• Title/Summary/Keyword: 유전적 구조

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An Improved Function Synthesis Algorithm Using Genetic Programming (유전적 프로그램을 이용한 함수 합성 알고리즘의 개선)

  • Jung, Nam-Chae
    • Journal of the Institute of Convergence Signal Processing
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    • v.11 no.1
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    • pp.80-87
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    • 2010
  • The method of function synthesis is essential when we control the systems not known their characteristic, by predicting the function to satisfy a relation between input and output from the given pairs of input-output data. In general the most systems operate non-linearly, it is easy to come about problem is composed with combinations of parameter, constant, condition, and so on. Genetic programming is proposed by one of function synthesis methods. This is a search method of function tree to satisfy a relation between input and output, with appling genetic operation to function tree to convert function into tree structure. In this paper, we indicate problems of a function synthesis method by an existing genetic programming propose four type of new improved method. In other words, there are control of function tree growth, selection of local search method for early convergence, effective elimination of redundancy in function tree, and utilization of problem characteristic of object, for preventing function from complicating when the function tree is searched. In case of this improved method, we confirmed to obtain superior structure to function synthesis method by an existing genetic programming in a short period of time by means of computer simulation for the two-spirals problem.

Genetic Diversity and Population Structure of Potentilla freyniana in Korea (한국내 세잎양지꽃의 유전적 다양성과 집단구조)

  • Huh, Man-Kyu
    • Journal of Life Science
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    • v.17 no.7 s.87
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    • pp.877-881
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    • 2007
  • The genetic diversity and population structure of Potentilla freyniana in Korea were determined using genetic variations at 19 allozyme loci. Thirteen of the 19 loci (68.4%) showed detectable polymorphism. Genetic diversity at the population level was high ($H_{EP}$ = 0.270). Total genetic diversity values ($H_T$) varied between 0.190 and 0.584, giving an average overall polymorphic loci of 0.371. The interlocus variation of genetic diversity within populations ($H_S$) was high (0.354). On a per locus basis, the proportion of total genetic variation due to differences among populations ($G_{ST}$) ranged from 0.008 for Fe-2 to 0.310 for Gpi with a mean of 0.065, indicating that about 6.5% of the total allozyme variation was among populations. Wide geographic ranges, perennial herbaceous nature and the persistence of multiple generations are associated with the high level of genetic variation in P. freyniana. The estimate of gene flow based on $G_{ST}$, was high among Korean populations of P. freyniana (Nm =3.57). Although P. freyniana usually propagated by asexually-produced ramets, I could not rule out the possibility that sexual reproduction occurred at a low rate because each ramet may produce terminal flowers.

Comparison and Validation of Genetic Diversity and Population Structure Using Monomorphic SNP Data of the Korean Native Black Goat and Crossbred Goat (재래흑염소와 교잡종 염소의 Monomorphic SNP 분석을 통한 유전적 다양성과 집단구조의 비교 및 검증)

  • Kim, Kwan-Woo;Lee, Jinwook;Lee, Eun-Do;Lee, Sung-Soo;Choi, You-Lim;Lim, Hyun-Tae;Kim, Yousam;Lee, Sang-Hoon
    • Journal of Life Science
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    • v.30 no.11
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    • pp.1007-1011
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    • 2020
  • This study was conducted to analyze the genetic diversity and relationships that discriminate between Korean native black goat populations (Dangjin, Jangsu, Tongyoung, and Gyeongsang National University strains) and crossbred goats. Monomorphic single nucleotide polymorphisms (SNPs) in each strain were collected, and 133 common SNPs were selected for analysis. These 133 monomorphic SNPs showed differences in the genetic structure of the Korean native black goat and crossbred goats, and results from the principal component analysis (PCA) showed that the two can be clearly separated. Furthermore, analysis of the validation population comprising 70 individuals (Korean native black goats, n = 24; crossbred goats, n = 46) with the reference population showed that Korean native black goat strains and the reference population have the same genetic structure, and the crossbred goats shared only part of the genetic structure with the reference population. The result of the PCA analysis showed that the Korean native black goat strains form one population, whereas the foreign strains form another population which is more widely dispersed than the Korean native black goat strains. Thus, the results from this study can be used as baseline data for the conservation of genetic resources of Korean native black goat communities through utilization of monomorphic SNPs and for the introduction of exotic species for further improvement in genetic diversity. This study can also help reduce unnecessary inbreeding and gene flow between native strains.

