• Annals of Clinical Neurophysiology
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• v.18 no.1
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• pp.18-20
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• 2016

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that clinically manifests both upper and lower motor neuron signs. However, it is unknown where and how the motor neuron degeneration begins, and conflicting hypotheses have been suggested. Recent advanced radiological techniques enable us to look into ALS neuropathology in vivo. Herein, we report a case with upper motor neuron-predominant ALS in whom the results of brain magnetic resonance imaging (MRI) and myelin water fraction MRI suggest axonal degeneration.

• Mass Spectrometry Letters
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• v.10 no.3
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• pp.71-78
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• 2019

For several decades, cancer has been the primary cause of mortality worldwide. New diagnosis and regimens have been developed to improve the chemotherapeutic efficacy and the quality of life of the patients. However, cancer tissues are complex and difficult to assess. Understanding the various properties of the tumor and its environment is crucial for cancer and pharmaceutical research. Several analytical techniques have been providing new insights into cancer research. Recently, matrix-assisted laser desorption ionization (MALDI)-mass spectrometry imaging (MSI), an advanced analytical technique, has been applied to translational research. Proteomic and lipidomic profiling obtained by MALDI-MSI has been critical for biomarker discovery and for monitoring heterogenous tumor tissues. In this review, we discuss technical approaches, benefits and recent applications of MALDI-MSI as a valuable tool in cancer research, namely for diagnosis, therapy, prognosis.

• Korean Journal of Radiology
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• v.24 no.11
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• pp.1114-1130
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• 2023

Magnetic resonance neurography (MRN) is increasingly used to visualize peripheral nerves in vivo. However, the implementation and interpretation of MRN in the brachial and lumbosacral plexi are challenging because of the anatomical complexity and technical limitations. The purpose of this article was to review the clinical context of MRN, describe advanced magnetic resonance (MR) techniques for plexus imaging, and list the general categories of utility of MRN with pertinent imaging examples. The selection and optimization of MR sequences are centered on the homogeneous suppression of fat and blood vessels while enhancing the visibility of the plexus and its branches. Standard 2D fast spin-echo sequences are essential to assess morphology and signal intensity of nerves. Moreover, nerve-selective 3D isotropic images allow improved visualization of nerves and multiplanar reconstruction along their course. Diffusion-weighted and diffusion-tensor images offer microscopic and functional insights into peripheral nerves. The interpretation of MRN in the brachial and lumbosacral plexi should be based on a thorough understanding of their anatomy and pathophysiology. Anatomical landmarks assist in identifying brachial and lumbosacral plexus components of interest. Thus, understanding the varying patterns of nerve abnormalities facilitates the interpretation of aberrant findings.

• Investigative Magnetic Resonance Imaging
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• v.12 no.2
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• pp.89-99
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• 2008

Imaging assessment of prostate cancer is one of the most difficult sections of oncology imaging. Detecting, localizing and staging of the primary prostate cancer by preoperative imaging are still challenging for the radiologist. Magnetic resonance (MR) imaging provides excellent soft tissue contrast and is widely used for solid organ imaging, but results of preoperative imaging of the prostate gland with conventional MR imaging is unsatisfactory. Positron emission tomography and computed tomography (PET/CT) is the cornerstone in oncology imaging, but some limitations prohibit the assessment of primary prostate cancer with PET or PET/CT. Recent studies to overcome these insufficient accuracies of imaging evaluation of primary prostate cancers with advanced MR techniques and PET and PET/CT are reported. In this article, we review the imaging findings of prostate cancer on variable modalities, focused on MR imaging and PET/CT.

• Journal of the Korea Convergence Society
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• v.12 no.11
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• pp.207-220
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• 2021

Recent advances in new media for sensory experiences keep expanding visual expression methods in installation art such as projection mapping and virtual reality. Artists can create and develop visual expression techniques based on such new media. Projection mapping is a new medium that continues to add various possibilities to visual expression in media art. Under the projection mapping environment, artists can recompose the object or space with the digital content by projecting video onto three-dimensional surfaces in the space. This paper focuses on the process where visual expression with the projection mapping technology leads to viewers' sensory experience. To this end, "reproducibility," "dissemination," "virtuality," and "interactivity" of media were analyzed to describe the meaning and *definition of visual expression. Artworks are considered as an example to study visual expression techniques such as "repetition and overlap," "simulacrum and metaphor," and "displacement and conversion." I applied the analysis and created Domino, a projection mapping artwork, which helps the research on visual expression techniques that can lead to sensory experience the extensibility of visual expression.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.2
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• pp.55-68
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• 2014

