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Exploration and Development of the Taebaek Orebody in the Yeonwha Pb-Zn Mine (연화광산(蓮花鑛山)의 태백광체탐사(太白鑛體探査)와 개발현황(開發現況))

  • Je, Young-Kun;Lee, Eun-Jae
    • Economic and Environmental Geology
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    • v.20 no.4
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    • pp.273-288
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    • 1987
  • 연화(蓮花) 연(鉛) 아연광산(亞鉛鑛山)은 광체(鑛體)의 분포(分布)에 따라 본산지구(本山地區), 동점지구(銅店地區) 및 태백지구(太白地區)로 구분할 수 있다. 태백지구(太白地區)에 대한 본격적인 탐광(探鑛)이 시작되기 전인 1981년 당시, 약 25년 동안 채광작업(採鑛作業)이 진행되어 온 본산지역(本山地域)은 주종광체(主宗鑛體)인 월암(月岩) 및 남산광체(南山鑛體)가 -600m level에서 하한(下限)이 드러남에 따라 광량(鑛量)이 크게 소진(消盡)된 상태였으며, 동점지성(銅店地城)은 상하(上下)의 광황변화(鑛況變化)는 크지 않으나 광체(鑛體)의 규모(規模)가 비교적 작아, 조업(操業)의 안정(安定)을 위해서는 신광화대(新鑛化帶)의 개발(開發)이 시급(時急)한 과제(課題)로 대두되었다. 이에 따라 평천(平川), 태백(太白), 동점역(銅店驛), 방터골, 삼방산광화대(三芳山鑛化帶) 등 연화(蓮花) 전역(全域)에 걸쳐 모암(母岩)의 분포(分布), 지질구조(地質構造), 광징(鑛徵) 등을 검토한 결과 탐광대상(探鑛對象)에서 제외되어 왔던 태백지구(太白地區)가 다음과 같은 점에서 유망(有望)한 탐사후보지(探査候補地)로 부각되었다. 첫째, 지표(地表)에서는 풍촌석회암층(豊村石灰岩層)이 분포(分布)되지 않으나 지질구조(地質構造)를 검토한 결과 -300m level 하부(下部)에서는 이의 전층(全層)이 분포(分布)할 것으로 예상되며, 둘째, 두무동층(斗務洞層) 및 동점규암층내(銅店珪岩層內)에서 발견된 광징(鑛徵)들이 하부(下部)의 풍촌석회암내(豊村石灰岩內)로 연장(延長)되면 부광부(富鑛部)를 이룰 것으로 기대되고, 셋째, 지층(地層)의 경사(傾斜)가 $50^{\circ}$ 이상(以上)인 점, 석영반암(石英斑岩)이 분포(分布)하는 점 등은 광상배태(鑛床胚胎)에 양호(良好)한 조건(條件)이고, 넷째, 본산지구(本山地區)의 월곡(月谷), 월암(月岩), 남산(南山)등 주종광화대(主宗鑛化帶)의 연장부(延長部)인 점, 다섯째, 중앙견갱(中央堅坑)으로부터 약 2km 거리로 탐사단계(探査段階)에 별도의 신규투자(新規投資) 없이 굴진(掘進)이 가능하다는 개발조건상(開發條件上)의 이점(利點)이 있었다. 이에 따라 태백지구(太白地區)에 대한 지표정사(地表精査), 물리탐사(物理探査) 및 지화탐(地化探)을 실시하고, 20여년간 축적된 연화광산(蓮花鑛山)의 지질(地質), 광상자료(鑛床資料)를 정리(整理), 그 특성(特性)을 태백지구(太白地區) 탐사(探査)의 가설(假說)로 적용하여 시추계획(試錐計劃)을 수립, 1982년 구조시추(構造試錐)를 실시한 결과 지질구조(地質構造), 풍촌석회암층(豊村石灰岩層)의 분포(分布) 등이 거의 예상했던 대로 밝혀졌으며 태백(太白) 1호광체(號鑛體)의 일단(一端)이 확인되기에 이르렀다. 1983년(年) 7월(月) 본산지구(本山地區) -600m level에서 태백(太白) 크로스 탐광굴진(探鑛掘進)이 착수되었으며, 1985년에 마침내 갱내(坑內)에서 태백(太白) 1호(號), 2호(號) 광체(鑛體)가 착광(着鑛)되었다. -600m level에서의 태백(太白) 1호광체(號鑛體)의 규모(規模)는 연장(延長) 300m, 평균맥폭(平均脈幅) 8.5m이며, 품위(品位)는 Pb 4.5%, Zn 4.5%, Ag 109g/t이다. 태백광화대(太白鑛化帶)의 지질학적(地質學的) 예상광량(豫想鑛量)은 1,000만(萬)t 이상(以上)이 될 것으로 추정(推定)되며, 현재 -480m level에서 -720m level에 이르기까지 5개 level에서 가행(稼行)되고 있다. 현재 level에서 태백(太白) 1호(號) 광체(鑛體)는 풍촌석회암층(豊村石灰岩層) 및 화절층(花折層)을 모암(母岩)으로 하여 맥상광상(脈狀鑛床)으로 생산(生産)되며, 맥석광물(脈石鑛物)은 능망간석, Mn-방해석(方解石), 방해석(方解石), 석영(石英) 등이고 광석광물(鑛石鑛物)은 섬아연석(閃亞鉛石), 방연석(方鉛石), 황철석(黃鐵石), 자유철석(磁硫鐵石), 유비광석(硫砒鑛石), 황동석(黃銅石), 사면동석(四面銅石), 엘렉트럼 등이다. 태백지구(太自地區)는 광상(鑛床)의 산출상태(産出狀態) 및 지질(地質), 광상학적(鑛床學的) 환경(環境)이 본산지구(本山地區)와 거의 동일(同一)함이 밝혀지고 있다. 태백지구(太白地區)에서는 현재 태백(太白) 1호(號), 2호(號), 3호(號), 5호(號) 및 절골 1호(號), 2호(號) 등 6개 광화대(鑛化帶)에 대한 탐광(探鑛)이 진행되고 있다.

