• Journal of the Korean Society for Precision Engineering
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• v.21 no.8
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• pp.164-170
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• 2004

The skin movement artifacts are referred to as the relative motion of skin with respect to the motion of underlying bones. This is of great importance in joint biomechanics or internal kinematics of human body. This paper describes a novel experiment that measures the skin movement of a hand based on MR(magnetic resonance) images in conjunction with surface modeling techniques. The proposed approach consists of 3 phases: (1) MR scanning of a hand with surface makers, (2) 3D reconstruction from the MR images, and (3) registration of the 3D models. The MR images of the hand are captured by 3 different postures. And the surface makers which are attached to the skin are employed to trace the skin motion. After reconstruction of 3D models from the scanned MR images, the global registration is applied to the 3D models based on the particular bone shape of different postures. The results of registration are then used to trace the skin movement by measuring the positions of the surface markers.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.8
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• pp.1809-1818
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• 2010

In order to detect the skin color area from input images, many prior researches have divided an image into the pixels having a skin color and the other pixels. In a still image or videos, it is very difficult to exactly extract the skin pixels because lighting condition and makeup generate a various variations of skin color. In this thesis, we propose a method that improves its performance using hierarchical merging of 3D skin color model and context informations for the images having various difficulties. We first make 3D color histogram distributions using skin color pixels from many YCbCr color images and then divide the color space into 3 layers including skin color region(Skin), non-skin color region(Non-skin), skin color candidate region (Skinness). When we segment the skin color region from an image, skin color pixel and non-skin color pixels are determined to skin region and non-skin region respectively. If a pixel is belong to Skinness color region, the pixels are divided into skin region or non-skin region according to the context information of its neighbors. Our proposed method can help to efficiently segment the skin color regions from images having many distorted skin colors and similar skin colors.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.3
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• pp.729-733
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• 2004

Jaeum-Dan was reported new anti-aging effect formula previously. We investigated the physiological effects on human skin with Jaeum-Dan essence (JED). We made a skin application product as essence form contained oriental herbs, and measured various physiological effects such as skin moisture contents, red blood cell flow rates, skin surface temperature, corneocyte exfoliation and skin intensity when volunteers(female, n=40) used the application product for 4 weeks. The results were as follows: The skin moisture contents were not only increased in human face skin through using the product, but also red blood cell flow :rates in face skin were increased. After using the essence, the face skin temperature rose and corneocyte exfoliation was decreased. Furthermore the upper dermis intensity of skin in female face was subsequently increased 4 weeks later. The results indicate that the application product containing JED was improved the physiological effects of human facial skin..

• The Journal of the Korea Contents Association
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• v.9 no.5
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• pp.1-12
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• 2009

The correct detection of skin color is an important preliminary process in fields of face detection and human motion analysis. It is generally performed by three steps: transforming the pixel color to a non-RGB color space, dropping the illuminance component of skin color, and classifying the pixels by the skin color distribution model. Skin detection depends on by various factors such as color space, presence of the illumination, skin modeling method. In this paper we propose a 3d skin color model that can segment pixels with several ethnic skin color from images with various illumination condition and complicated backgrounds. This proposed skin color model are formed with each components(Y, Cb, Cr) which transform pixel color to YCbCr color space. In order to segment the skin color of several ethnic groups together, we first create the skin color model of each ethnic group, and then merge the skin color model using its skin color probability. Further, proposed model makes several steps of skin color areas that can help to classify proper skin color areas using small training data.

• KSBB Journal
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• v.31 no.3
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• pp.178-185
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• 2016

Aging of the face is mainly related to the features that are sagging or loss of elasticity of the skin by reducing the volume around the eyes or cheek. Intrinsic aging can be seen to cause thinner dermis, reduction of extracellular matrix and subcutaneous fat. This study was carried out to investigate the skin volume augmentation and anti-wrinkle effects of Tribulus terrestris fruit extract. Skin anti-aging effect of Tribulus terrestris fruit extract was evaluated by using lipid accumulation, expressin of type I procollagen and elastin in preadipocytes and human dermal fibroblasts. Tribulus terrestris fruit extract augmented preadipocytes differentiation about 56% at 100 µg/mL. The type I procollagen and elastin were increased about 35% and 25% by treatment 20% Tribulus terrestris fruit extract, respectively. The clinical study also showed that skin sagging, skin elasticity, and dermal density improved without adverse effect following 4 week application of cream containing 2% Tribulus terrestris fruit extract. We suggest that Tribulus terrestris fruit extract can have the good possibility as skin volume augmenting, skin elasticity and wrinkle improving agent.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.14 no.2
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• pp.73-79
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• 2008