Some infrastructure these days is usually constructed under the ground for it to not interfere the foot-traffic of pedestrians, and thus, it is difficult to visually confirm the accurate location of the site where the establishments must be buried. These technical difficulties increase the magnitude of the problems that could arise from over-reliance on the experience of the worker or a mere blueprint. Such problems include exposure to flood and collapse. This paper proposes a constructor-oriented visualization system via mobile gadgets in general construction sites with occluded structures. This proposal is consisted with three stages. First, "Stage of detecting manhole and extracting features" detects and extracts the basis point of occluded structures which is unoccluded manhole. Next, "Stage of tracking features" tracks down the extracted features in the previous stage. Lastly, "Stage of visualizing occluded constructions" analyzes and synthesizes the GPS data and 3D objects obtained from mobile gadgets in the previous stages. This proposal implemented ideal method through parallel analysis of manhole detection, feature extraction, and tracking techniques in indoor environment, and confirmed the possibility through occluded water-pipe augmentation in real environment. Also, it offers a practical constructor-oriented environment derived from the augmented 3D results of occluded water-pipings.

• Physical Therapy Korea
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• v.22 no.2
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• pp.70-80
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• 2015

The spinal cord is highly complex, consisting of a specialized neural network that comprised both neuronal and non-neuronal cells. Any kind of injury and/or insult to the spinal cord leads to a series of damaging events resulting in motor and/or sensory deficits below the level of injury. As a result, muscle paralysis (or paresis) leading to muscle atrophy or shrinking of the muscle along with changes in muscle fiber type, and contractile properties have been observed. Traditionally, histology had been used as a gold standard to characterize spinal cord injury (SCI)-induced adaptation in spinal cord and skeletal muscle. However, histology measurements is invasive and cannot be used for longitudinal analysis. Therefore, the use of conventional magnetic resonance imaging (MRI) is promoted to be used as an alternative non-invasive method, which allows the repeated measurements over time and secures the safety against radiation by using radiofrequency pulse. Currently, many of pathological changes and adaptations occurring after SCI can be measured by MRI methods, specifically 3-dimensional MRI with the advanced diffusion tensor imaging technique. Both techniques have shown to be sensitive in measuring morphological and structural changes in skeletal muscle and the spinal cord.

• Investigative Magnetic Resonance Imaging
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• v.26 no.2
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• pp.83-95
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• 2022

The purpose of this study was to establish and provide guidelines for the standardized acquisition and interpretation of diffusion-weighted magnetic resonance imaging (DW-MRI) to improve the image quality and reduce the variability of the results interpretation. The standardized protocol includes the use of high-resolution DW-MRI with advanced techniques and post-processing. The aim of the protocol is to increase the effectiveness of the medical image information exchange involved in the construction, activation, and exchange of clinical information for healthcare use. An organized interpretation form could make DW-MRIs' interpretation easier and more familiar. Herein, the authors briefly review the basic principles, optimized image acquisition, standardized interpretation guidelines, false negative and false positive cases of DW-MRI, and provide a standard interpretation form and examples of various cases to help users become more familiar with the DW-MRI.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.6
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• pp.63-74
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• 2007

Fast Fourier transform(FFT) is powerful, fast computation framework for convolution in many image restoration application. However, an actually observed image acquired with finite aperture of the acquisition device from the infinite background and it lost data outside the cropped region. Because of these the boundary artifacts are produced. This paper reviewed and summarized the up to date the techniques that have been applied to reduce of the boundary artifacts. Moreover, we propose a new block-based fast image restoration using combined extrapolation and edge-tapering without boundary artifacts with reduced computational loads. We apply edgetapering to the inner blocks because they contain outside information of boundary. And outer blocks use half-convolution extrapolation. For this process it is possible that fast image restoration without boundary artifacts.

• Progress in Medical Physics
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• v.32 no.2
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• pp.25-39
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• 2021

Brachytherapy, along with external beam radiation therapy (EBRT), is an essential and effective radiation treatment process. In brachytherapy, in contrast to EBRT, the radiation source is radioisotopes. Because these isotopes can be positioned inside or near the tumor, it is possible to protect other organs around the tumor while delivering an extremely high-dose of treatment to the tumor. Brachytherapy has a long history of more than 100 years. In the early 1900s, the radioisotopes used for brachytherapy were only radium or radon isotopes extracted from nature. Over time, however, various radioisotopes have been artificially produced. As radioisotopes have high radioactivity and miniature size, the application of brachytherapy has expanded to high-dose-rate brachytherapy. Recently, advanced treatment techniques used in EBRT, such as image guidance and intensity modulation techniques, have been applied to brachytherapy. Three-dimensional images, such as ultrasound, computed tomography, magnetic resonance imaging, and positron emission tomography are used for accurate delineation of treatment targets and normal organs. Intensity-modulated brachytherapy is anticipated to be performed in the near future, and it is anticipated that the treatment outcomes of applicable cancers will be greatly improved by this treatment's excellent dose delivery characteristics.