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Mesothermal Gold-Silver Mineralization at the Bodeok Mine, Boseong Area : A Fluid Inclusion and Stable Isotope Study (전남(全南) 보성지역(寶城地域) 보덕광산(寶德鑛山)의 심부(深部) 중온형(中溫型) 금(金)-은(銀) 광화작용(鑛化作用): 유체포유물(流體包有物) 및 안정동위원소(安定同位元素) 연구(硏究))

  • So, Chil-Sup;Yun, Seong-Taek;Kim, Se-Hyun;Youm, Seung-Jun;Heo, Chul-Ho;Choi, Seon-Gyu
    • Economic and Environmental Geology
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    • v.26 no.4
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    • pp.433-444
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    • 1993
  • Electrum (32~73 atom. % Ag)-sulfide mineralization of the Bodeok mine in the Boseong area was deposited in two stages of mineralogically simple, massive quartz veins that fill the fractures along fault shear zones in Precambrian gneiss. Radiometric dating indicates that mineralization is Late Jurassic age ($155.9{\pm}2.3$ Ma). Fluid inclusion data show that ore mineralization was formed from $H_2O-CO_2$ fluids with variable $CO_2$ contents ($X_{CO_2}=0.0$ to 0.7) and low salinities (0.0 to 7.4 wt. % eq. NaCl) at temperatures between $200^{\circ}$ and $370^{\circ}C$. Evidence of fluid unmixing ($CO_2$ effervescence) indicates pressures up to 1 kbar. Gold-silver deposition occurred later than base-metal sulfide deposition, at temperatures near $250^{\circ}C$ and was probably a result of cooling and decreasing sulfur activity caused by sulfide precipitation and/or $H_2S$ loss (through fluid unmixing). Calculated sulfur isotope compositions of ore fluids (${\delta}^{34}S_{{\Sigma}S}=1.7$ to 3.3‰) indicate an igneous source of sulfur in hydrothermal fluids. Measured and calculated O and H isotope compositions of ore fluids (${\delta}^{18}O_{water}=4.8$ to 7.2‰, ${\delta}D_{water}=-73$ to -76‰) indicate that mesothermal auriferous fluids at Bodeok were likely mixtures of $H_2O-rich$, isotopically evolved meteoric waters and magmatic $H_2O-CO_2$ fluids.

