• KIPS Transactions on Computer and Communication Systems
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• v.11 no.6
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• pp.185-192
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• 2022

Multimodal medical image fusion (MMIF) fuses two images containing different structural details generated in two different modes into a comprehensive image with saturated information, which can help doctors improve the accuracy of observation and treatment of patients' diseases. Therefore, a method based on double-layer decomposer and fine structure preservation model is proposed. Firstly, a double-layer decomposer is applied to decompose the source images into the energy layers and structure layers, which can preserve details well. Secondly, The structure layer is processed by combining the structure tensor operator (STO) and max-abs. As for the energy layers, a fine structure preservation model is proposed to guide the fusion, further improving the image quality. Finally, the fused image can be achieved by performing an addition operation between the two sub-fused images formed through the fusion rules. Experiments manifest that our method has excellent performance compared with several typical fusion methods.

• Journal of Korean Ophthalmic Optics Society
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• v.5 no.2
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• pp.33-42
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• 2000

This study was conducted for 356 customers coming to N optometrist office in Masan city in order to evaluate practice of hygienic control of contact lens storage cases. The results were as follows: 1) For disinfection of contact lens storage case, students used wetting saline solution(42.6%), exclusive wetting solution(23.0%) and 21(11.5%) of them didn't practice disinfection. Others besides students used wetting saline solution(29.1%), boiling water(27.3%) and 42(25.5%) of them didn't practice disinfection(P<0.01). 2) For storage case washing solution, 18(85.7%) out of 21 people who belong to high economic class used wetting saline solution, 3(14.3%) used exclusive wetting solution, 141(48.0%) out of 294 people who belong to middle economic class used wetting saline solution, 129(43.9%) used exclusive solution(P<0.01). 3) For wetting solution of storage case, 132(74.6%) out of 177 students used exclusive wetting solution and the rest(25.4%) used wetting saline solution, 102(64.2%) out of 159 others besides students used exclusive wetting solution, 51(32.1%) used wetting saline solution and 6(3.8%) used sold water and city water(P<0.05). 4) 66(94.3%) out of 70 contact lens storage cases were contaminated by bacteria and Serratia marcescens was isolated in 33(47.1%) out of 70 contact lens storage cases.

• Journal of Life Science
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• v.31 no.10
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• pp.960-968
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• 2021

Since microalgae research started on late 18 century, they have been recognized as one of the most important bioresources used in bioindustry. Owing to the large efforts paid to industrial application of this microorganisms, their importance on food/feed and bioactive compounds has been further extending into the environmental research areas including alternative energy resources, mitigation of the carbon emission, and waste-water treatment. However, despite the importance on their industrial application, the fundamental research field related to the long-term preservation of microalgae culture has not received much attention. However, a less labor intensive and cost-efficient preservation technology enabling biologically active and stable microalgae-culture provides a key success factor in the biotechnological application. Therefore, this study investigated various cutting-edge microalgae cryopreservation technologies currently developed so far, mainly targeting Chlorophyta, which occupies the largest taxon in the classification system of microalgae. In addition, for the development of successful cryopreservation technique, the key factors such as temperature control effect and preservative effect during cryopreservation of microalgae culture were investigated. In addition, the problems with current preservation technology that is being used in Korean domestic biological resource banks and the international microalgal resource banks are described. According to our investigation, currently no standard method for long-term preservation of microalgae is available due to their various morphological and physiological characteristics. To overcome such issues, much more efforts on fundamental research area on the identification of specific biomarker used for microalgae taxonomical classification and further systemic approaches based on strain-specific cryopreservation methods needed.

• Journal of Korean Library and Information Science Society
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• v.48 no.4
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• pp.129-151
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• 2017

Information modeling that is broadly applied in digital archiving process privides conceptual process that can be used to guide the creation of descriptions for the objects of preservation. However, it has faced with the limitations on substantially applying to the creation of preservation metadata records. This research proposes the concept of Resource Cluster in order to address these problems and efficiently describe the objects of preservation during digital archiving process. It also constructed Preservation Description Framework (PDF) based on RDF in order to substantially manifest preservation descriptions. This framework combines the structure of OAIS Reference Model and Functional Requirements for Bibliographic Records (FRBR) and can be an alternative approach to the creation of preservation metadata in more efficient and effective ways.

• The Korean Journal of Mycology
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• v.34 no.1
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• pp.54-58
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• 2006

Liquid nitrogen storage is the most effective way to preserve many fungi including what cannot be lyophilized. The use of polypropylene straws instead of cryotubes has many advantages in economy, safety, convenience, and space-saving. We, Korean Agricultural Culture Collection (KACC), established the fungal preservation methods in liquid nitrogen using polypropylene drinking straws and introduced the methods in detail.

