• Proceedings of the Korean Society of Developmental Biology Conference
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• 1998.07a
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• pp.36-38
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• 1998

생쥐 자궁의 조직세포는 생식주기와 초기 임신시기동안 $\beta$ -galactosidase mRNA를 지속적으로 발현하며, 이로부터 합성 및 분비되는 $\beta$ -galactosidase 단백질의 발현과 활성은 자궁의 조직추출액에서는 생식주기 중 proestrus시기에, 자궁내액에서는 diestrus시기에 가장 높게 나타났고 임신 1일째부터 4일째의 기간동안에는 임신이 진행될수록 점점 더 높게 나타났다. 이러한 결과로 미루어 $\beta$ -galactosidase는 생쥐의 생식 활동 즉, 생식 주기동안의 자궁 조직세포의 분화와 임신 초기 배아의 자궁 내막에의 착상에서 중요한 역할을 하는 것으로 사료된다.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.625-632
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• 2024

The purpose of the study was to find out the novice mothers' perceptions, experiences, and need on healthy pregnancy. For the research purpose, we conducted the focus group interview with 10 novice mothers who were pregnant of their first child or raising first child under 12 months old. The results of the study were as follows. First, novice mothers recognized 'healthy pregnancies' as 'physically healthy pregnancies for mothers and fetuses,' 'pregnancies where mothers were mentally healthy and happy,' and 'pregnancy planned and prepared with husband together.' Second, novice mothers experienced 'examination of obstetrics and gynecology,' 'management of health and daily life,' and 'preparation of realistic conditions' to prepare for pregnancy and childbirth. Third, difficulties during pregnancy were due to 'sickness and physical changes' and 'psychological and emotional changes.' Fourth, the needs on support for healthy pregnancy were 'pre-education on mental and physical changes caused by pregnancy' and 'support for pregnancy and counseling in advance.'

• Journal of dental hygiene science
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• v.9 no.2
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• pp.231-239
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• 2009

The study distributed the total 210 questionnaires to women of childbearing age in Seoul, Gyeonggi and North Chungcheng from March 26, 2008 to April 16, 2008 and made them draw up them directly. The study applied 208 copies excepting two copies not suitable to data process to data analysis. The purpose of the study was to investigate/analyze awareness of dental treatment, oral health conditions and oral health management during the period of pregnancy and to serve the analyzed data as basic data of oral health education program development to improve expectant mothers' behaviors of oral health management: 1. According to the survey by age with regard to a question 'Should expectant mothers take dental treatment during the period of pregnancy?', women of 18~29 years old (41.9%) and more than 50 years old (52.0%) answered 'They should not take dental treatment'. Women of 30~39 years old (53.6%) and 40~49 years old (54.7%) answered 'They should take dental treatment'. According to pregnant experience, expectant mothers (63.9%) and women with their parity (46.3%) answered 'They should take dental treatment'. 34.8% women without their parity answered 'They should take dental treatment' and 34.8% women with Out their parity answered 'They should not take dental treatment'(p < 0.05). 2. According to the survey by age with regard to a question 'Do you brush your teeth lifter having morning sickness during the period of pregnancy?', women of 18~29 years old (67.3%), 30~39 years old (47.3%) answered 'Brush my teeth' and women of 40~49 years old (51.0%) and more than 50 years old (52.0%) answered 'Don't brush my teeth'(p < 0.001). According to pregnant experience, expectant mothers (72.2%) and women with their parity (43.0%) answered 'Brush my teeth'(p < 0.05). 3. With regard to a question 'Are oral aid hygiene supplies required?', women of 18~29 years old (47.3%) and 30~39 years old (46.4%) answered 'Required' and women of 40~49 years old (41.5%) and more than 50 years old (48.0%) answered 'do not know'(p < 0.05). 4. According to the survey by age with regard to a question 'What are you anxious about during the period of dental treatment?', women of more than 50 years old (56.0%) answered 'Expenses' and women of 18~29 years old (39.2%), 30~39 years old (44.6%) and 40~49 years old (41.5%) answered 'Pain'(p < 0.05). According to pregnant experience, expectant mothers answered 'Pain (38.9%), abort ion (27.8%) and expenses (22.2%)' and women with their parity, answered 'Pain (45.0%), expenses (22.8%) and abortion (14.8%). Women without their parity answered 'Expenses (52.2%) and pain (13.0%)'(p < 0.05).

• Journal of the Korean Society of Radiology
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• v.15 no.4
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• pp.499-505
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• 2021

In this study, HRV signals are analyzed to compare the autonomic nervous system activity of non-pregnant women and pregnant women. 99 disease-free pregnant women and 27 non-pregnant women from W Hospital participated in the study. The acquired HRV signals were used by the program to perform time domain analysis and frequency domain analysis. The measured values were statistically analyzed for differences between pregnancy periods through a one-way ANOVA. In the results, SDNN and RMSSD in time domain analysis had significantly higher results in early pregnancy and non-pregnant women compared to mid- and late pregnancy. In frequency domain analysis, LF and HF had significantly higher values for pregnancy and non-pregnancy compared to midand late-term, but there was no significant difference between VLF and LF/HF. his means that as pregnancy progresses, the ability to control autonomous nerves decreases in the middle and late stages of pregnancy and increases physical fatigue and mental fatigue. Therefore, the longer the pregnancy period, the more special care is needed to maintain mental and physical stability of pregnant women.

