• 제목/요약/키워드: 3D(three-dimensional)

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Head and neck extra nodal NHL (HNENL) - Treatment Outcome and Pattern of failure - A Single Institution Experience

  • Giridhar, Prashanth;Mallick, Supriya;Bhasker, Suman;Pathy, Sushmita;Mohanti, Bidhu Kalyan;Biswas, Ahitagni;Sharma, Atul
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6267-6272
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    • 2015
  • Background: Extra nodal lymphoma (ENL) constitutes about 33 % of all non-Hodgkin's lymphoma. 18-28% develops in the head and neck region. A multimodality treatment with multi-agent chemotherapy (CT) and radiotherapy (RT) is considered optimum. Materials and Methods: We retrieved the treatment charts of patients of HNENL treated in our institute from 2001-2012. The charts were reviewed and the demographic, treatment details and outcome of HNENL patients were retrieved using predesigned pro-forma. Results: We retrieved data of 75consecutive patients HNENL. Median age was 47years (Range: 8-76 years). Of the 75 patients 51 were male and 24 were female. 55patients were evaluable. The patient and tumor characteristics are summarized in Table 1. All patients were staged comprehensively with contrast enhanced computed tomography of head, neck, thorax, abdomen, pelvis and bone marrow aspiration and biopsy 66 patients received a combination multi-agent CT with CHOP being the commonest regimen. 42 patients received 4 or lesser number of cycles of chemotherapy whereas 24received more than 4 cycles chemotherapy. Post radiotherapy, 41 out of 42 patients had a complete response at 3 months. Only 21patients had a complete response after chemotherapy. All patients received radiation (mostly involved field radiation) as a part of the treatment. The median radiation dose was 45 Gray (Range: 36 Gray-50 Gray). The radiation was planned by 2D fluoro simulation based technique in 37cases and by 3 Dimensional conformal radiation therapy (3DCRT) in 36 cases. Two patients were planned by the intensity modulated radiation therapy (IMRT) technique. IMRT was planned for one thyroid and one nasal cavity primary. 5 patients experienced relapse after a median follow up of 19 months. The median survival was not reached. The estimated two and three year survival were 92.9% (95%CI- 68.6- 95.35) and 88% (95%CI- 60.82 - 92.66) respectively. Univariate analysis revealed higher stage and poorer baseline performance status to be significantly associated with worse progression free survival. 5 patients progressed (relapse or primary disease progression) after treatment. Of the 5 patients, two patients were primary orbital NHL, two patients had NHL nasal cavity and one was NHL thyroid. Conclusions: Combined modality treatment in HNENL confers excellent disease control with acceptable side effects.

Three-Dimensional Kinematic Model of the Human Knee Joint during Gait

  • Mun, Joung-Hwan;Seichi Takeuchi
    • Journal of Biomedical Engineering Research
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    • v.23 no.3
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    • pp.171-179
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    • 2002
  • It is well known that the geometry of the articular surface plays a major role in the kinematic and kinetic analysis to understand human knee joint function during motion. The functionality of the knee joint cannot be accurately modeled without considering the effects of sliding and lolling motions. We Present a 3-D human knee joint model considering sliding and rotting motion and major ligaments. We employ more realistic articular geometry using two cam profiles obtained from the extrusion of the sagittal Plain view of the representative Computerized Tomography image of the knee joint compared to the previously reported model. Our model shows good agreement with the already reported experimental results on Prediction of the lines of force through the human joint during gait. The contact point between femur and tibia moves toward the Posterior direction as the knee undergoes flexion, reflecting the coupling of anterior and Posterior motion with flexion/extension. The anterior/posterior displacement of the contact Point on the tibia plateau during one gait cycle is about 16 mm. for the lateral condyle and 25 mm. for the medial condyle using the employed model Also. the femur motion on the tibia undergoes lateral/medial movement about 7 mm. and 10 mm. during one gait cycle for the lateral condyle and medial condyle. respectively. The developed computational model maybe Potentially employed to identify the joint degeneration.

Nondestructive Diagnosis of NPP Piping System Using Ultrasonic Wave Imaging Technique Based on a Pulsed Laser Scanning System (펄스 레이저 스캐닝 기반 초음파 영상화 기술을 활용한 원전 배관 비파괴 진단)

  • Kim, Hyun-Uk;Lee, Chang-Gil;Park, Seung-Hee
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.1
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    • pp.166-173
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    • 2014
  • A noncontact nondestructive testing (NDT) method is proposed to detect the damage of pipeline structures and to identify the location of the damage. To achieve this goal, a scanning laser source actuation technique is utilized to generate a guided wave and scans a specific area to find damage location more precisely. The ND: YAG pulsed laser is used to generate Lamb wave and a piezoelectric sensor is installed to measure the structural responses. The measured responses are analyzed using three dimensional Fourier transformation (3DFT). The damage-sensitive features are extracted by wavenumber filtering based on the 3D FT. Then, flaw imaging techniques of a pipeline structures is conducted using the damage-sensitive features. Finally, the pipes with notches are investigated to verify the effectiveness and the robustness of the proposed NDT approach.