• Journal of Conservation Science
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• v.11 no.1 s.14
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• pp.52-57
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• 2002

Although a conservation laboratory is a kind of hospital for cultural assets, it is often planned on the standard of ordinary offices. In this study, things and conditions to be considered for a new conservation laboratory were discussed and suggested briefly, for the sections of architecture, electricity and lightning, air condition, fire protection, machinery and tools. As methods of creating a workspace adequate to conservation work, the method of dividing workspace on the basis of workstand and the method of placing machinery and tools on the basis of water supply and sewage systems were explained., Because a conservation laboratory varies in its duties and functions, it seems difficult that all the standards and conditions suggested in this study be fulfilled in every case. But understanding general standards and conditions and choosing ones adequate to special functions of each laboratory will be helpful to planning a new conservation laboratory.

• Proceedings of the Korean Nuclear Society Conference
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• 1997.05a
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• pp.592-599
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• 1997

중대사고관리 전략의 하나로서 피동형-설계에 적용되고 있는 용기내부보존(IVR)기념 - 이 논문에서는 실제적으로 원자로 압력용기벽 외부냉각(ERVC)방법을 사용한다 -이 규제측면에서는 용융물의 냉각가능성 쟁점의 해결이라는 문맥에서 조감되었다; 기술측면에서는 IVR개념의 신빙성 및 유융성이 언급되었다. 덧붙여서, 이 ERVC방법들이 개량형-설계에 적용되기 위하여 요구되는 점들이 규제측면과 기술측면에서 각각 검토되었다. 이 검토결과의 바탕위에서 용융물 냉각가능성/급냉가능성의 쟁점과 관련하여 전력연구원(KEPRI) 신형원전개발센타(CARD)에서 개발중인 한국차세대원전(KNGR)-설계에서 선택될 수 있는 대안적 전략들이 제안되었다: (1) 전략1A: 젖은공동방법의 신빙성에 기반을 두는 것; (2) 전략1B: 젖은공동방법/격납건물건전성에 기반을 두는 것; (3) 전략2A : ERVC방법의 신빙성에 기만을 두는 것, (4)전략2B: ERVC방법/격납 건물건전성의 균형된 접근법에 기반을 두는 것. 마지막으로, 신형-설계적용의 관점에서 각각 규제측면과 기술측면에서 본 현황파악 및 대책마련의 권고사항이 제시되었다.

• Journal of Chest Surgery
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• v.36 no.4
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• pp.229-241
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• 2003

Background:Autogenous vein is the preferred vascular graft for patients who require coronary artery bypass surgery or peripheral arterial bypass surgery. When an autogenous vein is not available, an allograft saphenous vein can be used as an alternative conduit. Although arterial homograft has been under investigation since the beginning of this century, the viability of endothelial cells and the optimum mode of storage for the venous and arterial allografts is controversial. In addition, with the recently gained knowledge of vascular endothelial functions, such as the production of nitric oxide or thrombomodulin, the viability and antigenicity of endothelial cells are being studied again. The purpose of this study was to evaluate the viability of endothelial cells in the preserved human saphenous veins. Material and Method: The veins were stored in a $4^{\circ}C$ RPMI (Roswell Park Memorial Institute) 1640 solution including 10% fetal calf serum, for one, three, five, seven or fourteen days. After the completion of the storage period, the veins were divided into two groups: Group I: studied immediately at $4^{\circ}C$ (cold) storage (I-1, I-3, I-5, I-7, I-14), and Group II: studied after storage at $-196^{\circ}C$ liquid nitrogen tank (cryopreservation) in an RPMI 1640 solution containing 10% DMSO for two weeks (II-1, II-3, II-5, II-7, II-14). Light microscopy and scanning electron microscopy (SEM), frypan blue exclusion testing, and thrombomodulin immunohistochemistry were performed. Result: In a morphometric study using SEM, there was statistically significant increase in Gundry Score in Groups I-7, I-14, II-5, II-7, and II-14 and showed cellular destruction (p<0.05). In the thrombomodulin immunohistochemistry study, there was reactivity in Groups I-1, I-3, and I-5, but the cryopreserved group revealed decreased reactivity (p<0.05). The trypan blue exclusion testing also showed superior viability in cold storage Group I. Conclusion: Venous allografts preserved in a $4^{\circ}C$ RPMI 1640 solution showed well preserved endothelial cellular integrity and thrombomodulin expression at up to seven days of preservation. Although cryopreservation of venous allografts stored in 10% DMSO -RPMI 1640 solution maintained the endothelial cellular structure on SEM, immunohistochemistry from the thrombomodulin and trypan blue exclusion testing showed decreased viability, It remains to be seen whether the decreased thrombomodulin reactivity could be restored, and what the nature to the relationship is between thrombomodulin and long-term patency of allografts.

