• The Journal of the Acoustical Society of Korea
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• v.36 no.3
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• pp.172-178
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• 2017

Ultrasound has been widely used for biological and medical applications including induction of cell death, but a precise mechanism of induced cell death by ultrasound is controversial. In this study, an irradiation system with 40 kHz ultrasound was developed for a suitable cell death test of a representative unicellular organism, yeast, and used to study the biological effect of ultrasound on inducing cell death. Potassium Iodide (KI) dosimetry was used to devise an optimal system that successfully delivers 40 kHz ultrasound and produces reactive oxygen species in a 1.5 ml Eppendorf tube. Cell death was observed in an ultrasound transmission time-dependent fashion in this system. Thermal effect during irradiation was not observable in ultrasound induced cell death. Co-treatment of 40 kHz ultrasound and hydrogen peroxide showed a synergistic effect in inducing cell death. This finding suggests that 40 kHz ultrasound is related to reactive oxygen species formation. However, NAC (N-acetyl-L-cysteine) oxygen scavenger slightly inhibited the cell death by 40 kHz ultrasound. It was also found that 40 kHz ultrasound induced cell death was slightly inhibited by inhibitors of necrosis or apoptosis (glycyrrhizin or zVAD-fmk). This study suggests that cell death induced by 40 kHz ultrasound may not be exclusively related to reactive oxygen species formation and thermal effects in irradiated yeast cells.

• The Journal of the Korea Contents Association
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• v.13 no.5
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• pp.303-310
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• 2013

Thyroid nodular disease is the most frequently appeared in thyroid disease. Thyroid ultrasonography offers location of nodules, size, the number, information of internal echo characteristic. Thus, it makes possible to sort high-risk nodule containing high possibility about thyroid cancer and to induct precisely when take a Fine Needle Biopsy Aspiration. On thyroid nodule, the case which is diagnosed as malignant is less than 5% but screening test is very important on ultrasound and also must be reduced unnecessary procedure. Therefore, in this study an approach for describing a region is to quantity its texture content. We applied TFA algorithm on case which has been pathologically diagnosed as papillary thyroid cancer. we obtained experiment image which set the ROI on ultrasound and cut the $50{\times}50$ pixel size, histogram equalization. Consequently, Disease recognition detection efficiency of GLavg, SKEW, UN, ENT parameter were high as 91~100%. It is suggestion about possibility on CAD which distinguishes thyroid nodule. In addition, it will be helpful to differential diagnosis of thyroid nodule. If the study on additional parameter algorithm is continuously progressed from now on, it is able to arrange practical base on CAD and it is possible to apply various disease in the thyroid US.

• Journal of the Korean Society for Nondestructive Testing
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• v.17 no.2
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• pp.108-113
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• 1997

Ultrasonic testing is one of the most widely used method of nondestructive testing for pre-service inspection(PSI) & in-service inspection(ISI) in structures of bridges, power plants, chemical plants & heavy industrial fields. It is very important to estimate safety, life, quality of structures. Also, a lot of research for quantities evaluation & analyses inspection data is proceeding. But traditional portable ultrasonic flaw detector had been following disadvantages. 1) Analog ultrasonic flaw detector decreased credibility of ultrasonic test, because it is impossible for saving data & digital signal processing. 2) Stand-alone digital ultrasonic flaw detector cannot effectively evaluate received signals because of lack of its storage memory. To overcome this shortcoming, we develop the computer based ultrasonic flaw detector for nondestructive testing. It can store the received signal and effectively evaluate the signal, and then enhance the reliability of the testing results.

• Journal of the Korean Society for Nondestructive Testing
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• v.20 no.1
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• pp.27-32
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• 2000

In this paper, ultrasonic wave in the thermoelastic regime was generated in a steel disk by illuminating a pulse laser (Q-switched Nd:YAG) on the surface of the sample and was detected on the other side by Michelson interferometer which was stabilized by feed back control. The experimentally detected displacement waveform of the ultrasonic wave showed good agreement with the theoretically expected one. Also it was shown that sound speeds of longitudinal and shear wave were similar to ones measured by pulse-echo method using a contact transducer. As an application of the noncontact ultrasonic measurement by using laser based ultrasonics, the sound speed in the sample was monitored while the sample was heated in a furnace, and the result showed that it decreased according to the increase of sample temperature.