Seismic Response from Microtremor of Chogye Basin, Korea (초계분지의 상시미동 지진응답)

  • Lee, Heekyoung;Kim, Roungyi;Kang, Tae-Seob
    • Geophysics and Geophysical Exploration
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    • v.20 no.2
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    • pp.88-95
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    • 2017
  • Chogye basin, which is surrounded by country rock, has a closed-basin form. In such a basin, incident seismic energy can form multiply reflected waves, thus causing energy concentration to occur at this closed-basin area. Microtremor measurement survey was performed at the Chogye basin, which is located in Chogye-myeon and Jeokjungmyeon, Hapcheon-gun, Gyeongsangnam-do, Republic of Korea. Microtremor data were transformed into the frequency domain, and then the horizontal-to-vertical spectral ratios (HVSR) were calculated. Fundamental resonance frequencies were estimated from the HVSR results for every observation point. Using the empirical relationship between site period and thickness for sediment sites in Korea known from the previous study, the distribution of sediment thickness of the Chogye basin was estimated from the fundamental resonance frequencies. Being compared with the mountainous rim with steep slope, the measurement points inside the basin have low values of the fundamental resonance frequency with the minimum of 1.03 Hz, which corresponds to the thickness of sedimentary layer with the maximum depth of about 100 m. A three-dimensional basin model was constructed for bedrock topography of the Chogye basin by an interpolation of basin depths estimated at each measurement site.

Bone Segmentation Method based on Multi-Resolution using Iterative Segmentation and Registration in 3D Magnetic Resonance Image (3차원 무릎 자기공명영상 내에서 영역화와 정합 기법을 반복적으로 이용한 다중 해상도 기반의 뼈 영역화 기법)

  • Park, Sang-Hyun;Lee, Soo-Chan;Yun, Il-Dong;Lee, Sang-Uk
    • Journal of Broadcast Engineering
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    • v.17 no.1
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    • pp.73-80
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    • 2012
  • Recently, medical equipments are developed and used for diagnosis or studies. In addition, demand of techniques which automatically deal with three dimensional medical images obtained from the medical equipments is growing. One of the techniques is automatic bone segmentation which is expected to enhance the diagnosis efficiency of osteoporosis, fracture, and other bone diseases. Although various researches have been proposed to solve it, they are unable to be used in practice since a size of the medical data is large and there are many low contrast boundaries with other tissues. In this paper, we present a fast and accurate automatic framework for bone segmentation based on multi-resolutions. On a low resolution step, a position of the bone is roughly detected using constrained branch and mincut which find the optimal template from the training set. Then, the segmentation and the registration are iteratively conducted on the multiple resolutions. To evaluate the performance of the proposed method, we make an experiment with femur and tibia from 50 test knee magnetic resonance images using 100 training set. The proposed method outperformed the constrained branch and mincut in aspect of segmentation accuracy and implementation time.

Depth Image Poselets via Body Part-based Pose and Gesture Recognition (신체 부분 포즈를 이용한 깊이 영상 포즈렛과 제스처 인식)

  • Park, Jae Wan;Lee, Chil Woo
    • Smart Media Journal
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    • v.5 no.2
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    • pp.15-23
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    • 2016
  • In this paper we propose the depth-poselets using body-part-poses and also propose the method to recognize the gesture. Since the gestures are composed of sequential poses, in order to recognize a gesture, it should emphasize to obtain the time series pose. Because of distortion and high degree of freedom, it is difficult to recognize pose correctly. So, in this paper we used partial pose for obtaining a feature of the pose correctly without full-body-pose. In this paper, we define the 16 gestures, a depth image using a learning image was generated based on the defined gestures. The depth poselets that were proposed in this paper consists of principal three-dimensional coordinates of the depth image and its depth image of the body part. In the training process after receiving the input defined gesture by using a depth camera in order to train the gesture, the depth poselets were generated by obtaining 3D joint coordinates. And part-gesture HMM were constructed using the depth poselets. In the testing process after receiving the input test image by using a depth camera in order to test, it extracts foreground and extracts the body part of the input image by comparing depth poselets. And we check part gestures for recognizing gesture by using result of applying HMM. We can recognize the gestures efficiently by using HMM, and the recognition rates could be confirmed about 89%.

Determination of Volume Porosity and Permeability of Drainage Layer in Rainwater Drainage System Using 3-D Numerical Method (3차원 수치해석기법을 이용한 우수배수시스템 배수층의 체적공극과 투수도 결정)

  • Yeom, Seong Il;Park, Sung Won;Ahn, Jungkyu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.8
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    • pp.449-455
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    • 2019
  • The increase in impermeable pavement from recent urbanization has resulted in an increase in surface runoff. The surface runoff has also increased the burden of the existing drainage system. This drainage system has structural limitations in that the catchment area is reduced by the waste particles transported with the surface runoff. In addition, the efficiency of the drainage system is decreased. To overcome these limitations, a new type of drainage system with a drainage layer was developed and applied. In this study, various volume porosity and permeability of the lower drainage layer were simulated using ANSYS CFX, which is a three dimensional computational fluid dynamics program. The results showed that the outlet velocity of the 35% volume porosity was faster than that of the 20% and 50% cases, and there was no relationship between the volume porosity and drainage performance. The permeability of the drainage layer can be determined from the particle size of the material, and a simulation of five conditions showed that 2 mm sand grains are most suitable for workability and usability. This study suggests appropriate values of the volume porosity and particle size of the drainage layer. This consideration can be advantageous for reducing and preventing flood damage.

