• 한국해양학회지
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• v.21 no.2
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• pp.110-117
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• 1986

In southeastern sea of Korea, ammonium excretion rates of mixed macrozooplankton population ranged from 0.90 to 2.32$\mu\textrm{g}$ atoms NH$\_$4/-Nm$\^$-3/h$\^$-1/ and zooplankton excretion contributed from 3 to 15% of total nitrogen requirement by phytoplankton. Wet weight specific ex cretion rate was averaged to be 3.45$\mu\textrm{g}$ atoms NH$\_$4/-Ng$\^$-1/wet weight h$\^$-1/. Zooplankton biomass in wet weight and protein tended to increase to ward outer outer shelf. GDH assay of macrozooplankton demonstrated a typical Michaelis-Mentenkinetics with 5.1mM of half saturation constant(Km). Protein specific GDH activity in the present study ranged from 1.5 to 3.2$\mu\textrm{g}$ atoms NH $\_$4/-N mg$\^$-1/protein h$\^$-1/. Higher protein specific GDH activity in the outer shelf implies that zooplankters in the outer shelf were more active in nitrogen metabolism grazing higher primary production in the outer shelf. In the present study, averaged GDH/excretion ratio was 18.8${\pm}$2.6(n=6)showing high correlation between zooplankton GDH activity and direct ammonium excretion rate by zooplankton. GDH assay can be extremely useful in the future study for the ammonium regeneration by different size zooplankton fraction in various marine environments.

• Journal of the Korean Recycled Construction Resources Institute
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• v.3 no.4
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• pp.355-365
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• 2015

This study examined the fluidity and strength properties, water resistance, durability, and freeze-thaw of cementless loess mortar using an eco-friendly hardening agent. The experimental result indicates that 28 days compressive and flexural strength of the loess mortar was increased regardless of the weathered granite soil and loess mixture ratio as the replacement ratio of the hardening agent increases. The strengths were significantly increased until 14 days regardless of the hardening agent, while the effect on the strengths increasement was relatively low after 14 days. Thus, the strength development of loess mortar concrete was found to be faster than that of the normal concrete. In addition, when the hardening agent of 10% was used, the average flexural strength was 1.7MPa which is insufficient compared to the 28-day flexural strength of 4.5MPa for the paving concrete. However, the flexural strengths of the loess mortar concrete using the hardening agents of 20% and 30% were 4.0MPa and 5.3MPa, respectively. Thus, the hardening agent need to be at least 20% so that the loess mortar can be used for paving concrete. The experiment for water resistance shows that the repeated absorption and dry reduced mass regardless of the mixing ratio of the loess. The maximum length change also decreased with increasing the substitution rate loess mixture ratio and the hardening agent. The result of the freeze-thaw resistance test indicates that the relative dynamic modulus of elasticity at 300 cycle freeze-thaw with the hardening agents of 20% and 30% were 75% and 79%, relatively. Thus, the hardening agent of at least 20% is required to obtain the relative dynamic modulus of elasticity of 60% for the loess mortar.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.88-88
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• 2021

