• Title/Summary/Keyword: 응용개발

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A pattern of cell death induced by 40 kHz ultrasound in yeast cell model (40 kHz 초음파에 의해 유도된 효모세포 모델에서 세포사멸 패턴)

  • Kim, Ji Wook;Kong, Hee Jeong;Kim, Young H.;Kang, Kwang Il
    • The Journal of the Acoustical Society of Korea
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    • v.36 no.3
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    • pp.172-178
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    • 2017
  • Ultrasound has been widely used for biological and medical applications including induction of cell death, but a precise mechanism of induced cell death by ultrasound is controversial. In this study, an irradiation system with 40 kHz ultrasound was developed for a suitable cell death test of a representative unicellular organism, yeast, and used to study the biological effect of ultrasound on inducing cell death. Potassium Iodide (KI) dosimetry was used to devise an optimal system that successfully delivers 40 kHz ultrasound and produces reactive oxygen species in a 1.5 ml Eppendorf tube. Cell death was observed in an ultrasound transmission time-dependent fashion in this system. Thermal effect during irradiation was not observable in ultrasound induced cell death. Co-treatment of 40 kHz ultrasound and hydrogen peroxide showed a synergistic effect in inducing cell death. This finding suggests that 40 kHz ultrasound is related to reactive oxygen species formation. However, NAC (N-acetyl-L-cysteine) oxygen scavenger slightly inhibited the cell death by 40 kHz ultrasound. It was also found that 40 kHz ultrasound induced cell death was slightly inhibited by inhibitors of necrosis or apoptosis (glycyrrhizin or zVAD-fmk). This study suggests that cell death induced by 40 kHz ultrasound may not be exclusively related to reactive oxygen species formation and thermal effects in irradiated yeast cells.

Structure of Data Fusion and Nonlinear Statistical Track Data Fusion in Cooperative Engagement Capability (협동교전능력을 위한 자료융합 구조와 비선형 통계적 트랙 융합 기법)

  • Jung, Hyoyoung;Byun, Jaeuk;Lee, Saewoom;Kim, Gi-Sung;Kim, Kiseon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.1
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    • pp.17-27
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    • 2014
  • As the importance of Cooperative Engagement Capability and network-centric warfare has been dramatically increasing, it is necessary to develop distributed tracking systems. Under the development of distributed tracking systems, it requires tracking filters and data fusion theory for nonlinear systems. Therefore, in this paper, the problem of nonlinear track fusion, which is suitable for distributed networks, is formulated, four algorithms to solve the problem of nonlinear track fusion are introduced, and performance of introduced algorithms are analyzed. It is a main problem of nonlinear track fusion that cross-covarinaces among multiple platforms are unknown. Thus, in order to solve the problem, two techniques are introduced; a simplification technique and a approximation technique. The simplification technique that help to ignore cross-covariances includes two algorithms, i.e. the sample mean algorithm and the Millman formula algorithm, and the approximation technique to obtain approximated cross-covariances utilizes two approaches, by using analytical linearization and statistical linearization based on the sigma point approach. In simulations, BCS fusion is the most efficient scheme because it reduces RMSE by approximating cross-covariances with low complexity.

A Study on Desing Simplification of Yoke Crank in a γ-type Stirling Engine (γ-type Stirling Engine의 Yoke crank 설계 단순화에 관한 연구)

  • Kim, Shin-Hyo;Kim, Ui-Chang;Bark, Jin-Jae;Bae, Han-Nah;Cho, Dae-Kweon
    • Journal of Advanced Marine Engineering and Technology
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    • v.39 no.4
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    • pp.405-411
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    • 2015
  • Recently, according to the low-carbon green growth policy, the Stirling Engine has been increasing the interest of some sort of external combustion engines Stirling Engine is largely divided into three types ${\alpha}$, ${\beta}$ and ${\gamma}$. Among them, a ${\gamma}$-type engine is easy to design and can be applied variously. However, owing to the connection distance between the cylinder and the crank, there was a problem that ${\gamma}$-type occupies a larger volume than the ${\alpha}$ and ${\beta}$-types. As one of the methods to solve this problem, we have to consider about the Yoke crank which have been applied mainly to the ${\alpha}$-type. Because there are two advantages in not only reduction of engine volume but also parallelizing the cylinder. In this study, leading on from the existing design techniques for the Ross Yoke crank, this paper presents a simple method that can apply the yoke crank design of the ${\gamma}$-type stirling engine.