A Numerical study on characteristics of fluid flow in a three-dimensional discrete fracture network with variation of length distributions of fracture elements (3차원 이산 균열망 흐름장에서 균열요소의 길이분포 변화에 따른 내 유체 흐름 특성에 관한 수치적 연구)

  • Jeong, Woochang
    • Journal of Korea Water Resources Association
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    • v.52 no.2
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    • pp.149-161
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    • 2019
  • In this study, the effect of the fluid flow characteristics on the length distribution of the fracture elements composing the fracture network is analyzed numerically using the 3D fracture crack network model. The truncated power-law distribution is applied to generate the length distribution of the fracture elements and the simulations of fluid flow are carried out with the exponent ${\beta}_l$ from 1.0 to 6.0. As a result of simulations, when the exponent ${\beta}_l$ increases, the length distribution of the fracture elements gradually decreases, and the connectivity between the fracture elements affecting the permeability of the fracture network becomes weak. When we analyzed the distributions of flow rate calculated at each fracture element with the exponent ${\beta}_l$, the mean flow rate at ${\beta}_l=1.0$ was estimated to be about 447 times larger than that at ${\beta}_l=6.0$ and for the flow calculated at the outflow boundary of the fracture network, the case of ${\beta}_l=1.0$ was estimated to be 6,440 times larger than that of ${\beta}_l=6.0$.

Seismic Performance Evaluation of Dam Structures and Penstock Considering Fluid-Structure Interaction (유체-구조물 상호작용을 고려한 댐 구조체와 수압철관의 내진성능평가)

  • Heo, So-Hyeon;Nam, Gwang-Sik;Jeong, Yeong-Seok;Kwon, Minho
    • Land and Housing Review
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    • v.13 no.1
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    • pp.141-150
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    • 2022
  • Responding to the increasing demand for research on seismic resistance of structures triggered by a large-scale earthquake in Korea, the Ministry of the Interior and Safety revised the typical application of the existing seismic design standards with the national seismic performance target enhanced. Therefore, in this paper, the dam body of the aged Test-Bed and the penstock with fluid were modeled by the three-dimensional finite element method by introducing several variables. The current seismic design standard law confirmed the safety of the dam structure and penstock against seismic waves. As a result of the 3D finite element analysis, the stress change due to the water impact of the penstock was minimal, and it was confirmed that the effect of the hydraulic pressure was more significant than the water impact in the earthquake situation. When the hydrostatic pressure is in the form of SPH, it was analyzed that the motion of the fluid and the location of stress caused by the earthquake can be effectively represented, and it will be easier to analyze the weak part. As a result of the analysis, which considers penstock's corrosion, the degree of stress dispersion gets smaller because the penstock is embedded in the body. The stress result is minimal, less than 1% of the yield stress of the steel. In addition, although there is a possibility of micro-tensile cracks occurring in the inlet of the dam, it has not been shown to have a significant effect on the stress increa.

New Joint Roughness Coefficient and Shear Strength Criterion Based on Experimental Verification of Standard Roughness Profile (표준 거칠기 단면의 실험적 검증에 의한 새로운 거칠기 계수 및 전단강도 기준식)

  • Jang, Hyun-Sic;Sim, Min-Yong;Jang, Bo-An
    • The Journal of Engineering Geology
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    • v.31 no.4
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    • pp.561-577
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    • 2021
  • The ten standard roughness profiles suggested by Barton and Choubey (1977) were extended to make three-dimensional (3D) joint models whose profiles were identical at any cross section. Replicas of joint models were produced using plaster of Paris, and direct shear tests were performed to verify the joint roughness coefficients (JRC) of the standard roughness profiles. Joint shear strengths measured by direct shear tests were compared with those predicted by the shear failure criterion suggested by Barton (1973) based on JRC, joint compressive strength (JCS), and joint basic friction angle (𝜙b). Shear strengths measured from joints of the first and fourth standard roughness profiles were close to predicted values; however, shear strengths measured from the other joint models were lower than predicted, the differences increasing as the roughness of joints increased. Back calculated values for JRC, JCS, and from the results of the direct shear tests show measured shear strengths were lower than predicted shear strengths because of the JRC values. New JRC were back calculated from the measured shear strength and named JRCm. Values of JRCm were lower than the JRC for the standard roughness profiles but show a strong linear relationship to JRC. Corrected JRCm values for the standard roughness profiles are provided and revised relationships between JRCm and JRC, and new shear strength criterion are suggested.