• Title/Summary/Keyword: 비무기

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Liquid-Liquid Extraction for Recovery of Paclitaxel from Plant Cell Cultures by Adding Inorganic Salts (식물세포배양으로부터 파클리탁셀 회수를 위한 무기염이 첨가된 액-액 추출)

  • Ha, Geon-Soo;Kim, Jin-Hyun
    • Korean Chemical Engineering Research
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    • v.54 no.1
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    • pp.135-139
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    • 2016
  • We developed a liquid-liquid extraction method using an inorganic salt to dramatically improve the recovery efficiency of the anticancer agent paclitaxel from plant cell cultures. As a result of liquid-liquid extraction using a diverse types of inorganic salt (NaCl, KCl, $K_2HPO_4$, $NaH_2PO_4$, $NaH_2PO_4{\cdot}2H_2O$), NaCl gave the highest yield (~96%) and lowest partition coefficient (0.053) of paclitaxel. The optimal NaCl/solvent ratio, methylene chloride/MeOH ratio, and pure paclitaxel content for liquid-liquid extraction using NaCl were 1% (w/v), 26% (v/v), and 0.066% (w/v), respectively. Under the optimal conditions developed in the present method, most of the paclitaxel (~96%) was recovered from biomass by a single extraction step. In addition, this method facilitated 3-fold higher recovery efficiency of paclitaxel in a shorter extraction number than the conventional liquid-liquid extraction method.

Abolition of the Japan's 3 Principles on Arms Exports and Defense Industry (일본의 무기수출 3원칙 폐지와 방위산업)

  • Kim, Jong Ryul
    • Convergence Security Journal
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    • v.14 no.6_1
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    • pp.23-32
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    • 2014
  • Japan has abolished the 3 Principles on Arms Exports and announced the new 3 Principles on Transfer of Defense Equipment and Technology. This article investigates the backgrounds of the abolition of the old regulation on banning arms exports. Japan government repealed 3 principles on arms exports to develop military industry and they insist that they pursue their national strategy called "Proactive Contribution to Peace." The future changes in defense industry due to the new principles are examined with the analysis of the defense industry indicators. The home production of the arms could be continued. However the international cooperation for the co-development and co-production of the weapon systems would be increased with not only the US but also the various countries. At the same time the efforts to export arms overseas are anticipated to be enhanced by the Japanese government and defense companies.

Studies on the Changes in Activities of ALPase, ACPase, ATPase and Synthesis of Volutin Granules upon Phosphate Concentration in Saccharomyces uvarum (Saccharomyces uvarum의 인삼염첨가배양에 따른 ALPase, ACPase, ATPase 활성도와 volutin과립의 함량변화)

  • 이기성;최영길
    • Korean Journal of Microbiology
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    • v.23 no.2
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    • pp.84-89
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    • 1985
  • The effect of exogenous phosphate supply on the regulation of phosphate metabolism was investegated during catabolic repression and catabolic derepression in yeast (Saccharomyces uvarum). As the results, when sugar was supplimented in cells cultivated under phosphate free, the growith rate was low but it was capable of cell division. Polyphosphate "B" was accumulated highly in proportion to amount of phosphate added to the medium. Without regard to phosphate supply of the medium, the total amount of polyphospgate was almost similar, although each polyphosphate was turned over. Activities of all phosphatases remained continuousoy high in the cells cultivated in the phosphate free medium. Especially under catabolic repression, the function of polyphosphate system was shown to compensate the ATP/ADP system as phosphate donor, energy source and regulator.

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Non-Volatile Organic Acids, Mineral, Fatty Acids and Fiber Compositions in Dolsan Leaf Mustard (Brassica juncea) (돌산 갓의 비휘발성 유기산, 무기질, 지방산 및 섬유소 조성)