Objectives : We investigated the correlation of the skin color to blood circulation on the face of Korean female by noninvasive-skin measuring devices. Methods : Korean female(37.47${\pm}$3.66 years, n=36) aged 30-45 years were participated in this study. We measured the skin color of the face with Spectrophotometer CM2600d (Minolta, Japan) and the skin blood flow with Laser Doppler Imaging-Periscan PIM II (Perimed AB, Sweden). The skin color and blood circulation of three groups (30-35 years, 36-40 years, 41-45 years) divided on age were analyzed by paired-t test and regression analysis. Results : The L* values of the skin were decreased and the a* values were increased significantly with age. This means that the more age increase, the more the skin is dark and red. But the skin blood flow was not significantly different with age and skin color. Conclusions : In the oriental medicine, It was reported that the face of the female over 35 years is changed gradually haggard and the blood circulation is decreased. In our study, the blood circulation was not changed and the skin color was dark and red with increasing the age. We think this symptom resulted from the better nutrition than the past, the change of the blood-quality and this changes were too sensitive to be measured by Laser Doppler Imaging system.

• Journal of Pharmaceutical Investigation
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• v.33 no.3
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• pp.163-169
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• 2003

In order to develop a film-forming transdermal drug delivery system, polyurethane (PU) based on poly(ethylene glycol) and poly(tetramethylene oxide) was synthesized and characterized. The synthesized PU was blended with Gantrez ES 225 (GT) to improve the adhesion property of film-forming agent to the skin. When film-forming gel formulation containing 3% ketoprofen (KP) was applied, transparent thin film was obtained within 5 minutes and adhered to the skin for 8 hours. In vitro percutaneous absortion studies were performed to determine the rate of ketoprofen absorption through guinea pig skin. A prominent effect of limonene on the skin permeability of ketoprofen was observed among the various skin permeation enhancers investigated. Considering mechanica properties of film and skin permeability of ketoprofen, 2% of limonene was optimal content in the film forming transdermal formulation.

• Toxicological Research
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• v.33 no.3
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• pp.191-203
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• 2017

Human eyes and skin are frequently exposed to chemicals accidentally or on purpose due to their external location. Therefore, chemicals are required to undergo the evaluation of the ocular and dermal irritancy for their safe handling and use before release into the market. Draize rabbit eye and skin irritation test developed in 1944, has been a gold standard test which was enlisted as OECD TG 404 and OECD TG 405 but it has been criticized with respect to animal welfare due to invasive and cruel procedure. To replace it, diverse alternatives have been developed: (i) For Draize eye irritation test, organotypic assay, in vitro cytotoxicity-based method, in chemico tests, in silico prediction model, and 3D reconstructed human cornealike epithelium (RhCE); (ii) For Draize skin irritation test, in vitro cytotoxicity-based cell model, and 3D reconstructed human epidermis models (RhE). Of these, RhCE and RhE models are getting spotlight as a promising alternative with a wide applicability domain covering cosmetics and personal care products. In this review, we overviewed the current alternatives to Draize test with a focus on 3D human epithelium models to provide an insight into advancing and widening their utility.

• Journal of the Korean Geotechnical Society
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• v.22 no.10
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• pp.47-54
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• 2006

H-pile can be more easily driven than pipe pile by pile driver and shows high skin friction and plugging effect. This experimental study was devoted to investigate skin friction of H group piles in granite soil under laboratory test. Pile arrangements $(1{\times}2,\;1{\times}3,\;2{\times}2,\;2{\times}3,\;3{\times}3)$, pile space (2D,4D,6D), and soil density $(D_r=40%,\;80%)$ were tested. The main results obtained from the model tests can be summarized as follows. Distribution ratio of skin friction for total load decreased by $48{\sim}39%$ (dense soil), $32{sim}27%$ (loose soil) as piles space ratio increases in case of $3{\times}3$ group piles. And the distribution ratio of skin friction by pile settlements under loose soil decreased by about $58{\sim}33.2%$ in $2{\times}2$ group piles and about $65{\sim}38%$ in $3{\times}3$ group piles respectively.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.23 no.3
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• pp.39-47
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• 1997

Retinol as well as RA is well known to have many beneficial effects on aged skin. But the skin irritation potential and unstable condition of the products containing them have been some problems in their cosmetic uses. So, retinol containing gel product was developed for less skin irritancy and more stability in cosmetic products. To examine the clinical effects of retinlo containing product, we used cilnicla non-invasive assessment techniques on 40 volunteers for 6 months maintaining double-blind test conditions. According to our results, the use of retinol containing product improved skin color and hydration level slightly. But there was no statistical differences. There was no erythema reaction compared to the use of RA. Especially, the skin elasticity increased above 20% and skin wrinkles of crows' feet region decreased more than 10%. Besides the instrumental analysis, a large majority of volnteers felt that their skin were improved in the case of wrunkles, elasticity, hydration and color.