• Hwankyungkyoyuk
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• v.24 no.4
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• pp.51-61
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• 2011

In this study, the Korean alternative school teachers' perceptions of ecocentric environmental education were surveyed. A total of 80 teachers from 42 alternative schools across the nation answered to the survey. The results were as follows. Teachers were found to have a lot of interest in environmental issues and to practice some environmental actions inside and outside school. Over sixty percent teachers agreed with the ecocentric philosophy of environmental education. The most two important issues among 11 environmental education contents for teachers were "natural environment" and "environmental ethics". Teachers used and preferred "field work" for teaching environmental issues, and got teaching materials mostly from the internet. However, many of them were not satisfied with environmental activity in their schools because of their lack of professionalism. They had not enough experience of professional development for environmental education, and strongly wanted to learn about field work.

• Herbal Formula Science
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• v.17 no.2
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• pp.85-98
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• 2009

The fruits of Schisandra chinensis and Prunus mume have been traditionally used in the Oriental countries as an astringent against diarrhea and abdominal pain, a protectant for liver disease, an antimicrobial, and a blood tonic. However, little is known about the extract of Schizandrae Fructus and Mume Fructus (SMF-Ex) on dextran-sulfate sodium (DSS)-induced colitis in mice. In this study, we investigated the protective effects of SMF-Ex on DSS-induced colitis in mice. An experimental colitis was induced by daily treatment with 5% DSS. SMF-Ex was orally administrated the single dose (80 mg/kg, body weight/day) for 7 days with one time per day. SMF-Ex reduced significantly clinical sign of DSS-induced colitis, including body weight loss, shorten colon length, increased disease activity index (DAI), and histological colon injury. SMF-Ex also inhibited significantly nitric oxide (NO) and prostaglandine $E_2$ ($PGE_2$) productions in DSS-induced colitis mice. Furthermore, SMF-Ex increased significantly an superoxide anion (SOD), catalase, and glutathione peroxidase (Gpx) activity of the colon tissue in DSS-induced colitis mice. These results suggest that SMF-Ex administration could reduce significantly the clinical signs and inflammatory mediators, and increase antioxidant activity in DSS-induced colitis model mice and is a good candidate for further evaluation as an effective anti-ulcerative agent.

• Journal of The Korea Institute of Healthcare Architecture
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• v.15 no.4
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• pp.3-11
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• 2009

As de-schooling students (students who leave schools) have been produced and increased in middle and high schools every year since 1990s, urban alternative schools have founded with Seoul as the center. The objects of such urban alternative schools are de-schooling teenagers, and their educational goal is to make the students to discover their own values and grow as members of the community by accomplishing their healing and growth. Most of students in alternative schools have excessive self-centered feeling than ordinary people, and since they don't have exchanges with others, they have to receive holistic healing along with education. Here, 'healing' is a method of approaching to health through environmental, psychological, social and cultural supports unlike 'treatment' used for medical means. Therefore, holistic healing for alternative schools' students has to accomplish self-knowledge, self-control, and self-healing without repulsion through spaces of healing environments instead of heavy-handed exchanges. This study has integrated a theory of Max $L{\ddot{u}}scher$ who suggested a psychological healing theory in terms of internal character and a theory of Rudolf Steiner who suggested it in terms of practical and holistic sense and analyzed Sungmisan School, one of urban alternative schools in Seoul through the integrated theory. The analysis of the integrated theory are intended to emphasize the importance of healing environments and suggest methods in creating healing environments for urban alternative schools in the future.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.3
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• pp.63-73
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• 2013

