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Regulation of Development in Aspergillus nidulans and Aspergillus fumigatus

  • Yu, Jae-Hyuk
    • Mycobiology
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    • v.38 no.4
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    • pp.229-237
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    • 2010
  • Members of the genus Aspergillus are the most common fungi and all reproduce asexually by forming long chains of conidiospores (or conidia). The impact of various Aspergillus species on humans ranges from beneficial to harmful. For example, several species including Aspergillus oryzae and Aspergillus niger are used in industry for enzyme production and food processing. In contrast, Aspergillus flavus produce the most potent naturally present carcinogen aflatoxins, which contaminate various plant- and animal-based foods. Importantly, the opportunistic human pathogen Aspergillus fumigatus has become the most prevalent airborne fungal pathogen in developed countries, causing invasive aspergillosis in immunocompromised patients with a high mortality rate. A. fumigatus produces a massive number of small hydrophobic conidia as the primarymeans of dispersal, survival, genome-protection, and infecting hosts. Large-scale genome-wide expression studies can now be conducted due to completion of A. fumigatus genome sequencing. However, genomics becomes more powerful and informative when combined with genetics. We have been investigating the mechanisms underlying the regulation of asexual development (conidiation) and gliotoxin biosynthesis in A. fumigatus, primarily focusing on a characterization of key developmental regulators identified in the model fungus Aspergillus nidulans. In this review, I will summarize our current understanding of how conidiation in two aspergilli is regulated.

Morphology Evolution of Poly(L-lactic acid) (PLLA), Poly(ε-caprolactone) (PCL) and Polyethylene Oxide (PEO) Ternary Blend and Their Effects on Mechanical Properties for Bio Scaffold Applications (폴리락틱산, 폴리카프로락톤, 폴리에틸렌 옥사이드 삼성분계 블렌드의 형태학적 변화와 이들이 의료용 스캐폴더의 기계적 특성에 미치는 영향)

  • Ezzati, Peyman;Ghasemi, Ismaeil;Karrabi, Mohammad;Azizi, Hamed;Fortelny, Ivan
    • Polymer(Korea)
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    • v.38 no.4
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    • pp.449-456
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    • 2014
  • Ternary blends of poly(L-lactic acid) (PLLA), poly(${\varepsilon}$-caprolactone) (PCL) and polyethylene oxide (PEO) were produced with different concentrations of components via melt blending. By leaching the PEO from the samples by water, porous materials were obtained with potential application for bio scaffolds. Sample porosity was evaluated by calculating the ratio of porous scaffold density (${\rho}^*$) to the non-porous material density (${\rho}_s$). Highest porosity (51.42%) was related to the samples containing 50 wt%. of PEO. Scanning electron microscopy (SEM) studies showed the best porosity resulted by decreasing PLLA/PCL ratio at constant concentration of PEO. Crystallization behavior of the ternary blend samples was studied using differential scanning calorimetry (DSC). Results revealed that the crystallinity of PLLA was improved by addition of PEO and PCL to the samples. The porosity plays a key role in governing the compression properties. Mechanical properties are presented by Gibson-Ashby model.

Influence on centrifugal force control in a self-driven oil purifier

  • Jung, Ho-Yun;Kwon, Sun-Beom;Choi, Yoon-Hwan;Lee, Yeon-Won
    • Journal of Advanced Marine Engineering and Technology
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    • v.38 no.10
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    • pp.1251-1256
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    • 2014
  • The use of lubrication oil is of many purposes and one among them is to drive the engine mounted on a ship. Hence the supply of clean lubrication oil is important. And an oil purifier is one of key components in marine diesel engines. At present, the element type full-flow oil filter has been widely used for cleaning the engine oil. The self-driven centrifugal oil purifier is a device which is used to remove the impurities in lubrication oil using a jet flow. The flow characteristics and the physical behaviors of particles in this self-driven oil purifier were investigated numerically and the filtration efficiencies were evaluated. For calculations, a Computational Fluid Dynamics method is used and the Shear Stress Transport turbulence model has been adopted. The Multi Frames of Reference method is used to consider the rotating effect of the flows. The influence of centrifugal forcehas been numerically investigatedto improve filtration efficiency of tiny particles. As a result of this research, it was found that the particle filtration efficiency using the only center axis rotating and outer wall rotating system are higher than that of the fully rotating system in the self-driven oil purifier.

Field-Measurement-Based Received Power Analysis for Directional Beamforming Millimeter-Wave Systems: Effects of Beamwidth and Beam Misalignment

  • Lee, Juyul;Kim, Myung-Don;Park, Jae-Joon;Chong, Young Jun
    • ETRI Journal
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    • v.40 no.1
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    • pp.26-38
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    • 2018
  • To overcome considerable path loss in millimeter-wave propagation, high-gain directional beamforming is considered to be a key enabling technology for outdoor 5G mobile networks. Associated with beamforming, this paper investigates propagation power loss characteristics in two aspects. The first is beamwidth effects. Owing to the multipath receiving nature of mobile environments, it is expected that a narrower beamwidth antenna will capture fewer multipath signals, while increasing directivity gain. If we normalize the directivity gain, this narrow-beamwidth reception incurs an additional power loss compared to omnidirectional-antenna power reception. With measurement data collected in an urban area at 28 GHz and 38 GHz, we illustrate the amount of these additional propagation losses as a function of the half-power beamwidth. Secondly, we investigate power losses due to steering beam misalignment, as well as the measurement data. The results show that a small angle misalignment can cause a large power loss. Considering that most standard documents provide omnidirectional antenna path loss characteristics, these results are expected to contribute to mmWave mobile system designs.

