• Applied Microscopy
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• v.41 no.1
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• pp.21-29
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• 2011

Balneotherapy has been widely used for the treatment of skin diseases in the world. The purpose of this study was to determine the bath effect of the alkaline reduced spring water with the properties of high pH and low oxidation reduction potential (ORP) on the skin injury induced by ultra violet (UV) irradiation. For this purpose, hairless mice were irradiated with UV-B to cause skin injury, and individually taken a bath in spring water (experimental group) and tap water (control group) once a day for 40 min during 21 days. We observed histological changes of the back skin through macro- and microscopic methods compared to the control group. We found that skin injury of the experimental group was more quickly recovered than that of the control group. Under the light microscope, the experimental group showed that epidermal thickening (p<0.01) and the mast cell activation (p<0.001) were lower compared with the control group, in addition infiltration of inflammatory cells and degranulation of mast cells were less observed. These results suggest that regular bath in the spring water with the properties of high pH and low ORP has a positive effect on the skin injury induced by UV irradiation.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.4
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• pp.351-359
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• 2015

Acute and chronic ultraviolet (UV) irradiation triggers severe skin photoaging processes, which directly disrupt the normal three-dimensional integrity of skin. UV light stimulates the expression of matrix metalloproteinases (MMPs) which degrade constituents of extracellular matrix (ECM) proteins. These MMPs reduce collagen synthesis and decrease skin elasticity and integrity, resulting in wrinkle formation. In this study, we identified Rosa multiflora hip extract (RME) as an effective anti-photoaging ingredient. First, cell proliferation activity of RME was verified using Hs68 human dermal fibroblast cell line. RME downregulated MMPs expression through the inhibition of activator protein (AP)-1. In addition, type I and IV collagen expressions were increased with RME treatment and UVB-induced inflammatory responses were also reduced after RME treatment. In conclusion, R. multiflora hip extract may effectively improve UVB-induced skin aging and wrinkle formation which may provide as an anti-aging, anti-wrinkle, and anti-inflammation ingredient in cosmetic industry.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2003.11a
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• pp.251-254
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• 2003

'UNEP Global Environment Outlook 2000'의 자료에 의하면, 향후 1000년에 가장 심각한 환경문제는 "지구온난화" 였다. $CO_2$ 농도 증가 등으로 인한 기후변화로 지난 100년간 전 세계적으로 기온은 평균 0.3~0.6$^{\circ}C$ 상승, 해수면은 평균 25 cm 내외 상승, 프레온가스 등으로 인하여 성층권의 오존층이 파괴되어 피부암과 안질환이 급증하고 면역기능이 저하되며, 현종 식물종 8%, 조류 11%, 어류 5%, 포유류 14%가 멸종위기에 처하는 등 생물다양성의 감소, 내분비계 장애물질(환경호르몬) 증가로 유해화학물질에 더욱 노출되고 있다. (중략)

• Science of Emotion and Sensibility
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• v.1 no.2
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• pp.65-73
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• 1998

본 연구는 여름철에 수행된 체감실험 결과이다. 연구의 목적은 함국인을 대상으로 여름철 체감실험을 통해 SET*(PMV)와 상관관계를 규명하고, ASHRAE Standard 55-74의 쾌적영역과 한국인의 쾌적영역을 비교 검토한는 것이다. 따라서 한국인에 대하여 생리 및 심리적인 접근방법을 통해 냉방시 온열쾌적감을 분석하여, 온열환경지표(PMV, SET*)의 적용가능성을 검토하였다. 또한 청년 및 고령자에 대하여 각각 쾌적영역을 제시하였다. 냉방시 체감실험결과는 다음과 같다. 1. 청년층의 중립 SET*(TSV=0)는 26.4$^{\circ}C$이었지만, 고령자의 경우는 26.9$^{\circ}C$ 이었다. 2. 청년과 고령자의 발한은 평균피부온도 34$^{\circ}C$ 근처에서 급격하게 상승하였다. 3. 청년층의 온열적 중립영역은 SET* 25.4~27.5$^{\circ}C$(0.20$0^{\circ}C$(0.43

• Applied Microscopy
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• v.32 no.2
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• pp.121-129
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• 2002

The structure of integumentary epidermis is studied in the bastard halibut, Paralichthys olivaceus based on the light and transmission electron microscope. Epidermal layer consists of supporting cells, unicellular glands and accessory cells. The supporting cells were classified into superficial cell, intermediated cell and basal cell. Superficial cell of epidermal layer is squamous or cuboidal and the surface is covered with numerous microridges. The supporting cells are connected to another cell with membrane interdigitations and desmosmes. And tonofilaments are developed in the cortical cytoplasm. Gland cells are classified into mucous cell and club cell. By the histochemical studies of the epidermal secretions the mucous materials are identified as neutral polysaccharides. Club cell has numerous vacuoles and microfilaments in the cytoplasm. Also chloride cells are observed in the epidermis, it cytoplasm is occupied numerous mitochondria.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.25 no.1
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• pp.37-54
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• 1999

