• Annual Conference of KIPS
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• 2019.05a
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• pp.631-634
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• 2019

단백질의 구조적 동등성을 평가를 위한 형태 기반의 기술자에 대한 연구는 제한적으로 이루어지고 있으며 대부분 지역적 특성 값으로 표현된 지역적 접근 방법이 다수를 이루고 있다. 지역적 특성과 전역적 특성을 포함하는 형태기술자의 경우 각 특성들이 동등한 중요도로 결합되어 있다. 본 연구에서는 선형 회귀분석을 적용하여 각 특성에 대한 중요도를 최적화하여 형태기술자를 재정의 하였다. 최적화된 형태기술자를 단백질의약품인 인슐린 모델에 적용하여 구조적 동등성을 평가할 수 있는 방법론을 제시하였다. 최적화된 형태기술자는 동일한 그룹에 속한 인간 인슐린 단백질 모델과 지역적으로 다른 구조를 가지는 인슐린 아날로그 그룹을 명확히 구분할 수 있음을 확인하였고 이러한 성능은 이전 연구의 형태기술자와 3D 저니크 기술자보다 더 좋은 성능을 보였다. 또한 제안한 방법은 고해상도 단백질 3차 구조 정보를 활용하여 유사성을 판별한 RMSD 방법과 유사하게 서로 다른 표면 구조를 가지는 단백질을 구별할 수 있음을 확인하였다. 이러한 결과로부터 본 연구에서 제시하는 형태기술자 및 최적화된 동등성 평가 함수는 SAXS 분석과 같이 저해상도 단백질 표면 모델을 확보할 수 있는 분석에 적용하여 단백질의 구조적 동등성을 판별할 수 있는 기반을 제공할 수 있을 것으로 판단된다.

• The Korean Journal of Financial Management
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• v.21 no.1
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• pp.149-181
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• 2004

In this study we perform empirical tests using KOSPI return to investigate the existence of nonlinear characteristics in the generating process of stock returns. There are three categories in empirical tests; the test of nonlinear dependence, nonlinear stochastic process and nonlinear deterministic chaos. According to the analysis of nonlinearity, stock returns are not normally distributed but leptokurtic, and appear to have nonlinear dependence. And it's decided that the nonlinear structure of stock returns can not be completely explained using nonlinear stochastic models of ARCH-type. Nonlinear deterministic chaos system is the feedback system, which the past incidents influence the present, and it is the fractal structure with self-similarity and has the sensitive dependence on initial conditions. To summarize the results of chaos analysis for KOSPI return, it is the persistent time series, which is not IID and has long memory, takes biased random walk, and is estimated to be fractal distribution. Also correlation dimension, as the approximation of fractal dimension, converged stably within 3 and 4, and maximum Lyapunov exponent has positive value. This suggests that chaotic attractor and the sensitive dependence on initial conditions exist in stock returns. These results fit into the characteristics of chaos system. Therefore it's decided that the generating process of stock returns has nonlinear deterministic structure and follow chaotic process.

• The Transactions of the Korea Information Processing Society
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• v.6 no.11
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• pp.2981-2988
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• 1999

A deductive database consists of facts being the extensional database and rules being the intensional database. Because of the difficulty of evaluating rules, many parallel evaluation algorithms for rules have been presented. But we have not gotten an acceptable result. This paper proposes a new methodology to evaluate proof-theoretic meaning of the linear recursion rule which contains transitive dependency by using a shared-nothing parallel architecture. As first, we prove that there exists the equivalent expression for a linear recursion rule, design the algorithm for evaluating the linear recursion rule based on the equivalent expression, and finally analyse performance of the proposed algorithm.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.20 no.5
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• pp.581-592
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• 2007

This paper deals with the elastica of deflected cantilever column with the constant volume. The columns are subjected to combined loads consisted of an axial compressive load and a couple moment at the free end. Differential equations governing the elastica of such column are derived, in which both the effects of taper type and shear deformation are included. Three kinds of taper types are considered: linear, parabolic and sinusoidal tapers. Differential equations are solved numerically to obtain the elastica of objective columns. The effects of various system parameters on the elastica are investigated extensively. Experimental studies were carried out in order to verify the theoretical results of non-linear behavior of the elasticas.

• Progress in Medical Physics
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• v.2 no.1
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• pp.29-35
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• 1991

For accureate treatment planning, new models of dose calculations are being developed which require the knowledge of the energy spectra and angular distributions of the X-rays incident on the surface of the material. In this present study, we applied the Monte Carlo methods to the systematic analysis of the spectra distribution of X-ray beams produced by medical linear accelerator. As expected, the spectra become softer as the distance is farther from the central axis. also, its influenced by the geometrical dffect of head system.

