• Title/Summary/Keyword: 표면조직화

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The effects of properties and interactions of surface molecules in antigen presenting cells on T cell activation (인공 항원제시세포의 표면 분자의 특성 및 상호작용이 T 세포 활성화에 미치는 영향)

  • Min, Youngsil;Kang, Yoon Joong
    • Journal of Convergence for Information Technology
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    • v.10 no.6
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    • pp.164-176
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    • 2020
  • Efficient production of antigen specific cytotoxic T cells is critical for appropriate adoptive immune response. In vitro culture and expansion of human T lymphocyte clones are very sophisticated and subtle procedure in immune cell therapy and hard to control. Therefore, many groups devoted their efforts to manipulate artificial antigen presenting cells (aAPCs) that can induce T cell activation and clonal expansion. To mimicking of natural antigen-presenting cells, aAPCs encompass basic signal molecules required for T cell activation: MHC:antigen complexes, co-stimulatory molecules and soluble immune modulating molecules. Orchestrated organization of these molecules is important for efficient T cell activation. Here, we discuss how those molecules have been incorporated in several aAPC models, but also how physical properties od aAPC are important for interaction with T cells.

Ultimate Heterogeneous Integration Technology for Super-Chip (슈퍼 칩 구현을 위한 헤테로집적화 기술)

  • Lee, Kang-Wook
    • Journal of the Microelectronics and Packaging Society
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    • v.17 no.4
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    • pp.1-9
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    • 2010
  • Three-dimensional (3-D) integration is an emerging technology, which vertically stacks and interconnects multiple materials, technologies, and functional components such as processor, memory, sensors, logic, analog, and power ICs into one stacked chip to form highly integrated micro-nano systems. Since CMOS device scaling has stalled, 3D integration technology allows extending Moore's law to ever high density, higher functionality, higher performance, and more diversed materials and devices to be integrated with lower cost. The potential benefits of 3D integration can vary depending on approach; increased multifunctionality, increased performance, increased data bandwidth, reduced power, small form factor, reduced packaging volume, increased yield and reliability, flexible heterogeneous integration, and reduced overall costs. It is expected that the semiconductor industry's paradiam will be shift to a new industry-fusing technology era that will offer tremendous global opportunities for expanded use of 3D based technologies in highly integrated systems. Anticipated applications start with memory, handheld devices, and high-performance computers and extend to high-density multifunctional heterogeneous integration of IT-NT-BT systems. This paper attempts to introduce new 3D integration technologies of the chip self-assembling stacking and 3D heterogeneous opto-electronics integration for realizng the super-chip.

Multiple Texture Image Recognition with Unsupervised Block-based Clustering (비교사 블록-기반 군집에 의한 다중 텍스쳐 영상 인식)

  • Lee, Woo-Beom;Kim, Wook-Hyun
    • The KIPS Transactions:PartB
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    • v.9B no.3
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    • pp.327-336
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    • 2002
  • Texture analysis is an important technique in many image understanding areas, such as perception of surface, object, shape and depth. But the previous works are intend to the issue of only texture segment, that is not capable of acquiring recognition information. No unsupervised method is basased on the recognition of texture in image. we propose a novel approach for efficient texture image analysis that uses unsupervised learning schemes for the texture recognition. The self-organization neural network for multiple texture image identification is based on block-based clustering and merging. The texture features used are the angle and magnitude in orientation-field that might be different from the sample textures. In order to show the performance of the proposed system, After we have attempted to build a various texture images. The final segmentation is achieved by using efficient edge detection algorithm applying to block-based dilation. The experimental results show that the performance of the system Is very successful.

The Texturization Properties of Textured Extrudate made by a Mixture of Rice Flour and Isolated Soybean Protein (쌀과 분리대두단백 혼합에 따른 조직화 특성)

  • Han, Ouk;Park, Yong-Ho;Lee, Sang-Hyo;Lee, Hyun-Yu;Min, Byong-Lyoung
    • Korean Journal of Food Science and Technology
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    • v.21 no.6
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    • pp.780-787
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    • 1989
  • The texturization properties of extrudate from isolated soybean protein and rice flour by extrusion cooking were investigated. The addition of up to 30% rice flur to isolated soy proetin could give more tenderness to the texturized extrudate. As the rice flour content increased, die temperature, nitrogen solubility index, and integrity index were decreased slightly with lower chewiness and gumminess. The water content of final extrudate was increased as the addition of rice flour increased, while density was maintained without variation, and rehydration ratio was decreased. The distribution of pressure profile during extrusion were in the range of $15-100kg/cm^3$. As the addition of rice flour increased, scanning electron micrographs demonstrated the gelatinized surface structure of rice starch and the increased air cell size of the testurized extrudate.

