• Title/Summary/Keyword: 유사성 회피

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Experimental Models of Schizophrenia (정신분열병의 실험적 모델)

  • Cheon, Jin-Sook
    • Korean Journal of Biological Psychiatry
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    • v.6 no.2
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    • pp.153-160
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    • 1999
  • Animal models can provide a useful tool for the study of some aspects of psychiatric disorders and their treatment. The four criteria for the evaluation of animal models of psychiatric disorders are as following : 1) similarity of inducing conditions 2) similarity of behavioral state 3) common underlying neurobiological mechanisms 4) reversal by clinically effective treatment techniques. Several animal models have been proposed for schizophrenia : phenylethylamine model, L-dopa model, hallucinogen model, cocaine model, amphetamine model, phencyclidine model, noradrenergic reward system lesion model, reticular stimulation model, social isolation model, conditioned avoidance reaction, catalepsy test, paw test, self-stimulation paradigms, latent inhibition paradigms, blocking paradigms, prepulse inhibition of the startle reflex, rodent interaction, social behavior in monkeys, hippocampal damage, high ambient pressure, and models using selective breeding. Among them, animals with bilateral lesion of the hippocampus may provide an adequate animal model for several symptoms of schizophrenia, and ketamine model can reproduce negative symptoms and cognitive deficits as well as positive symptoms of schizophrenia. In conclusion, no model of schizophrenia is entirely representative of the disease, and findings gleaned from model systems must be cautiously interpreted. Furthermore, the process of developing and validating animal models must work in concert with the process to identify reliable measures of human phenomenology.

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Land Use and Greenspace Structure in Seoul - Case of Kangnam-gu and Junglang-gu - (서울시의 토지이용 및 녹지구조 - 강남구 및 중랑구를 대상으로 -)

  • 조현길;이경재;권전오
    • Korean Journal of Environment and Ecology
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    • v.12 no.1
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    • pp.30-41
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    • 1998
  • This study analyzed urban greenspace area and vegetation structure by land use types for Kangnam-gu and Junglang-gu in Seoul different in income and building construction date. The study districts had a similar areal distribution of land use types. Residential lands accounted for about 32~37% of total area, natural lands, 19~22%, commercial and industrial lands(including transportation), 13~18%, and institutional lands, 13~17%. Greenspace covered only 20~30% of urban residential and commercial area in which human activities of living concentrate. Canopy stocking level in urban lands (all land uses except natural and agrecultural lands) was about 39% for Kangnam-gu and 50% for Junglang-gu, showing tree planting potential slightly higher in Kangnam-gu than in Junglang-gu. Woody plant cover was approximately 13%, and tree density was 3 trees/100m$^{2}$ forurban lands in both districts. The tree-age structure was largely characterized by young, growing tree population, and species diversity within a diameter class decreases as the diameter classes get larger. Urban lands of both districts had quite a similar species composition of woody plants (similarity indez of 0.70). Income and bulding construction date did not result in significant diference between the two districts in vegetation structure for urban lands. Some strategies were ezplored to solve problems found in the present greenspace structures. They included increase of biomass and greenspace area through minimization of unnecessary impervious surfaces, creation of multilayered and multiaged vegetation structures, and avoidance of intensive tree pruning and relocation of above ground utility lines.

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Differences in Eating Attitudes According to the Sensory Processing Characteristics of the Average Woman (일반 여성의 감각처리 특성에 따른 섭식 태도의 차이)

  • Moon, Gyu-Lahn;Lee, Chunyeop;Joo, A-Young;Kwak, Naim;Jung, Hyerim
    • The Journal of Korean Academy of Sensory Integration
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    • v.18 no.1
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    • pp.13-22
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    • 2020
  • Objective : This study was conducted to confirm general differences in eating attitudes according to the sensory processing characteristics of women. Methods : The Adolescent/Adult Sensory Profile (AASP) and the Eating Attitude Test (EAT-26) were used to survey 241 women. Their eating attitudes according to the sensory processing characteristics was analyzed using an independent t-test and one-way ANOVA, and the post-analysis was performed using the Scheffe test. Results : Among the sensory processing characteristics, except for eating control due to low registration, binge-eating and foodlessness due to sensory avoidance, all eating attitudes were significantly different according to sensory processing characteristics (p<.05). The anorexic behaviour, binge-eating and foodlessness was shown to be negative in cases of those who had much lower registration than most people. All eating attitudes, such as anorexia, binge-eating and foodlessness, and eating control, were shown to be negative in cases of women whose sensation seeking was equal to or much greater than the general population. The binge-eating and foodlessness were shown to be negative in cases of high sensory sensitivity. The anorexic behaviour was shown to be negative in cases of elevated sensory avoidance. Conclusion : Eating attitudes differed depending on the sensory processing characteristics. As such, sensory integration mediation can be proposed as a method of controlling the eating attitudes of women in general.

