• Title/Summary/Keyword: 약 치료

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The Current Pathobiology and Chemotherapy of Clonorchiasis (간흡충증과 최신화학요법)

  • 임한종
    • Parasites, Hosts and Diseases
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    • v.24 no.1
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    • pp.3-141
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    • 1986
  • 간흡충은 우리나라를 비롯하여 중국, 대만, 일본 및 월남등지에 널리 분포되어 있으며 1947년에 Stoll씨의 통계에 의하면 세계적으로 1,900만명이 넘는 감염자가 있다고 하였다. 현재 우리나라에서만 약 200만명의 간흡충 감염자가 있을 것으로 추산되고 있다. 간흡충은 McConnell이 1874년에 인도의 Calcutta에서 한 중국인의 간담도에서 본충을 처음 발견한 것이다. 이것을 Cobbold(1875)가 Distoma sinense라고 명명하였다가 후에 Looss (1907)가 Clonorchis sinensis라고 하였다. Kobayashi (1910)는 담수어가 간흡충감염의 중간숙주로 작용한다는 것을 처음으로 발견하였고 Muto (1918)에 의하여 왜우렁이가 제1중간숙주임을 발견함으로서 간흉충의 생활사가 확실해 졌다. Faust 및 Khaw (1927)에 의하여 중국에서 간흡충의 생물학 및 역학에 관한 광범한 연구업적이 발표된 이래 일본, 한국, 중국등 여러곳에서 많은 사람들에 의하여 연구되어 왔다. 그러나 적절한 치료방법이 없었고 또 민물고기를 생식하는 식습관과 위생시설의 미비등 여러가지 요인때문에 예방이 어려움에 직면하였다. 최근 다행히 새로이 개 발된 praziquantel이 간흡충중에 대하여 우수한 치료효과를 나타내고 집단치료에도 적합하다는 것이 증명됨으로서 간흡충증 예방과 관리에 큰 서광이 보이게 되었다. 따라서 간흉충증의 발생과 임상적 병증의 중요성을 좀 더 이해하기 위하여 간흡충체의 미세구조, 병인, 역학, 임상증상등 최근 알려진 새로운 지견과 우리나라에 있어서 간흡충증의 분포 및 유행지 형성 상황을 수학적으로 역학적 분석을 시도하였다. 그리고 과거 간흡충중의 화학치료에 관한 연구성적을 종합하여 화학요법제의 특성 빚 치료 적용여부에 대하여 논하였고 각약제의 시험관내 및 실험동물에 있어서의 살충효과와 임상시험에 있어서의 치료효과 및 부작용에 대하여 기술하였다. 그리고 새로 개발된 praziquantel의 간흡충에 대한 작용기전에 대하여도 논하였다. (중략)

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Treatment of The Shoulder Impingement Syndrome (견관절 충돌증후군의 치료)

  • Choi, Byoung-Ok;Yu, Byoung-Kyu
    • Journal of Korean Physical Therapy Science
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    • v.3 no.4
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    • pp.121-138
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    • 1996
  • Impingement syndrome is mechanical impingement between the greater tubercle of the humerus and the under surface of the coracoacromial arch, is a common source of shoulder pain in the athletes as well as non-athletes. Several factors contribute to shoulder impingement syndrome, including rotator cuff weakness, capsular tightness, poor scapulohumeral rhythm, and muscle imbalance of the scapular upward rotation force couple. The purpose of this article is to review current concepts of anatomy and biomechanics and the underlying pathomechanics as it relates to evaluation and treatment of shoulder impingement syndrome.

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A Case of Globus Hystericus caused by psychological, digestive disorder (정신과적, 소화기성 원인으로 유발된 Globus Hystericus 치험 1례)

  • Lee, Hyun-Woo;Chang, You-Jin;Hong, Seung-Ug
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.26 no.2
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    • pp.88-97
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    • 2013
  • Objectives : 본 연구를 통해 정신과적, 소화기성으로 유발된 히스테리성 구를 반하백출천마탕과 자음건비탕으로 치료한 1례를 보고하려 한다. Methods : 오심, 불면, 이명, 소화불량, 초조, 두통, 매핵기를 주소로 하는 23세 여성 환자를 대상으로 약 4개월 동안 침구, 반하백출천마탕과 자음건비탕으로 치료하였다. Results & Conclusions : 4개월 동안의 치료 후, 히스테리성 구와 다른 증상들이 소실되었다. 이 논문에서는, 소화기계 장애와 정신 질환 치료를 위해 오랫동안 사용되어온 반하백출천마탕과 자음건비탕을 히스테리성 구 치료에 이용하였다. 결론적으로, 본 연구는 히스테리성 구와 소화기계 장애가 밀접한 관련이 있음과 히스테리성 구에 대한 한의학적 치료의 중요성을 제시하였다.