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Double Texturing of Glass Substrate and ZnO : Al Transparent Electrode Surfaces for High Performance Thin Film Solar Cells (고성능 박막태양전지를 위한 유리 기판 및 산화 아연 투명 전극의 2중 구조 표면 조직화 공정 연구)

  • Kang, Dong-Won
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.8
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    • pp.1230-1235
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    • 2017
  • We studied surface texture-etching of glass substrate by using reactive ion etching process with various working pressure (0.7~9.0 mT). With the increase in the pressure, a haze parameter, which means diffusive transmittance/total transmittance, was increased in overall wavelength regions, as measured by spectrophotometer. Also, atomic force microscopy (AFM) study also showed that the surface topography transformed from V-shaped, keen surface to U-shaped, flattened surface, which is beneficial for nanocrystalline silicon semiconductor growth with suppressing defective crack formation. The texture-etched ZnO:Al combined with textured glass exhibited pronounced haze properties that showed 60~90 % in overall spectral wavelength regions. This promising optical properties of double textured, transparent conducting substrate can be widely applied in silicon thin film photovoltaics and other optoelectronic devices.

Interactive Tree Modeling Method Suitable for Real-time Systems (실시간 시스템에 적합한 인터렉티브 나무 모델링 기법)

  • Kim, Jin-Mo;Cho, Hyung-Je
    • Proceedings of the Korean Information Science Society Conference
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    • 2011.06a
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    • pp.426-429
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    • 2011
  • 광범위한 지형을 배경으로 하는 게임과 같은 실시간 시뮬레이션 시스템에서 사실적 표현을 높이는 중요한 요소 중 하나가 나무와 같은 자연물 표현이다. 하지만 시스템에 적합한 나무 모델을 매번 새롭게 제작하고 표현하는 일은 다소 어려움이 따른다. 본 연구는 이러한 문제를 해결하기 위하여 실시간 시스템에 적합한 다양하고 사실적인 나무를 모델링하는 방법을 설계한다. 이는 프랙탈 기반의 재귀적 계층 구조를 바탕으로 가지 성장의 자기조직화 처리를 결합하여 나무 성장 과정을 단순화시킴으로써 실시간 시스템에서 직관적이고 효율적으로 활용가능하게 한다. 또한 다양한 나무 모델을 자연스럽게 생성할 수 있도록 인터렉티브 제어 요소를 정의함은 물론 실시간 시스템 내 많은 수의 복잡한 나무 모델을 효율적으로 렌더링하기 위한 GPU를 기반으로 한 가지 표면에 대한 LOD 설정과 인스턴싱 방법을 추가하여 그 결과를 함께 보인다.

Gel Type Formulation Utilizing Polymer-Surfactant Interaction (폴리머와 계면활성제의 상호작용을 이용한 젤타입 제형의 제조)

  • Kim, Dong-Joo;Kang, Tae-Jun;Lee, Cheon-Koo;Lee, Jung-No
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.33 no.1 s.60
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    • pp.7-10
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    • 2007
  • The interaction between polymers and surfactants was investigated by means of rheological and surface tension measurements. The polymers used in this study were acrylates/$C_{10-30}$ alkyl acrylate crosspolymer (AC) and ammonium acryloyldimethyltaurate/VP copolymer (AV). And the surfactants were PEG-40 hydrogenated castor oil (HC) and polysorbate 60 (P60). HC and P60 made the micelles intervening between AC polymers, resulting in the increase of viscosity. However, HC showed a similar behavior over the wider range of surfactant concentration than P60. Regarding of surface tensions in the same range of surfactant concentration, AC/HC solution showed the area of increasing surface tension with surfactant concentration in contrast to the AC/P60 solution showing no increasing area. It is assumed that the micelles between AC/HC were formed so cooperatively and strongly that the surfactants located at the surface originally moved to the micelles.

