• Journal of Trauma and Injury
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• v.37 no.2
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• pp.166-169
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• 2024

Stab wounds, particularly those affecting multiple body regions, present considerable challenges in trauma care. This report describes a case of sustained self-inflicted stab injuries to the abdomen and thighs of a 23-year-old male patient. Although the patient's vital signs were stable and bleeding was minimal from thigh wounds without overt signs of vascular injury, the patient experienced a sudden, profound hemorrhage from the right thigh, leading to cardiac arrest. Successful resuscitation was followed by surgical repair of a right superficial femoral arterial injury accompanying a resuscitative endovascular balloon of the aorta. Subsequent lower extremity computed tomography angiography revealed no additional vascular abnormalities. The patient was discharged in stable condition on the 12th postoperative day. This case underscores the unpredictability of stab wound trajectories and the potential for hidden vascular injuries, even in the absence of immediate life-threatening signs. It also emphasizes the critical role of advanced imaging modalities, such as computed tomography angiography, in identifying concealed injuries, and the importance of strategic intraoperative techniques, including resuscitative endovascular balloon occlusion of the aorta, in achieving favorable patient outcomes.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.1
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• pp.15-29
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• 2024

A fetoscope is an optical endoscope, which is often applied in fetoscopic laser photocoagulation to treat twin-to-twin transfusion syndrome. In an operation, the clinician needs to observe the abnormal placental vessels through the endoscope, so as to guide the operation. However, low-quality imaging and narrow field of view of the fetoscope increase the difficulty of the operation. Introducing an accurate placental vessel segmentation of fetoscopic images can assist the fetoscopic laser photocoagulation and help identify the abnormal vessels. This study proposes a method to solve the above problems. A novel encoder-decoder network with a dual-path structure is proposed to segment the placental vessels in fetoscopic images. In particular, we introduce a channel attention mechanism and a continuous convolution structure to obtain multi-scale features with their weights. Moreover, a switching connection is inserted between the corresponding blocks of the two paths to strengthen their relationship. According to the results of a set of blood vessel segmentation experiments conducted on a public fetoscopic image dataset, our method has achieved higher scores than the current mainstream segmentation methods, raising the dice similarity coefficient, intersection over union, and pixel accuracy by 5.80%, 8.39% and 0.62%, respectively.

• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.27 no.1
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• pp.114-119
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• 2023

A 51-year-old male patient had four times of massive hematochezia episode three days before arrival. Carbohydrate antigen (CA) 19-9 level was extremely elevated. Computed tomography, magnetic resonance imaging, and positron emission tomography-computed tomography identified 5.7 cm sized periampullary duodenal cancer with regional metastatic lymph nodes and vascular invasion to aberrant right hepatic artery, main portal vein, and superior mesenteric vein. Diagnosed as duodenal adenocarcinoma through endoscopic biopsy, 16 times of FOLFIRI (5-fluorouracil, leucovorin, irinotecan) was conducted. The regimen changed to XELOX (capecitabine, oxaliplatine), four times of administration was done, and the CA19-9 level dramatically decreased. The tumor decreased to 2.1 cm. After R0 laparoscopic pylorus preserving pancreatoduodenectomy, no adjuvant therapy was given. No sign of recurrence or metastasis was reported, and the patient reached complete remission after five years. We reported a case where neoadjuvant chemotherapy for locally advanced duodenal adenocarcinoma was shown to be effective.

• BMB Reports
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• v.57 no.3
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• pp.155-160
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• 2024

Lung cancer carries one of the highest mortality rates among all cancers. It is often diagnosed at more advanced stages with limited treatment options compared to other malignancies. This study focuses on calnexin as a potential biomarker for diagnosis and treatment of lung cancer. Calnexin, a molecular chaperone integral to N-linked glycoprotein synthesis, has shown some associations with cancer. However, targeted therapeutic or diagnostic methods using calnexin have been proposed. Through 1D-LCMSMS, we identified calnexin as a biomarker for lung cancer and substantiated its expression in human lung cancer cell membranes using Western blotting, flow cytometry, and immunocytochemistry. Anti-calnexin antibodies exhibited complement-dependent cytotoxicity to lung cancer cell lines, resulting in a notable reduction in tumor growth in a subcutaneous xenograft model. Additionally, we verified the feasibility of labeling tumors through in vivo imaging using antibodies against calnexin. Furthermore, exosomal detection of calnexin suggested the potential utility of liquid biopsy for diagnostic purposes. In conclusion, this study establishes calnexin as a promising target for antibody-based lung cancer diagnosis and therapy, unlocking novel avenues for early detection and treatment.

• Electronics and Telecommunications Trends
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• v.39 no.4
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• pp.54-62
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• 2024

The emergence and resurgence of novel respiratory infectious diseases since the turn of the millennium, including SARS, H1N1 flu, MERS, and COVID-19, have posed a significant global health threat. Efforts to combat these threats have involved various approaches, however, continued research and development are crucial to prepare for the possibility of emerging viruses and viral variants. Direct detection methods for viral pathogens include molecular diagnostic techniques and immunodiagnostic methods, while indirect diagnostic methods involve detecting changes in the condition of infected patients through imaging diagnostics, gas analysis, and biosignal measurement. Molecular diagnostic techniques, utilizing advanced technologies such as gene editing, are being developed to enable faster detection than traditional PCR methods, and research is underway to improve the efficiency of diagnostic devices. Diagnostic technologies for infectious diseases continue to evolve, and several key trends are expected to emerge in the future. Automation will facilitate widespread adoption of rapid and accurate diagnostics, portable diagnostic devices will enable immediate on-site diagnosis by healthcare professionals, and advancements in AI-based deep learning diagnostic models will enhance diagnostic accuracy.