Development of an Agricultural Data Middleware to Integrate Multiple Sensor Networks for an Farm Environment Monitoring System

  • Kim, Joonyong;Lee, Chungu;Kwon, Tae-Hyung;Park, Geonhwan;Rhee, Joong-Yong
    • Journal of Biosystems Engineering
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    • v.38 no.1
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    • pp.25-32
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    • 2013
  • Purpose: The objective of this study is to develop a data middleware for u-IT convergence in agricultural environment monitoring, which can support non-standard data interfaces and solve the compatibility problems of heterogenous sensor networks. Methods: Six factors with three different interfaces were chosen as target data among the environmental monitoring factors for crop cultivation. PostgresSQL and PostGIS were used for database and the data middleware was implemented by Python programming language. Based on hierarchical model design and key-value type table design, the data middleware was developed. For evaluation, 2,000 records of each data access interface were prepared. Results: Their execution times of File I/O interface, SQL interface and HTTP interface were 0.00951 s/record, 0.01967 s/record and 0.0401 s/record respectively. And there was no data loss. Conclusions: The data middleware integrated three heterogenous sensor networks with different data access interfaces.

Axial impact behavior of confined concrete filled square steel tubes using fiber reinforced polymer

  • Zhang, Yitian;Shan, Bo;Kang, Thomas H.K.;Xiao, Yan
    • Steel and Composite Structures
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    • v.38 no.2
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    • pp.165-176
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    • 2021
  • Existing research on confined concrete filled steel tubular (CCFT) columns has been mainly focused on static or cyclic loading. In this paper, square section CCFT and CFT columns were tested under both static and impact loading, using a 10,000 kN capacity compression test machine and a drop weight testing equipment. Research parameters included bonded and unbonded fiber reinforced polymer (FRP) wraps, with carbon, basalt and glass FRPs (or CFRP, BFRP, and GFRP), respectively. Time history curves for impact force and steel strain observed are discussed in detail. Experimental results show that the failure modes of specimens under impact testing were characterized by local buckling of the steel tube and cracking at the corners, for both CCFT and CFT columns, similar to those under static loading. For both static and impact loading, the FRP wraps could improve the behavior and increase the loading capacity. To analyze the dynamic behavior of the composite columns, a finite element, FE, model was established in LS-DYNA. A simplified method that is compared favorably with test results is also proposed to predict the impact load capacity of square CCFT columns.

A Practice of Reading to Learn Linking the Subject Learning (교과학습과 연계한 학습독서의 실제)

  • Song, Gi-Ho
    • Journal of Korean Library and Information Science Society
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    • v.38 no.1
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    • pp.423-441
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    • 2007
  • Reading abilities are the key for students' problem-solving, self-directed learning and lifelong competency. Reading to learn is usually created through resources-based learning or inquiry-based learning. This study shows a integrated cross-curriculum approach as a alternative method of the reading to learn and it is completed In collaboration with classroom teachers. In this study especially, the model for reading-based information problem solving is introduced as a specific learning strategy of a integrated cross-curriculum and team-teaching.

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A Method for Evaluating the Temperature Coefficient of a Compound Semiconductor Energy Gap by Infrared Imaging Technique (적외선 영상기법에 의한 화합물 반도체 에너지갭의 온도계수 측정 방법)

  • Kang, Seong-Jun
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.38 no.5
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    • pp.338-346
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    • 2001
  • An infrared imaging method in which direct measurement of energy gap variations can be achieved by digital image processing is proposed. This method allows economic and easy evaluation of the temperature coefficients of a semiconductor energy gap. The key components of the method are a polychromator, a computer equipped with a frame grabber and a variable temperature cryostat. Tentative experimentation conducted on LEC grown semi-insulating GaAs has resulted in a fairly good agreement with the theoretical model. This proposed method could be applicable for most compound semiconductors.

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All-IP Digital Convergence and Its Effect on the Evolution of the Media Industry (All-IP화 디지털융합 및 미디어산업의 진화 연구)

  • Chung, Suk-Kyun
    • Journal of Information Technology Applications and Management
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    • v.18 no.2
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    • pp.23-38
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    • 2011
  • The advance of All-IP digital convergence is now triggering fundamental changes in the media industry. This article analyzes the evolution of the media industry based on a value chain model, with a special emphasis placed on the impact of digital technology on the structure of media production, distribution, and consumption. As the Internet has evolved into an access channel for all forms of media, the boundaries of the media industry remain unclear and open thus enabling anyone to become a creator of media. Furthermore, the scope of media continues to become more dynamic as competition grows between older and more innovative forms of media. In this light, adapting to innovative technologies and more effectively meeting the needs of customers represent key factors for the continued evolution of the media.

"Dust, Ice, and Gas In Time" (DIGIT) Herschel observations of GSS30-IRS1

  • Je, Hyerin;Lee, Jeong-Eun
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.66.2-66.2
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    • 2013
  • As part of the DIGIT key program, we observed GSS30-IRS1, a Class I object located in Ophiuchus (d=125 pc), with Herschel-PACS. More than 70 lines were detected in 50-200 micron band including CO, OH, H2O, and [OI]. All lines, except for [OI], were detected only at the central spaxel of $9.4^{{\prime}{\prime}}{\times}9.4^{{\prime}{\prime}}$ while the [OI] emission is extended along the NE-SW direction. One interesting feature in GSS30-IRS1 is that the continuum is extended beyond PSF, unlike line emission. It suggests that the external heating is important in GSS30-IRS1. For detail analysis of line fluxes, we apply the non-LTE LVG model, RADEX as well as simple rotational diagrams. We also use the Monte Carlo radiative transfer package, RADMC-3D to understand the heating mechanism of dust grains around GSS30-IRS1. We will discuss about heating and cooling processes associated with GSS30-IRS1.

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