• 제목/요약/키워드: Administration rate

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흰쥐에서 Tiletamine-Zolazepam 및 Lidocaine의 경막외투여시의 마취 효과 (The Anesthetic Effects of the Epidural Administration of Tiletamin-Zolazepam and Lidocaine in Rats)

  • 윤영탁;김명철;이내경;김민규
    • 한국임상수의학회지
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    • 제16권1호
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    • pp.69-74
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    • 1999
  • This study was performed to evaluate the anesthetic effects of the epidural administration of tiletamin-zolazepam and lidocaine to rats. Blood pressure, heart rate, respiratoty rate and blood chemistry were examined according to the time lapse, after the administration of tiletamine-zolazepam, lidocaine or saline. The results obtained were as follows. 1, Tiletamine-zolazepam group revealed fast anesthesia onset time (p<0.01) and also revealed prolonged ambulation time compared with lidocaine group (p<0.01). 2. In the effects of blood pressure, tiletamine-zolazepam group revealed significantly higher value than lidocaine group or saline group, and revealed the highest value at 20 minutes after administration. According to the time lapse, blood pressure of tiletamine-zolazepam group was recovered and showed similar value with lidocaine group and control group at 90 minutes after administration. 3. In the effects of heart rate, tiletamine-zolazepam group revealed significantly lower value than lidocaine group or saline group and revealed the lowest value at 30 minutes after administration, and recovered similar value with pre-administration at 90 minutes after administration. 4. In the effects of respiratory rate, lidocaine group revealed significantly lower value at 30 minutes administration compared with 0 and 60 minutes after administration (p<0.01). Tiletamine-zolazepam group also revealed significantly lower value at 30 minutes compared with 0 and 60 minutes after administration (p<0.01). The changes at 60 minutes after administration, lidocaine group revealed lower value than saline or tiletamine-zolazepam group, and tiletamine-zolazepam group revealed similar value with 0 minutes. 5. In the effects of tidal volume, lidocaine group revealed significantly lower value than saline group (p<0.001) and tiletamine-zolazepam group also revealed lower value than saline group, at 30 minutes after administration. The values at 60 minutes after administration, revealed similar results with that of 30 minutes after administration. 6. In the blood chemistry, the values of alanine transminase (ALT), aspartate transminase(AST) and creatinine did not reveal significant results at 60 minutes after administration. The values of ALT at 60 minutes slightly decreased compared with pre-administration, and revealed normal level.

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항염 및 해열효과에 미치는 Ibuprofen과 Prednisolone의 약 상호 작용 (Drug Interactions of Ibuprofen and Prednisolone in Antiinflammatory and Antipyretic Effects)

  • 강영자;조윤성
    • 약학회지
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    • 제25권3호
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    • pp.109-114
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    • 1981
  • The authors investigated drug interaction of ibuprofen and prednisolone in antiinflammatory and antipyretic activities. We have found significant differences of the antiinflammatory and antipyretic activities between single and concurrent administration of ibuprofen and prednisolone, using Sprague-Dawley Strain rats, carrageenin as a phlogistic agent and brewer's yeast as a fever inducing agent. 1) Ibuprofen(20mg/kg) was administered to the rats orally and resulted in significant reduction of (31.70 %) the swelling of rat paw induced by carrageenin, 2) prednisolone (9mg/kg) showed significant reduction of (45.76%) the swelling, 3) concurrent administration of ibuprofen (20mg/kg) and prednisolone (9mg/kg) also reduced (57.40%) the swelling. In ibuprofen (125mg/kg) administration, the inhibition rate of edema was 39.32% and in prednisolone (1mg/kg) administration, the rate was 39.04%. In concurrent administration of ibuprofen (125mg/kg) and prednisolone (1mg/kg), the inhibition rate of edema was 63.09%. Concurrent administration of ibuprofen and prednisolone showed more anti-inflammatory effects than single administration of ibuprofen and prednisolone respectively. Prednisolone itself did not show antipyretic effect, but concurrent administration of ibuprofen and prednisolone showed more antipyretic effects than ibuprofen single administratron.