• The Journal of the Acoustical Society of Korea
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• v.20 no.8
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• pp.44-57
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• 2001

This paper analyses the performance of FFTSA (Fast Fourier Transform Synthetic Aperture) in the effects of temporal coherence and oscillatory towed course, which is one of the techniques for passive synthetic aperture SONAR process using linearly distributed towed array. Also this paper proposes the FFTSA technique using towed array having conformal shape to alleviate the performance degradation for estimating the incident angle under inconsistent under water environments. And this paper analyses the performance of the proposed FFTSA technique making use of conformal structure throughout exhaustive computer simulations.

• Journal of the Korean Institute of Telematics and Electronics
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• v.13 no.3
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• pp.22-27
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• 1976

For linear IC design, one has to know the epi thickness, resistivity, and structure of buried island inserted between epi and substrate because the mask structure can only be changed for linear IC consisted of various type of transistors to be made for desired specific function. The interrelation of IC operational and saturation voltages with epi resistivity, theckness and divice structure are studied and presented in graphic forms so that IC design engineers can utilize them.

• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.6
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• pp.177-184
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• 2021

In recent years, large-scale earthquake activity has occurred in Korea, and thus public interest in earthquakes is increasing. Accordingly, the importance of seismic performance management of structures is emerging. In particular, the collapse of a bridge, one of main road facilities, directly leads to many casualties. Therefore, engineers need to evaluate the seismic fragility of the bridge and prepare for the earthquake event. The service life of these bridges has been over 30 years, which requires a study on the aging effect on bridges. In this study, seismic analysis of the target RC slab bridge was performed considering the aging effects of each component of the bridge. Components of the bridge included pier and bearing, which dominate the seismic response of the bridge. The seismic performance of the bridge was evaluated using nonlinear static and dynamic analyses. In addition, the limit state and dynamic response of each component were used to evaluate the seismic fragility according to the aging of each component.

• Applied Chemistry for Engineering
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• v.10 no.7
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• pp.990-995
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• 1999

To determine the effect of chemical structure of linear amine curing agents on thermal and mechanical properties, standard epoxy resin DGEBA was cured with ethylene diamine(EDA) and hexamethylene diamine(HMDA) in a stoichiometrically equivalent ratio. From this work, the effect of linear amine curing agents on the thermal and mechanical properties is significantly influenced by the chemical structure or chain length of curing agents. In contrast, the results show that the DGEBA/EDA system having the two carbons had higher values in the thermal stability, maximum conversion of epoxide, density, glass transition temperature, tensile modulus, flexural strength, and flexural modulus than the DGEBA/HMDA system having the six carbons, whereas the DGEBA/EDA cure system had relatively low values in the shrinkage(%), thermal expansion coefficient, tensile strength, and had similar values in the maximum exothermic temperature, and conversion of epoxide compared to the DGEBA/HMDA cure system. This findings indicate that packing ability in the HMDA structure affects the thermal and mechanical properties.

• Proceedings of the Korea Water Resources Association Conference
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• 2017.05a
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• pp.370-370
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• 2017

최근 기후변화와 이상기후의 영향으로 인하여 홍수재해의 시 공간적 패턴은 보다 복잡해지고, 예측이 어려워지고 있다. 이러한 기상이변에 따른 홍수피해를 예방하기 위한 비구조적 대책으로 홍수위험등급 및 범람범위 등의 정보를 포함하고 있는 홍수위험지도의 작성이 필요하다. 실제로 고정밀도 홍수위험지도를 작성하기 위해서는 지형, 지질, 기상 등의 디지털 정보 및 사회 경제와 관련된 다양한 DB를 필요로 하며, 강우-유출-범람해석 모델링을 통해 범람면적 및 침수깊이 등의 정보를 획득하게 된다. 하지만 일부지역, 특히 개발도상국에서는 이러한 계측 홍수 데이터가 부족하거나 획득할 수가 없어 홍수위험지도 제작이 불가능하거나 그 정확도가 매우 낮은 실정이다. 따라서 본 연구에서는 ASTER 또는 SRTM과 같은 범용 DEM 등 지형자료만을 기반으로 한 선형이진분류법(Liner binary classifiers)과 ROC분석(Receiver Operation Characteristics)을 이용하여 미계측 유역 (DB부재 또는 부족으로 강우-유출-범람해석 모델링이 불가능한 북한지역)의 홍수위험지역을 탐지하고, 적용성을 평가하고자 한다. 5개의 단일 지형학적 지수와 6개의 복합 지형학적 지수를 이용하여 Area Under the Curve (AUC)를 계산하고, Sensitivity (민감도)와 Specificity (특이도)가 가장 높은 지수를 선별하여 홍수위험지도를 작성하고, 실제 홍수범람 영상(2007년 북한 함경남도지역 용흥강 홍수)과 비교 분석하였다. 본 연구에서 제시하는 선형이진분류법과 ROC분석 방법은 홍수범람해석을 위한 다양한 기초정보를 필요로 하지 않고, 지형정보만을 사용하기 때문에 관측 데이터가 없거나 부족한 지역에 대해서 우선적으로 홍수위험지역을 탐지하고, 선별하는데 유용할 것으로 판단된다.