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Mineralogy and Genetic Environments of the Seongdo Pb-Zn deposit, Goesan (괴산 성도 연-아연 광상의 산출광물과 생성환경)

  • Ahn, Seongyeol;Shin, Dongbok
    • Economic and Environmental Geology
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    • v.50 no.5
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    • pp.325-340
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    • 2017
  • The Seongdo Pb-Zn deposit, located in the northwestern part of the Ogcheon Metamorphic Belt, consists of skarn ore replacing limestone within the Hwajeonri Formation of Ogcheon Group and hydrothermal vein ore filling the fracture of host rock. Skarn minerals comprise mostly hedenbergitic pyroxene, garnet displaying oscillatory zonal texture composed of grossular and andradite, and a small amount of wollastonite, tremolite, and epidote, indicating reducing condition of formation. Ore minerals of skarn ore include sphalerite and galena with a small amount of pyrite, pyrrhotite, and chalcopyrite. In hydrothermal vein ore, arsenopyrite, sphalerite, chalcopyrite, and pyrite occur with a small amount of galena, native Bi, and stannite. Chemical compositions of sphalerite vary from 17.4 mole% FeS in average for dark grey sphalerite, 3.6 mole% for reddish brown sphalerite in skarn ore, and to 10.3 mole% FeS in hydrothermal vein ore. In comparison with representative metallic deposits in South Korea on the FeS-MnS-CdS diagram, skarn and hydrothermal vein ore plot close to the field of Pb-Zn deposits and Au-Ag deposits, respectively. Arsenic contents of arsenopyrite in hydrothermal vein ore decrease from 31.93~33.00 at.% in early stage to 29.58~30.21 at.% in middle stage, and their corresponding mineralizing temperature and sulfur fugacity are $441{\sim}490^{\circ}C$, $10^{-6}{\sim}10^{-4.5}atm$. and $330{\sim}364^{\circ}C$, <$10^{-8}atm$. respectively. Phase equilibrium temperatures calculated from Fe and Zn contents for coexisting sphalerite and stannite in hydrothermal vein are $236{\sim}254^{\circ}C$. Sulfur isotope compositions are 5.4~7.2‰ for skarn ore and 5.4~8.4‰ for hydrothermal vein ore, being similar or slightly higher to magmatic sulfur, suggesting that ore sulfur was mostly of magmatic origin with partial derivation from host rocks. However, much higher sulfur isotope equilibrium temperatures of $549^{\circ}C$$487^{\circ}C$, respectively for skarn ore and hydrothermal ore, than those estimated from phase equilibria imply that isotopic equilibrium has not been fully established.

Studies on Utilization Survey and Forage Quality of Phragmites communis and Miscanthus sinensis as Native Grasses in Paju and Ansan District, 2010 (2010 파주, 안산지역 갈대, 억새 등 야초류의 이용실태와 사료가치 평가)

  • Seo, Sung;Kim, Won-Ho;Jung, Min-Woong;Park, Hyung-Soo;Shim, Jae-Jin;Park, Jin-Gil;Sung, Ha-Guyn;Kim, Jong-Duk;Lee, Joung-Kyong
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.31 no.2
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    • pp.151-158
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    • 2011
  • This study was carried out in 2010 to investigate the utilization and nutritive value of native grasses, such as Phragmites communis and Miscanthus sinensis which might reduce the cost of feeding domestic cattle. The regions within the Civilian Control Line in Paju and Sihwa region in Ansan were surveyed. In Paju, the yearly silage production was 900 MT harvested from 90 ha (10 MT/ha). About 30~50% of these were sold out at the marketing price of 52,000~55,000 Won per roll (130~137.5 Won/kg). Regrown Miscanthus sinensis of 70 cm in length contained 9.6% of crude protein (CP), 82.4 of relative feed value (RFV), and 67.7% of in vitro dry matter digestibility (IVDMD). Regrown Phragmites communis of 70 cm in length contained 13.8% of CP, 84.3 of RFV, and 67.9% of IVDMD. As harvesting was delayed, the quality was decreased dramatically. In Ansan region, Phragmites communis plantation covers 100 ha. The silage production was 550 MT from the area of 50 ha (11 MT/ha) in 2009. And the marketing price was 50,000 Won per roll. But in 2010 only a small amount of grasses could have been baled due to frequent and much rainfall from spring to summer season. However, the good forage quality was observed from regrown Phragmites communis of 80 cm in length, 12.9% CP, 99.8 RFV and 66.6% IVDMD, while that of late matured grasses was very low, 2.2% CP, 52.9 RFV and 36.4% IVDMD, greatly lower than forage quality of rice straw. The quality of grasses at bloom stage of 150 cm in length was similar to that of rice straw, showing 4.5% CP, 59.9 RFV and 42.2% IVDMD. In conclusion, the overall quality of most native grasses in this survey were very poor. Therefore, we recommend that Phragmites communis and Miscanthus sinensis should be harvested during June or July to obtain better forage quality which is richer in forage values than rice straw. Production of high quality forage crops was also desirable for self sufficiency of forage.

