• Journal of Mushroom
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• v.16 no.4
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• pp.347-351
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• 2018

The aim of this study is to investigate the effect of Eleutherococcus senticosus (ES) on the laccase and cellulase activity of Ganoderma lucidum mycelia. Following the addition of ES, the laccase activity of Ganoderma mushroom mycelia was found to be 0.84-2.18 times, 0.61-2.37 times, and 0.78-2.17 times the activity of mycelia treated with sawdust in Yeongji-1 (Y1; ASI-7004), Yeongji-2 (Y2; ASI-7071), and nokgak (GN; ASI-7013), respectively, with the laccase activity of Y2 being the highest at 0.947 U/min. Using the Congo-red assay, a wider clear zone was formed because of the CMCase activity of mycelia treated with ES than that of mycelia treated with sawdust. Cellulase activity was found to be 1.84-2.24 times, 1.77-1.87 times, and 2.74-2.81 times that of mycelia treated with sawdust in Y1, Y2, and GN, respectively, with the cellulase activity of GN being the highest at 0.172 U/min. However, the addition of ES did not affect the growth of G. lucidum mycelia.

• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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• 2001.11a
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• pp.117-120
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• 2001

본 논문에서는 약한 키를 가지는 대화식 영지식 증명을 이용한 인증 프로토콜의 안전성을 강화하는 방법을 제시한다. 일반적으로 대화식 영지식 증명을 이용한 인증 프로토콜은 충분히 길고 랜덤한 비밀키를 가정하고 그 비밀키에 대한 영지식 증명을 수행하게 된다. 하지만 때에 따라서 충분히 길지 않거나 랜덤하지 않은 비밀키가 선택될 수 있다. 즉, 좋지 않은 난수 발생기를 써야 하는 경우, 또는 패스워드처럼 의도적으로 약한 키를 사용하는 경우가 생기며, 대화식 영지식 증명은 이에 적합하지 않다고 알려져 있다. 본 논문에서는 비밀 동전 던지기(Secret Coin Tossing)라는 개념을 제시해서, 일반적인 영지식 증명을 이용한 인증 프로토콜을 약한 키를 가지는 영지식 증명 기반 인증 프로토콜로 쉽게 변환할 수 있는 프레임웍을 제안한다. 또한, 이 프레임웍을 이용해서 설계된 인증 프로토콜이 ideal cipher model에서 안전함을 보인다.

• Journal of Mushroom
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• v.16 no.4
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• pp.318-323
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• 2018

This study investigated whether Ganoderma lucidum (Y2)-mediated fermentation of Artemisia capillaris extract (ACE) could synergistically enhance its antioxidant, anti-inflammatory, and tyrosinase-inhibiting activities. Both G. lucidum extract and fermented ACE exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging ability, but with poorer efficacy than ACE (even at a low ACE concentration). Viability of RAW264.7 macrophages was significantly reduced in the presence of ACE (150 mg/mL and above). However, this effect was greatly mitigated upon G. lucidum-mediated ACE fermentation. Additionally, relative to the same concentration ($25{\mu}g/mL$) of G. lucidum mycelial extract, ACE exhibited an improved ability to significantly inhibit RAW264.7 macrophage nitric oxide (NO) production. Finally, relative to the same concentration ($200{\mu}g/mL$) of a positive control (arbutin), fermented ACE exhibited an approximately 3.66 times higher capacity for tyrosinase inhibition. These results suggest that G. lucidum-fermented ACE possesses enhanced tyrosinase-inhibiting activity and may be of utility as a skin-lightening agent.

• Proceedings of the Korean Journal of Food and Nutrition Conference
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• 2004.07a
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• pp.53-53
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• 2004

버섯류는 항산화, 항암, 항변이원성, 항콜레스테롤성 효과 등의 여러 가지 생리활성 기능을 나타내기 때문에 암 및 성인병에 대한 예방 및 개선효과가 기대되는 좋은 소재라 할 수 있다. 그러므로 본 연구에서는 영지버섯의 생리 기능에 대한 활성을 탐색하고자 영지버섯을 에탄올로 추출하여 항산화효과와 항돌연변이 효과를 측정하였다. MDA에 대한 단백질의 보호효과를 알아본 결과 영지버섯추출물은 MDA의 교차 결합 형성을 31.68％저해하였고 처리농도가 증가할수록 저해율은 증가하였다. (중략)

• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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• 1992.11a
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• pp.165-179
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• 1992

영지식 대화증명은 인증자(prover)가 비밀정보를 노출시키지 않으면서, 검증자(verifier)와 대화를 통해서 이 비밀정보를 알고 있음을 검증자에게 증명하는 방법이다. 본 논문에서는 ElGamal 암호 알고리듬을 이용하여 메세지 전송과 개인 인중이 동시에 가능한 순방향 영지식 증명 프로토콜과 역방향 영지식 증명 프로토콜을 제안한다. 그리고 전송효율을 송신한 전비트와 정보비트와의 비로 정의하여 각각의 프로토콜의 전송효율을 계산한다.

