• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2003.10a
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• pp.849-852
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• 2003

인터넷을 이용한 정보가 모든 정보 전달의 기본이 되고 있다. 따라서 이러한 정보 전달의 보호를 위한 정보보호 산업이 급성장하게 되었다. 다라서, 본 논문에서는 향우, 2007년 경에 IPV6를 기반으로 하는 유비쿼터스 환경 하에서의 각 가정의 홈 네트워크를 구성할 때 필요한 보안적인 측면의 방법에 대해서 제시하고자 한다. 이러한 다양화된 디지털 매체가 디지털 가전, 정보통신 시스템과 접속 하여 새로운 메카니즘의 보안 설계 대상이 필요하게 됨에 따라서, 새로운 정보보호의 접근이 필수적 이다. 본 논문에서 제시하고자 하는 내용은 암호학적으로 안전한 홈네트워크의 구성과 이를 실현하기 위해서 요구되어지는 다양한 고려사항 등을 분석하여 차세대의 멀티 컴퓨팅 환경 하에서의 정보보호 시스템 구축에 이해를 돕고자 한다.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2013.10a
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• pp.792-796
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• 2013

A practical process to optimize engine mounts on construction equipment is presented in this research. Transmitted force from the engine is estimated by using stiffness of the mount rubber which varies with frequency, amplitude and pre-load, and by the engine excitation force that comes from piston mass and gas pressure and so on. The transmitted force is measured through TPA(Transfer Path Analysis) and is then compared with the estimated force. The optimum mount position and stiffness are solved using MATLAB. The result shows the improvement on engine mount vibration.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.7B
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• pp.745-759
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• 2011

In this paper, we propose the global handover mechanism that is able to provide the unlimited range of next-generation multimedia mobile services in an integrated environment. This mechanism consists of a multicast source based forwarding scheme and a global session management scheme. Global session management scheme provides LMA session information management, global mobility and route optimization. Multicast source based forwarding scheme delivers data between previously attached LMA and newly attached LMA without packet loss. In addition, this scheme removes the redundancy of buffered data. We present a performance evaluation and features analysis by the simulations using the ns-2. Global session management scheme has a less handover latency, propagation delay and signaling cost than the conventional methods. Multicast source based forwarding scheme can deliver buffer data without loss and it has less buffer size than conventional method.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.42 no.1
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• pp.64-76
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• 2017

Routing in mobile ad hoc networks (MANETs) is highly challenging because of the dynamic nature of network topology. AntHocNet is a bio-inspired routing protocol for MANETs that mimics the foraging behavior of ants. However, unlike many other MANET routing protocols, the paths constructed in AntHocNet are unidirectional, which requires a separate path setup if a route in the reverse direction is also required. Because most communication sessions are bidirectional, this unidirectional path setup approach is often inefficient. Moreover, AntHocNet suffers from looping problems because of its property of multiple paths and stochastic data routing. In this paper, we propose a modified path setup procedure that constructs bidirectional paths. We also propose solutions to some of the looping problems in AntHocNet. Simulation results show that performance is significantly enhanced in terms of overhead, end-to-end delay, and delivery ratio when loops are prevented. Performance is further improved, in terms of overhead, when bidirectional paths setup is employed.

• Polymer(Korea)
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• v.30 no.4
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• pp.279-285
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• 2006

Non-viral gene carriers continue to attract a great deal of interest due to advantageous safety profile. Among the non-viral gene carriers, cationic liposomes or synthetic gene carriers are efficient DNA carriers in vitro. but their in vivo applications are greatly hampered because of low biocompatibility. On the other hand, chitosan, a natural cationic polysaccharide, is a candidate non-viral vector for gene delivery because of its low cytotoxicity and high positive charges. In this work, targeted gene carrier was synthesized to target artery wall cells using low molecular water-soluble chitosan (LMWSC). The molecular weight $(M_W)$ and degree of de acetylation (DDA) of LMWSC were measured by relative viscometer and Kina titration. respectively. The structure of LMWSC was analyzed by measuring FTIR, $^1H-NMR,\;and\;^{13}C-NMR$. AWBP-PEG-g-LMWSC was synthesized by conjugation of the artery wall binding peptide (AWBP), a specific targeting peptide, to the end of pegylated LMWSC as a gene carrier to target artery wall cells. The synthesized AWBP-PEG-g-LMWSC were analyzed by measuring FTIR, $^1H-NMR$, zeta -potentiometer, and atomic force microscopy (AFM).

