• Title/Summary/Keyword: 표적기술

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Differential Response to Joint Attention in Children with Autism Spectrum Disorder Depending on the Level of Attentional Cues (주의 단서 수준에 따른 자폐 범주성 장애 아동의 공동주의집중 반응 연구)

  • Yoo, Ga Eul
    • Journal of Music and Human Behavior
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    • v.11 no.1
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    • pp.21-37
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    • 2014
  • The significant role of joint attention in the development of children with autism spectrum disorder (ASD) has highlighted the importance of early intervention. With the emphasis on the effective cueing and reinforcer for orienting to social stimuli in improving responding to joint attention (RJA) of children with ASD, the use of musical cue was hypothesized. This study aimed to examine the occurrence of RJA behaviors depending on the attentional cue, which differed in the level of information and type of auditory modality. Nine children with ASD participated in this study. The use of eight different joint attention cues were analyzed in terms of the frequency and accuracy of RJA behaviors elicited. The results of the study showed that RJA behaviors occurred more frequently with musical cues than with verbal cues and the mean accuracy rate of RJA was higher with musical cues (p = .047). Musically delivered eliciting and directing cues accompanied with pointing elicited the highest attentional shift and RJA accuracy. The significant increases in RJA with the use of musical cues indicated that incorporating musical elements into an attentional cue may provide more accurate cue information, enough to improve RJA behaviors of children with autism.

A Study on the Honesty Ethical Consciousness of Koreans and the Mission of Korean Churches (한국인의 정직윤리의식과 한국교회의 역할에 대한 연구)

  • Ahn, Jong Bae
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.4
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    • pp.67-78
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    • 2020
  • Honesty is an attribute of God, and the Bible says that God is pleased, praises, and blesses honest people. However, false and hypocrisy is overflowing and honesty is being weakened in Korean society and the church. In this regard, we need to understand the level of honesty and ethical consciousness of youth and adults (workers) in Korea, and how to spread honesty in Korean society in order for the Korean church to restore its essence and play the role of light and salt in the world. To this end, We analyzed the honest ethical consciousness of Korean youth and adults (workers) by using the results of the Korean Honest Index survey conducted by the researchers at the Ethics Center of the Transparent Society Movement Headquarters of the Heungsadan in 2019. In addition, through Focus Group Interview (FGI) of 12 pastors who are practicing the honesty movement in the Korean church, we analyzed pastors' opinions on what the Korean church should do and what role it should play in order to raise the honesty ethical consciousness of Korean society. We hope that it will be an opportunity to recognize the seriousness of the honest and ethical consciousness of Korean society, and to take an active role in helping the Korean church return to the spirit of Koramdeo and spread the honest kingdom and righteousness of God in Korean society through this study.

VANET Privacy Assurance Architecture Design (VANET 프라이버시 보장 아키텍처 설계)

  • Park, Su-min;Hong, Man-pyo;Shon, Tae-shik;Kwak, Jin
    • Journal of Internet Computing and Services
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    • v.17 no.6
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    • pp.81-91
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    • 2016
  • VANET is one of the most developed technologies many people have considered a technology for the next generation. It basically utilizes the wireless technology and it can be used for measuring the speed of the vehicle, the location and even traffic control. With sharing those information, VANET can offer Cooperative ITS which can make a solution for a variety of traffic issues. In this way, safety for drivers, efficiency and mobility can be increased with VANET but data between vehicles or between vehicle and infrastructure are included with private information. Therefore alternatives are necessary to secure privacy. If there is no alternative for privacy, it can not only cause some problems about identification information but also it allows attackers to get location tracking and makes a target. Besides, people's lives or property can be dangerous because of sending wrong information or forgery. In addition to this, it is possible to be information stealing by attacker's impersonation or private information exposure through eavesdropping in communication environment. Therefore, in this paper we propose Privacy Assurance Architecture for VANET to ensure privacy from these threats.

Consumer Characteristics Related with Choice of Eco-Friendly Functional Food (생태 친화적 기능성식품 선택과 관련된 소비자 특성 분석)

  • Park, Myeong-Eun;Nam, Jung-Mi;You, So-Ye
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.8
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    • pp.456-471
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    • 2019
  • Consumers' growing interest in the environment has recently led them to recognize the importance of their dietary life and sustainable consumption. Thus, there is an increasing necessity to identify consumers' response on the relationship between the consumption of functional food and their interest in helping environment. This research was conducted to analyze consumers' behaviors as related to Spirulina, an eco-friendly functional food brand, by subdividing markets according to consumers' food lifestyle. The results showed that consumers were categorized into 3 types (high involvement in diet, pursuit of safety in diet, and pursuit of convenience in diet), and there was a significant difference in the consumption behaviors of the functional food according to the 3 types. Their positive attitude towards functional food and interest in the environment led to changes of their actual purchasing behavior by increased purchase of Spirulina. Also, consumers who displayed high environmental involvement showed a more favorable attitude towards functional food. Therefore, to expand the market of eco-friendly functional food, it is necessary to subdivide the market and target the consumers who are highly involved with protecting the environment, and to execute marketing strategies for eco-friendly products, in order to increase the consumers' awareness about eco-friendly functional food.