Myofascial Pain, and the Spraying and Stretching Technique (근막동통과 분사신장요법)

  • Kim, Byung-Gook;Lim, Young-Gwan
    • Journal of Oral Medicine and Pain
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    • v.25 no.3
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    • pp.325-329
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    • 2000
  • 근막동통은 발통점과 중추흥분효과가 나타나는 국소적 근육성 동통이다. 발통점은 근육의 일부나 건 부착점에 나타나는 부위로서 단단한 띠로서 느껴지고 촉진시 통증을 유발한다. 통증은 관련된 발통점의 위치에 따라 연관된 부위에 나타난다. 이러한 근막 발통점에 따른 증상은 약한 기능이상부터 일상생활이 어렵게 되는 정도의 심한 통증까지 다양하다. 이의 발생에는 국소적 근육이상, 심부 동통, 심리적 스트레스의 증가, 수면장애와 전신적인 요인들도 관여한다. 일반적으로 치료는 보존적인 처치로써, fluoro-methane 같은 vapocoolant spray를 사용하는 사용하여 분사신장하는 방법이 있으며, 국소적인 주사, 마사지, 초음파, 온열요법등이 있다. 여러 환자에서 근막동통을 가지는 환자에 분사신장요법을 시행한 결과 대부분 환자에서 증상의 개선을 보였다. 근막동통의 치료시 분사신장요법은 매우 보존적인 처치로 임상가의 적용과 접근이 쉬우며, 환자로 하여금 치료에 따른 불안감을 줄이면서 만족을 느낄 수 있는 치료로 사료된다. 그러나 만성 환자의 경우 분사신장요법의 치료결과에 대한 만족도가 높지 않았다. 분사신장 용법은 근막동통을 가진 환자 모두에서 효과적이지는 않으나 치료의 도입으로, 근막동통을 진단시에 일차적으로 사용할 수 있는 안정한 보존적인 용법으로 사료된다.

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CARIES TREATMENT OF A MIDAZOLAM-PREMEDICATED PATIENT WITH DEVELOPMENTAL DISORDERS : A CASE REPORT (미다졸람 경구 전투약을 이용한 발달장애 환아의 전신마취하 우식치료 증례보고)

  • Kim, Hyo-Eun;Shin, Teo-Jeon;Kim, Young-Jae;Kim, Jung-Wook;Jang, Ki-Taeg;Lee, Sang-Hoon;Kim, Chong-Chul;Hyun, Hong-Keun
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.9 no.1
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    • pp.46-50
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    • 2013
  • Developmental disorders are a group of psychiatric conditions originating in childhood that involve serious impairments in different areas. These disorders comprise language disorders, learning disorders, motor disorders and autism spectrum disorders. Midazolam is a short-acting drug in the benzodiazepine class developed by Hoffmann-La Roche in the 1970s. The drug is used for treatment of acute seizures, moderate to severe insomnia, and for inducing sedation and amnesia before medical procedures. It possesses profoundly potent anxiolytic, amnestic, hypnotic, anticonvulsant, skeletal muscle relaxant, and sedative properties. The anterograde amnesia property of midazolam is useful for premedication before surgery to inhibit unpleasant memories. This article presents a case report including caries treatment of a 8-year-old male patient with developmental disorders using oral midazolam premedication as an alternative method of behavior management prior to general anesthesia.

ERUPTION GUIDANCE OF IMPACTED MANDIBULAR FIRST MOLAR (매복된 하악 제1대구치의 맹출 유도)

  • Lee, Doo-Young;Song, Je-Seon;Lee, Jae-Ho;Choi, Byung-Jai;Kim, Seong-Oh
    • Journal of the korean academy of Pediatric Dentistry
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    • v.37 no.2
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    • pp.226-232
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    • 2010
  • Incidence of tooth impaction varies from 5.6 to 18.8% of the population. Failure of eruption of the first and second permanent molars is rare; the prevalence in the normal population is 0.01% in case of the first permanent molar, and 0.06% in case of the second permanent molar. Permanent molars are particularly important for providing sufficient occlusal support and co-ordinating facial growth. Failure of eruption of permanent molars may result in various complications such as decrease in vertical dimension, posterior open bite, extrusion of antagonistic teeth, resorption and inclination of adjacent teeth, formation of cyst and so on. Treatment options of impacted teeth are periodic observation, surgical exposure, surgical exposure with subluxation, orthodontic relocation, and surgical extraction before prosthetic treatment. Early diagnosis and treatment are important, because delayed treatment induces various problems such as decreased spontaneous eruptive force, decreased successful percentage, increased treatment period, increased various complications. Prevalence of the failure of mandibular first molars is rare but eruptive guidance before extraction of impacted teeth is necessary due to importance of permanent molars. We reported two cases of surgical exposure of impacted mandibular first molar. In these cases, we could observe different result of the impacted mandibular first molar after surgical exposure.

