• Proceedings of the Korean Vacuum Society Conference
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• 2008.08a
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• pp.200-200
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• 2008

• 건강소식
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• v.34 no.5
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• pp.28-31
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• 2010

강화의 봄은 고려산에서 완성된다. 선분홍의 진달래가 산천을 물들였다. 한 번 바람이 스쳐 지나가면 고려산에는 선분홍의 붉은 꽃물결이 일렁인다. 고려산 붉은 기운이 강화의 바닷가 초지진에도 이어져 외세 침략에 목숨으로 항거했던 옛 역사가 붉은 진달래꽃으로 피어난다. 자연과 역사가 하나 되는 곳, 강화도에서 봄을 만끽해보자.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.11a
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• pp.993-994
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• 2010

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2011.06a
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• pp.975-976
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• 2011

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2011.06a
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• pp.1393-1394
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• 2011

• The Korean Journal of Food And Nutrition
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• v.26 no.3
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• pp.485-491
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• 2013

Rhodiola spp. and red ginseng have been used for food and medicinal applications in disease chemoprevention in many Asian countries. Increased oxidative stress by reactive oxygen species (ROS) has been proposed to be a major cause of muscle fatigue. The present study was designed to investigate the protective effects of a fermented hot-water extract mixture from Rhodiola sachalinensis and red ginseng (MFR) on cell damage and the antioxidant enzyme system in $H_2O_2$-induced oxidative stress in skeletal muscle cells. C2C12 myoblasts were treated with various concentrations of NFR (non-fermented Rhodiola sachalinensis extract), FR (fermented hot-water extract from Rhodiola sachalinensis) and MFR for up to 5 days after the standard induction of differentiation, followed by semi-quantitative RT-PCR. MFR treatment dose-dependently protected oxidative damage of C2C12 cells. The treatment with MFR also enhanced mRNA expressions of MyoD, Cu/Zn SOD, Mn-SOD and GPX up to 16%. These results indicate that MFR exerts an anti-oxidative effect through a mechanism (s) that may involve the up-regulation of antioxidant enzymes, which may be important for the cellular redox environment in muscle cells.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.377-382
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• 2010

국내에는 약 14,000개의 중 소규모의 저수지들이 있다. 최근에 이상기후로 인한 많은 강우가 발생하여 저수지들의 월류나 파이핑으로 인한 붕괴가 지속적으로 일어나고 있어 많은 인명 및 재산피해가 발생하고 있다. 특히 설계홍수량을 초과하는 월류로 인한 댐 붕괴 발생 시 피해규모가 크기 때문에 전국적으로 본포되어 있는 저수지들의 설계홍수량을 시급히 파악하여 저수지의 수문학적 안전성을 판단하고 설계홍수량이 작은 저수지의 경우 별도로 관리 할 수 있어야 한다. 하지만 기존에 저수지의 안전여부를 판단 할 수 있는 댐 붕괴 모의의 경우 많은 시간과 노력이 요구 되어 저수지의 안전여부를 보다 쉽고 빠르게 판단 할 수 있는 기준 마련이 시급히 필요하다. 본 연구에서는 보다 쉽고 빠르게 소규모저수지의 수문학적 안전성 평가를 할 수 있는 간편법에 대하여 연구 하였다. 연구 방법은 HEC-HMS을 이용한 댐 붕괴와 본 연구에서 제시한 간편법을 통하여 홍수량의 비교 검토 및 저수지의 수문학적 안전성을 평가를 하였다. HEC-HMS의 첨두홍수량은 빈도별 지속시간별 확률강우량을 이용하여 산정하였으며, 가능최대홍수량(PMF)은 실제호우전이법으로 산정한 가능최대강수량(PMP)을 이용하였다. 간편법의 첨두홍수량은 합리식과 통합형 강우강도식을 이용하여 산정하였고, 가능최대홍수량(PMF)은 Creager공식을 이용하여 산1)정하였다. 댐 붕괴의 경우 HEC-HMS에서는 댐 붕괴 모듈을 실행하여 모의를 하였고, 간편법의 댐 붕괴는 여수로의 한계 유출을 파악할 수 있는 위어공식을 이용하여 댐 붕괴 모의를 하였다. 마지막으로 산정된 첨두홍수량과 가능최대홍수량(PMF)을 작성된 수문학적 안전성 평가표에 기입하여 비교 분석하였다. 연구결과 HEC-HMS로 산정한 빈도별 첨두홍수량 가능최대홍수량(PMF)과 간편법으로 구한 빈도별 첨두 홍수량 가능최대홍수량(PMF)의 차이는 약 편차가 50%정도로 간편법으로 구한 첨두홍수량 가능최대홍수량(PMF)이 더 크게 산정되었다. 편차의 발생 이유는 본 연구에서 제시한 간편법의 경우 안전율을 고려한 경험공식을 사용하였기 때문이라고 판단되며, 간편법을 통한 소규모저수지의 수문학적 안전성 평가를 다른 대상지역의 소규모저수지에도 적용하여 보고 수문학적 평가방법이 올바르게 적용 될 수 있는지 확인이 필요하다고 판단된다.

