• Journal of Life Science
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• v.29 no.9
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• pp.941-948
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• 2019

Colorectal cancer is a major health problem in industrialized countries. Ziyuglycoside II ($3{\beta}-3-{\alpha}$-1- arabinopyranosyloxy-19-hydroxyurs-12-en-28-oicacid), a triterpenoid saponin isolated from the roots of Sanguisorba officinalis L., possesses antioxidant, antiangiogenic, and anticancer properties. However, the therapeutic function of ziyuglycoside II in colitis-associated colorectal carcinogenesis is undefined. In the present study, the effect of ziyuglycoside II on colitis-associated colon cancer induced in mice using azoxymethane (AOM)/dextran sulfate sodium (DSS) was explored. The AOM model recapitulates many features of human colon cancer, but it lacks an inflammatory component. DSS induces colitis and promotes AOM-induced colon cancer in mice. BALB/c mice were injected with AOM and administered 2% DSS in drinking water. The mice were given ziyuglycoside II (1 or 5 mg/kg) orally three times per week, and colonic tissue was collected at 64 days. Administration of ziyuglycoside II markedly diminished the formation of colonic tumors. Western blot and immunohistological analyses showed that ziyuglycoside II noticeably decreased nuclear factor kappa-B-positive cells and levels of inflammation-related proteins, such as inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-${\alpha}$, and interleukin-6 in colon tissue. It also prompted apoptosis. Ziyuglycoside II treatment augmented cleaved forms of caspase-3, caspase-7, and poly (ADP-ribose) polymerase in colonic tissues. In conclusion, ziyuglycoside II could defend against colitis-associated tumorigenesis in mice by inhibiting inflammation and inducing apoptosis. This shows a promising chemopreventive potential for its use in colitis-associated colon cancer.

• The Korean Journal of Archival Studies
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• no.34
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• pp.29-56
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• 2012

Since 2011, 148 public institutions (including the central administrative agencies) have been moving to the provinces. First of all, the Prime Minister's Office began to be relocated to Sejong City on 14 Sep, 2012, followed by 6 central administrative agencies and their cooperative agencies are planned to move there. With regard to public institutions' relocation, the issue of record centers' relocation should be also considered. In respect that there is lack of facilities, manpower, and equipment in most record centers, it is doubtable whether the relocation of record centers will end successfully. The purpose of this study is to investigate the current state of record centers and to grasp their issues when they are relocated. The targets are the central administrative agencies which will move in 2012. The data was collected by request of information disclosure and personal contact with record centers. After analyzing collected data, both the issues caused by relocation and the cases of environment improvement were assured. In addition, the improvement of record centers' limitation (ex. The lack of exclusively responsible workers, the shortage of facilities, space and budget etc.) was suggested.

• Korean Journal of Remote Sensing
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• v.35 no.2
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• pp.343-346
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• 2019

This letter describes a development of satellite-based forest withering index for detection of fire burn area and its application to the Goseong-Sokcho and Gangneung-Donghae wildfires in April 4, 2019. Withered forest has very different spectral characteristics from healthy forest. In particular, a false color composite of R-NIR-G represents such difference very clearly. Using Sentinel-2 images with the forest withering index, we derived the area burned by the wildfires: approximately 701.16 ha for Goseong-Sokcho and approximately 710.60 ha for Gangneung-Donghae, although official record will be announced by the Korean government later.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.825-835
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• 2018

This study is a descriptive research to examine the relationship between critical thinking disposition, clinical performance ability, and self-concept of nursing profession according to degree of self-leadership among nursing college students. The data were collected from 165 nursing students in 3rd & 4th grade using self-report questionnaire and analyzed by t-test, ANOVA, Pearson's correlation coefficient, and Multiple Regression. Self-leadership according to general characteristics showed significant differences according to grade, academic achievement, motivation, and major satisfaction. Self-leadership was found to have a positive correlation with critical thinking disposition, clinical performance ability, and self-concept of nursing professional. Analysis of the effects of general characteristics affecting sief-leadership, critical thinking disposition, nursing proFessional selF-concept and clinical performance on selF-leadership showed that they were explained by 49.9%, critical thinking disposition was the most important factor. This suggests that nursing students' self-leadership can be improved effectively by promoting critical thinking disposition. Also in reality, there are many difficulties such as the problems in the system of the majors, but it is necessary to operate a continuous education program to strengthen the self-leadership for the nursing college students by seeking various methods.

• Journal of the Health Care and Life Science
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• v.8 no.2
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• pp.165-172
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• 2020

This study was conducted to identify the subjective happiness and self-esteem of nursing students and how these variables affect clinical practice stress. Participants consisted of 199 nursing students who were in the third and fourth years who had experienced clinical practice at two nursing universities located in Gyeongnam, and agreed to the survey. Data were collected using questionnaires from June 15 to August 29, 2020. Collected data were analyzed using the SPSS 22.0 statistics program with descriptive statistics, an independent t-test, ANOVA, Scheffe's test, and multiple regression. The mean score for subjective happiness was 4.87 (out of 7), the mean for self-esteem was 3.84 (out of 5), and clinical practice stress was 2.77 (out of 5). The significant predictors of the clinical practice stress were gender, major satisfaction and self-esteem, and the explanatory power of variance was 14.1%. Therefore, we need differentiated clinical practice stress reduction programs according to gender and various strategies that can enhance major satisfaction in order to reduce the clinical practice stress of nursing students.