Genetic Diversity of the Slender Shinner(Pseudopuntungia tenuicorpa) and Its Conservational Implications (가는돌고기(Pseudopuntungia tenuicorpa) 보전을 위한 유전적 다양성 연구)

  • Kim, Dong-Young;Suk, Ho Young
    • Korean Journal of Ichthyology
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    • v.32 no.2
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    • pp.39-48
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    • 2020
  • The slender shinner (Pseudopungtungia tenuicorpa), a tiny freshwater fish of about 8 to 10 cm belonging to Cyprinidae, is an endangered species found only in the Han and Imjin Rivers on the Korean Peninsula. During the breeding season, this species spawns in nests of Coreoperca herzi, a predator of this species, or small crevices on rocks. This unique reproductive ecology can make this species more vulnerable to anthropogenic perturbance that can further limit the places to spawn. Here, mtDNA and microsatellite loci were analyzed to identify the genetic diversity and structure of slender shinners and further to provide the basic data necessary for the conservation planning of this species. A total of 28 polymorphic microsatellite markers were developed using Illumina paired-end sequencing, and 67 slender shinners collected from three localities in the Han River were genotyped using these loci. This species showed a remarkably high level of genetic diversity with mean expected heterozygosity of 0.914 and mean allele number per locus of 27.9, and no signature of drastic demographic decline was detected. As a result of our microsatellite analysis, the genetic structure between the two stems of the Han River, North Han and South Han, was prominent. Such a genetic structure was also evident in the sequence analysis of 14 haplotypes obtained from mtDNA control region. Although slender shinners are only found in very limited areas around the world, the genetic structure indicates that there is a block of gene flow among the populations, which should be reviewed in the future if management and restoration of this species is needed.

High-k 물질의 적층을 통한 고신뢰성 EIS pH 센서

  • Jang, Hyeon-Jun;Kim, Min-Su;Jeong, Hong-Bae;Lee, Yeong-Hui;Jo, Won-Ju
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.129-129
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    • 2011
  • ISFET (ion sensitive field effect transistor)는 용액 중의 각종 이온 농도를 측정하는 반도체 이온 센서이다. ISFET는 작은 소자 크기, 견고한 구조, 즉각적인 반응속도, 기존의 CMOS공정과 호환이 가능하다는 장점이 있다. ISFET의 기본 구조는 기존의 MOSFET (metal oxide semiconductor field effect transistor)에서 고안되었으며, ISFET는 기존의 MOSFET의 게이트 전극 부분이 기준전극과 전해질로 대체되어진 구조를 가지고 있다. ISFET소자의 pH 감지 메커니즘은 감지막의 표면에서 pH용액 속의 이온들이 감지막의 표면에서 속박되어 막의 표면전위의 변화를 유발하는 것을 이용한다. 그 결과, ISFET의 문턱전압의 변화를 일으키게 되고 드레인 전류의 양 또한 달라지게 된다. ISFET의 높은 pH감지능력을 얻기 위하여 높은 high-k물질 들이 감지막으로서 연구되었다. Al2O3와 HfO2는 높은 유전상수, non-ideal 효과에 대한 immunity 그리고 높은 pH 감지능력 등 많은 장점을 가지고 있는 물질로 알려졌다. 본 연구에서는, SiO2/HfO2/Al2O3 (OHA) 적층막을 이용한 EIS (electrolyte- insulator-silicon) pH센서를 제작하였다. EIS구조는 ISFET로의 적용이 용이하며 ISFET보다 제작 방법과 소자 구조가 간단하다는 장점이 있다. HfO2은 22~25의 높은 유전상수를 가지며 높은 pH 감지능력으로 인하여 감지막으로서 많은 연구가 이루어지고 있는 물질이다. 하지만 HfO2의 물질이 가진 고유의 특성상 화학적 용액에 대한 non-ideal 효과는 다른 금속계열 산화막에 비하여 취약한 모습을 보인다. 반면에 Al2O3의 유전상수는 HfO2보다 작지만 화학용액으로 인한 손상에 대하여 강한 immunity가 있는 재료이다. 이러한 물질들의 성질을 고려하여 OHA의 새로운 감지막의 적층구조를 생각하였다. 먼저 Si과 high-k물질의 양호한 계면상태를 이루기 위하여 5 nm의 얇은 SiO2막을 완충막으로서 성장시켰다. 다음으로 높은 유전상수를 가지고 있는 8 nm의 HfO2을 증착시킴으로서 소자의 물리적 손상에 대한 안정성을 향상시켰다. 최종적으로 화학용액과 직접적인 접촉이 되는 부분은 non-ideal 효과에 강한 Al2O3을 적층하여 소자의 화학적 손상에 문제점을 개선시켰다. 결론적으로 감지막의 적층 모델링을 통하여 각각의 high-k 물질이 가진 고유의 특성에 대한 한계점을 극복함으로써 높은 pH 감지능력뿐만 아니라 신뢰성 있는 pH 센서가 제작 되었다.