Pseudo-DC Resistivity Survey for Site Investigation at Urban Areas with Ambient Electrical Noises (전기잡음 간섭이 있는 도심지 지역 탐사를 위한 유사직류 전기비저항 기법)

  • Joh, Sung-Ho;Kim, Bong-Chan
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.1C
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    • pp.37-44
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    • 2010
  • Recently, urban retrofit and extension, development of new buildings and facilities, and construction of underground structures like subway tunnels in urban areas give rise to significance of site investigation at urban areas. However, ambient electric noises, traffic vibrations, embedded objects work as obstacles to high-quality and accuracy in site investigation at urban areas. In this paper, a new technique called the pseudo-DC resistivity survey (in brief, PDC-R) was proposed to minimize the adverse effect of ambient electrical noises in resistivity survey. PDC-R technique utilizes an AC current with frequency range of 0.1 to 1.0 Hz rather than DC current, which is used for conventional resistivity survey. The motivation of using low-frequency AC current is to avoid 60-Hz components or its multiples in the resistivity survey which ambient noises are mostly composed of. The implementation of PDC-R technique also included the parametric study on skin effect, frequency effect and current-level effect, which led to the determination of optimal values of frequency and current level for PDC-R survey. The reliability and feasibility of PDC-R technique was verified through field tests, accompanied by the comparison with DC resistivity survey and CapSASW tests.

Propellant Consumption Estimation of Reaction Control System During Flight of KSLV-II (한국형발사체 추력기 자세제어시스템 비행 중 추진제 소모량 추정식)

  • Kang, Shin-jae;Oh, Sang-gwan;Yoon, Won-jae;Min, Byeong-joo
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.48 no.7
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    • pp.529-536
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    • 2020
  • Reaction Control System of the third stage of the Korean Space Launch Vehicle II conducts roll control and 3 axis control throughout third stage engine start, satellite separation, and collision and contamination avoidance maneuver. Reaction control system consumes its propellant in each thruster operation. Hence, loading of proper amount of the propellant is important for mission success. It is needed to have a rough estimation method of propellant consumption during the flight. In this paper, we developed a energy equation using pressure and temperature data which are acquired in the on-board reaction control system. We constructed a test system which is similar with the on-board reaction control system to verify the energy equation. Test results using deionized water were compared with estimated propellant consumption. We also conducted an error analysis of the energy equation. We also presented the propellant consumption result of a system level operation test.

The Study on Design of Circuit Card Assembly on Servo Control Unit for Automated Resupply Vehicle K56 (K56 탄약운반장갑차용 서보제어기의 회로카드조립체 설계에 관한 연구)

  • Lee, Ju-Seung;Kim, Seong-Jin;Bae, Gong-Myeong;Kwon, Soon-Mo;Park, Hyean-Jo;Choi, Jun-Sok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.102-109
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    • 2019
  • This paper describes the design of the circuit card assembly to eliminate the communication error on a servo control unit installed in the automated resupply vehicle K56. K56 is a weapon system that automates the supply and loading of ammunition on the K-55A1 self-propelled artillery. As the core item responsible for ammunition movement control, the servo control unit is required to have good communication stability and reliability, but the conventional unit has recognized a problem that communication error intermittently occurs, resulting in an emergency stop phenomenon. We analyzed the communication signal of the servo control unit and identified the failure cause of the circuit card assembly to solve this problem. In addition, the signal interference in data/address line of the circuit card assembly was confirmed through analysis of the failure cause, and redesigned to avoid the interference, such as adjustment of the distance between communication lines and position change. Finally, the proposed cause analysis and redesign were verified through the component of servo control unit and attachment test on K56. We expected these study results to be used as reference for the design of other similar items.

Commuting Efficiency Comparison of Metropolitan Areas in South Korea: Application of Constrained Monte-Carlo Simulation to Avoid the MAUP (우리나라 대도시권 통근 효율성 비교: MAUP 회피를 위한 Constrained Monte-Carlo Simulation의 활용)

  • Hyunseong Yun;Seung-Nam Kim
    • Land and Housing Review
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    • v.15 no.2
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    • pp.73-87
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    • 2024
  • To evaluate the efficiency of commuting patterns, various commuting indicators such as excess commute and commuting potential utilized have been developed and used. It is crucial to calculate these indicators reasonably to reveal the differences in commuting patterns among metropolitan areas and to consider these in the process of formulating commuting policies. However, commuting indicators are generally calculated at the administrative district level, and thus, they are not free from the problem of the modifiable areal unit problem (MAUP). This issue can undermine the rationality of comparing commuting efficiency between metropolitan areas, making it necessary to handle the calculation of commuting indicators carefully. Therefore, this study utilises Monte Carlo Simulation to calculate optimal, actual, and maximum commuting distances, and thereby presents the excess commute and the commuting potential utilized. To apply Monte Carlo Simulation to the context of South Korea, a constrained Monte Carlo Simulation is conducted, where residential and workplace locations used in the simulation are selected based on the actual locations of buildings. The analysis is conducted on 13 metropolitan areas with established metropolitan plans using the 2016 Household Travel Survey data. The commuting indicators calculated through the simulation showed minimal differences compared to the results obtained through conventional methods. The comparison of commuting efficiency among metropolitan areas revealed that even if the degree of spafial balance between residential and workplace locations is similar, the actual commuting patterns can differ significantly. It is suggested that further research considering characteristics such as the area of each metropolitan region will be necessary in the future.