Objectives : The aim of the study was to investigate major satisfaction, career choices and perceived career barriers in college students majoring in alternative medicine. Methods : A total of 315 college students majoring in alternative medicine in 5 universities in K city and J province completed survey questionnaires. Results : The highest proportions of students (38.4%) chose alternative medicine major because of their aptitude and interest. Students (59.0%) were satisfied in general with their majors. Regarding career direction after graduation, the highest proportions 1st of and 2nd year students answered that they haven't decided yet (33.7%). In addition, they wanted to get a job in hospitals (24.6%) and have more education (21.9%). The highest proportions of 3rd and 4th year students wanted to get a job in hospitals (31.3%) and 27.3% of them wanted to have more education. The most important criterion for choosing a career was a career aptitude (38.7%) followed by professionalism, vision, pay, and social status in both groups. Regarding perceived career barriers, the highest proportions of 1st and 2nd year students (31.6%) answered the lack of social recognition about alternative medicine while the highest proportions of 3rd and 4th year students (55.5%) answered the lack of national certifications (P<0.001). Conclusions : In general, students majoring in alternative medicine were satisfied with their majors. They wanted to get a job at a hospital and have more education. They thought that the lack of social recognition and national certification of alternative medicine would be career barriers.

• Child Health Nursing Research
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• v.13 no.3
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• pp.247-256
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• 2007

Purpose: This study was done to examine the experience of school health instructors in applying complimentary and alternative medicine (CAM). Method: The participants were 215 health instructors working in elementary schools in Busan. Data were collected from Dec. 1, 2004 to Mar. 10, 2005 and were analyzed using SPSS WIN 10.0. Results: Most of the health instructors had knowledge about CAM. Among the various CAM methods, acupuncture was the most widely known at 78.6%. While 53.5% had no experience in CAM education, 46.5% had been trained. Slightly over half (52.1%) had used CAM at school and based their decision on personal experience. As to applicability of CAM at school, 72.1% thought CAM was applicable, and 78.7% of this group considered alleviation of symptoms and assistance in the treatment process as the reasons for their answer. There were significant differences in responses as to the applicability of CAM according to age (p=.002), work experience (p=.004) and educational background (p=.002). Conclusions: The above results suggest that there is a need to develop a professional education program on complimentary and alternative medicine to assist school health instructorsto plan nursing interventions using CAM which are individualized and practical.

• The Korean Journal of Food And Nutrition
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• v.29 no.4
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• pp.557-564
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• 2016

This study was performed to develop and evaluate beverage prepared with optimally roasted seoritae to maximize the isoflavone content and antioxidant activities of the beverage. Isoflavone content was maximized at the roasting temperature of $110^{\circ}C$ for 20 min. Both DPPH radical scavenging activity and ABTS radical scavenging activity along with total polyphenol content were highest when seoritae was roasted at $110^{\circ}C$ for 20 min. Western blotting was used to determine the level of nuclear factor of activated T-cells 1(NFATc1) involved in controlling osteoclast differentiation. The results showed that NFATc1 had a concentration-dependent inhibitory effect when the RoS110 (roasted seoritae at $110^{\circ}C$ for 20 min) samples were processed at varying concentrations (10, 50, and $100{\mu}g/mL$). Tea samples were prepared from optimally roasted seoritae by varying brewing times (5~90 min) at $65^{\circ}C$, and tea brewed for 60 min had the highest preference with $65^{\circ}C$ as the preferred temperature for drinking.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2153-2158
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• 2014

Beclin 1 is a key factor for initiation and regulation of autophagy, which is a cellular catabolic process involved in tumorigenesis. To investigate the role of alternative splicing of Beclin1 in the regulation of autophagy in leukemia cells, Beclin1 mRNA from 6 different types of cell lines and peripheral blood mononuclear cells from 2 healthy volunteers was reversely transcribed, subcloned, and screened for alternative splicing. New transcript variants were analyzed by DNA sequencing. A transcript variant of Beclin 1 gene carrying a deletion of exon 11, which encoded a C-terminal truncation of Beclin 1 isoform, was found. The alternative isoform was assessed by bioinformatics, immunoblotting and subcellular localization. The results showed that this variable transcript is generated by alternative 3' splicing, and its translational product displayed a reduced activity in induction of autophagy by starvation, indicating that the spliced isoform might function as a dominant negative modulator of autophagy. Our findings suggest that the alternative splicing of Beclin 1 might play important roles in leukemogenesis regulated by autophagy.