Fog Collection/Removal System Using a Moss Filter (이끼필터를 이용한 안개 포집/제거 시스템)

  • Oh, Sunjong;Park, Minyong;Kim, Wandoo;Lim, Hyuneui
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.40 no.7
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    • pp.449-455
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    • 2016
  • Fog causes economic losses in transportation. It also results in health problems when it is combined with air pollutants. Considerable research efforts have focused on developing fog removal systems. However, most systems operate themselves after monitoring the fog. Additionally, continuous energy supply and maintenance are required to retain the fog-removal efficiency of the system. This study included the demonstration of a moss filter (a polyolefin mesh interlaced with moss) as a fog-removal method overcoming the limitations of the fog removal system. Three types of mosses with different surface structures were investigated to elucidate the relation between the moisture absorption rate and the structures. Among the different moss types, Hypopterygium japinicum showed the highest efficiency based on the smallest pore diameter and the largest total pore area. The visibilities with the moss filter and the polyolefin mesh were compared to perform the fog removal tests. The moss filter could provide a cost-effective and eco-friendly fog removal system with sustainability.

Development of Rotordynamics Program Based on the 2D Finite Element Method for Flywheel Energy Storage System (2차원 유한요소법을 적용한 플라이휠 에너지 저장 장치 동특성 해석 프로그램 개발)

  • Gu, Dong-Sik;Bae, Yong-Cae;Lee, Wook-Ryun;Kim, Jae-Gu;Kim, Hyo-Jung;Choi, Byeong-Keun
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.11
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    • pp.1757-1763
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    • 2010
  • Flywheel energy storage system (FESS) is defined as a high speed rotating flywheel system that can save surplus electric power. The FESS is proposed as an efficient energy storage system because it can accumulate a large amount of energy when it is operated at a high rotating speed and no mechanical problems are encountered. The FESS consists of a shaft, flywheel, motor/generator, bearings, and case. It is difficult to simulate rotor dynamics using common structure simulation programs because these programs are based on the 3D model and complex input rotating conditions. Therefore, in this paper, a program for the FESS based on the 2D FEM was developed. The 2D FEM can model easier than 3D, and it can present the multi-layer rotor with different material each other. Stiffness changing of the shaft caused by shrink fitting of the hub can be inputted to get clear solving results. The results obtained using the program were compared with those obtained using the common programs to determine any errors.

On the Attractive Teaching Methods of Mathematics with Parents of Students (학부모와 함께 하는 흥미로운 수학지도 방안)

  • Park, Hyung-Bin;Lee, Heon-Soo
    • Journal of the Korean School Mathematics Society
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    • v.10 no.4
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    • pp.455-469
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    • 2007
  • In this study, we want to being helpful to improvement of ability to solve mathematical problem, that is grafted on the subjects being able to occur in real life, of students in teaching materials and results studied and developed in the university. For increasing ability to solve ingenious problem and growing in the learning ability of oneself leading of students. The goal of this study is to make possible open research as a result of that students look for problem around real life by one's own efforts and take interest in them through learning mathematics of parents of students, they are the most important fact of educational environment in the mathematics education - earlier than students. In particular, the goal of this study is that students have an positive attitude of mind for mathematics and maximize ability of practical application by the analytic thinking learned through experience of their parents, they survey, analyze and solve problems taken from real life in the method transmitting one's knowledge to others. This study is divided into 2 categories: education of students and education of their parents. By these, we want to disseminate advanced knowledge and theory through students improve the powers of thought, logic and inference, develop ability to solve mathematical problem, stir up motivation of learning and learn knowledge of mathematics become familiar with real life.

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A Study of a Module of Wrist Direction Recognition using EMG Signals (근전도를 이용한 손목방향인식 모듈에 관한 연구)

  • Lee, C.H.;Kang, S.I.;Bae, S.H.;Kwon, J.W.;LEE, D.H.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.7 no.1
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    • pp.51-58
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    • 2013
  • As it is changing into aging society, rehabilitation, welfare and sports industry markets are being expanded fast. Especially, the field of vital signals interface to control welfare instruments like wheelchair, rehabilitation ones like an artificial arm and leg and general electronic ones is a new technology field in the future. Also, this technology can help not only the handicapped, the old and the weak and the rehabilitation patients but also the general public in various application field. The commercial bio-signal measurement instruments and interface systems are complicated, expensive and large-scaled. So, there are a lot of limitations for using in real life with ease. this thesis proposes a wireless transmission interface system that uses EMG(electromyogram) signals and a control module to manipulate hardware systems with portable size. We have designed a hardware module that receives the EMG signals occurring at the time of wrist movement and eliminated noises with filter and amplified the signals effectively. DSP(Digital Signal Processor) chip of TMS320F2808 which was supplied from TI company was used for converting into digital signals from measured EMG signals and digital filtering. We also have used PCA(Principal Component Analysis) technique and classified into four motions which have right, left, up and down direction. This data was transmitted by wireless module in order to display at PC monitor. As a result, the developed system obtains recognition success ratio above 85% for four different motions. If the recognition ratio will be increased with more experiments. this implemented system using EMG wrist direction signals could be used to control various hardware systems.