• Korean Journal of Clinical Laboratory Science
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• v.52 no.1
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• pp.62-68
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• 2020

Cisplatin (CDDP) is a chemotherapy agent used for patients with ovarian cancers. CDDP activates multiple signaling pathways, which causes various cellular reactions according to the type of cancer cells. Therefore, it is difficult to clearly conclude its signaling pathways. The purpose of this study is to determine the role of the signal protein of Akt/ERK1/2 and MAPK by CDDP-induced apoptosis in ovarian cancer cells (SKOV3). As a result, the number of apoptosis increased according to the TUNEL assay, and flow cytometric analysis confirmed that the percentage of sub-G1 early apoptosis was 8.73% higher than the control. The PARP and caspase-3 activity that appeared in the process of apoptosis was increased and the Bcl-2 expression was decreased. It was verified that the Akt and ERK1/2 activity was decreased, and p38 and JNK activity increased in a time dependent fashion. In conclusion, these results demonstrate that cisplatin inhibits the proliferation of ovarian cancer cells by inhibiting Akt activity and induces apoptosis by modulating the MAPK signaling pathway. However, a decrease in the ERK1/2 activity by CDDP was the opposite result to the result shown from the HeLa cells. For this reason, further research on signaling pathways is necessary. These results are expected to be useful for ovarian cancer treatment strategies targeting the MAPK pathway.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2010.05a
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• pp.327-327
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• 2010

자동차에서 실내음질은 구매결정 요소들 중의 하나로 그 중요성이 점차 증가하고 있다. 따라서 다양한 운전조건에서 운전자가 기대하는 실내음질의 기대 수준을 충족시켜야 한다. 소비자는 운전경험과 습관에 따라 기대하는 음질에 차이가 있고 소리에 대한 표현방식도 모호하기 때문에 이러한 주관적 특성을 하나의 통일된 표현으로 정의 하기가 어렵다. 그러나 지난 이십여 년 동안의 음질개발과 차량 실내소음 주관평가의 통계처리로 통일된 표현을 할 수 있었다. 나아가 심리음향학 및 신호처리기술의 발달과 꾸준한 음질연구결과로 소리특성을 객관적으로 나타내는 소리의 시각화가 가능하였으며, 운전자가 인식하는 주관평가와의 상관관계를 높여 차량의 대표적인 음질인자로 정량화하여 음질목표를 설정할 수 있었다. 실내소음의 구성은 엔진 투과음, 흡배기 소음, 바람 소음, 도로 기인 소음 등으로 다양하므로 소음원에 따라 음의 균형을 맞추어 조화로운 음질개발을 하는 것이 중요했다. 또한 차량 판매되는 지역에 따라 선호음이 상이하여 지역별 실내음질의 차별화가 필요했다. 궁극적으로는 운전자의 감성품질을 만족할 수 있도록 음을 제어하여 브랜드 사운드를 개발하고 있다. 이러한 실내음질을 달성하기 위한 방법으로 소음원과 전달경로에 대해 기여도를 분석하고, 경로를 구성하는 시스템 별로 세분화하여 시스템 목표를 설정하였다. 시스템 개발에 중요한 인자로 차량의 동강성 및 흡차음 성능을 들 수 있다. 특히 디젤차량의 비중이 큰 유럽업체의 차량의 동강성 및 흡차음 개발 능력은 높게 평가되고 있다. 이에 유럽의 부품전문회사가 가지고 있는 해석과 시험적인 개발 방법을 통하여 전달계 특성을 만족하기 위한 시스템의 동강성 및 흡차음 특성을 개발하고 있다. 차량음질 튜닝의 중요한 기법 중 하나로 흡배기 개발을 추진하고 있다. 친환경자동차인 하이브리드차량, 전기차량 및 연료전지차량의 경우 전기구동부품에서 발생하는 각종 이음 발생을 최소화 했다. 보행자를 보호하고 운전의 즐거움을 향상하기 위한 가상사운드 개발을 진행하고 있다. 회사 수익성 향상을 위한 원가절감 및 구조 경량화에 따른 음질악화와 연비 향상 및 배기가스 규제 강화로 고성능 고출력 엔진탑재에 따른 음질악화 요인을 극복해야 했다. 운전자의 청감은 차량의 운전성에 따라서도 크게 영향을 받게 되므로 엔진제어와 변속기제어를 통해 음질과 운전성이 조화를 이룰 수 있도록 개발하고 있다. 향후, 소음원에 따른 시스템 최적화 개발, 운전성과 음질 연계 개발과 친환경차량의 가상사운드 개발 등이 자동차 음질 개발의 중요한 이슈로 생각한다.