• Molecules and Cells
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• v.37 no.1
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• pp.81-87
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• 2014

Chronic pressure-overload cardiac hypertrophy is associated with an increased risk of morbidity/mortality, largely due to maladaptive remodeling and dilatation that progresses to dilated cardiomyopathy. Alternative splicing is an important biological mechanism that generates proteomic complexity and diversity. The recent development of next-generation RNA sequencing has improved our understanding of the qualitative signatures associated with alternative splicing in various biological conditions. However, the role of alternative splicing in cardiac hypertrophy is yet unknown. The present study employed RNA-Seq and a bioinformatic approach to detect the RNA splicing regulatory elements involved in alternative splicing during pressure-overload cardiac hypertrophy. We found GC-rich exonic motifs that regulate intron retention in 5' UTRs and AT-rich exonic motifs that are involved in exclusion of the AT-rich elements that cause mRNA instability in 3' UTRs. We also identified motifs in the intronic regions involved in exon exclusion and inclusion, which predicted splicing factors that bind to these motifs. We found, through Western blotting, that the expression levels of three splicing factors, ESRP1, PTB and SF2/ASF, were significantly altered during cardiac hypertrophy. Collectively, the present results suggest that chronic pressure-overload hypertrophy is closely associated with distinct alternative splicing due to altered expression of splicing factors.

• Animal Bioscience
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• v.36 no.7
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• pp.1091-1100
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• 2023

Objective: The present study is to examine the effect of high inclusion of co-products in pig diets (referred to as an alternative diet) during the finishing stage on pig growth performance, meat quality and boar taint compounds. Methods: Growing pigs were fed an alternative diet made with distillers dried grains with solubles (25%), canola meal (20%), and wheat middling (15%) or a control diet based on barley and soybean meal to investigate the impact of co-products on pig performance and meat quality. Sixteen female and sixteen entire male Duroc×(Large White×Landrace) pigs (22.6±2.07 kg, body weight±standard error) were equally allocated to the diets. Results: Pigs fed the alternative diet had a lower feed intake; however, growth rate and feed conversion efficiency were unaffected by diet. A diet by sex interaction was found for gain:feed whereby males fed the alternative diet had the best feed conversion (p<0.01). Pork from pigs fed the alternative diet had lower a^* and Chroma and protein % (p<0.05), while other meat quality characteristics were unaffected. The alternative diet reduced backfat skatole levels (p<0.001). Conclusion: A diet containing high inclusion levels of co-products can be fed to pigs during the finishing stage without detrimental effects on pig performance or meat quality and with the potential to enhance pork flavour. This finding suggests a solution to increase the sustainable development of pig production.

• Journal of Christian Education in Korea
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• v.63
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• pp.183-219
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• 2020

The purpose of this study is to find out what their professionalism is and how their expertise grows among Christian alternative school teachers. Professionalism refers to the broad expertise such as specific knowledge, skills, and attitudes needed for a particular profession. The teacher expertise is also closely related to the life cycle of a teacher. The present study collected and analyzed the data using a mixed research method that combined a survey and interview. The survey, which involved 276 Christian alternative school teachers, asked about the current teacher's interest, the importance and retention of each element of professionalism, and, in addition, the level of external efforts and help in developing professionalism. The in-depth interview was conducted on 7 Christian alternative school teachers and identified the meaning of teacher professionalism, teacher quality and competencies, and environment for the professional growth. The results reveal that the professionalism recognized by Christian alternative school teachers is rather complex. It includes communication and relationship, calling and identity in addition to the curriculum and instruction expertise that reconstructs the curriculum from a Christian perspective. It is further found that teachers' decision to respond to the calling, subsequent continuous self-development, the teacher community that embodies such calling and efforts, and the school environment where autonomy and responsibility coexist, are equally important for their professional growth. Thus, in order to promote the professionalism of Christian alternative school teachers more effectively in the future, it would be necessary to provide programs that take the teacher's whole life cycle into account and are also directed to teachers themselves rather than to institutions. Considering the emphasis on the expertise in communication and relations, pre-service teacher education should focus not only on developing subject matter expertise, but also fostering communication and relational skills with students and other school community members.