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Comparison for Genetic Diversity between Korean Native Commercial Chicken Brand Groups using Microsatellite Markers (Microsatellite Marker를 활용한 토종닭 브랜드 집단 간의 유전적 다양성 분석)

  • Lee, Hak-Kyo;Oh, Jae-Don;Park, Chan-Ho;Lee, Kun-Woo;Lee, Jun-Heon;Jeon, Gwang-Joo;Kong, Hong-Sik
    • Korean Journal of Poultry Science
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    • v.37 no.4
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    • pp.355-360
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    • 2010
  • To estimate the genetic characteristics within two brands of Korean native commercial chicken, we used a total of 302 genomic DNAs from two groups (Woorichicken: 152, Hanhyup3chicken: 150). Sizes of 10 microsatellite markers were decided using GeneMapper Software (v.4.0) after analyzing ABI 3130. Genetic diversity indices including expected heterozygosity (Ex H), observed heterozygosity (Ob H) and polymorphism information content (PIC). Frequencies of microsatellites markers were used to estimate heterozygosities and genetic distances. LEI0073 showed the highest value in all genetic diversity (Ex H, Ob H and PIC). On the other hand, MCW322 showed the lowest value in all genetic diversity. The calculated genetic distance of the two brand groups is 0.199 (standard genetic distance) and 0.132 (DA distance). Genetic distances of the two groups were relatively close to each other. Each individual is ramified to two brand groups in phylogenetic dendrogram.

Genetic diversity and population structure of Atractylodes japonica $K_{OIDZ}.$ in Korea (한국내 삽주의 유전적 다양성과 집단구조)

  • Huh, Man-Kyu;Sung, Jung-Sook;Park, Chun-Geon;Park, Hee-Woon;Seong, Nak-Sul;Moon, Sung-Gi;Huh, Hong-Wook
    • Korean Journal of Medicinal Crop Science
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    • v.10 no.1
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    • pp.5-11
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    • 2002
  • The study of genetic diversity was carried out in Atractylodes japonica $K_{OIDZ}$. Although this species has been regarded as medically important one, there is no report on population structure in Korea. Starch gel electrophoresis was used to investigate the allozyme variation and genetic structure of eight Korean populations of this species. Of the 15 genetic loci surveyed, nine (60.0%) was polymorphic in at least one population. Genetic diversity was high at the species level $(H_{es}=0.144)$, whereas, that of the population level was relatively low $(H_{ep}=0.128)$. Nearly 87% of the total genetic diversity in A. japonica was apportioned within populations. The sexual reproduction, high fecundity, and perennials are proposed as possible factors contributing to high genetic diversity. The indirect estimated of gene flow based on Gst was 1.69.