• The Journal of the Acoustical Society of Korea
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• v.32 no.6
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• pp.455-471
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• 2013

Active sonar has been commonly used to detect targets existing in the shallow water. When a signal is transmitted and returned back from a target, it has been distorted by various properties of acoustic channel such as multipath arrivals, scattering from rough sea surface and ocean bottom, and refraction by sound speed structure, which makes target detection difficult. It is therefore necessary to consider these channel properties in the target signal simulation in operational performance system of active sonar. In this paper, a monostatic active sonar system is considered, and the target echo, reverberation, and ambient noise are individually simulated as a function of time, and finally summed to simulate a total received signal. A 3-dimensional highlight model, which can reflect the target features including the shape, position, and azimuthal and elevation angles, has been applied to each multipath pair between source and target to simulate the target echo signal. The results are finally compared to those obtained by the algorithm in which only direct path is considered in target signal simulation.

• Journal of Advanced Marine Engineering and Technology
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• v.40 no.9
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• pp.799-804
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• 2016

Broadband powerline communication (BPLC) uses distribution lines as a medium for achieving effective bidirectional data communication along with electric current flow. As the material characteristics of power lines are not good at the communication channel, the development of power line communication (PLC) systems for internet, voice, and data services requires measurement-based models of the transfer characteristics of the network suitable for performance analysis by simulation. In this paper, an analytic model describing a complex transfer function is presented to obtain the attenuation and path parameters for a multipath power line model. The calculated results demonstrated frequency-selective fading in multipath channels and signal attenuation with frequency, and were in good agreement with the experimental results. Inductive coupling units are used as couplers for coupling the signal to the power line to avoid physical connections to the distribution line. The inductance of the ferrite core, which depends on the frequency, determines the cut-off frequency of the inductive coupler. Coupling loss can be minimized by increasing the number of windings around the coupler. Coupling efficiency was improved by more than 6 dB with three windings compared to the results obtained with one winding.

• Korean Journal of Food Science and Technology
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• v.50 no.5
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• pp.555-563
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• 2018

Barley has nutritional benefits due to its high dietary fiber content; therefore, the intake of whole barley grains is recommended. However, barley is often consumed in the fermented form because of the improved texture and digestibility. The present study was designed to elucidate the intracellular signaling pathway for macrophage activation by the polysaccharide BF-CP from fermented barley. BF-CP is a neutral polysaccharide, composed of neutral sugars, including glucose (70.7%), xylose (11.4%), and arabinose (9.0%). BF-CP exhibited macrophage-stimulatory activity by inducing the production of interleukin (IL)-6, tumor necrosis factor $(TNF)-{\alpha}$, and nitric oxide in RAW 264.7 macrophages. Further, BF-CP treatment strongly increased the IL-6 and $TNF-{\alpha}$ gene expression in a concentration-dependent manner. Signal transduction experiments using immunoblotting showed that BF-CP phosphorylated mitogen-activated protein kinases (MAPKs), such as c-Jun N-terminal kinase, extracellular signal-regulated kinase, and p38, and nuclear factor $(NF)-{\kappa}B$, in RAW 264.7 cells in a concentration-dependent manner. These results suggest that BF-CP activates the macrophages via MAPK and $NF-{\kappa}B$ pathways, and also induces an increase in the production of cytokines.