Physiological Activity of Sarcodon aspratus Extracts (능이버섯(Sarcodon aspratus) 추출물의 생리활성)

  • 송재환;이현숙;황진국;한정환;노정근;금동혁;박기문
    • Food Science of Animal Resources
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    • v.23 no.2
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    • pp.172-179
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    • 2003
  • This study was carried out to find the preventive medical and therapeutic effects of Sarcodon asparatus on adult disease by employing several biological and biochemical assays. Nitrate scavenging ability(NSA) of Sarcodan asparatus extracts was displayed up to 99.9% at pH 1.2 in a dose-dependent manner. They also had 90.4% electron donating ability(EDA) at the concentration of 0.1 mg/mL. Extracts of Sarcodon asparatus were also able to function as a powerful antioxidant at all concentrations(0.01∼l.0 mg/mL). Furthermore, we observed that 1 mg/mL concentration of the extracts was more powerful than BHT, With respect to fibrolytic activity, Sarcodon asparatus showed 1,843.8 unit/g, which was higher than streptokinase(1,189 unit/g). The inhibitory effects of the extracts on angiotensin converting enzyme, measured by the normal and pretreatment methods, were 53 and 58%, respectively. We also performed cytotoxicity effect of Sarcodon asparatus extracts on a various cancer cell lines. The growth inhibitory effects of the extracts(5.0 mg/mL) on A549, HeLa, AGS, and SK-Hep-1 cells were 78.9, 55.3, 69.0, and 42.5 %, respectively. Interestingly, Sarcodon asparatusextracts induced mutation on Salmonella typhimurium TA98 and TA100 when Ames test was done.

Antibacterial Activities of Bamboo Sap Against Salmonella Typhimurium and Inhibitory Effects in a Model Food System (죽력의 Salmonella typhimurium 등에 대한 항세균 활성과 Model Food System에서의 생육억제 효과)

  • Chung, Hee-Jong;Ko, Bong-Guk
    • Journal of the Korean Society of Food Culture
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    • v.20 no.6
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    • pp.709-714
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    • 2005
  • Antibacterial activities of the freeze-dried bamboo sap dissolved into the water or 50% ethanol were determined and antimicrobial activity of bamboo sap dissolved into distilled water was most strong with 15 mm of the diameter of inhibiting clear zone against Listeria monocytogenes ATCC 19114 among gram positive bacteria tested, but it did not inhibit Bacillus subtilis ATCC 6633 at all, and the sap was most greatly inhibited the growth of Shigella dysenteriae ATCC 9361 among gram negative bacteria with 15 mm of the diameter of inhibiting clear zone. Bamboo sap dissolved into 50% ethanol most strongly inhibited the growth of L. monocytogenes ATCC 19114 and it also inhibited the growth of B. subtilis ATCC 6633 which did not show any with the sap dissolved into distilled water. The sap dissolved into 50% ethanol was most greatly inhibited the growth of S. dysenteriae ATCC 9361 among gram negative bacteria with 23 mm of the diameter of inhibiting clear zone, and it inhibited Vibrio parahaemolyticus WSDH 22, Vibrio vulnilicus ATCC 29307 and Escherichia coli O157 WSDH 54 with 16 mm of the diameter of inhibiting clear zone. However, Both of the saps dissolved in distilled water and 50% ethanol did not showed any inhibition against the lactic acid bacteria of Lactobacillus plantarum KCTC and Lactobacillus brevis KCTC. Most of the tested bacteria were more sensitive to the sap dissolved in 50% ethanol than the sap dissolved in distilled water. The lowest minimum inhibitory concentration of the bamboo sap dissolved into 50% ethanol was 0.6 mg eq./disc with L. monocytogenes ATCC 19114, but that of the sap dissolved into distilled water was 0.8 mg eq./disc with Staphylococcus epidermides ATCC 12228, S. dysenteriae ATCC 9361, L. monocytogenes ATCC 19114, Salmonella typhimurium WSU 2380 and V. parahaemolyticus WSDH 22. In a model food system of the sterilized chocolate milk, antibacterial activities of the sap dissolved into 50% ethanol were relatively stronger than those of the sap dissolved into distilled water and the activities against the bacteria tested were very similar each other. These result suggested the bamboo sap can be used as a natural food preservative.