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New Cosmetic Agents for Anti-aging from Zostera marina L. (잘피(Zostera marina L.)의 신규 항노화 화장품 소재 응용)

  • Jin-Hui, Kim;Kyung-Eun, Lee;Jin-Hwa, Kim;Young-Ho, Cho;Sung-Min, Park;Jeong-Jae, Lee;Bum-Chun, Lee;Hyeong-Bae, Pyo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.2
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    • pp.235-240
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    • 2004
  • In order to develop new anti-photoaging agents from marine natural products, Zostera marina L. was selected for its antioxidative activity and inhibition of matrix metalloproteinase-1 (MMP-1) expression. Three compounds (compounds 1, 2, and 3) were isolated from the extract, and they were identified as apigenin-7-O-${\beta}$-D-glucoside (1), chrysoeriol (2), and luteolin (3). These compounds have SC$\_$50/ values of 0.18 mM, 0.68 mM, and 0.01 mM against l,l-dipheny1-2-picrylhydrazyl radical and 0.04mM, 0.03mM, and 0.01mM against the superoxide radical in the xanthine/xanthine oxidase system, respectively. Compound 3 suppressed the expression of MMP-1 by up to 44% at 35.0${\mu}$M and inhibited the production of interleukin 6, which is known as a cytokine that induces MMP-1 expression. In addition, the wrinkle improvement effect of the formulation with Z. marina extract was measured. As a result, remarkable reduction was found in the fine wrinkle and skin roughness after application of the cream with 3.0% this extract for 8 weeks. In conclusion, the isolated compounds from Z. marina extract were good antioxidant and suppressor of MMP-1 expression and the formulation with the extract diminished the skin wrinkle. Therefore, the extract can be used as a new anti-aging agent for application in cosmetic.

A Study on the Surface-Modification of Barium Sulfate/TiO$_2$/Dimethicone Composite Powder and its Application in Color Cosmetics (바륨설페이트/티타늄디옥사이드/디메치콘의 복합화 및 메이크업에서의 응용)

  • Kyung-Ho, Choi;Seung-Yong, Ko;Hak-Hee, Kang;Ok-Sub, Lee
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.2
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    • pp.197-200
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    • 2004
  • Sensor and optical properties have become critical features in powder foundation. The flaky barium sulfate powder shows good smooth texture, adhesion and natural looking characteristics. However, it has limitations abilities in UV shielding, hiding and blooming effect. Thus we adopt TiO$_2$ that has excellent hiding power and blooming effect as well as UV shielding ability, but TiO$_2$ has still intrinsic problems in dispersion and texture. To overcome this disadvantages, the barium sulfate/TiO$_2$/dimethicone composite powder was prepared. The flaky barium sulfate powder was coated with TiO$_2$ in nanoscale and followed by coated with dimethicone. When this surface-modified powder was applied for make-up cosmetics, especially in powder foundation, the powder gave powder foundation more good characteristics than the original flaky barium sulfate, Ti02 powder, dimethicone in abovementioned optical and sensory properties. To characterize the distinctive features of this surface-modified powder, we measured its characteristics with UV in vitro tester, hiding powder test method, goniophotometer, consumer panel test and so on.

Chemical Composition and Biological Activities of Essential Oil from 'Setoka' Branches (세토카 가지 정유의 성분 분석 및 생리 활성)

  • Hyun, Ju Mi;Kim, Jung Eun;Yeum, Hyun Sook;Song, Jung-Min;Kim, Mi Ryang;Lee, Nam Ho
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.3
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    • pp.227-233
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    • 2016
  • This study was designed to analyze the chemical compositions of 'Setoka' branch essential oils (SEBO) and to test their biological activities. 'Setoka' is a Citrus species widely cultivated in Jeju Island. At the present, 'Setoka' branches produced by thinning process were mostly discarded as a waste. Therefore, utilization of this branch waste has received much attention. 'Setoka' branch essential oils (SBEO) were prepared by treatment of its ethanol extracts with jojoba oil. SBEO were chemically analyzed using gas chromatograph-mass spectrometry (GC-MS), and following components were identified; ethyl linoleate (64.14%), ethyl palmitate (16.50%), neophytadiene (11.06%) and beta-citronellol (5.09%). The anti-inflammatory activity in the SBEO was examined using RAW 264.7 murine macrophage cells stimulated with LPS. As a result, the SBEO inhibited nitric oxide (NO) productions with a dose-dependent manner. In addition, SBEO showed good anti-microbial activities against drug-susceptible and -resistant skin pathogens such as Staphylococcus aureus and Propionibacterium acnes, which are acne-causing bacteria. Based on these results, we suggest that SBEO has the possibility for use as an anti-inflammatory and anti-microbial agent in cosmetic applications.