• Journal of Nutrition and Health
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• v.44 no.1
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• pp.5-15
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• 2011

Although iron is an essential mineral, excess iron intake during pregnancy may increase oxidative stress in tissues. This study was conducted to investigate the effects of iron overload during pregnancy on iron status and oxidative stress in maternal rats. Ten week-old female Sprague-Dawley rats were mated with male rats. Non-pregnant (control) and pregnant rats were fed diets containing normal Fe (35 mg/kg diet), high Fe (350 mg/kg diet), or excess Fe (1,050 mg/kg diet) during pregnancy. Rats were sacrificed on pregnancy day 19. No significant difference in weight gain, diet intake, or litter size was observed according to iron intake levels. Furthermore, serum iron, hemoglobin, and hematocrit were not different among the rats administered the three levels of Fe both in the control and pregnant groups. However, the iron levels were lower in pregnant rats than those in the control. The liver and spleen iron contents increased significantly in the excess Fe group. An increase in liver ferritin levels with increasing iron intake was observed. Protein carbonyl content, as a marker of oxidative stress, increased significantly in liver with increasing iron intake but not malondialdehyde. Glutathione peroxidase activity in the liver of pregnant rats fed excess iron decreased significantly. Bcl-2 protein expression in the liver declined remarkably with increasing maternal iron intake in pregnant rats. Taken together, iron overload during pregnancy had little effect on hematology. However, the deposits of iron in the liver and the decline in antioxidant enzyme activity implied increased oxidative stress in tissues of the excess Fe group. These results suggest that excess iron intake during pregnancy increases oxidative stress in maternal tissues and may also affect fetal tissues.

• Clinical and Experimental Reproductive Medicine
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• v.18 no.2
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• pp.133-142
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• 1991

This study was carried out to observe the change in uterine cyclic nucleotide level and the effect of PAF on cyclic nucleotides in uterine tissue in early pregnany in order to understand reciprocal relation ship between PAF and cyclic nucleotides in pregnancy in the rat. The test groups were injected intramuscularly with $1{\mu}g$ of PAF or 1.25mg of BN-52021 on day 0, 1, 2, 3, 4 and 5 of pregnancy. The level of cyclic nucleotide in removed uterine tissue was assayed by using cyclic nucleotides test kits. The results showed that the cyclic AMP content in uterine tissue of non-pregnant at pro-oestrus rat was $2.91{\pm}0.33$ pmol/mg protein which was lower than those of pregnant rat. The cyclic GMP content in uterine tissue of non-pregnant rat was $0.39{\pm}0.20$ pmol/mg pro-tein which was also lower than those of pregnant rats. The maximum level in cAMP was $5.92{\pm}1.72$ pmol/mg protein on day 3 and cGMP, $1.03{\pm}0.22$ pmol/mg protein on day 4. On each day of pregnancy, PAF induced the increased cAMP level ompared with that of intact rat. That was significant on day 0, 2 and 4 of pregnancy, p<0.05, on the other hand PAF receptor antagonist, BN-52021 ecreased cAMP level in uterine tisssue. PAF as well as BN-52021 had not an consistent effect on changes in cGMP level. These results suggest that cyclic nucleotide levels in uterine tissue ware increased during early pregnancy and PAF influences cAMP level in uterine rather than cGMP level during peri-implantation period, accordingly demonstrating a possible involvement of PAF in the regulation of implantation-related events through cAMP-mediated process.

• Proceedings of the Korean Nutrition Society Conference
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• 2004.05a
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• pp.145-145
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• 2004

• Journal of Korean Medical Ki-Gong Academy
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• v.7 no.2
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• pp.1-17
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• 2004

• The Korean Nurse
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• v.24 no.5 s.133
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• pp.52-60
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• 1986

• Journal of Yeungnam Medical Science
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• v.16 no.1
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• pp.131-136
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• 1999

자궁경관 임신은 최근에 인공유산의 증가와 인공 보조 생식술(assisted reproductive technology) 등에 의하여 증가되는 양상을 보인다. 과거에는 자궁경관 임신은 대량의 무통성 질출혈로 진단을 내리고 치료 방법은 천자궁적출술이 유일한 수단이었으나, 지금은 질식 초음파의 개발로 자궁경관 임신을 조기에 진단하고 자궁 보존적 방법으로 치료하여 차후 임신을 기대할 수 있게 되었다. 그 치료 방법 중 하나로 Methotrexate(MTX)를 주사하여 성공적으로 치유된 많은 보고들이 있었다. 본 저자들은 임신 8주에 자궁경관 임신으로 진단된 환자에서 전신적 MTX 투여와 복식 초음파 관찰 하에 양막강내 MTX 투여 병합 요법으로 치료한 1례를 보고하고 치료과정에서 자궁경부 병변의 지연 관해에 대해서 문헌 고찰과 함께 보고하는 바이다.