Axial wall thickness of zirconia abutment in anterior region (전치부 지르코니아 지대주의 축벽 두께)

  • Moon, Seung-Jin;Heo, Yu-Ri;Lee, Gyeong-Je;Kim, Hee-Jung
    • The Journal of Korean Academy of Prosthodontics
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    • v.53 no.4
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    • pp.345-351
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    • 2015
  • Purpose: The purpose of this study was to evaluate the proper axial thickness of zirconia abutment applied to implant in the anterior region. Materials and methods: Zirconia abutments were prepared at different axial wall thickness by processing pre-sintered zirconia blocks via CAD/CAM to obtain equal specimens. The abutments were each produced with a thickness of 0.5 mm (Group 1), 0.8 mm (Group 2), 1.2 mm (Group 3), or 1.5 mm (Group 4). The implant used in this study was a external connection type one (US, Osstem, Pussan, Korea) product and the zirconia abutment was prepared via replication of a cemented abutment. The crowns were prepared via CAM/CAM with a thickness of 1.5 mm and were cemented to the abutments using $RelyX^{TM}$ UniCem cement. A universal testing machine was used to apply load at 30 degrees and measure fracture strength of the zirconia abutment. Results: Fracture strength of the abutments for Group 1, Group 2, Group 3, and Group 4 were $236.00{\pm}67.55N$, $599.00{\pm}15.80N$, $588.20{\pm}33.18N$, and $97.83{\pm}98.13N$, respectively. Group 1 showed a significantly lower value, as compared to the other groups (independent Mann-Whitney U-test. P<.05). No significant differences were detected among Group 2, Group 3, and Group 4 (independent Mann-Whitney U-test. P>.05). Conclusion: Zirconia abutment requires optimal thickness for fracture resistance. Within the limitation of this study, > 0.8 mm thickness is recommended for zirconia abutment in anterior implants.

Antimutagenic and Cytotoxic Effects of Acer ginnala Max. Bark Extracts (신나무 껍질 추출물의 항돌연변이원성 및 세포독성 효과)

  • Oh Heung-Seok;Cui Cheng-Bi;Choi Hyung-Taek;Kim Soo-Hyun;Jeon Mi-Sun;Ham Seung-Shi
    • Food Science and Preservation
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    • v.11 no.4
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    • pp.550-556
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    • 2004
  • In the present study, we investigated the antimutagenic and cytotoxic effects of Acer ginnala Max. bark extract on S. typhimurium TA98, TA100 and cancer cell lines with Ames test and SRB assay, respectively. They were extracted with methanol and then fractionated using hexane, chloroform, ethyl acetate, butanol, and water to obtain the fractions. The inhibition rate of methanol ($200\;{\mu}g/plate$) of Acer ginnala Max. bark extract in the Salmonella typhimurium TA100 strain showed $83.3\%$ against the mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). In addition, the suppression of methanol extract with same concentration of in the Salmonella typhimurium TA98 and TA100 strains showed $80.3\%\;and\;92.7\%$ inhibition against 3-amino-1,4-dimethyl-5H-pyrido-(4,3-b)indol (Trp-P-1), respectively. The cytotoxicity effects of Acer ginnala Max. bark extract against the cell lines with human lung carcinoma (A549), human gastric carcinoma (AGS), human hepatocellular carcinoma (Hep3B) and human breast adenocarcinoma (MCF-7) were inhibited with the increase of the extract concentration. The treatment of 1.0 mg/mL Acer ginnala Max. bark methanol extract of methanol showed strong cytotoxicities of $77.3\%,\;90.4\%,\;88.9\%,\;and\;83.7\%$ against A549, AGS, Hep3B and MCF-7, respectively.