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Method for Analysis on Optimization of Averaging Interval of Rainfall Rate Measured by Tipping-Bucket Rain Gauges

  • Nam, Kyung-Yeub;Chang, Ki-Ho;Kim, Kyung-Eak;Oh, Sung-Nam;Choi, Young-Jean;Kim, Kyung-Sik;Lee, Dong-In;Kim, Kum-Lan
    • 대한원격탐사학회지
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    • 제24권1호
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    • pp.17-24
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    • 2008
  • Rainfall data from three different types of rain gauge system have been collected for the summertime rain event at Mokpo in the Korean peninsula. The rain gauge system considered in this paper is composed of three tipping-bucket rain gauges with 0.1, 0.2, and 0.5 mm measuring resolutions, the Optical Rain Gauge (ORG), and the PARSIVEL (PARticle SIze and VELocity). The PARSIVEL rainfall rate has been considered as the reference for comparison since it gave good resolution and performance on this event. Comparison with the PARSIVEL rainfall rate gives the results that the error and temporal variation of rainfall rate are simultaneously reduced with increasing the averaging interval of rainfall rate or decreasing the size of tipping bucket. This suggests that the estimated rainfall rate must be optimized, differently for the type of tipping-bucket rain gages, by minimizing the averaging interval of rainfall rate under the condition satisfying the given performance of rainfall rate.

Pregnancy rate in Hanwoo cows after timed artificial insemination using different sperm concentrations

  • Sung-Sik Kang;Sang-Rae Cho;Ui-Hyung Kim;Yonghwan Kim;Seok-Dong Lee;Myung-Suk Lee;Eunju Kim;Jeong-Il Won;Shil Jin;Hyoun-Ju Kim;Sungwoo Kim;Sun-Sik Jang;Seunghoon Lee
    • 한국동물생명공학회지
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    • 제39권1호
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    • pp.40-47
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    • 2024
  • Background: Sperm quality and the number of sperm introduced into the uterus during artificial insemination (AI) are pivotal factors influencing pregnancy outcomes. However, there have been no reports on the relationship between sperm concentration at AI and sperm quality in Hanwoo cattle. In this study, we examined sperm quality and pregnancy rates after AI using sperm inseminated at different concentrations. Methods: We evaluated the motility, viability, and acrosomal membrane integrity of sperm at different concentrations (10, 15, 18, and 20 million sperm/straw) in 0.5-mL straws. Subsequently, we compared the pregnancy rates after AI with different sperm concentrations. Results: After freeze-thawing, sperm at the assessed concentrations showed similar viability and acrosomal membrane integrity. After AI, cattle in the 10 million group had significantly lower pregnancy rates compared to those in the 18 and 20 million groups. Conversely, there were no statistically significant variances observed between cattle in the 10 and 15 million groups. Conclusions: Sperm at concentrations of 10, 15, 18 and 20 million per straw exhibited comparable motility, viability, and acrosomal membrane integrity. However, a concentration of at least 18 million sperm per straw is required to achieve a consistent rate of pregnancy rate in Hanwoo cattle after AI.

Synnemata Production Using Silkworm Variety, Female Yangwonjam by Isaria tenuipes

  • Ji, Sang-Duk;Sung, Gyoo-Byung;Kang, Pil-Don;Kim, Kee-Young;Choi, Yong-Soo;Kim, Nam-Suk;Woo, Soon-Ok;Han, Sang-Mi;Hong, In-Pyo;Ha, Nam-Gyu
    • Mycobiology
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    • 제39권3호
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    • pp.158-163
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    • 2011
  • This study was conducted to confirm the possible use of female Yangwonjam as a host for synnemata production of Isaria tenuipes in eight local areas in Korea. Silkworm pupation rate, infection rate and synnemata characteristics of I. tenuipes were examined. Normal silkworms had a higher pupation rate than silkworms inoculated with I. tenuipes. The pupae survival percentage of normal silkworm in cocoons was 92.5~97.6%, whereas it ranged from 91.1~95.6% in silkworms sprayed with I. tenuipes. Female Yangwonjam showed the highest survival percentage at 97.6% among the silkworm varieties tested. I. tenuipes infection rate of larvae of 5th instar newly-exuviated silkworms was 89.2~90.7% in the spring rearing season and 98.2~99.3% in the autumn rearing season. Synnemata production of I. tenuipes was excellent in female Yangwonjam with an incidence rate of 98.0% followed by male Yangwonjam (94.1%) and Baegokjam (93.3%) in the spring rearing season. Synnemata living weight ranged from 1.44~0.94 g in the spring rearing season. The female Yangwonjam had the heaviest synnemata weight (1.44 g) in the spring rearing season. The synnemata of I. tenuipes produced on pupae were white or milky-white in color, and were similar in shape and color to wild synnemata collected in Korea.