최근 수자원과 수질관리 분야에 자료기반 머신러닝 모델과 딥러닝 모델의 활용이 급증하고 있다. 그러나 딥러닝 모델은 Blackbox 모델의 특성상 고전적인 질량, 운동량, 에너지 보존법칙을 고려하지 않고, 데이터에 내재된 패턴과 관계를 해석하기 때문에 물리적 법칙을 만족하지 않는 예측결과를 가져올 수 있다. 또한, 딥러닝 모델의 예측 성능은 학습데이터의 양과 변수 선정에 크게 영향을 받는 모델이기 때문에 양질의 데이터가 제공되지 않으면 모델의 bias와 variation이 클 수 있으며 정확도 높은 예측이 어렵다. 최근 이러한 자료기반 모델링 방법의 단점을 보완하기 위해 프로세스 기반 수치모델과 딥러닝 모델을 결합하여 두 모델링 방법의 장점을 활용하는 연구가 활발히 진행되고 있다(Read et al., 2019). Process-Guided Deep Learning (PGDL) 방법은 물리적 법칙을 반영하여 딥러닝 모델을 훈련시킴으로써 순수한 딥러닝 모델의 물리적 법칙 결여성 문제를 해결할 수 있는 대안으로 활용되고 있다. PGDL 모델은 딥러닝 모델에 물리적인 법칙을 해석할 수 있는 추가변수를 도입하며, 딥러닝 모델의 매개변수 최적화 과정에서 Cost 함수에 물리적 법칙을 위반하는 경우 Penalty를 추가하는 알고리즘을 도입하여 물리적 보존법칙을 만족하도록 모델을 훈련시킨다. 본 연구의 목적은 대청호의 수심별 수온을 예측하기 위해 역학적 모델과 딥러닝 모델을 융합한 PGDL 모델을 개발하고 적용성을 평가하는데 있다. 역학적 모델은 2차원 횡방향 평균 수리·수질 모델인 CE-QUAL-W2을 사용하였으며, 대청호를 대상으로 2017년부터 2018년까지 총 2년간 수온과 에너지 수지를 모의하였다. 기상(기온, 이슬점온도, 풍향, 풍속, 운량), 수문(저수위, 유입·유출 유량), 수온자료를 수집하여 CE-QUAL-W2 모델을 구축하고 보정하였으며, 모델은 저수위 변화, 수온의 수심별 시계열 변동 특성을 적절하게 재현하였다. 또한, 동일기간 대청호 수심별 수온 예측을 위한 순환 신경망 모델인 LSTM(Long Short-Term Memory)을 개발하였으며, 종속변수는 수온계 체인을 통해 수집한 수심별 고빈도 수온 자료를 사용하고 독립 변수는 기온, 풍속, 상대습도, 강수량, 단파복사에너지, 장파복사에너지를 사용하였다. LSTM 모델의 매개변수 최적화는 지도학습을 통해 예측값과 실측값의 RMSE가 최소화 되로록 훈련하였다. PGDL 모델은 동일 기간 LSTM 모델과 동일 입력 자료를 사용하여 구축하였으며, 역학적 모델에서 얻은 에너지 수지를 만족하지 않는 경우 Cost Function에 Penalty를 추가하여 물리적 보존법칙을 만족하도록 훈련하고 수심별 수온 예측결과를 비교·분석하였다.

• Progress in Medical Physics
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• v.20 no.4
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• pp.308-316
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• 2009

To achieve the accurate evaluation of given absorbed dose from output dose of linear accelerator photon beam through investigate the characteristics of LiF:Mg,Cu,P TLD powder. This experimental TL phosphor is performed with a commercial LiF:Mg,Cu,P powder (Supplied by PTW) and TL reader (LTM, France). The TLD was exposed to 6 MV X rays of linear accelerator photon beam with range 15 to 800 cGy in blind dose at two hospitals. The dose evaluation of TLD was through the experimental algorithms which were dose dependency, dose rate dependency, fading and powder weight dependency. The glow curve has shown the three peaks which are 110, 183 and 232 degrees of heating temperature and the main dosimetric peak showed highest TL response at 232 high temperature. In this experiments, the LiF:Mg,Cu,P phosphor has shown the 2.5 eV of electron trap energy with a second order. This experiments guided the dose evaluation accuracy is within 1% +2.58% of discrepancy. The TLD powder of LiF:Mg,Cu,P was analyzed to dosimetric characterists of electron captured energy and order by glow shape, and dose-TL response curve guided the accuracy within 1.0+2.58% of output dose discrepancy.