• Korean Journal of Food Science and Technology
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• v.21 no.6
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• pp.890-894
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• 1989

The proximate composition, minerals, fatty acids, and amino acids in three types of Ganoderma lucidum produced from timber bed cultivation, pot cultivation, and antlered form from pot cultivation were determined. The results obtained art as follows. The contents of crude fibers carbohydrates, crude proteins, crude fats and crude ashes were 47.2-499%, 29.1-31.1%, 15.2-15.6%, 4.0-4.4% and 1.3-1.7% on dry basis, respectively. The content of K (2,742-4,843 ppm in dry basis) was the highest, followed by p, Mg, Ca and Na. The ratio of unsaturated fatty acid in the total lipid was 81.0-82.1%. The major fatty acids were oleic acid and linoleic acid. The contents of histidine (9.47-13.06 mg/g on dry basis) and methionine (0.20-0.44mg/g in dry basis) were the highest and the lowest in the total amino acids, respectively.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.1
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• pp.148-153
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• 1997

The immunomodulating effects of polysaccharide extracted from Ganoderma lucidum(PSG) on macrophage were evaluated using murine macrophage cell line ATCC TIB 71 cells or peritoneal exudate cells of BALB/c mice. The cell were incubated with various content of PSG for 24 hours at 0.5% $CO_2$ incubator under varying experimental conditions. PSG stimulated the non-specific activites of macrophage such as mitotic activity and expression of surface interleukin-2 receptors by dose-dependent pattern with statistic significance(p<0.001): however, PSG had little immunoregulatory effects on cytokines derived from peritoneal macrophages of BALB/c mice. There were no significant changes in the se-cretion of interleukin-6, interleukin-6, or tumor necrosis factors(Tn) of PSG treated cells compared to the control group. But PSG increased secretion of cytokines(IL-1 and TNF) when the cells were primed and trigged with BCG and IFN-${\gamma}$.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.4
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• pp.357-364
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• 2017

The aim of this study is to investigate the effect of Hovenia dulcis (oriental raisin tree) extract on ganodermanondiol (GN) contents in Ganoderma lucidum (G. lucidum) mycelia. GN has a triterpenoid structure and is one of the major active components of G. lucidum. Furthermore, we previously proved its inhibitory effects on tyrosinase activity and melanin biosynthesis in B16F10 melanoma cells. In this study, we observed significantly increased GN contents in G. lucidum mycelial extracts supplemented with 15% (v/v) oriental raisin tree extract (ORTE) by HPLC analysis. In addition, melanogenesis was significantly inhibited by G. lucidum extract supplemented with 15% ORTE when compared to G. lucidum extract without ORTE supplementation. Furthermore, mycelial growth of G. lucidum was increased by ORTE supplementation in both solid and liquid cultivation. These results suggest that the oriental raisin tree is useful as natural ingredient for increasing GN biosynthesis as well as whitening effect of G. lucidum.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.12 no.1
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• pp.33-42
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• 2002

We present a systematic way to armor a zero-knowledge interactive proof based identification scheme that has badly chosen keys. Keys are sometimes mistakenly chosen to be weak(neither random nor long), and a weak key is often preferred to a strong key so that it might be easy for human to remember. Weak keys severely degrade the security of ZKIP based identification schemes. We show using off-line guessing attack how the weak key threats the security of ZlKIP based identification schemes. For the proper usage of ZKIP, we introduce a specialized form of ZKIP, which has a secret coin-tossing stage. Using the secret coin tossing, a secure framework is proposed for ZKIP based identification schemes with weak key in the ideal cipher model. The framework is very useful in password based authentication and key exchange protocol

• Korean Journal of Food Science and Technology
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• v.29 no.1
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• pp.156-160
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• 1997

The monoamine oxidase (MAO, EC 1.4.3.4) plays a central role in the metabolism of many amines including the neurotransmitter monoamines. MAO is a flavoprotein found exclusively in the mitochondrial outer membrane, occuring in the MAO-A and MAO-B subtypes. MAO-A deaminates serotonin and noradrenaline much better than phenethylamine (PEA) or benzylamine (BA), and is preferentially inhibited by clorgyline, whereas MAO-B prefers PEA and BA as substrates and is preferentially inhibited by deprenyl. MAO inhibitors were among the first drugs used in the treatment of depression, and it is known to be the inhibition of MAO-A which is important for the antidepressant effect of MAO inhibitors. For the purpose of evaluating MAO inhibitory activities from natural resources, three kinds of edible mushrooms were screened by tracing the inhibitory activities against rat brain mitochondrial MAO-A, utilizing serotonin as a substrate and rat liver mitochondrial MAO-B utilizing benzylamine as a substrate. Among the tested mushrooms, Ganoderma lucidium and Lentinus edodes showed the weak inhibitory activities against MAO-B.