• The Journal of the Korea Contents Association
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• v.21 no.3
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• pp.301-313
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• 2021

This study was conducted on 253 artists for a month from April 19, 2020 to study the influence and countermeasures of COVID-19. The analysis results are as follows. First, as a result of frequency analysis, the timing of the occurrence of COVID-19 and the period of the decrease in artist's artistic activities were consistent, and the subjective socioeconomic level perceived by the artist was degraded from COVID-19. Second, as a result of the multivariate variance analysis, the income level and employment environment of artists affected the variables associated with COVID-19. Third, as a result of the hierarchical analysis analysis, the income level and the socioeconomic level changes due to COVID-19, and concerns about COVID-19 infections, have been shown to have had a significant impact on the level of stress felt by artists. Fourth, as a result of qualitative research, the artist reported that he was experiencing economic and psychological difficulties due to the influence of COVID-19, and emphasized the need for policy support as a way to cope with them. We hope that the results of this study will be used as empirical data in the process of developing support systems and programs for artists experiencing economic constraints and social alienation due to COVID-19.

• Journal of Korean Tunnelling and Underground Space Association
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• v.24 no.1
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• pp.95-108
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• 2022

The increase in the use time of tunnel users due to the lengthening of the road tunnel may increase the evacuation time in case of fire, resulting in a large number of casualties. In order to reduce the casualties caused by fire, the "Road Tunnel Design Manual, Part 6 Tunnel" and "Road Tunnel Disaster Prevention Facility Installation and Management Guidelines" stipulate that ventilation facilities should be installed along with the extension of the tunnel. The ventilation system design factor considers the wind speed of the external natural wind to be at least 2.5 m/s, and it is applied upward according to the characteristics of the tunnel. As a result of analyzing the five-minute average wind speed data in the Daegwallyeong region for the past 6 years, it was analyzed that 15.8% of the windy days were winds of 10 m/s or more, and the maximum was 20 m/s. Therefore, in this study, when a fire occurs in a tunnel, the pattern of natural wind flowing into the tunnel and the backlayering distance of the tunnel fire smoke according to the maximum wind speed were analyzed. As a result, it was analyzed that a backflow of up to 490 m occurs when a gust of 20 m/s blows.

• Journal of the Korean Society of Floral Art and Design
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• no.45
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• pp.3-12
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• 2021

The 1-methylcyclopropene (1-MCP) is the gaseous ethylene action inhibitor, which delay senescence and wilting by blocking the binding of its receptors. We investigated the effects of 1-MCP with different treated duration (0h (Control), 1h, and 4h) in cut flowers of Eustoma grandiflorum 'Voyage' and Cymbidium 'Lapine Hat'. The relative water uptake increased by 14.5% than control (9.8%) and the flower diameter maintained high from 3 to 11 days in 1-MCP treatment for 4h in E. grandiflorum 'Voyage'. The relative fresh weight was averagely high in 1-MCP treatment for 4h, however, the vase life was not significantly different in both cut flowers. Since the effects of 1-MCP treatment was differently responded by plant species and cultivars, interacted studies of duration and levels of 1-MCP are needed for the pronounced effects of postharvest quality.

• Journal of Internet Computing and Services
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• v.23 no.2
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• pp.107-114
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• 2022

In this paper, availabilities of student-evaluations of team activities in the computer science basic classes were analysed. For the purpose, correlation analysis was conducted to investigate the relationships among peer-evaluation, self-evaluation, and academic achievement, and it was found that there was a statistically significant positive correlation among them. Moreover, the gap between peer-evaluation scores and self-evaluation scores was analyzed. When a one-sample t-test was performed, it was found that the gap was very significant. However, the size of the gap was not different between the two classes. That is, regardless of grade level, the students' self-evaluation scores tended to be on average higher than the evaluation scores received from peers. Finally, when analyzing the relationship between the gap in peer-evaluation and self-evaluation scores and academic achievement, there was no significant correlation between the gap in scores and academic achievement. In other words, there was no difference in the tendency of evaluation for students with high or low academic achievement. The results of the analysis shows the availability of student-evaluations of team activities in the evaluation of team-based instruction. The high correlation between self-evaluation and peer-evaluation indicates the objectivity of student-evaluation. Although it is clear that the self-evaluation score is higher on average than the score received from peers, it is more useful in terms of objectivity because it does not vary according to grade, subject, or academic achievement.

• Journal of Nutrition and Health
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• v.56 no.3
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• pp.288-299
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• 2023

Purpose: This study aimed to assess the weight fluctuations in college students during the coronavirus disease 2019 (COVID-19) pandemic and identify lifestyle and dietary changes related to weight gain. Methods: An online survey was conducted on 270 college students from September 22 to October 26, 2021. A logistic regression analysis was performed to analyze the relationship of weight gain with the general characteristics, lifestyle, and dietary changes of the students. Results: Among the respondents, 42.9% of men and 44.7% of women reported weight gain. The main reasons given for weight gain were reduced activities due to restrictions during lockdown and diet changes, mainly relating to delivered or fast foods. Among the general characteristics and lifestyle factors poor perceived health (odds ratio [OR], 3.97, 95% confidence interval [CI], 1.98-7.96) and being underweight (OR, 0.19, 95% CI, 0.05-0.83) were significantly associated with weight gain. With respect to the diet, increased frequency of eating breakfasts (OR, 4.44, 95% CI, 1.76-11.21), decreased frequency of eating snacks (OR, 0.35, 95% CI, 0.16-0.77), decreased frequency of fruit intake (OR, 3.0, 95% CI, 1.32-6.80), increased frequency of carbonated and sweetened beverage intake (OR, 2.74, 95% CI, 1.26-5.99) and increased frequency of fast food consumption (OR, 2.32, 95% CI, 1.14-4.70) were significantly associated with weight gain. Conclusion: The COVID-19 pandemic affected weight gain and caused lifestyle and dietary changes. Specific health and nutrition management plans should be prepared for handling future epidemics of infectious diseases based on the results of surveys conducted on larger sample size.