Screeening of Natural Plant Resources with Acetylcholine esterase inhibitory activity and Effect on Scopolamine-induced Memory Impairment (천연식물자원으로부터 Acetylcholine esterase 저해 활성 탐색 및 인지기능에 미치는 영향)

  • Choi, Jang Won;Won, Mu-Ho;Joo, Han-Seung
    • Journal of agriculture & life science
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    • v.45 no.6
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    • pp.213-226
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    • 2011
  • This study was performed to investigate the effect of essential oils and ethanolic extracts of approximately 650 plant species on acetylcholine esterase (AChE) enzyme activity using Ellman's colorimetric method in 96-well microplates. The results showed that the ethanolic extracts from twig of Sophora subprostrata, twig of Phellodendron amurense, seed of Corylopsis coreana, and essential oil (EO) from Citrus paradisi, Cupressus sempervirens, Ocimum basilicum, Pinus sylvestris and Rosmarinus officinalis inhibited more than 80% of AChE activity. Among these, EO from Pinus sylvestris, C. sempervirens and C paradisi exhibited higher values of AChE inhibitory activity, which were 75, 84 and 99% at a concentration of 50 ug/ml, respectively. Finally, EO from C paradisi (grapefruit, GEO) showed the highest inhibitory activity towards AChE, which showed 91% of inhibition at a concentration of 20 ug/ml. We also examined the anti-dementia effects of GEO in mouse by passive avoidance test and Morris water maze test. The model mouse (male, ICR) of dementia (negative control) was induced by administration of scopolamine (1 mg/kg body weight). The latency time of sample group administrated with GEO (100 mg/kg, p.o.) increased significantly as compared with negative control on passive avoidance test. There were significant recovery from the scopolamine-induced deficits on learning and memory in water maze test through daily administrations with GEO (100 mg/kg, p.o.). From these results, we conclude that GEO treatment might enhance the cognitive function, suggesting that the EO of C. paradis may be a potential candidate for improvement of perceptive ability and dementia.

The Character of Kim Chang Hyup(金昌協)'s Zhi-Jue(知覺) Theory Through Comparison With Zhu Xii(朱熹)'s (주희(朱熹) 지각론(知覺論)과의 비교를 통해 본 김창협 지각론(知覺論)의 특징)

  • Lee, Chang Gyu
    • The Journal of Korean Philosophical History
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    • no.52
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    • pp.311-340
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    • 2017
  • This research focuses on the theory of Zhi-jue(知覺) by Kim Chang-Hyup(金昌協) through comparison between Kim Chang-Hyup's and Zhu Xi(朱熹)'s. In the point of supervision, Zhu Xi considered that Zhi-jue is one of the conditions caused by supervision, one the other hand, it is the action that make possible supervision. Kim Chang-Hyup emphasize the concept of Zhi-jue itself, he considered that Zhi-jue is the action that make possible supervision, and separate Zhi-jue from Xing(性) or Qing(情). In this process, Zhi-jue became the subject itself about supervision, so the mix about relation between Zhi-jue and supervision is solved. But there is a problem about gap between Zhi-jue and the nature from separate between Zhi-jue and Xing. Kim Chang-Hyup intend to separate Zhi-jue and Qing as subject and object, so he considered that Xing is not a reason of Zhi-jue, but rules. It's not a answer about what is the reason of Zhi-jue. Yet Zhu Xi also considered that Xing is the rules of Zhu-jue, only in the case that Zhi-jue means the resulf of supervision, Zhi-jue is considered as the effect of Zhi(智). So the relation problem about Zhi-jue as a subject and the nature is brought up by Joseon scholar who attempted to arrange the concepts of neo-confucianism. Eventually, in case of the relation about Zhi-jue and Xing, King Chang-Hyup and Zhu Xi has a common point, only in case of the relation about Zhi-jue and supervision, Definding Zhi-jue as the subject of supervision is the character of Kim Chang-Hyup's theory of Zhi-jue.

An Empirical Study on the Effect of Respondent Bias in PSM : Case in Apartment Pricing (PSM 가격평가 주체에 따른 아파트 가격결정 효용성 실증연구)

  • Cho, Han-Jin;Kim, Jong-Lim
    • Land and Housing Review
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    • v.7 no.4
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    • pp.217-223
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    • 2016
  • PSM is widely used pricing tool in field by the reason of data collection convenience and analytical intuitiveness. However, In high involvement environment, strategic respondent bias influence in reducing the price. By using 3 empirical cases of LH apartment for sale, We found that latent consumers' recognition of the range of acceptable and the range of optimal price are lower than real estate agent representative respondents'. This phenomenon is considered loss aversion effect of prospect theory to reduce loss by reducing price, and more influenced in high involvement situation than latent consumer respondents'. Also we found PSM result using real estate representative data is more useful in real market than latent consumers data distorted by loss aversion effects. The meaning of this study is finding some limitation in PSM using consumer data generally used. In further study, development of PSM measurement tool to minimize the effect of strategic bias are need to be studied. Also some new approaches in reinterpretation of the range of acceptable price and the range of optimal price are need to be followed.