Planarized SiO$_2$ particles were prepared by two-step reduction method of making much smaller particles, micron-sized ones, to improve spreadability, adherence, and smoothness. Various pigments known as flaky extender usually have terrace layers on their surfaces, but SiO$_2$ Particles in this study exhibit a smooth surface structure. These single SiO$_2$ particles were used for core particles to prepare the composite particles coated with ultra fine TiO$_2$ particles by a homogeneous precipitation method. The thickness and the morphology of the deposited TiO$_2$ layer could be altered by adjusting the reactant concentrations, reaction time and temperature. The characteristics of SiO$_2$/TiO$_2$composite in the field of color cosmetics is to give a UV-cut effect and to enhance the chroma of human skin color, one of optical properties.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2011.11a
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• pp.30-30
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• 2011

산업화 과정에 방출된 할로겐 화합물 및 프레온 가스가 오존층을 파괴하면서 많은 양의 자외선이 지표에 도달하여 생태계에 적지 않은 영향을 끼치고 있다. 자외선은 살균, 소독작용 및 Vitamin D 합성을 위해 생명체에 필수적이지만 과다할 경우 색소침착, 피부노화, 피부암 발생, 백내장의 증가, 면역기능저하 등의 피해를 준다. 자외선은 파장 영역에 따라 UV-A(장파장 자외선), UV-B(중파장 자외선)및 UV-C(단파장 자외선)으로 나뉜다. 이 중 인체에 가장 유해한 것으로 알려진 단파장의 UV-C는 파장이 짧아 침투력이 미약해 오존층과 성층권에서 대부분 흡수되므로 생물학적으로 큰 의미는 없다. 그러나 자외선 중 UV-B와 UV-A 영역의 자외선은 인체에 영향을 가장 많이 미치므로 이들 영역의 자외선을 차단하는 것이 필요하다. Vitamin C는 아스코르브산(ascorbic acid)이라고도 불리며 미백효과, 주름 개선, 자외선 차단 및 항산화 작용을 하지만 섬유가공 시 Vitamin C는 쉽게 산화되며 세탁 내구성이 떨어지기 때문에 가교제를 필요로 한다. Vitamin C를 이용하여 자외선 차단성 섬유제품을 개발하기 위해, 포름알데히드를 유리하지 않는 폴리카르복시산 가교제 중 하나인 Citric Acid(CA)를 사용하여 고온에서 면직물에 처리했을 때 에스테르 형 가교를 형성하여 내세탁성을 가질 수 있었다. 자외선 차단 효과를 알아보기 위하여 KS K 0850 섬유제품의 자외선 차단율 및 차단지수 시험방법으로 평가하였다.

• Journal of the Korean Society of Radiology
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• v.84 no.5
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• pp.1134-1139
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• 2023

Merkel cell carcinoma (MCC) is a rare malignant cutaneous tumor primarily located in the head and neck. We report the imaging features of pathologically confirmed MCC in the trunk. On US, MCC showed heterogeneous echogenicity with perpendicular hypoechoic linear bands that resembled "columns of smoke" in the skin and subcutaneous layers as well as prominent vascularity. On MRI, the tumor showed hypointensity on T1-weighted images and hyperintensity on proton density and T2-weighted images with linear low-signal bands in the skin and subcutaneous layers as well as intense enhancement on T1-enhanced images. Although MCC has nonspecific imaging features, these characteristics may be helpful for the early diagnosis of this disease.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.158-165
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• 2017

The purpose of this study is to provide basic data for increased understanding of detailed customer needs by age group, and also to improve customer satisfaction. The survey was conducted from August $30^{th}$ to September $15^{th}$, 2017. The poll was conducted with 302 persons aged from 20's to 50's by using convenience-sampling method and self-administration method for survey. The results were analyzed by frequencies, independent sample t-test, Pearson correlations, and through multiple regression analysis. The study results are briefly summarized as follows. First, the overall age group's interest of hand's health was robustly high. Second, in the 20s and 30s age groups hand care interest and self-hand care (r=.284, p<.01) increased with improved hand health condition. In the 40s and 50s age groups there were positive correlations between hand health condition and Information recognition(${\beta}=.246$, p<.1), Product use(${\beta}=.312$, p<.05), and Professional Hand Care(${\beta}=.354$, p<.000). This study indicates that hand care concern and management behaviors change with age. Therefore, further research and more specific follow-up are required for improvement of the awareness of healthy hands.

• Applied Microscopy
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• v.41 no.2
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• pp.129-137
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• 2011

The aim of this study was to evaluate the inhibitory effect of nude pack containing black tea water extract (NPBT) on skin wrinkle formation in hairless mice. Skin wrinkles were induced by UVB irradiation to the backs of hairless mice for 5 weeks. And at the same time, NPBT was applied topically. Wrinkle formation, histological changes, expression of matrix metalloproteinase-3 (MMP-3) and protein activities of MMP-2 and MMP-9 were observed or analyzed. Wrinkles for the control group were formed as a pattern of deep furrows and thick crests. Whereas wrinkles for the NPBT treated group were formed as a pattern of shallow furrows and thin crests, and their wrinkle areas were significantly (p<0.001) lower than the control group. Collagen fibers were arranged irregularly and sparse in density and some elastic fibers were degenerated in the control group, while they were almost intact in the NPBT treated group. MMP-3 mRNA expression in the control group was significantly (p<0.001) higher than the normal group, and that of NPBT treated group was significantly (p<0.001) lower than the control group. The NPBT treated group showed remarkably lower protein activities of MMP-2 and MMP-9 than the control group. NPBT could have a considerable inhibitory effect on skin wrinkle formation in hairless mice.