of Andy Warhol's.

• Archives of design research
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• v.16 no.2
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• pp.161-170
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• 2003

This study aims to understanding the effects of culture on websites with emphasis on the website structure and navigation. The website is inherently‘cultural’because anyone around the world can access to website if he or she is equipped with appropriate equipment. For the importance of cultural role in website, various researches have been conducted to understand the relationship between culture and website. However they tended to focus mainly on phenomenal matters such as color, layout, icon etc. There have been not so many thorough attempts to causal relationships between website and‘thick culture’in depth. The study conducted cross-cultural usability testing of websites between Korea and America. At first, representative I-commerce websites of Korea and America were selected and they were analyzed by the selected frameworks such as layout, display type, element type, and the relationship with homepage and sub-page navigation. The results were used to construct typical prototypes of website for Korea and America for experiment. Two websites were used for cross-cultural usability testing though specially-developed remote testing. 20 users from each country participated in the usability testing. The result shows that Korean users peformed better usability testing for Korean style structure of website while American counterparts showed better performances in American style of websites. Other various significant findings were revealed.

• Archives of Plastic Surgery
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• v.33 no.3
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• pp.289-293
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• 2006

By means of microsurgical free-tissue transfer providing a large amount of required tissue, the surgeon can resect tumoral tissue more safely, which allows tumor-free margins and enhances the reliability of the ablative surgery that otherwise could not be performed radically. The morbidity of elective free-tissue transfer seems to be quite low, carrying acceptable risks for most patients. But the elderly patients are at risk for cardiac and respiratory problems, deep vein thrombosis, pulmonary emboli and infection merely as a function of age. This study was undertaken to define further risks of the elderly population with regards to free-tissue transfer. We retrospectively reviewed our experience with 110 microsurgical free-tissue transfers for head and neck reconstruction in patients greater than 60 years of age. Microsurgical procedures in all cases were preformed by the plastic and reconstructive department at Yonsei medical center. The investigated parameters were patient demographics, past medical history, American Society of Anesthesiologists(ASA) status, site and cause of defect, the free tissue transferred and postoperative complication including free-flap success or failure. There were 46 patients in the age group from 60 to 64 years, 34 patients from 65 to 70 years, and 30 patients 70 years or older. There happened 3 flap losses, resulting in a flap viability rate of 97%. Patients with a higher ASA designation experienced more medical complication(p=0.05, 0.01, 0.03 in each age group I, II, III) but not surgical complication p=0.17, 0.11, 0.54 in each age group I, II, III). And the relationship between postoperative complication and age groups was not significant. These observations suggest that major determinant for postoperative medical complication be the patient's American Society of Anesthesiologists score, and chronologic age alone should not be an exclusion criterion when selecting patients for free-tissue transfer

• Archives of Plastic Surgery
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• v.46 no.4
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• pp.336-343
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• 2019

Background Sternal rigid plate fixation (RPF) has been adopted in recent years in high-risk cases to reduce complications associated with steel wire cerclage, the traditional approach to sternal closure. While sternal RPF has been associated with lower complication rates than wire cerclage, it has its own complication profile that requires evaluation, necessitating a critical examination from a national perspective. This study will report the outcomes and associated risk factors of sternal RPF using a national database. Methods Patients undergoing sternal RPF from 2005 to 2016 in the American College of Surgeons-National Surgical Quality Improvement Program were identified. Demographics, perioperative information, and complication rates were reviewed. Logistic regression analysis was performed to identify risk factors for postoperative complications. Results There were 381 patient cases of RPF identified. The most common complications included bleeding (28.9%), mechanical ventilation >48 hours (16.5%), and reoperation/readmission (15.2%). Top risk factors for complications included dyspnea (odds ratio [OR], 2.672; P<0.001), nonelective procedure (OR, 2.164; P=0.010), congestive heart failure (OR, 2.152; P=0.048), open wound (OR, 1.977; P=0.024), and operating time (OR, 1.005; P<0.001). Conclusions Sternal RPF is associated with increased rates of three primary complications: blood loss requiring transfusion, ventilation >48 hours, and reoperation/readmission, each of which affected over 15% of the study population. Smokers remain at an increased risk for surgical site infection and sternal dehiscence despite RPF's purported benefit to minimize these outcomes. Complications of primary versus delayed sternal RPF are roughly equivalent, but individual patients may perform better with one versus the other based on identified risk factors.

• Journal of Korean Library and Information Science Society
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• v.40 no.3
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• pp.271-293
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• 2009

A Records manager and archivist should have the academic knowledge and working ability due to the working character. Archives and records centers are being changed with developing information technology so that they are requiring a records manager and archivist to have a professional working ability through a variety of practice. However, in recent, the curriculum of Korean archival graduate schools focuses on a theoretical field and neglects to apply a theory to a working field. Therefore, in this paper, the writer compares some elements to improve the working ability shown in the curriculum of Korean and American archival graduate programs, and suggests the method to cultivate a theoretical knowledge as well as working ability. The cultivating ways the writer suggests are as follows: To improve the working ability in a practical field of the curriculum of archival graduate school in Korea, the writer suggests -- 1. increasing the grades of major field and college courses, and changing the practice subject to an obligatory subject, and 2. developing an internship program for a full practice with company, government, and college, and 3. operating a continuous training program that an records manager engaging in records center and archives can acquire a new knowledge and technology and apply the professionalism to a working field.