• The Korean Journal of Nuclear Medicine
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• v.26 no.2
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• pp.327-332
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• 1992

$^{99m}Tc-dimercaptosuccinic$ acid (DMSA) 주사후 일정시간에 측정한 절대적 신섭취량은 기능이 살아있는 신피질량과 관계있다. 소아의 신기능은 출생후 계속 성숙되어 생후 약 $1\sim2$년에 성인의 기능에 도달하는데 DMSA섭취도 성인과는 다른 양상을 보일 것으로 기대되며 신질환에서 절대적 신섭취율의 평가는 연령을 고려해야 할 것이다. 저자들은 DMSA 스캔을 시행한 소아 환자를 대상으로 스캔상 피질 결손이 없으며 양측신의 섭취율이 비슷하고 혈중 크레아티닌치가 정상인 경우를 대조군으로 하여 연령별 DMSA의 절대적 신섭취율을 구하였고 방광요관역류를 가진 환아를 대상으로 DMSA스캔을 시행하고 신섭취율을 조사하였다. 1) 대조군은 모두 65명으로 좌우측 신섭취율의 유의한 차이는 없었으며 연령에 따라 2세경에 플라토에 도달하였는데 한쪽 신장의 평균섭취율은 3개월 미만이 $14.5{\pm}3.1%$ ID, 3개월에서 6개월 미만이 $17.2{\pm}2.1%$ID, 6개월에서 1년 미만이 $18.4{\pm}1.3%$ID, 1년에서 1년6개월 미만이 $19.3{\pm}1.1%$ID, 1년 6개월에서 2년 미만이 $21.9{\pm}2.0%$ID, 2세이상 15세이하가 $20.1{\pm}0.6%$ID였으며 전체 평균섭취율은 $19.4{\pm}0.5%$ID (injected dose, $mean{\pm}S.E.$)였다. 2) 방광요관역류를 가진 환아는 55명 (일측성 56명, 양측성 29명)으로 109신장을 대상으로 하였다. 방광요관역류의 정도와 피질결손의 수와는 대체로 비례관계가 있었으나 방광요관역류가 없으면서 피질결손이 있는 경우가 25신장중 2예 (8%)였으며, 방광요관역류가 있는 84신장중 27예 (32.1%), 이중에서 방광요관역류가 3도 이상인 62신장중 13예 (21%)에서는 피질결손이 없었다. 3) 이환신의 DMSA 섭취율을 연령에 따른 대조군의 섭취율에 대한 비(섭취율비)로 나타내면 한쪽에 역류가 있을 때 이환신의 경우 $0.55{\pm}0.06$, 정상신의 경우 $1.34{\pm}0.05$이었으며, 양쪽에 역류가 있을 때는 평균 $0.82{\pm}0.08$ $(mean{\pm}S.E.)$ 이었다. 4) 피질결손이 있는 신장의 절대 DMSA 신섭취율은 감소되어 있었고 상대측 신장의 섭취율은 피질 결손이 있더라도 대상적인 증가의 경향을 보였다. 이상의 결과로 소아에서 DMSA 절대적 신섭취율의 연령에 따른 변화를 알 수 있었으며 방광요관역류의 정도와 피질결손의 정도가 반드시 비례하지만은 않아서 시간경과에 따른 추후 검사가 필요하리라 생각된다. 또한 방광요관역류가 있는 환아에서 DMSA 섭취율로 신기능을 평가할 때, 특히 영유아에서 연령에 따른 고려가 있어야 할 것으로 보인다.

• Radiation Oncology Journal
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• v.28 no.3
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• pp.177-183
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• 2010

