• Tuberculosis and Respiratory Diseases
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• v.40 no.5
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• pp.584-594
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• 1993

Background: Among the respiratory diseases, there are a lot of cases of pleural effusion. The most common cause is tuberculosis. But the other cause such as lung malignancy is in an increasing tendency because of the development of diagnostic procedure, the decrease of the prevalence of the tuberculosis and the increase of the longevity. We need to know the accurate diagnosis as soon as possible for the correct therapy. Method: A clinical observation was made on 315 cases of pleural effusion seen at Pusan Adventist Hospital, from Jan, 1989 to Dec, 1992. For diagnostic procedure, thoracentesis, lymph node biopsy, bronchoscopy and percutaneous biopsy of the parietal pleura with Cope needle were performed. The following are parameters used in seperating the exudate from the transudate: pleural protein 3.0 g/dl, pleural protein/serum protein ratio 0.5, pleural LDH 200 IU, pleural LDH/serum LDH ratio 0.6, pleural cholesterol 60 mg/dl and pleural cholesterol/serum cholesterol ratio 0.3. Each parameters were compared, and misclassified rate and diagnostic efficiency were calculated. Results: The most common cause of exudate pleurisy was tuberculosis (82.3%) and malignancy was next (12.2%). The chief complaints of pleural effusion were noted as dyspnea (58.7%), chest pain (54.9%), coughing (50.2%) and fever (36.2%). Location of pleural effusion was noted as right side (51.4%), left side (41.3%) and both sides (7.3%). Amount of pleural effusion of the chest X-ray was minimum (46.8%), moderate (40.5%) and maximum (12.7%). Misclassified rates for each parameters in seperating the exudates from the transudates were as follows; protein: 5.2%, pleural protein/serum protein:7.6%, LDH: 13.9%, pleural LDH/serum LDH: 6.9%, cholesterol: 8.0%, pleural cholesterol/serum cholesterol: 5.6%. On the pleural biopsy, the tuberculosis granuloma was 60.8%, malignancy was 13.6%, infection was 2.3% and nonspecific inflammatory reaction was 23.3%. Conclusion: on the basis of the above results, the most common cause of exudative pleurisy was tuberculosis. We think that the plerual cholesterol/serum cholesterol ratio is the most useful supportive parameter in separating the exudates from the transudates. For accurate diagnosis, the pleural biopsy is the first procedure and repeated pleural biopsy of nonspedcific inflammatory reaction is required.

• Korean Journal of Ichthyology
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• v.13 no.1
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• pp.40-49
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• 2001

The ichthyofauna and fish community of the Dongjin River system were surveyed at 21 sites from October 1998 to September 1999. We confirmed the presence of 53 species in 14 families belonging to seven orders. Thirty-two species of cyprinid fishes accounted for 60.4% of the total, four species of cobitid and gobiid fishes 7.5% of the total, and two species of bagrid and centrarchid fishes for 3.8% of the total. The dominant species in the Dongjin River system was Zacco platypus (relative abundant 26.0%), the subdominant species was Carassius auratus (14.7%). The dominant and subdominant species in each stream of the Dongjin River system were determined. In the Dongjin River, the dominant species was Z. platypus (40.6%), the subdominant Acheilognathus lanceolatus (20.5%); in Wonpyeong stream, Pseudorasbora parva (22.6%) and Hypomesus olidus (13.2%); in Gobu stream C. auratus (67.5%) and Cyprinnus carpio (15.4%). Fourteen of the 53 species from the the Dongjin River system comprised 28.6% of the total Korean endemic species; seven rare species accounted for less than 0.1% of the total. Four exotic fish species were found: Cyprinus carpio (Islaeli carp), Carassius cuvieri, Micropterus salmoides and Lepomis macrochirus. The species dominance, diversity, and evenness index of the fish community from the Wonpyeong stream were 0.12, 1.08, and 0.91, respectively, indicating better conditions than those of the Dongjin River and the Gobu stream. The fish community of the Wonpyeong stream showed closer relationship to that of the Dongjin River than to that of the Gobu stream.