  • 박석규;조영숙;박정로;전순실;문주석
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.1
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    • pp.53-57
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    • 1993
  • The compositions of non-volatile organic acids, mineral, fiber and fatty acids of leaf mustard were investigated. Non-volatile organic acid contents were higher in leaf than in leaf stalk. Of non-volatile organic acids assayed malic acid was the most abundant in both leaf (79.1 mg%) and leaf stalk (46.4mg%), followed by L-ascorbic, oxalic, citric and succinic acids. Mineral contents were also higher in leaf than in leaf stalk. Both leaf and leaf stalk contained calcium most, followed by magnesium, sodium, iron, zinc and copper. It has also been found that leaf mustard contains more iron than any other Cruciferous vegetables reported. The major fatty acid of total lipid was $\alpha$-linolenir acid (63.2% in leaf, 55.3% in leaf stalk). The ratios of polyun-saturated fatty acids to saturated fatty acids (P/S ratio) were 4.1 in leaf and 2.9 in leaf stalk. The content of pectic substances, in terms of alcohol-insoluble solid, of leaf was 9.4% which was 1.4-fold higher than that of leaf stalk. Of pectic substances, hot soluble pectins (HWSP) were present most and followed by sodium hexametaphosphate soluble (HXSP) and HCI soluble pectins (HSP). Total dietary fiber content of mustard leaf was 2.68% and in general, higher content of total dietary fiber than leaf had. Neutral detergent fiber content was higher than acid detergent fiber, and cellulose was higher than hemicellulose by 2.1-fold in leaf stalk.

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System Safety Role on FFRR (초도비행 안전점검과 시스템 안전)

  • 조건현
    • Journal of the KSME
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    • v.34 no.1
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    • pp.33-43
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    • 1994
  • 오늘날과 같이 시스템의 복잡화에 따른 고가의 시스템 구입비, 크기 및 중량의 허용한계 등과 같은 여러 제한요인 때문에 고도의 신뢰성 있는 무기체계 개발을 위해서는 무기체계 개발과정의 전 순기 동안에 시스템 안전(system safety)분야의 적용이 불가피하게 되었다. 시스템 안전에 관한 연구는 매년 증가하는 사고로부터 발생하는 엄청난 손실을 줄여보자는 필요하에 1960년 경부터 미국의 군대에서 시작되었다. 1969년 7월 미국 군사표준서MIL-STD-882(시스템 및 관련 부시스템에 대한 시스템 안전 프로그램 요구조건)가 제정된 이후 요즈음 미군의 방산물자 조달 및 획득시 시스템 안전분야 적용이 의무화되어있다. 시스템 안전분야는 개발중인 시스템의 설계, 개발, 운용과 관련된 여러 분야, 즉 품질보증, 인간공학, 시스템공학, 형상관리분야 등과 상호 밀접하게 연관되어 있으므로 이 분야에 대한 상호 이해와 끊임없는 정보교환이 요청되고 있다. 시스템 구성분야별, 무기체계 개발단계별로 조직적으로 분석된 시스템 안전결과를 토대로 프로 젝트 관리자(PM)는 개발중인 무기체계 시스템에 내재된 시스템 위험을 어느 수준까지 수용할 수 있을 것인가에 대한 현명한 판단을 내릴 수가 있게 되는데 항공기개발 프로그램의 경우 시스템 안전의 궁극적인 목표는 성공적인 초도 비행이라고 할 수 있다.

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핵, 생ㆍ화학무기 및 미사일의 확산 제재: 최근 미국내 관련 법규 개요

  • Kim, Hyeon-Cheol
    • Science & Technology Policy
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    • v.13 no.4 s.142
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    • pp.90-101
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    • 2003
  • 대량살상무기의 확산을 근본적으로 차단하기 위한 경제 제재의 활용은 1990년대에 들어서 새로운 차원으로 전개됨. 이전시기까지 제정된 법규들은 특정한 핵확산 활동에 관여한 국가들에 대한 외국원조의 중단을 요구하였으며, 해당 국가들이 관련 조약 및 국제협약상의 목표를 준수하게끔 하나의 가능한 메커니즘으로서 제재 방안들을 규정함. 1990년에 들어서서 미 의회는 미사일 확산에 관련되어 무역제재를 위한 명확한 지침을 입법화함. 1990년에 들어서 무기수출통제법(Arms Export Control Act)과 1979년 수출관리법 (Export Adminstration Act of 1979)에 미사일기술통제레짐의 부속서(MTCR Annex)에 등재된 품목이나 기술을 거래하는데 관여한 미국 시민 또는 외국인에 대해 미 대통령이 규제를 부과한다는 점이 필수사항으로 첨가됨. 이어서 미 의회는 광범위한 형태의 법률을 통해 생ㆍ화학무기 및 핵무기의 확산에 기여하는 국가들에 대해 경제제재를 가할 것을 입법화함. 본 보고서에서는 미국내 비확산 규정을 위반한 국가, 기업 또는 개인들에 대해 일종의 경제제재를 부과하는 것을 요구하거나 승인하는 법규들을 간략히 서술하고 있음. 다음에 열거하는 각각의 규정에는 제재 부과의 이유, 제재 기간에 관련된 정보를 포함하여, 미 대통령이 제재 부과를 연기, 중단 및 포기할 수 있는 권한의 구체적 내용들을 서술함.