Purpose: Simulation using computed tomography (CT) is now widely available for radiation treatment planning for breast cancer. It is an important tool to help define the tumor target and normal tissue based on anatomical features of an individual patient. In Korea, most patients have small sized breasts and the purpose of this study was to review the margin of treatment field between conventional two-dimensional (2D) planning and CT based three-dimensional (3D) planning in patients with small breasts. Materials and Methods: Twenty-five consecutive patients with early breast cancer undergoing breast conservation therapy were selected. All patients underwent 3D CT based planning with a conventional breast tangential field design. In 2D planning, the treatment field margins were determined by palpation of the breast parenchyma (In general, the superior: base of the clavicle, medial: midline, lateral: mid - axillary line, and inferior margin: 2 m below the inframammary fold). In 3D planning, the clinical target volume (CTV) ought to comprise all glandular breast tissue, and the PTV was obtained by adding a 3D margin of 1 cm around the CTV except in the skin direction. The difference in the treatment field margin and equivalent field size between 2D and 3D planning were evaluated. The association between radiation field margins and factors such as body mass index, menopause status, and bra size was determined. Lung volume and heart volume were examined on the basis of the prescribed breast radiation dose and 3D dose distribution. Results: The margins of the treatment field were smaller in the 3D planning except for two patients. The superior margin was especially variable (average, 2.5 cm; range, -2.5 to 4.5 cm; SD, 1.85). The margin of these targets did not vary equally across BMI class, menopause status, or bra size. The average irradiated lung volume was significantly lower for 3D planning. The average irradiated heart volume did not decrease significantly. Conclusion: The use of 3D CT based planning reduced the radiation field in early breast cancer patients with small breasts in relation to conventional planning. Though a coherent definition of the breast is needed, CT-based planning generated the better plan in terms of reducing the irradiation volume of normal tissue. Moreover it was possible that 3D CT based planning showed better CTV coverage including postoperative change.

• Journal of Astronomy and Space Sciences
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• v.25 no.2
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• pp.101-112
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• 2008

Systematic CCD observations of times of minimum lights for eclipsing binaries has been carried out from 2002 to 2007 at Campus Station of Chungbuk National University Observatory which is located in Cheongju city, Korea. As a by-product of our observations, photometric data for stars in CCD images taken from 2005 to 2007 were used to determine 1st order atmospheric extinction coefficient (hereafter AEC) and seasonal and yearly variations of the AECs were studied. Total nights used for determination of AECs were 57 days in 2005, 51 days in 2006, and 63 days in 2007. As a result the annual mean value of the AECs per air mass is calculated as $0.^m34{\pm}0.^m18$ for 2005, $0.^m38{\pm}0.^m19$ for 2006, and $0.^m45{\pm}0.^m20$ for 2007. These values show that the AECs and their standard deviations are two and four times, respectively, larger than those of normal observatories which are not located near large cities. Annual comparison between concentration of atmospheric fine dust and coefficient of atmospheric extinction show strong correlation between two quantities of which time variations show similar patterns. The AECs for the east sky show larger than those for the west sky. It can be easily understood by the reasonable possibility that air pollutants remain more in the east sky than in the west because the east area of Cheongju city has been more developed than the west one. In conclusion the atmospheric extinction of the night sky of Cheongju city has an annual trend of increase of $0.^m06\;airrnass^{-1}\; year^{-1}$ implying that it may take only about 13 years for Cheongju city to have 2 times brighter night sky than the present one. Our study highlights that variations of AEC can be used as an important indicator of air pollution to monitor night skies.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.34 no.6
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• pp.643-651
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• 2001

Paddlewheel-driven circulation in a culture pond has been simulated based on the depth integrated 2 dimensional hydrodynamic model. Acceleration by paddlewheel is expressed as shaft force divided by water mass discharged by paddlewheel blades. The model has been calibrated and applied to culture ponds as following steps:- i) The model predicted velocities at every 10 m along longitudinal direction from the paddlewheel. The model was calibrated comparing the results with the measured values at mass correction factor $\alpha$ and dimensionless eddy viscosity constant $\gamma$, respectively, in a range $15\~20$ and 6. ii) Wind shear stress was simulated under conditions of direction $0^{\circ}C,\;90^{\circ}C\;and\;180^{\circ}C$ and speed 0.0, 2.5, 5.0 and 7.5 m/s. Change rate of current speed was <$1\%$ at wind in parallel or opposite direction to the paddlewheel-driven jet flow, while $4\%$ at orthogonal angle. iii) The model was then applied to 2 culture ponds located at the Western coast of Korea. The measured and predicted currents for the ponds were compared using the regression analysis. Analysis of flow direction and speed showed correlation coefficients 0.8928 and 0.6782 in pond A, 0.8539 and 0.7071 in pond B, respectively. Hence, the model is concluded to accurately predict circulation driven by paddlewheel such that it can be a useful tool to provide pond management strategy relating to paddlewheel operation and water quality.