• Journal of Aquaculture
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• v.15 no.2
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• pp.95-101
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• 2002

During the periods from lily to October, 2000 in Hongseong and lucy to October, 2001 in Taean in the west coast of Korea, the following environmental conditions prevailed : water temperature : 22.0~26.817, salinity 27.23 ~30.80%, dissolved oxygen 4.12 ~6.26 ml/l, pH 7.89 ~8.09, phosphate 0.39 ~0.65 $\mu m$ , inorganic nitrogen 5.05~9.26 $\mu m$, suspended solid 5.4~20.8 mg/l and chemical oxygen demand 1.12~1.87 mg/l. The B-shaped veliger larvae of the Ark shell occurred in maximum number at $25^{\circ}C$ prevailing from mid-August at Hongseong and Taean. Full grown larvae reached maximum abundance from late August. To identify the effectiveness of the substratum for spat collection, raschel net were tested to Larval settlement. The most effective depth to collect the larvae in natural environment was the collectors suspended at 7~8 m depth. At these depths, about 49 to 94 spats were found on the collector (40$\times$50 cm), The growth of shell height (Y) to shell length (X), and total weight (W) to shell length (L) could be formulated as follows respectively: Hongseong: SH = 0.7168 SL -0.6466 ( $r^2$ = 0.9839), TW = $0.0001SL^{3.1705}$ ($r^2$ = 0.9882) Taean: SH = 0.736 SL -0.8824 ($r^2$ : 0.9899), TW : 0.00005 $SL^{3.3731}$ ($r^2$ : 0.9899)

• Clinical and Experimental Pediatrics
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• v.52 no.5
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• pp.581-587
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• 2009

Purpose : To evaluate the correlation between serum methotrexate (MTX) peak levels and clinical outcome of osteosarcoma, as well as to determine the correlation of these levels with the histologic response and event-free survival (EFS). Methods : To maintain the homogeneity of the study population, we selected 52 patients with localized extremity osteosarcoma who had received two cycles of neoadjuvant chemotherapy consisting of high-dose (HD) MTX ($12g/m^2$), cisplatin ($100mg/m^2$), and doxorubicin ($60mg/m^2$). Results : Totally, 204 courses of HD MTX were administered. The serial MTX levels ($mean{\pm}SE$) at 4 h (peak), 24 h, 48 h, and 72 h were $1292.14{\pm}12.83{\mu}m$, $9.29{\pm}3.89{\mu}m$, $1.73{\pm}1.37{\mu}m$, and $0.58{\pm}0.44{\mu}m$, respectively. The peak MTX serum level was $1292.14{\pm}12.83{\mu}m$. Neither the continuous average MTX peak level nor the dichotomized MTX peak level was related to the histologic response. However, the patients with a high 24-h MTX level ($3.4{\mu}m$) had a poor histologic response (P=0.044). An inverse relationship was observed between MTX levels and survival: the EFS was better in the patients with a mean MTX peak level of less than $1,400{\mu}m$ (P=0.002) and mean 24-h MTX level of less than $3.4{\mu}m$ (P=0.011). Conclusion : The inverse correlation between the MTX level and the outcome is an unexpected finding. Further study on the pharmacokinetics of MTX is required to substantiate our findings and elucidate the mechanism involved.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.19 no.4
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• pp.339-346
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• 1986

A study on eutrophication in the downstream of the Nakdong River was conducted from October 1983 to September 1984. Nutrients concentration of the samples in this area was usually high and the nitrogen ratio to the phosphorus was as very high as $63.5{\sim}119.6$. The concentration of nutrients was in the range of $0.22{\sim}173{\mu}g-at/l$ for ammonia nitrogen, $26.7{\sim}187{\mu}g-at/l$ for nitrate nitrogen, $1.07{\sim}8.22{\mu}g-at/l$ for nitrite nitrogen, $58.7{\sim}231{\mu}g-at/l$ for total inorganic nitrogen and $0.44{\sim}4.43{\mu}g-at/l$ for phosphate phosphorus. The concentration of chlorophyll-a was in the range of $1.8{\sim}75.2\;mg/m^3$. Correlationship between concentration of nutrients and chlorophyll-a was not found. The concentrations of total suspended solid were in the range of $10.7{\sim}45.9\;ppm$, and $16.2{\sim}35.2\%$ of the total suspended solid was consisted of volatile suspended solid. According to the state of lacustrine nutrition, the state of the downstream of Nakdong River was equivalent to the eutrophication state in term of chlorophyll-a and inorganic nitrogen, and mid-nutritional state in term of phosphate.

