• The KIPS Transactions:PartB
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• v.16B no.2
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• pp.157-161
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• 2009

Minimum Letter Flips(MLF) and Weighted Minimum Letter Flips(WMLF) can perform the haplotype reconstruction more accurately from SNP fragments when they have many errors and gaps by introducing the related genotype information. And it is known that WMLF is more accurate in haplotype reconstruction than those based on the MLF. In the paper, we analyze two models under the conditions that the different rates of homozygous site in the genotype information and the different confidence levels according to the sequencing quality. We compare the performance of the two models using neural network and genetic algorithm. If the rate of homozygous site is high and sequencing quality is good, the results of experiments indicate that WMLF/GI has higher accuracy of haplotype reconstruction than that of the MCIH especially when the error rate and gap rate of SNP fragments are high.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.11
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• pp.1191-1198
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• 2015

In this paper, we develop simplified finite element (FE) models for butt-, lap- and T-welded joints by performing numerical and experimental experiments. Three-point bending tests of butt- and lap-welded specimens are performed to obtain the stiffness of the specimens and the strains at points near the welding beads. Similarly the stiffness and strains of T-welded specimen are measured by applying a point load at the end of the specimen. To develop simplified FE models, we consider the shape parameters of width, thickness and the angle of weld elements in the numerical simulations. The shape parameters of the simplified FE models are determined by building linear regression models for the experimental data sets.

• Journal of the Korean Geotechnical Society
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• v.29 no.9
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• pp.31-41
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• 2013

The use of energy pile foundation has increased for economic utilization of geothermal energy. In particular, coil-shaped ground heat exchanger (GHE) is preferred to the conventional U-shaped exchanger to ensure better efficiency of heat exchange rate. This paper presents a numerical and experimental study on the heat transfer behavior of PHC energy piles. Field thermal performance tests (TPTs) were conducted for the PHC energy piles installed in a partially saturated weathered granite soil deposit, in which two types of GHEs were considered: W and coil shaped GHEs. Besides, three-dimensional finite element analyses were also conducted, and the results were compared with the experimental results. According to the results of TPT and numerical analyses, the coil shaped GHE showed 10~15% higher heat exchange rate than the W type GHE in the PHC energy piles.

• Korean Journal of Microbiology
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• v.47 no.4
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• pp.323-327
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• 2011

Fecal specimens from acute gastroenteritis in Seoul from 2009 to 2010 were collected and then tested for the presence of Group A Rotavirus by ELISA. Among a total of 1,916 samples investigated, 354 samples (18.4%) were positive. The predominant genotypes of positive samples were confirmed as P6G[4] (35%), P8G[3] (28%), P8G[1] (24%), P4G[2] (10%), P8G[9] (3%), respectively. Among a total of 70 ground water samples investigated, 2 samples (2.8%) were positive. The genotypes of positive samples were confirmed as P8G[3] (100%). By this molecular investigation, genotypic distribution associated with rotavirus will be used for control and prevention of rotavirus related diseases.

• Horticultural Science & Technology
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• v.34 no.1
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• pp.134-141
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• 2016

The DNA marker T1ex, originally developed from melon (Cucumis melo L.) for monoecy, was employed in chamoe, which is referred to as oriental melon. This marker shows size variations in monoecious melon. However, in chamoe, no such detrimental size variation was found in monoecious chamoe, and 99% association between flower phenotypes and genotypes of the T1ex marker was observed in 106 lines of chamoe. To evaluate the efficacy of the T1ex marker for marker-assisted selection (MAS), a total of 240 plants of chamoe breeding lines were screened using the T1ex marker. Among these, 98 varieties were selected. Although the T1ex marker might not be useful for MAS in melon, we found 100% concordance between genotypes and phenotypes for sex expression in chamoe. These results suggest that the T1ex marker will be a useful resource for MAS for monoecy in chamoe.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.5
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• pp.10-19
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• 2022

Irregularity in structural shape is a ubiquitous phenomenon. Structural hazards evoked from irregularity need to be checked against extreme lateral loadings. Structures containing four distinct types of irregularities in terms of continuity and discontinuity in upper half-length and all story levels along with O-shape are investigated. The structures were analyzed numerically and different seismic responses such as displacements, bending moment, axial forces, torsions, story drift, etc. were scrutinized. The seismic and wind load analysis was conducted for ACI 318-11 conditions. Results show that buildings having discontinuous beams on the upper half exhibit better resilience. It is also concluded that O-shaped building structures provide better resistance to overturning, making this shape relatively safe.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.22 no.4
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• pp.35-40
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• 2022