• The Korean Journal of Nuclear Medicine
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• v.30 no.1
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• pp.56-64
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• 1996

The purpose of this study was to evaluate the characteristic perfusion changes in patients with Sturge-Weber syndrome by comparison of the findings of brain MR images and perfusion SPECT images. $^{99m}Tc$-HMPAO or $^{99m}Tc$-ECD interictal brain SPECTs were performed on 5 pediatric patients with Sturge-Weber syndrome within 2 weeks after MR imaging. Brain SPECTs of three patients without calcification showed diminished perfusion in the affected area on MR image. A 3 month-old patient without brain atrophy or calcification demonstrated paradoxical hyperperfusion in the affected hemisphere, and follow-up perfusion SPECT revealed decreased perfusion in the same area. The other patient with advanced calcified lesion and atrophy on MR image showed diffusely decreased perfusion in the affected hemisphere, but a focal area of increased perfusion was also noted in the ipsilateral temporal lobe on SPECT. In conclusion, brain perfusion of the affected area of Sturge-Weber syndrome patients was usually diminished, but early or advanced patients may show paradoxical diffuse or focal hyperperfusion in the affected hemisphere. Further studies are needed for better understanding of these perfusion changes and pathophysiology of Sturge-Weber syndrome.

• Journal of Astronomy and Space Sciences
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• v.22 no.4
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• pp.441-450
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• 2005

The organic material is one of the most popular material for the satellites and the spacecrafts in order to perform the thermal management, and to protect direct exposure from the space environment. The present paper observes material property changes of organic material under the space environment by using ground facilities. One of the representative organic thermal management material of satellites, 2 mil ITO(Indium Tin Oxide) coated aluminized KAPTON was selected for experiments. In order to investigate the single parametric effect of protons in space environment, MC-50 cyclotron system in KIRAMS(Korea Institute of Radiological and Medical Science) was utilized for the ion beam irradiation of protons and ion beam dose was set to the Very Large August 1972 EVENT model, the highest protons occurrence near the earth orbit in history. The energy of ion beam is fixed to 30MeV(mesa electron volt), observed average energy, and the equivalent irradiance time conditions were set to 1-year, 3-year, 5-year and 10-year exposure in space. The procedure of analyses includes the measurement of the ultimate tensile strength for the assessment of quantitative degradation in material properties, and the imaging analyses of crystalline transformation and damages on the exposed surface by FE-SEM(Field Emission Scanning Electron Spectroscopy) etc.

• Korean Journal of Remote Sensing
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• v.32 no.6
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• pp.579-587
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• 2016

To obtain a stable energy supply and manage PhotoVoltaic (PV) systems efficiently, satellite imagery methods are being developed to estimate the solar PV potential. This study analyzed trends in the use of satellite imagery in solar PV and solar irradiation estimation technology. The imaging technology is used to produce solar energy resource maps. The trend analysis showed that the level of solar PV technology in Korea is 30% below that of advanced countries. It is impossible to raise such low-level technologies to the levels of advanced countries quickly. Intensive research and development is the only way to achieve the 80% technology level of advanced countries. The information produced in this process can contribute to the management of solar power plants. A valid technology development strategy would be to obtain effective data that can be used for fieldwork. Such data can be produced by estimating solar irradiation very accurately with several-hundred-meter resolution using Communication, Ocean, and Meteorological Satellites (COMS) and next-generation GEO-KOMPSAT 2A, developing core technologies for short- and medium-term irradiation prediction, and developing technologies for estimating the solar PV potential.

• Applied Microscopy
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• v.34 no.1
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• pp.13-21
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• 2004

The high voltage electron microscope (HVEM) newly installed in KBSI is an advanced transmission electron microscope capable of atomic resolution (${\leq}1.2{\AA}$ point-to-point resolution) together with high titling function (${\pm}60^{\circ}$), which are suitable to do 3-dimensional atomic imaging of a specimen. In addition, the instrument can be controlled by remote operation system, named as 'FasTEM' for the HVEM, which is favorable to overcome some environmental obstacles resulting from the direct operation. The FasTEM remote operation system has been established between the headquarter of KBSI in Daejeon and the Seoul branch. The server system in the headquarter has been connected with a portable client console system in the Seoul branch using an advanced internet resource, 'KOREN' of 155 Mbps grade. Most of the HVEM functions essential to do remote operation are available on the portable client console. The experiment to acquire the high resolution image of [001] Au has been achieved by excellent transmission of control signals and communication with the HVEM. Real-time reaction like direct operation, such as controls of the illumination and projection parameters, acquisition and adjustment of each detector signal, and electrical steering of each motor-driven system has been realized in remote site. It is positively anticipated that the first remote operation of HVEM in conjunction with IT infraengineering plays a important role in constructing the network based e-Science Grid in Korea for national user s facilities.

• Geophysics and Geophysical Exploration
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• v.25 no.3
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• pp.129-139
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• 2022

Analog-based streamers for ultra-high-resolution seismic surveys are capable of additional noise ingress in water, but the specifications cannot be expanded through interconnections. Foreign-produced digital streamers have been introduced and used primarily at domestic research institutes; however, the cost is high and smooth maintenance is challenging. This study investigates the localization of ultra-high-resolution digital streamers capable of high-resolution imaging of a geological structure. A digital streamer capable of 24-bit, 10 kHz digital sampling of up to 64 channel data was developed through research and development. Various quantitative specifications of the system were designed and developed close to the benchmark model, Geometrics' GeoEel streamer, and the number of modules that make up the system was drastically reduced, reducing development costs and making it easier to use. The field applicability of the developed streamer system was evaluated in an in situ experiment conducted in the waters around the Port of Yeong-il Bay in Pohang in April 2022.