• Journal of Life Science
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• v.20 no.5
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• pp.775-781
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• 2010

The antioxidant activities of hot water extracts from fresh, red and black garlic processed in low temperatures were compared. The chromaticity value of browning garlic was between that of fresh and black garlic. Red garlic was similar in browning intensity to fresh garlic. Also, total phenol, flavonoids, total pyruvate and thiosulfate contents were similar between fresh and black garlic. DPPH, ABTs, NO radical scavenging activity and reducing power of red garlic were significantly higher than fresh garlic, but lower than those of black garlic. $\alpha$-Glucosidase inhibitory activity in red garlic was similar to that in black garlic. Antioxidant activities of red garlic were higher than fresh garlic but lower than black garlic, and it was confirmed that antioxidant activity by production of browning material through the thermal process was the main parameter of the biological activity in the aged red garlic.

• The Journal of the Petrological Society of Korea
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• v.3 no.1
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• pp.76-93
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• 1994

The Precambrian Hongjesa granite is lithologically zoned from biotite granite in central part to biotite-muscovite granite towards the margin. The X_{Fe}$ (=Fe/(Fe+Mg)) value and the aluminum saturation index of biotite systematically vary as a function of mineral assemblage, and are positively related with those of bulk rock. This relationship as well as the lithological zoning are attributed to the fractional crystallization of the Hongjesa granitic magma. The trace element data corroborate that biotite-muscovite granite is more fractionated than biotite granite. The evolution of the Hongjesa granite is elucidated by using the AFM liquidus topology, where A=$Al_2O_3-CaO-Na_2O-K_2O$; F=FeO+MnO; and M=MgO. At an early magmatic stage where biotite is the only ferromagnesian mineral to crystallize, the X_{Fe}$ value and the alumina content of granitic magma continuously increase.. Muscovite subsequently crystallizes with biotite along the biotitemuscovite cotectic curve where biotite-muscovite granite forms. Local enrichments in Mn and B further crystallize garnet and tourmaline, respectively. The unique zonal pattern characterized by the occurrence of the evolved biotite-muscovite granite at the margin may be accounted for by the passive stoping during the emplacement of the Hongjesa granite. This emplacement may have occurred in continental collision environment, according to the tectonic discrimination diagram using major element chemistry.

• Food Science and Preservation
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• v.11 no.1
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• pp.63-70
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• 2004

The antimicrobial substances from Rhodiola sachalinensis were extncted, isolated and identified. The highest level of antimicrobial activity and its yield were obtained in methanol extract. The minimum inhibition concentrations of the methanol extract were 500 $\mu\textrm{g}$mL on agar plate and 100 $\mu\textrm{g}$mL in broth media for four gram positive and four gram negative microbials. The methanol extract was fractionated by n-hexane, chloroform, ethyl ether, ethyl acetate, and butanol, orderly. The separate was developed on the TLC plate with different solvent system ratio of chloroform and methanol. Nine substances were isolated from chloroform and methanol mixture(9:1, v/v). Among them, three isolates showed antimicrobial activity. Three substances separated by HPLC were identified by GC/MS(EI) spectrum and $^1$H, /sup13/C-NMR spectrum. They were gallic acid, (-)-epicatechin and kaempferol. The antimicrobial activities of each substances were shown gallic acid, (-)-epicatechin, kaempferol orderly.