The consideration about the shielding effect of LEDITE (LEDITE를 이용한 방사선 차폐시설에 관한 고찰)

  • Min Je-soon;Lee Je-hee;Park heung-deuk
    • The Journal of Korean Society for Radiation Therapy
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    • v.15 no.1
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    • pp.11-18
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    • 2003
  • The concrete is usually used to build a radiation therapy facility and the enough concrete thickness for high energy x-ray beam is about 1 meter. But if the space is not enough to build a radiation therapy facility with concrete, the substitute for concrete is needed, and the Ledite can be a good substitute for concrete. In this study, we compared the Ledite with the concrete. The comparing list are the needed shielding thickness, the period of construction and the cost.

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Experimental Research for Traction force Sensor Development on Drawing Exercise Medical Instrument (재활 및 교정을 위한 견인운동치료기의 견인측정센서 개발에 관한 실험적 연구)

  • Lee, Sang-sik;Park, Won-yeop;Lee, Choong-ho
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.2 no.2
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    • pp.3-8
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    • 2009
  • The traction system has been mainly used for rehabilitation and correction of patients with spine or gait diseases in orthopedics or at home. Some problems could occur in human body when patients forced their training using the traction system. So it needs to measure a traction force and control the training time. However, most of products on market have no sensor measuring traction force. Thus we designed and made a sensor detecting traction force using strain gauge, amplifier for transition to output signal and experiment devices for performance test. We carried out experiment of a sensor detecting a traction force and measured electric responses of it with respect to traction loads. Maximum error was within about 1% for experiments in static condition and the average error was about 0.7% for experiments in dynamic condition. We concluded that it is possible to use the developed sensor for measurement of traction force since the maximum output variation of a sensor detecting a traction force was about 0.3% in $0^{\circ}C-60^{\circ}C$ temperature condition.

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Use of Single-System Design to Evaluate the Effectiveness of Cognitive Behavioral Therapy of Depression (임상실천 평가를 위한 단일체계설계의 적용 -우울증 감소를 위한 인지행동치료에 대한 평가를 중심으로-)

  • Kim, Yong-Seok;Shon, Dong-Gyun
    • Korean Journal of Social Welfare
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    • v.60 no.2
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    • pp.175-209
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    • 2008
  • The purpose of this study, which has its focus on the utilization of single-system design for practice evaluation, is to evaluate the effectiveness of cognitive behavioral therapy of depression by using a AB design. 3 inpatients in a local hospital with a diagnosis of major depressive disorder agreed to participate in this study. The AB design includes a 2weeks of the baseline phase and 3 weeks of the intervention phase. More than one outcome measures were used in order to validate the results of the measurement. Data were analyzed statistically as well as visually. Tools such as trend line and trend index were used to improve the accuracy of the visual analysis and the 3 standard deviation approach was used for statistical significance test. The results showed that all clients improved. This study lists some advantages of using single-system design for evaluating clinical practice: monitoring, encouraging clients' active role in social work process, and easy data analysis.

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Useful evaluation of 3D target location correction by using Xsight spine tracking system in CyberKnife (사이버나이프에서 Xsight spine tracking system을 이용한 3D 표적위치보정의 유용성 평가)

  • Jeong, Young-Joon;Kim, Sang-Hyun
    • Journal of Digital Convergence
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    • v.13 no.1
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    • pp.331-339
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    • 2015
  • The purpose of this study is to evaluate utility of rotating adjustment using Xsight spine tracking system in 3D DOF location adjusting method, to minimize error between 6D DOF and 3D DOF in fiducial tracking system. In this study, the result of 6D DOF target location error is $0.124{\pm}0.058mm$, using fiducial inside tumor 3D DOF $0.673{\pm}0.142mm$, outside tumor $1.126{\pm}0.253mm$, apply with Xsight spine tracking system 3D DOF $0.542{\pm}0.103mm$. As the experiment shows, it was demonstrated that rotating adjustment through Xsight spine tracking system is valuable in case of treatment in 3D DOF location error that makes increasing accuracy and dose distribution each approximately 48% and 3%. In accordance with result of this study is useful rotation.