대기압 저온 플라즈마 발생 장치에 대한 연구

  • Kim, Yun-Jung;Han, Guk-Hui;Kim, Jung-Gil;Kim, Yeon-Jeong;Jo, Hyeon;Gang, Gyeong-Hun;Jo, Gwang-Seop
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.204-204
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    • 2016
  • 다양한 형태의 대기압 저온 플라즈마 장치를 개발하고 특성을 연구하였다. 최근 대기압 저온 플라즈마를 의료 및 미용 분야에 적용하기 위한 연구가 활발하게 진행되고 있다. 본 연구에서는 대기압 플라즈마 장치의 생체 적용을 위해 전기적, 열적 피해가 없는 플라즈마 발생 장치를 개발하였다. 대기압 플라즈마 발생 장치는 크게 플라즈마 제트와 유전 격벽 방전(DBD) 플라즈마의 형태로 나눌 수 있다. 대기압 플라즈마 제트는 고압 전극의 역할을 하는 주사 바늘과 바늘을 감싸고 있는 유리관, 유리관의 외부에 위치하는 접지 전극의 구조로 되어 있다. 방전 기체는 방전이 용이한 불활성 가스가 주로 사용되지만, 필요에 따라 $N_2$나 Air같이 방전이 어려운 분자 및 혼합 기체도 사용 한다. 방전 기체에 따라 대기압 플라즈마 제트의 전극 구조를 다르게 적용하였으며, 각 구조에서의 플라즈마 방전 특성을 연구 하였다. 유전 격벽 방전 플라즈마 장치는 고압 전극과 접지 전극 사이에 유전체가 위치하는 구조이다. 방전 가스를 불어주지 않아도 대기중에서 방전이 가능하고, 구조가 간단하여 용도에 맞는 다양한 형태로 방전이 가능하다. 이러한 대기압 저온 플라즈마의 특성 연구를 바탕으로 전기적, 열적 피해가 없으며 사용자 편의성을 갖춘 다양한 형태의 대기압 플라즈마 장치를 개발 하였다. 본 연구를 통하여 대기압 저온 플라즈마 발생 장치의 개발과 활용 연구에 도움이 될 것으로 기대한다.

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Genetic Diversity and Spatial Genetic Structure of Populus koreana Population in Mt. Odae, Korea (오대산 물황철나무(Populus koreana) 집단의 유전다양성 및 공간적 유전구조 분석)

  • Shin, Sookyung;Song, Jeong-Ho;Lim, Hyo-In;Jang, Kyung-Hwan;Hong, Kyung-Nak;Lee, Jei-Wan
    • Journal of Korean Society of Forest Science
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    • v.103 no.1
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    • pp.59-64
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    • 2014
  • This study describes analysis of genetic diversity and spatial genetic structure of Korean poplar (Populus koreana Rehder) in Mt. Odae using I-SSR markers. P. koreana is a deciduous broad-leaved tree species that primarily grows in the alpine valleys of China, Russia and North Korea. In South Korea, P. koreana is found limitedly in Gangwon province. Especially, the population in Mt. Odae is located on the southern limit line, its importance is emphasized from the genetic resource conservation perspective. The Shannon's diversity (I=0.230) and the expected heterozygosity (He=0.151) were relatively low as compared with those of other plant species. Spatial autocorrelation analysis using Tanimoto's distance showed that the genetic patch was founded within 400 m. It is suggested that individual trees for ex situ conservation should be sampled with a minimum distance of 400 m between trees.

The System Shape and Size Discrete Optimum Design of Space Trusses using Genetic Algorithms (Genetic Algorithms에 의한 입체트러스의 시스템 형상 및 단면 이산화 최적설계)

  • Park, Choon Wook;Kim, Myung Sun;Kang, Moon Myung
    • Journal of Korean Society of Steel Construction
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    • v.13 no.5
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    • pp.577-586
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    • 2001
  • The objective of this study is the development of sizing and system shape discrete optime design algorithm which is based on the genetic algorithms (GAs). The algorithm can perform both size and shape optimum designs of space trusses. The developed algorithm was implemented in a computer program. The algorithm is known to be very efficient for the discrete optimization The genetic process selects the next design points based on the survivability of the current design points The evolutionary process evaluates the survivability of the design points selected from the genetic process in the genetic process of the simple genetic algorithms there are three basic operators : reproduction cross-over and mutation operators. The efficiency and validity of the developed discrete optimum design algorithm was verified by applying the algorithm to optimum design examples.

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