Screening of immune enhancing activities in medicinal herbs, Compositae (국화과 약용 식물의 면역증진활성 검색)

  • Lee, Mi-Kyoung;Moon, Hyoung-Chol;Lee, Jin-Ha;Kim, Jong-Dai;Yu, Chang-Yeon;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.10 no.1
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    • pp.51-57
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    • 2002
  • The biological activities of immune modulating activities of the extracts from Echinacea purpurea, Chrysanthmum indicum L. and Circium japonicum var. ussuriense KITAMURA were compared. About 70% of the growth of human hepatocarcinoma and 80% of human gastric cancer cell was inhibited in adding 0.5mg/ml of the ethanol extracts of Echinacea purpurea, Chrysanthmum indicum L. and Circium japonicum var. ussuriense KITAMURA, respectively. The growth of human breast cancer cells was also inhibited in adding 0.5mg/ml of the extracts as well as 60% of the human cancer cells. It was proved that the growth of human normal lung cell, scored as 15% for the extracts. Overall selectivity of the extracts on several human cancer cell line was over 3, which is higher than those from the conventional herbs. The growth of both human immune B and T cells was enhanced up to 1.4 to 2.0 times by adding the extracts, compared to the controls. The secretion of tumor necrosis $factor-alpha(TNF-{\alpha})$ from T cell was also increased up to 94 pg/ml in adding the Echinacea purpurea ethanol extract (0.5mg/ml). Circium japonicum var. ethanol extract also increased up to about 96 pg/ml of interleukin-6(IL-6) from B cell.

EXPRESSION OF BMP4, BMP6 FOLLOWING SINUS ELEVATION WITH DBBP IN RABBIT (가토 상악동 점막 거상 후 DBBP를 이식재로 사용시 BMP4, BMP6의 발현)

  • Lee, Hyun-Suk;Heo, Hyun-A;Pyo, Sung-Woon;Lee, Won
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.29 no.6
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    • pp.467-473
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    • 2007
  • The most important factor for successful implantation is osseointegration between the implant and bone. The expression of bone morphogenetic proteins (BMPs) inducing bone formation would differ after maxillary sinus elevation. And within the same graft material. the expression of BMPs would change with time after graft. The aim of this study was to compare the relative expressions of BMP4 and BMP6 using real-time RT-PCR when maxillary sinus elevation was performed using deproteinated bovine bone powder (DBBP) as the graft material or absorbable gelatin sponge (AGS) as the filler without any graft material. Fifteen rabbits, each weighing between 3.0 to 3.5 Kg, were divided randomly into 5 groups of 3 animals each based on their time of sacrifice 0, 3, 5, 7 and 9 days). After exposure of the maxillary sinus bilaterally, bone graft was performed in the right maxillary sinus using DBBP ($BBP^{(R)}$ Oct Inc., Cheonan, Korea) and only AGS ($Gelfoam^{(R)}$ Pharmacia & Upjohn Company, Kalamazoo, MI, U.S.A) was placed into the left without any graft material. Each group of rabbits was sacrificed at 1, 3, 5, 7, or 9 days after operation and all specimens were harvested. And the following results were obtained using real-time RT-PCR from isolated total RNA of the samples. 1. The expression of BMP4 increased at postoperative 1 and 3 days in both DBBP group and AGS group. In AGS group. it decreased at postoperative 5 days. increased again at postoperative 7 days, and decreased at postoperative 9 days. In DBBP group, it increased until postoperative 7 days and decreased at postoperative 9 days. Although the expression of BMP4 was higher in DBBP group compared with AGS group, it was not statistically significant (p>0.05). 2. The expression of BMP6 increased at postoperative 1 and 3 days in both DBBP group and AGS group. In AGS group, it decreased at postoperative 5 days, increased again at postoperative 7 days, and decreased at postoperative 9 days. In DBBP group, it increased until postoperative 7 days and decreased at postoperative 9 days. Although the expression of BMP6 was higher in AGS group compared with DBBP group, it was not statistically significant (p>0.05). 3. There was no statistically significant difference in BMP expression in both groups during same period of time. It' s probably because DBBP and AGS both functioned as a space retainer so that the BMP expression in blood clot seemed to be similar. 4. Thus, DBBP would not offer many benefits for early bone regeneration compared with AGS. The expression of BMP in early bone formation seems to be more influenced by physical carrier rather than the graft type.