Key Structural Features of PigCD45RO as an Essential Regulator of T-cell Antigen Receptor Signaling (T-세포 항원 수용체 매개 신호전달 조절자로서 돼지 CD45RO 구조특성)

  • Chai, Han-Ha;Lim, Dajeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.9
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    • pp.211-226
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    • 2019
  • Pig CD45, the leukocyte common antigen, is encoded by the PTPRC gene and CD45 is a T cell-type specific tyrosine phosphatase with alternative splicing of its exons. The CD45 is a coordinated regulator of T cell antigen receptor (TCR) signal transduction achieved by dephosphorylating the phosphotyrosine of its substances, including $CD3{\zeta}$ chain of TCR, Lck, Fyn, and Zap-70 kinase. A dysregulation of CD45 is associated with a multitude of immune disease and has been a target for immuno-drug discovery. To characterize its key structural features with the effects of regulating TCR signaling, this study predicted the unknown structure of pig CD45RO (the smallest isoform) and the complex structure bound to the ITAM (REEpYDV) of $CD3{\zeta}$ chain via homology modeling and docking the peptide, based on the known human CD45 structures. These features were integrated into the structural plasticity of extracellular domains and functional KNRY and PTP signature motifs (the role of a narrow entrance into ITAM binding site) of the tyrosine phosphatase domains in a cytoplasmic region from pig CD45RO. This contributes to the selective recognition of phosphotyrosine from its substrates by adjusting the structural stability and binding affinity of the complex. The characterized features of pigCD45RO can be applied in virtual screening of the T-cell specific immunomodulator.

Effects of Piperine on Insulin Resistance and Lipid Accumulation in Palmitate-treated HepG2 Cells (Palmitate처리된 인간 간세포주 HepG2 세포에서 piperine의 지질 축적과 인슐린 저항성 기전에 대한 연구)

  • Jung, Hee Jin;Bang, EunJin;Jeong, Seong Ho;Kim, Byeong Moo;Chung, Hae Young
    • Journal of Life Science
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    • v.29 no.9
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    • pp.964-971
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    • 2019
  • Hepatic lipid accumulation and insulin resistance increases in patients with non-alcoholic fatty liver disease. Piperine is a major compound found in black pepper (Piper nigrum) and long pepper (P. longum). Piperine has been used in fine chemical for its anti-cancer, anti-obesity, anti-diabetic, anti-inflammatory and anti-oxidant properties. However, the signaling-based mechanism of piperine and its role as an inhibitor of lipogenesis and insulin resistance in human hepatocyte cells remains ill-defined. In the present study, we explored the effects of piperine on lipid accumulation and insulin resistance, and explored the potential underlying molecular mechanisms in palmitate-treated HepG2 cells. Piperine treatment resulted in a significant reduction of triglyceride content. Furthermore, piperine treatment decreased palmitate-treated intracellular lipid deposition by inhibiting the lipogenic target genes, sterol-regulatory-element-binding protein 1c (SREBP-1c) and fatty acid synthase (FAS); whereas the expression of carnitine palmitoyl transferase (CPT-1) and phosphorylation of acetyl coenzyme A carboxylase (ACC) gene involved in fatty acid oxidation was increased. Moreover, piperine also inhibited the phosphorylation of insulin receptor substrate (IRS)-1 (Ser307). Piperine treatment modulated palmitate-treated lipid accumulation and insulin resistance in HepG2 cells with concomitant reduction of lipogenic target genes, such as SREBP-1 and FAS, and induction of CPT-1-ACC and phosphorylation of IRS-1 (Tyr632)-Akt pathways. Therefore, piperine represents a promising treatment for the prevention of lipid accumulation and insulin resistance.

A Study on Deep Learning based Aerial Vehicle Classification for Armament Selection (무장 선택을 위한 딥러닝 기반의 비행체 식별 기법 연구)

  • Eunyoung, Cha;Jeongchang, Kim
    • Journal of Broadcast Engineering
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    • v.27 no.6
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    • pp.936-939
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    • 2022
  • As air combat system technologies developed in recent years, the development of air defense systems is required. In the operating concept of the anti-aircraft defense system, selecting an appropriate armament for the target is one of the system's capabilities in efficiently responding to threats using limited anti-aircraft power. Much of the flying threat identification relies on the operator's visual identification. However, there are many limitations in visually discriminating a flying object maneuvering high speed from a distance. In addition, as the demand for unmanned and intelligent weapon systems on the modern battlefield increases, it is essential to develop a technology that automatically identifies and classifies the aircraft instead of the operator's visual identification. Although some examples of weapon system identification with deep learning-based models by collecting video data for tanks and warships have been presented, aerial vehicle identification is still lacking. Therefore, in this paper, we present a model for classifying fighters, helicopters, and drones using a convolutional neural network model and analyze the performance of the presented model.