• Archives of design research
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• v.13 no.1
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• pp.209-218
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• 2000

The purpose of this study was to improve the curriculum for industrial design department in the junior colleges. In order to achieve the purpose, two methodologies were carried out. First is job analysis of the industrial designers who have worked in the small & medium manufacturing companies, second is survey for the opinions of professors in the junior colleges. Some results were as follows: 1. The period of junior college for industrial designers is 2 years according to present. But selectively 1 year of advanced course can be established. 2. The practice subjects same as computational formative techniques needed to product development have to be increased. In addition kinds of selection subjects same as foreign language, manufacturing process, new product information and consumer behavior investigation have to be extended. 3. The next subjects need to adjust the title, contents and hours. (1) The need of 3.D related subjects same as computer modeling, computer rendering, 3.D modeling was high. The use of computer is required to design presentation subjects. (2)The need of advertising and sale related subjects same as printing, merchandise, package, typography, photography was low, the need of presentation techniques of new product development was high. (3) The need of field practice, special lecture on practice and reading original texts related subjects was same as at present, but these are not attached importance to form. As the designers feel keenly the necessity of using foreign language, the need of language subject was high.

• Journal of the Korea Organic Resources Recycling Association
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• v.2 no.2
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• pp.89-98
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• 1994

A survey was carried out in Seoul Metropolitan area during December of 1993 and January of 1994. The objective of the survey was to provide a useful information for the development and improvement of recycling policies, regulations and systems in Korea. Of the 782 individuals contacted, 473 individuals completed and retured surveys, of which 437 were usable. The results were analyzed using a statistical package SAS(Statistical Analysis System). The results indicated that 86% of apartment area has recycling bins, while only 33% of individual house(detached dwelling) area has those. About half of the respondents felt that food waste is the major source of household waste. The most serious problem to recycle more household waste is to provide space to store recyclables at the source. The majority of Seoul Metropolitans(78.5%) are willing to participate in recycling programs, while 14.4% want to participate only when there are economic incentives or benefits. Respondents who want economic incentives appeared to be low income people. 66.1% of total respondents said that they do not use disposables. However, only 53,0% among respondents under 30 years old answered they do not use disposables. People who graduated from middle high school only and are under 30 years old have tendency to dispose of used milk cartons without rincing and drying, while those who are over 40 years old and graduated from university prefered to rinse and dry used milk cartons before disposal. Regarding disposal of newspapers, only 43.9% of the total respondents separated newspaper from other types of used paper. In the case of alumium cans, 22.5% of the total respondents answered that used aluminum cans are not recyclables. Much higher portion (30. 4%) of the respondents who graduated from middle high school only felt that aluminum cans have no value to recycle. The results indicated that education and information regarding recycling are highly desirable.

• Clinical and Experimental Pediatrics
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• v.50 no.10
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• pp.970-975
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• 2007

Purpose : Accurate measurement of defect size is important in transcatheter closure of atrial septal defect (ASD). We performed this study to analyze the difference between the measured ASD size and balloon occlusive diameter (BOD) by transthoracic (TTE) or transesophageal echocardiography (TEE). Methods : We investigated 78 patients who underwent transcatheter closure of ASD. The defect size and the distance between the surrounding structures were measured by TTE and TEE. The BOD was measured by TEE during cardiac catheterization. Clinical characteristics and echocardiographic data were compared and analyzed. Results : The difference between BOD and diameter by TTE was $4.8{\pm}3.6mm$ on short axis view, $5.4{\pm}3.2mm$ on long axis view. The difference between BOD and diameter by TEE was $3.6{\pm}2.2mm$ on short axis view, $4.2{\pm}3.1mm$ on long axis view. The difference between BOD and the diameter of defects on TTE, TEE had statistically significant positive correlations with the age of the patients, distance between the, defect and posterior atrial septal wall, the distance between the defect and the mitral valve leaflet, and the diameter of defects and the length of the atrial septum on TTE (P<0.05). Conclusion : BOD of ASD can be estimated by the diameter on TTE and TEE. BOD is expected to measure larger, depending on the size of defects, the distance from surrounding structures and the location of defects on echocardiography. Our data offers important information on details of transcatheter ASD closure which can be helpful in predicting suitability and judging the procedural appropriateness during the procedure.