건강보험 본인일부부담률 적정성에 대한 대중의 인식 (Public Perception on Coinsurance Rate of the National Health Insurance in Korea)

  • 조하현;김지은;함명일;강은정;김선정
    • 보건행정학회지
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    • 제30권4호
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    • pp.451-459
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    • 2020
  • Background: Although Korean government have been adopting several policies to expand coverage of National Health Insurance (NHI) program, the coverage rate is still below average across Organization for Economic Cooperation and Development countries. This study was to identify public perception on appropriateness of coinsurance rate and factors associated with coinsurance rate in National Health Insurance. Methods: For this cross-sectional study, 507 participants over aged 20 years were recruited from telephone surveys. Respondents experienced at least one and more visiting medical facilities due to medical problems in last 12 months. Demographic factors, socioeconomic positions, and experiences on medical utilization were measured in order to identify factors associated with perception appropriateness of coinsurance rate. Results: The 49.9% (n=209) of the public responded that the coinsurance rate of NHI program was appropriate. There were no differences in positive perception according to socio-demographic factors and experiences on medical utilization except for gender, residential area, and felt expensive when using medical services. People who felt burden of medical expenditure were more likely to perceive coinsurance rate inappropriate (odds ratio, 2.33; 95% confidence interval, 1.52-3.58) Conclusion: In spite of the relatively low coverage rate of NHI, this study identified that 49.9% of the public perceived the current coinsurance rate was adequate. However, people who felt the burden of medical expenditure were still had a negative perception of the coinsurance rate needed to decrease the coinsurance rate.

소식재배용 이앙기 모판 이송간격에 따른 이앙정확도 분석 (Analysis of Transplanting Accuracy of Rice Transplanter for Low density Planting According to Transfer Distance to Seedling Tray)

  • 김원경;이상희;최덕규;박석호;강연구;문석표;천창욱;장성혁
    • 드라이브 ㆍ 컨트롤
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    • 제21권2호
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    • pp.30-35
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    • 2024
  • Domestic rice is more expensive than imported products, so it is necessary to reduce production costs to secure competitiveness. Low-density planting developed in Japan is a cultivation technology that reduces labor and production costs without yield loss. The area of low-density cultivation is continuously increasing. However, research on how rice transplanters adapt to low-density planting has not been conducted. Therefore, this study was carried out to determine the optimal working conditions of a rice transplanter for low-density planting. Three types of rice transplanters were used and treated based on 3 conveying distance levels. The number of picked seedlings, pick missing rate, the number of planted seedlings, and the mis-planted rate were investigated to evaluate planting accuracy according to the transfer distance to the seedling tray. The results showed that the number of planted seedlings was 4.31~4.95 EA with an L1 seedling tray transfer distance (horizontal 9 mm, vertical 8 mm), but the mis-planted rate was higher than in other conditions. At L2 (horizontal 9 mm, vertical 10 mm) and L3 (horizontal 11 mm, vertical 8 mm) transfer distance conditions, the number of planted seedlings were 4.89-5.68 EA and 4.69-5.66 EA, respectively, with a low mis-planted rate of less than 3%. The results showed that if the transfer distance is adjusted properly, a rice transplanter can be used for low-density planting with high planting accuracy.

Association of Duration and Rate of Grain Filling with Grain Yield in Temperate Japonica Rice (Oryza sativa L.)