Application of Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry (Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry의 활용)

  • Pil Seung KWON
    • Korean Journal of Clinical Laboratory Science
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    • v.55 no.4
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    • pp.244-252
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    • 2023
  • The timeliness and accuracy of test results are crucial factors for clinicians to decide and promptly administer effective and targeted antimicrobial therapy, especially in life-threatening infections or when vital organs and functions, such as sight, are at risk. Further research is needed to refine and optimize matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)-based assays to obtain accurate and reliable results in the shortest time possible. MALDI-TOF MS-based bacterial identification focuses primarily on techniques for isolating and purifying pathogens from clinical samples, the expansion of spectral libraries, and the upgrading of software. As technology advances, many MALDI-based microbial identification databases and systems have been licensed and put into clinical use. Nevertheless, it is still necessary to develop MALDI-TOF MS-based antimicrobial-resistance analysis for comprehensive clinical microbiology characterization. The important applications of MALDI-TOF MS in clinical research include specific application categories, common analytes, main methods, limitations, and solutions. In order to utilize clinical microbiology laboratories, it is essential to secure expertise through education and training of clinical laboratory scientists, and database construction and experience must be maximized. In the future, MALDI-TOF mass spectrometry is expected to be applied in various fields through the use of more powerful databases.

Evaluation method for interoperability of weapon systems applying natural language processing techniques (자연어처리 기법을 적용한 무기체계의 상호운용성 평가방법)

  • Yong-Gyun Kim;Dong-Hyen Lee
    • Journal of The Korean Institute of Defense Technology
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    • v.5 no.3
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    • pp.8-17
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    • 2023
  • The current weapon system is operated as a complex weapon system with various standards and protocols applied, so there is a risk of failure in smooth information exchange during combined and joint operations on the battlefield. The interoperability of weapon systems to carry out precise strikes on key targets through rapid situational judgment between weapon systems is a key element in the conduct of war. Since the Korean military went into service, there has been a need to change the configuration and improve performance of a large number of software and hardware, but there is no verification system for the impact on interoperability, and there are no related test tools and facilities. In addition, during combined and joint training, errors frequently occur during use after arbitrarily changing the detailed operation method and software of the weapon/power support system. Therefore, periodic verification of interoperability between weapon systems is necessary. To solve this problem, rather than having people schedule an evaluation period and conduct the evaluation once, AI should continuously evaluate the interoperability between weapons and power support systems 24 hours a day to advance warfighting capabilities. To solve these problems, To this end, preliminary research was conducted to improve defense interoperability capabilities by applying natural language processing techniques (①Word2Vec model, ②FastText model, ③Swivel model) (using published algorithms and source code). Based on the results of this experiment, we would like to present a methodology (automated evaluation of interoperability requirements evaluation / level measurement through natural language processing model) to implement an automated defense interoperability evaluation tool without relying on humans.

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Preference Analysis of General Adult on the Forest and Forest Road for the Development of Forest Therapy Program (산림치유 프로그램 개발을 위한 일반 성인의 숲과 숲길의 선호도 분석)

  • Kim, Youn-Hee;Kim, Dong-Jun;Yeoun, Pyung-Sik;Choi, Byung-Jin
    • Korean Journal of Environment and Ecology
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    • v.28 no.5
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    • pp.597-606
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    • 2014
  • The preference of general adult on the forest and forest road was surveyed and analyzed for the development of forest therapy program. This study was conducted for the purpose of providing a basis for the development of more targeted-and differentiated-forest therapy program by analyzing the preference of general adult on the forest and forest road from 19 April 2014 to 30 June 2014 through on-line survey. The sample group of 613 adults has been used in practical analysis. Using SPSS 21.0, We looked at the preference differences of the forest and forest road according to the demographic characteristics(sex, age, education level, occupation and monthly income) through descriptive statistics analysis, frequency analysis, cross tabulation analysis, multiple response analysis. The seasonal preference was spring, autumn, any season, summer, winter in order and there was a significant difference according to one's sex, age, occupation and monthly income. There was a significant difference in the configuration of forest according to one's monthly income. The favorite type of forest as a place of forest healing program was natural recreational forest, healing forest, urban forest, park, school forest in order. There was no significant difference in the favorite forest type regarding to the distance to the healing place from one's residence in all cases. There was a significant difference in the type of forest according to one's monthly income. The most favorite configuration of forest road was gentle sloped road. Once walking into the forest for the purpose of healing, the favorite forest road length was 1.5~3 km, less then 1.5 km, more than 3 km in order and there was a significant difference in preference according to one's sex, age, education level and monthly income. We believe that the healing program should be differentiated from the general form of it according to one's sex, age, education level, occupation and monthly income as a result of this investigation of preference of general adult on the forest and forest road for the development of forest therapy program. In particular, we believe that the differentiated program should be offered according to one's age. We expect this analysis to be used as a basis for the development of forest therapy program.