This paper proposes an antenna that is located outside the PCB substrate of an electronic product to enable wireless communication in the ISM band. The PCB designed the T-shaped OPEN-STUB power supply line to be miniaturized so that it does not interfere with parts or interfere with design. The characteristics of the antenna were confirmed in the 2.4GHz and 5.8GHz bands using a T-shaped stub feeder and a spiral structure. The size of the antenna is 5mm in width × 6.5mm in length, and the thickness of the PCB is 1.2T. As a result of measurement of the manufactured antenna, it was possible to obtain a return loss of -10dB or more at 2.4GHz and 5.8GHz. In the E-plane, the gain was -4.45 dBi, and in the H-plane, the gain was -1.05 dBi. Therefore, the proposed small antenna for wireless communication showed excellent performance.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.3
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• pp.211-215
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• 1994

Lipoxygenase is involved in the formation of certain undesirable flavors of soybean products. Three isozymes(L-1, L-2 and L-3) of lipoxygenase have been identified in soybean seeds, and the three types of mutants lacking L-1, L-2 and L-3, respectively, were detected in the 1980's. In this paper, lipoxygenase activity was measured to investigate the response of lipoxygenase in organs and tissues during soybean development. There was no tendency according to genotypes between lipoxygenase lacking mutants and normal soybeans in lipoxygenase activity of leaf at $V_3$ and $V_5$ stage. Likewise, pod wall lipoxygenase was no difference among genotypes tested at R$_{6}$ stage. Seed coat lipoxygenase activity was similar among the lipoxygenase lacking mutants, while normal soybean was lower as compared with that of the lipoxygenase lacking mutants. Embryo and cotyledon lipoxygenase activity in the lipoxygenase lacking mutants was much lower than that of normal soybean, also there was large difference among lipoxygenase lacking mutants. Thus, the lipoxygenase null mutant showed very weak value although the lacking L-3 mutant had a large effect on developing embryo lipoxygenase activity. It was suggested that soybean lipoxygenase isozymes expressed in embryo may be different from those expressed in the pod wall and leaf tissues.

• Pediatric Infection and Vaccine
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• v.6 no.2
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• pp.219-233
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• 1999

Purpose : Respiratory syncytial virus(RSV) is the major cause of lower respiratory tract infection in infants and young children. This study was performed to analyze antigenic and genetic variation of G protein of subgroup A RSV. Methods : One hundred seventy-nine strains isolated at the Seoul National University Children's Hospital over 8 years-period from 1990 through 1998 were analysed for antigenic and genetic variability. Analysis was made by reactivity with monoclonal antibodies raised against RSV, and by restriction mapping and, for selected strains, nucleotide sequencing following amplification of full sequence of G gene by reverse transcription-polymerase chain reaction. Results : Restriction fragment analysis of the amplified G protein gene revealed 23 restriction patterns, 12 of which included more than 2 isolate, and the most frequent genetic type comprised 30% of the strains. Indirect immunofluorescent staining with monoclonal antibodies revealed 6 antigenic types with one predominant pattern accounting for 91% of the total strains. The most frequent antigenic type had 21 restriction patterns, and some viruses with same restiction pattern had different monoclonal antibody reaction pattern. Nucleotide sequence homology of subgroup A was 91~93% between reference(A2, Long) and Korean isolates, 93~99% among Korean isolates. Maximum-parsimony analysis demonstrated that Korean isolates were distinct from reference strains and subgroup A strains were clustered in 4 groups. Conclusion : The restriction analysis pattern of G protein gene identified greater diversity within subgroup A than was seen with the monoclonal analysis and a variety of antigenic and genetic types of RSV are circulating in Korea which are different from reference strains or strains isolated from other countries.

• Journal of Life Science
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• v.19 no.2
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• pp.234-240
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• 2009

We tried to analyze the HPV prevalence and HPV genotypes of sexually high-risk women living in Busan, the biggest seaport of South Korea. Six hundred sixty women engaging in high-risk occupations participated in this study. The prevalence of HPV infection and HPV genotyping were determined with $MyGene^{(R)}$ HPVDNA chip, which consisted of 16 high-risk HPV genotypes (oncogenic genotypes) and 8 low-risk HPV genotypes. The overall prevalence of HPV infection in this study population was 39.1% (258/660) and the 20's showed the highest prevalence of HPV infection (51.5%). The dominant HPV genotypes including single or multiple HPV-infected women were resulted in HPV-16 (15.9%), -53 (10.2%), -58 (7.7%), -18 (5.2%) in case of high-risk HPV genotype and HPV-70 (10.4%), -6 (4.1%), -11 (2.0%) in case of low-risk HPV genotypes. Remarkably, the proportion of women infected with high-risk HPV genotypes (62.0%) was almost four times higher than those of women infected with low-risk HPV genotypes (14.7%) and high/low-risk HPV genotypes (12.0%). Among the 258 HPV-infected women, single infection was 175, double infection 66, triple infection 12, quadruple infection 4, quintuple infection 1, respectively. Our finding suggests that the introduction and development of effective HPV vaccines should consider the current status of HPV genotypic infection in South Korean women.