• The Journal of Korean Society for Radiation Therapy
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• v.15 no.1
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• pp.29-33
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• 2003

I. Purpose Brachytherapy is the main component in treatment of patients with uterine cervical cancer. The reproducibility of applicator position in the same patient at repeated treatments was very important for accurate dose delivery. It was aimed to evaluate the change of applicator location between each high dose rate(HDR) brachytherapy insertion in the patients with uterine cervical cancer. II. Materials and Methods From January 1999 to October 2001, total 52 patients were treated with external beam radiotherapy and HDR brachytherapy (Microselectron, Nucletron). During six to seven times of brachytherapy, all patients had three treatment plans. From the orthogonal radiographs, we measured the following variables; height from upper border of pubic bone to os (HPO), distance from sacral promontory to tip of tandem (DST), distance from coccyx to os (DCO), distance from tip of right ovoid to os (DRO), distance from tip of left ovoid to os (DLO), and distance from center of the first tandem source to ovoid (DTO). To evaluate the reproducibility of applicator position, it was calculated the standard deviation of differences between three insertions for the 7 parameters in each patient. III. Results The ranges of standard deviations of interfractional differences for the variables were as follows. 1)HPO : $0{\sim}0.79cm$ 2)DST : $0{\sim}0.9cm$ 3)DCO : $0.06{\sim}0.76cm$ 4)DRO : $0{\sim}0.53cm$ 5)DLO : $0{\sim}0.45cm$ 6) DTO $0{\sim}0.36cm$ IV. Conclusions There was some change in applicator position on repeated implants in our study. But variation of the interfractional differences was minimal; in all parameters, there were less than 1 cm. We are continued to try for reducing the geometric variation between each procedure.

• Childhood Kidney Diseases
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• v.12 no.2
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• pp.178-185
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• 2008

Purpose : Our aim was to investigate the predictive factors for detecting grade III-V vesicoureteral reflux(VUR) in young infants less than 3 months with urinary tract infections (UTI). Methods : Data of infants who underwent ultrasonography and VCUG between January 2004 and September 2007 were reviewed. Age, gender, incidence of bacteremia, C-reactive protein(CRP) and imaging studies were compared between group I(grade III-V VUR) and group II (normal or grade I and II VUR) retrospectively. Sensitivity, specificity, positive and negative predictive values, odds ratio, and likelihood ratio of ultrasonography for high grade VUR were evaluated. Results : Among 54 enrolled infants(41 males, 13 females), 14 infants were group I and 40 infants were group II. In the group I, CRP level was significantly higher(6.11$\pm$5.18 vs. 3.27$\pm$3.45, P=0.025), and there were more ultrasonographic abnormal findings(71.4%, vs. 22.5%, P=0.002) compared with group II. However, ultrasonography was the only significant factor after adjusting with logistic regression(P=0.002). Incidence of bacteremia and abnormal DMSA findings were not significantly different in two groups. Sensitivity, specificity, and odds ratio of ultrasonography was 71.4%, 77.5%, 6.9 respectively. Negative predictive value was 88.6% and negative likelihood ratio was 0.37. Ultrasonography had significant negative likelihood ratio for grade III-V VUR, but missed 4 infants with grade III VUR. Conclusion : We could not find any alternative predictive factors to reduce VCUG in detecting high grade VUR. Therefore, VCUG must be considered in young infants less than 3 months with UTI.