Ultrastructure and Histochemistry on the Integumentary System of the Rockfish, Sebastiscus tertius (Teleostei: Scorpaenidae) (붉은쏨뱅이 (Sebastiscus tertius) 피부계의 미세구조 및 조직화학적 특징)

  • Baek, Jae-Min;Kim, Chul-Won;Lim, Sang-Gu;Lee, Jae-Bong;Lee, Jung-Sick
    • Applied Microscopy
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    • v.34 no.2
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    • pp.83-93
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    • 2004
  • Integumentary structures of the rockfish, Sebastiscus tertius were examined by means of the light and transmission electron microscopy. Stratified epidermal layer consists of supporting cells, unicellular glands, granular cells and mitochondria-rich cells. The epidermal layer could be classified into superficial, intermediate and basal layer by morphology and structure of the supporting cells. Mucous cells of unicellular gland were observed in the superficial and intermediate layer of the epidermis. The mucous materials were identified as acidic and carboxylated mucosubstance by histochemical methods. Club cell has well-developed central vacuole, rough endoplasmic reticula and Golgi complex in the cytoplasm. Granular cells were observed in the superficial layer and contained numerous granules of high electron density. Mitochondria-rich cells are characterized by well-developed microfilaments in cortex and numerous tubular mitochondria in medullar cytoplasm. Three types of pigment cells in the dermal layer could be distinguished with electron density of cytoplasmic inclusions.

Ultrastructural Study on the Cutaneous Granular Glands in Bombina orientalis Boulenger (무당개구리(Bombina orientail Boulenger) 피부 과립선의 미세구조에 관한 연구)

  • 김기영;김관선;문명진;김우갑
    • The Korean Journal of Zoology
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    • v.32 no.2
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    • pp.107-119
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    • 1989
  • The histochemical characteristics of the cutaneous granular glands and its fine structure of the Korean fire bellied toad, Bombino orientalis Boulenger the only species inhabitated in Korea, were studied with light and electron microscopes. By the granular size and histochemical properties, the granular glands were subdivided into two types. The type I glands have small secretory granules (3.6 $\mu$ m), whereas the type II glands contain relatively larger granules (7.5 $\mu$ m). These two types of glands were simple alveolar gland, and they were commonly composed of inner glandular epithelial cells and outermost myoepithelial cells. By the histochemical reactions, these two secretory granules were not responsed to Alcian blue, but weakly positive reaction was observed in type I granular glands by the PAS reaction. And by the scanning electron microscopic observation, extemal morphology of the opening site of the gland duct was resembled to the stomata of the plant leaves. Especially the epithelial cells of the type I glands had fine reticular surface whereas, type II glands had large vesicular surface. These types of the glands conimonly had larger cavities than those of mucous glands, and forming the multinucleated unicellulr structure (syncytium) at the glandular epithelial layers. Secretory granules of these glands were originated from the rough endoplasmic reticulum of the glandular epithelial cells, and by the maturation level of the granule, morphological diversities appeared.

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Realistic and Real-Time Modeling of Numerous Trees Using Growing Environment (성장 환경을 활용한 다수의 나무에 대한 사실적인 실시간 모델링 기법)

  • Kim, Jin-Mo;Cho, Hyung-Je
    • Journal of Korea Multimedia Society
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    • v.15 no.3
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    • pp.398-407
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    • 2012
  • We propose a tree modeling method of expressing realistically and efficiently numerous trees distributed on a broad terrain. This method combines and simplifies the recursive hierarchy of tree branch and branch generation process through self-organizing from buds, allowing users to generate trees that can be used more intuitively and efficiently. With the generation process the leveled structure and the appearance such as branch length, distribution and direction can be controlled interactively by user. In addition, we introduce an environment-adaptive model that allows to grow a number of trees variously by controlling at the same time and we propose an efficient application method of growing environment. For the real-time rendering of the complex tree models distributed on a broad terrain, the rendering process, the LOD(level of detail) for the branch surfaces, and shader instancing are introduced through the GPU(Graphics Processing Unit). Whether the numerous trees are expressed realistically and efficiently on wide terrain by proposed models are confirmed through simulation.