• Journal of the Korean Society for Nondestructive Testing
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• v.21 no.2
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• pp.152-162
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• 2001

Laser-generated ultrasonic technique which is one of the reliable nondestructive evaluation techniques has been applied to evaluate the integrity of structures by analyzing the characteristics of signal obtained from surface crack. Therefore, the signal analysis of the laser-generated ultrasonics is absolutely necessary for the accurate and quantitative estimation of the surface defects. In this study, one-sided measurement by laser-generated ultrasonic has been applied to evaluate the depth of the surface-breaking crack in the materials. However, since the ultrasonic waveform excited by pulse laser is very difficult to distinguish the defect signals, it is necessary to consider the signal analyses of the transient waveform. Wavelet Transform(WT) is a powerful tool for processing transient signals with temporally varying spectra that helps to resolve high and low frequency transient components effectively. In this paper, the analyses of the surface-breaking crack of the ultrasonic signal excited by pulse laser are presented by employing the WT analyses.

• Journal of KIISE:Software and Applications
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• v.33 no.4
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• pp.418-426
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• 2006

This paper proposes a robust and efficient segmentation method for a cardiac ultrasound image taken from a probe inserted into the heart in surgery. The method consists of three steps: initial boundary extraction, whole boundary modification using confidence competition, and local boundary modification using the rolling spoke method. Firstly, the initial boundary is extracted with threshold regions along the global spokes emitted from the center of an ultrasound probe. Secondly, high confidence boundary edges are detected along the global spokes by competing among initial boundary candidate and new candidates achieved by edge and appearance information. finally, the boundary is modified by rolling local spokes along concave regions that are difficult to extract using the global spokes. The proposed method produces promising segmentation results for the ultrasound cardiac images acquired during surgery.

• Journal of the Korean Society for Nondestructive Testing
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• v.32 no.1
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• pp.41-46
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• 2012

As the development of MEMS/NEMS structure and application technology the demand for an assessment of the mechanical properties have increased. The mechanical properties are mainly evaluated by using tensile test or ultrasonic wave measurement. However, the new technology have been developed such as nano-indentation, guided wave method because they have a limitation in case of a thin plate and thin film. In the study, the guided wave velocities are measured by electromagnetic-acoustic transducer(EMAT), the material properties of thin metallic foils are obtained using optimization process of the theoretical and experimental group velocity of guided wave. The Young's modulus obtained by the optimization process(201.6 GPa), nano-indentation(207.0 GPa) and literature value(203.7 GPa) of a $50{\mu}m$ thick nickel thin plate shows good agreement within 3%.

• Journal of the Korean Society for Nondestructive Testing
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• v.20 no.5
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• pp.373-380
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• 2000

It is useful to use NDE methods to assess the mechanical properties of materials since destructive methods are time-consuming and usually require cutting of sample from the material/component. In the present research, ultrasonic characteristics have been utilized to evaluate changes of mechanical properties due to heat treatment temperature and condition. The attenuation coefficient of ultrasonic wave increased as the heat treatment temperature because the grain size increased in size as the temperature. The attenuation coefficient decreased as the heat treatment has been progressed (quenched, tempered, PWHT). In the case of ultrasonic velocity measurement, velocity difference between quenched and tempered/PWHT was 40 m/s. There was a good relationship between the attenuation coefficient and the toughness. The relationship can be used for the nondestructive evaluation of the forged reactor vessels. Moreover, the method may be effectively used in the field application.

• The Journal of the Acoustical Society of Korea
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• v.40 no.2
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• pp.169-175
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• 2021

Recently, an ultrasound hologram and its applications have gained attention in the ultrasound research field. However, the determination technique of transmit signal phases, which generate a hologram, has not been significantly advanced from the previous algorithms which are time-consuming iterative methods. Thus, we applied the deep learning technique, which has been previously adopted to generate an optical hologram, to generate an ultrasound hologram. We further examined the Deep learning-based Holographic Ultrasound Generation algorithm (Deep-HUG). We implement the U-Net-based algorithm and examine its generalizability by training on a dataset, which consists of randomly distributed disks, and testing on the alphabets (A-Z). Furthermore, we compare the Deep-HUG with the previous algorithm in terms of computation time, accuracy, and uniformity. It was found that the accuracy and uniformity of the Deep-HUG are somewhat lower than those of the previous algorithm whereas the computation time is 190 times faster than that of the previous algorithm, demonstrating that Deep-HUG has potential as a useful technique to rapidly generate an ultrasound hologram for various applications.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2007.04a
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• pp.274-274
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• 2007

1)모바일 로봇의 위치인식기술; 모바일 로봇의 위치인식 방법, 특징, 개발동향 소개 2)In Door GPS;모바일 로봇의 위치인식기술의 하나인 Active beacon system에 대해 소개하고 이를 구현하기 위한 방법, 특징, 개발 동향 소개 (주)나인티시스템에서 개발한 초음파 및 RF를 이용한 위치인식기술인 iGS를 소개함 3)iGS의 구현 방법;iGS에 적용된 알고리즘 및 이의 구현 결과 소개 4)적용사례 및 응용분야; iGS의 작용 사례 및 응용 분야 소개 5)문제점 및 개선 방향; iGS의 문제점 및 개선 방향 소개