• Journal of Korean Society of Forest Science
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• v.12 no.1
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• pp.1-11
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• 1971

The present study was carried out in order to investigate seasonal variation in tannin, sugar and protein contents of persimmon fruits, Five varieties of Diospyros kaki Thunberg, i. e, Buyoo, Wolha, Kapjubackmok, Pyungmuhek, Heuksi, and Goyom (Diospyros Lotus Linne var. typica Makino) growing in Jeonbug area were used as the experimental material. The result are summarized as follow; 1. Maximum tannin contents were 4% in Buyoo, 5.46% in Wolha, 5.4l% in Kapjubackmok, 5.1 % in Pyungmuhek, 9.2% in Heuksi, and 26.1% in Goyom, respectively. Therefore, Heuksi and Goyom were considered to be the most useful as tannin material. 2. The most suitable season for tannin extraction was thought to be July with most varieties but it was August with Goyom. 3. The total sugar contents seemed to increse linearly. Linear regressions are as follows. Buyoo ; $\hat{Y}=0.2394x+3.861$ Wolha ; $\hat{Y}=0.3093x-1.148$ Kapjubackmok ; $\hat{Y}=0.3173x-1.3708$ Pyungmuhek ; $\hat{Y}=0.2796x+0.982$ Heuksi ; $\hat{Y}=0.3233x-3.242$ Goyom ; $\hat{Y}=0.1555x-4.780$ 4. Average crude protein contents of fruits through the year were 5.32% in Buyoo, 4.97% in Kapjubackmok, 4.49% in Goyom, 4.11% in Wolha, 4.02% in Heuksi, and 3.6% in Pyungmuhek, respectively. 5. The crude protein contents tend to decrease gradually after fruit setting.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.1
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• pp.9-15
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• 2007

Purpose: Repetitive transcranial magnetic stimulation (rTMS) has recently been clinically applied in the treatment of drug resistant depressed patients. There are mixed findings about the efficacy of rTMS on depression. Furthermore, the influence of rTMS on the physiology of the brain is not clear. We prospectively evaluated changes of regional cerebral blood flow (rCBF) between pre- and post-rTMS treatment in patients with drug resistant depression. Materials and Methods: Twelve patients with drug-resistant depression (7 male, 5 female; age range: $19{\sim}52$ years; mean age: $29.3{\pm}9.3$ years) were given rTMS on right prefrontal lobe with low frequency (1 Hz) and on left prefrontal lobe with high frequency (20 Hz), with 20-minute-duration each day for 3 weeks. Tc-99m ECD brain perfusion SPECT was obtained before and after rTMS treatment. The changes of cerebral perfusion were analyzed using statistical parametric mapping (SPM; t=3.14, uncorrected p<0.01, voxel=100). Results: Following areas showed significant increase in rCBF after 3 weeks rTMS treatment: the cingulate gyrus, fusiform gyrus of right temporal lobe, precuneus, and left lateral globus pallidus. Significant decrement was noted in: the precental and middle frontal gyrus of right frontal lobe, and fusiform gyrus of left occipital lobe. Conclusion: Low-frequency rTMS on the right prefrontal cortex and high-frequency rTMS on the left prefrontal cortex for 3 weeks as an add-on regimen have increased and decreased rCBF in the specific brain regions in drug-resistant depressed patients. Further analyses correlating clinical characteristics and treatment paradigm with functional imaging data may be helpful in clarifying the pathophysiology of drug-resistant depressed patients.