• Prospectives of Industrial Chemistry
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• v.23 no.3
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• pp.1-16
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• 2020

식품 산업에서 제품의 품질을 향상시키기 위해서는 약한 세기의 맛에서도 다양한 종류의 맛을 감지해낼 수 있어야만 한다. 이러한 목적 달성을 위해서 2차원 물질과 금속유기골격체(metal-organic framework, MOF)를 이용한 미각 감지 센서에 대한 연구들이 한창 진행 중이다. 2차원 물질 및 MOF는 고유한 특성으로 인하여 현재 다양한 분야에서 많은 관심을 받아오고 있으며 화학 및 생화학 감지 등 다양한 분야에서도 응용될 수 있다. 본 기고문에서는 미각 감지 응용에서 2차원 물질과 MOF의 최신 연구동향을 다루고자 한다. 본 기고문을 통하여 미각 감지 응용 분야에서 2차원 물질과 MOF의 작용 메커니즘을 이해하고 현재의 연구 현황 및 앞으로의 발전 방향을 알아보고자 한다.

• BMB Reports
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• v.56 no.1
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• pp.10-14
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• 2023

Organoids derived from stem cells or organ-specific progenitors are self-organizable, self-renewable, and multicellular three-dimensional (3D) structures that can mimic the function and structure of the derived tissue. Due to such characteristics, organoids are attracting attention as an excellent ex vivo model for drug screening at the stage of drug development. In addition, since the applicability of organoids as therapeutics for tissue regeneration has been embossed, the development of various organoids-based regenerative medicine has been rapidly progressing, reaching the clinical trial stage. In this review, we give a general overview of organoids and describe current status and prospects of organoid-based regenerative medicine, focusing on organoid-based regenerative therapeutics currently under development including clinical trials.

• BMB Reports
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• v.55 no.12
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• pp.587-594
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• 2022

A persistent DNA tumor virus infection transforms normal cells into cancer cells by either integrating its genome into host chromosomes or retaining it as an extrachromosomal entity called episome. Viruses have evolved mechanisms for attaching episomes to infected host cell chromatin to efficiently segregate the viral genome during mitosis. It has been reported that viral episome can affect the gene expression of the host chromosomes through interactions between viral episomes and epigenetic regulatory host factors. This mini review summarizes our current knowledge of the tethering sites of viral episomes, such as EBV, KSHV, and HBV, on host chromosomes analyzed by three-dimensional genomic tools.

• International conference on construction engineering and project management
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• 2005.10a
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• pp.841-844
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• 2005

Computer vision technology can be used to interpret the images captured by web cameras installed on construction sites to automatically quantify the results. This information can be used for quality control, productivity measurement and to direct construction. Steel frame construction is particularly well suited for automatic monitoring as all structural members can be viewed from a small number of camera locations, and three-dimensional computer models of steel structures are frequently available in a standard electronic format. A system is being developed that interprets the 3-D model and directs a camera to look for individual members as regular intervals to determine when each is in place and report the results. Results from a simple lab-scale system are presented along with preliminary full-scale development.

• Proceedings of the Korean Nuclear Society Conference
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• 1997.10a
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• pp.591-598
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• 1997

The COBRA/RELAPS code, an integrated version of the COBRA-TF and RELAP5/MOD3 codes, has been developed for the realistic simulations of complicated, multi-dimensional, two-phase, thermal-hydraulic system transients in light water reactors. Recently, KAERA developed an unified version of the COBRA/RELAP5 code, which can run in serial mode on both workstations and personal computers. This paper provides the brief overview of the code integration scheme, the recent code modifications, the developmental assessments, and the future development plan.

• Archives of Plastic Surgery
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• v.50 no.1
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• pp.96-100
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• 2023

The microsurgical anastomosis is integral to the success of autologous-free tissue transfer. Successful performance of this procedure relies strongly on operator dexterity, which can be made more challenging when blood and edematous fluids obscure the field of view. Workflow is impeded by intermittent irrigation and suctioning, necessitating presence of an assistant, with risk of arterial thrombosis, from vessels being drawn into suction drains. To negate these current disadvantages and minimize the barrier of entry to microvascular operations, we designed, manufactured, and patented a novel three-dimensional printed microsurgical background device with microfluidic capabilities that allow continuous suction and irrigation as well as provide platforms that enable multiangle retraction to facilitate operator autonomy. This was validated in an ex vivo model, with the device found to be superior to the current standard. We believe that this will have major applicability to the improvement of microsurgeon

• Earthquakes and Structures
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• v.22 no.5
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• pp.527-538
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• 2022

In this paper the free vibration frequencies of tri-directional functionally graded materials imperfect plate is investigated for Several plate geometries with two types of porosity (even and uneven) and different type of material configuration. The effect of several parameters such as power law index and boundary conditions have been investigated. For this purpose, an efficient computational method is developed and written under Matlab environment, based on a three-dimensional modeling and the isogeometric method is used for the discretization of the structure based on NURBS (Nonuniform rational B-spline) basis functions. The results obtained by the present method are validated by the comparison with the results given by several authors in the literature.

• Electronics and Telecommunications Trends
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• v.38 no.3
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• pp.1-10
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• 2023

In this study, the status of global advanced air mobility (AAM) was investigated to derive information and communications technologies (ICTs) that should be prepared according to directions of domestic AAM development. AAM is an urban air traffic system for moving from city to city by electric vertical take-off and landing or personal aircraft. It is expected to establish a three-dimensional air traffic system that can solve ground traffic congestion caused by the rapid global urbanization. With the full-scale commercialization of AAM solutions, high-density air traffic is expected, and with the advent of the personal air vehicle (PAV), the flight space usage is expected to expand. Therefore, it is necessary to develop a safe AAM service through early research on core ICTs for autonomous flight.

• Computers and Concrete
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• v.32 no.2
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• pp.139-148
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• 2023

The purpose of this paper is to numerically assess the seismic performance of deteriorated reinforced concrete columns using a new plastic-hinge element. Developing a three dimensional (3D) nonlinear model can be difficult and computationally complex, and there can be problems applying it in the field. Thus, to solve these problems, a plastic-hinge element that could considers the shear deformation of deteriorated reinforced concrete columns was proposed. The developed element was based on the Timoshenko beam model and used two nodes with six degrees of freedom and a zero-length element. Moreover, the developed model could consider the combined effects of corrosion, as demonstrated by the reduced reinforcement area and the loss of bond. Consequently, the numerical procedures developed for evaluating the seismic performance of deteriorated columns were validated by comparing the verification results.

• Nuclear Engineering and Technology
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• v.56 no.6
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• pp.2292-2306
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• 2024

This study addresses cracks and fracture problems in engineering structures that may cause significant challenges and safety concerns, with a focus on pressure vessels in nuclear power plants. Comprehensive parametric three-dimensional mixed mode fracture analyses for inclined and deflected nozzle corner cracks with various crack shape aspect ratios and depth ratios in nuclear reactor pressure vessels are carried out. Stress intensity factor (SIF) solutions are obtained using FRAC3D, which is part of Fracture and Crack Propagation Analysis System (FCPAS), employing enriched finite elements along the crack front. Also, improved empirical equations are developed to allow the determination of mixed mode SIFs, K_I, K_II, and K_III, for any values of the parameters considered in the study. This study provides practical solutions to assess the remaining life and fail-safe conditions of nuclear reactors by providing accurate SIF determination.