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Mineral Contents of Underground Vegetables Produced in Different Regions of Korea (국내산 식용 지하 부위 채소의 생산지역에 따른 무기질 성분 함량에 관한 연구)

  • 장경미;이미순
    • Korean journal of food and cookery science
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    • v.16 no.5
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    • pp.425-430
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    • 2000
  • This study was carried out to estimate mineral contents of some underground vegetables including potatoes, sweet-potatoes, carrots, radishes, onions, and garlics produced in Korea using ICP-AES (Inductively Coupled Plasma-Atomic Emission Spectrometry). According to the measurements, the contents of Na, Mg, Al, K, Ca, Mn, Fe, Zn, and P in Korean underground vegetables were variable depending upon producing areas and individual plants. Compared with other underground vegetables, the contents of Na in carrots and lotus roots were quite high. The contents of Cd, Ag Co. and Sr appeared to be below hazard levels. It is expected that this study can be used to calculate the mineral intake from underground vegetables.

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Effect of Inorganic Particles on Organic Fouling in Pressurized Membrane Filtration (가압식 분리막 여과에서 무기입자의 존재가 유기파울링에 미치는 영향)

  • Jang, Hoseok;Kim, Jeonghwan
    • Membrane Journal
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    • v.30 no.2
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    • pp.131-137
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    • 2020
  • In this study, effect of inorganic particles on organic fouling was investigated by a laboratory-scaled pressurized membrane filtration. In order to cause organic fouling, sodium alginate (SA) was used as a feed solution. Regardless of the presence of inorganic SiO2 particles, the complete pore blocking played an important role in determining the fouling rate during the initial period of membrane filtration. However, the formation of cake layer resulted in the membrane fouling more dominantly as filtration time progressed. In the presence of inorganic particles, both specific cake resistance and compressibility associated with the membrane fouling formed were relatively lower than that without SiO2 particles. Membrane fouling was more severe at constant flux mode of filtration than that observed at constant pressure mode probably due to the concomitant increase of compressibility of fouling layer with transmembrane pressure (TMP). It was found that the presence of SA and SiO2 particles in feed solution provided the synergistic effect on the hydraulic backwashing to reduce membrane fouling as compared to the SA solution alone without the inorganic particles.

Effect of Inorganic Pigments on the Workability of Cement Mortars (무기안료가 시멘트모르터의 유동성 미치는 영향)

  • Lee Jae-Yong;Go Seong-Seok;Lee Hyun-Soo
    • Korean Journal of Construction Engineering and Management
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    • v.1 no.2 s.2
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    • pp.63-70
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    • 2000
  • Since inorganic pigment, among admixtures used for cement composites, can raise the esthetic value of a building due to its effect of coloring, it can be assumed that the quantity consumed is expected to increase in connection with the recent trend of emphasizing the beautiful sights of the city. We carried out a flow test by changing the mix proportion of the cement mortar mixed with an inorganic pigment, water-cement ratio and pigment mixing ratio in order to present the basic materials for utilizing colored cement mortars. In construction by exploring the effect of inorganic pigments on the workability of cement mortar. In case of red pigment mortar and yellow pigment mortar, the workability was found to be rapidly decreased. To secure proper workability, it is necessary to increase the amount of mixing water, or to use superplasticizer. In case of green pigment mortar, however, it recorded $-2.4{\~}6.9{\%}$, showing that there was almost no change in flow. In case of black pigment mortar, it was also confirmed that there is no need to consider workability.

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