  • Yang, Woon-Ho;Park, Tae-Shik;Kwak, Kang-Su;Choi, Kyung-Jin;Oh, Min-Hyuk
    • 한국작물학회지
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    • 제52권1호
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    • pp.112-121
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    • 2007
  • Grain filling is a crucial factor that determines grain yield in crops since it is the final process directly associated with crops' yield performance. Grain filling process can be characterized by the interaction of rate and duration of grain filling. This study was conducted, using 16 temperate japonica rice genotypes, with aims to (1) seek variations in grain filling duration and rate on area basis, (2) compare the contribution of grain filling duration and rate to grain yield, and (3) examine the influence of temperature and solar radiation for effective grain filling on grain yield in relation to grain filling duration and rate. Grain filling rate and duration exhibited highly significant variations in the ranges of $20.7{\sim}46.3\;g\;m^{-2}d^{-1}\;and\;11.2{\sim}35.5$ days, respectively, depending on rice genotypes. Grain yield on unit area basis was associated positively with grain filling duration but negatively with grain filling rate. Grain filling rate and duration were negatively correlated with each other. Final grain weight increased linearly with the rise in both cumulative mean temperature and cumulative solar radiation for effective grain filling. Higher cumulative mean temperature and cumulative solar radiation for effective grain filling were the results of longer grain filling duration, but not necessarily higher daily mean temperature and daily solar radiation for effective grain filling. Grain filling rate demonstrated an increasing tendency with the rise in daily mean temperature for effective grain filling but their relationship was not obviously clear. It was concluded that grain filling duration, which influenced cumulative mean temperature and cumulative solar radiation for effective grain filling, was the main factor that determined grain yield on unit area basis in temperate Japonica rice.

The Change of Arabinoxylan, Phytic Acid and Vitamin E Contents Whole Wheat Flour depends on the Millig Rate Milling Rate in the Korean Wheat Cultivar 'Saekuemkang'

  • Go Eun Lee;Kyeong-Hoon Kim;Jinhee Park;Kyeong-Min Kim;Chang-Hyun Choi;Mina Kim ;Myoung Hui Lee;Chon-Sik Kang;Jiyoung Shon;Jong-Min Ko
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.299-299
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    • 2022
  • Whole wheat is rich in dietary fiber and contains various biological activity substances such as arabinoxylan, phytic acid and phenolic compounds. However, excessive fiber contents of whole wheat has a negative effect on dough formation, making it difficult to process. In this study, we tried to improve the usability of whole wheat by suggesting an appropriate degree of purification of whole wheat from 'Saekeumkang', a domestic wheat cultivar containing protein and gluten suitable for noodle production. The contents of arabinoxylan, phytic acid, and vitamin E were measured in the polishing rate range of 5-20% of whole wheat flour. As the milling ratio increased, the flour properties improved. The arabinoxylan and phytic acid content of whole wheat were 67.95 mg/g and 0.87 mg/g, but when milled at 20%, arabinoxylan and phytic acid were 60% and 80% of whole wheat, respectively. And as the milling ratio increased, the vitamin E content tended to decrease (whole wheat: 4.063 mg/100 g, 20% milled: 2.96 mg/100 g), However, the vitamin E composition ratio did not change. On the other hand, α-tocopherol showed the greatest than other vitamin E isomers. Therefore, further studies needed to optimize milling rate to improve the final product while maintaining the approximate nutritional and functional value of the whole wheat.

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한국산 녹차가 가축의 혈압 및 심박수에 미치는 영향 (Effects on blood pressure and heart rate in normal cats by administration of Korean native green tea)

  • 장정옥
    • 대한가정학회지
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    • 제25권1호
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    • pp.51-58
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    • 1987
  • This study was undertaken to investigate changes in blood pressure and heart rate in normal cats by administration of Korean native green tea. The chemical components of Korean native green tea which determined are water(2.2%), water extract(32.7%), vitamin C(480%), caffeine(2.6%), tannin(32.7%) and amino acid of water soluble content 5.8%. Effect on blood pressure in administration 100mg/kg, 300mg/kg, 500mg/kg of extract of green tea, the mean depressor response is 44.8$\pm$3.3mmHg, 60.5$\pm$3.6mmHg, and 65.0$\pm$3.3mmHg in normal cats. Effect on heart rate in administration 100mg/kg, 300mg/kg of extract of Korean native green tea, the mean decreased heart rate is 2.8$\pm$4.5 beats/min, 15.2$\pm$6.4beats/min and 19.1$\pm$4.0 beats/min.

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