• Journal of Conservation Science
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• v.30 no.2
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• pp.123-136
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• 2014

Considering that decision in conservation treatment for damaged objects should consider not only various options of methodology of intervention but also possible consequences of different types of intervention, it is a difficult task to decide and propose clear and safest solution of preserving an object. In addition, it should be constantly challenged by conservators even if it is proved technique or methodology in a past treatment. Therefore, there is no absolute solution which can be applied to all practice but each decision can be different case by case. It is not possible to estimate the way how the present condition of material and environmental aspects would affect to the condition of an object in future. However if conservators keep trying to set out various ways of analysing pro and against effect of past treatments, it would be able to provide useful logics of proving efficiency and appropriateness of a certain treatment. Understanding that the advantage of laser technique is to adopt a way of cleaning an object without making a direct contact, which is different from other techniques, this paper aims at securing stability of laser techniques, although it remains a limitation in the compatibility to all other materials. This study has examined reacting process on the painted pigments against laser beam by using CLSM in order for it to display both the problems from such reacting process and the efficiency of it as a cleaning methodology. It has intended to estimate the result of laser techniques and propose the range of applicability.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2018.06a
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• pp.124-124
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• 2018

Polydopamine은 수중 접착력, 친환경 접착제, nanoparticle absorption 등 다양한 특성으로 많이 연구되고 있는 소재이다. 본 연구에서는 dopamine을 이용하여 수중 금속을 흡착시키는 thin film을 제작하였다. 종래의 Polydopamine coating 방법으로 wet coating 이 사용되고 있다. 하지만 wet 방식의 경우 시간이 오래 걸릴 뿐만 아니라 in-line, roll to roll 방식을 적용하는 것이 어렵기 때문에 생산적이지 않다. 이에 본 연구에서는 Atmospheric Pressure Plasma(APP)를 이용 하여 Polydopamine-like film을 coating 하였다. APP의 경우 vacuum system, solution tank가 필요 없고 in-line, roll to roll 방식을 적용 할 수 있기 때문에 더 경제적이고 생산적인 공정이다. 또한 기존의 Plasma polymerization 방법은 Plasma energy가 높기 때문에 source의 분자구조가 바뀌거나 atom 단위로 분해된다. source의 분자구조가 바뀌는 "Atomic polymerization", Neiswender-Rosskamp Mechanism이 적용되면 wet 방식 coating한 film과는 다른 특성을 갖게 된다. 하지만 APP polymerization은 Plasma energy가 vacuum plasma 보다 매우 낮기 때문에 stile polymerization mechanism을 구현 하는데 적합 하다. stile polymerization mechanism은 Plasma 내부에서 polymer source를 분해 성장 시켜서 Polymer film 얻는 것이 아닌 source의 분자구조가 깨지지 않으면서 polymer growing 시키는 방법이다. dopamine source의 분자구조를 최대한 유지하려고 하는 이유는 metal absorption과 같은 특성이 dopamine chemical structure에 영향을 받기 때문이다. 많은 논문들에서 dopamine의 catechol group이 metal absorption, adhesion force에 영향을 주는 주요 인자라고 주장하고 있기 때문이다. 그래서 본 논문에서는 Dopamine source의 형태를 보존하면서 Polymerization 하는 방법으로 APP process를 사용 하여 낮은 전압에서 Polydopamine-like film을 제작 하였다. APP system 의 Plasma 방전부 에 Dopamine source를 유입하기 위하여 본 논문에서는 Piezo Spray 방식을 사용 하였다. Dopamine을 evaporator 하는 것이 어렵고 chemical composition이 유사한 monomer를 사용해서 Plasma Polymerization으로 Dopamine 분자 구조를 재현하는 것도 어렵다. 그래서 본 연구에서는 Dopamine을 water에 immerse 하고 Dopamine solution을 mist 상태로 만들어서 Plasma discharge area에 유입하였다. 이러한 방법으로 만들어진 film은 Polydopamine film은 아니지만 Polydopamine film과 유사한 Chemical composition, chemical structure, metal absorption을 갖는 것을 FT-IR, SEM, XPS을 이용 하여 확인 하였다. Dopamine source의 보존에 대하여 명확하게 확인하기 위하여 FT-IR을 측정 하였다. 전압에 따른 Benzene ring, hydroxyl group의 비율을 확인 하였다. 낮은 전압으로 coating 된 Polydopamine-like film 일수록 hydroxyl group peak($3400{\sim}3000cm^{-1}$)과 비교하여 Benzene ring peak($1600{\sim}1580cm^{-1}$ and $1510{\sim}500cm^{-1}$)이 흡수를 더 많이 하는 것을 확인 할 수 있다. 이것은 Benzene ring이 파괴되지 않고 보존되는 것을 보여준다. Dopamine에서 Benzene ring은 absorption main factor인 catechol에 있는 chemical structure이다. 즉 Benzene ring peak이 높을수록 Catechol이 잘 보존 되었다는 의미 이다. Catechol의 보존은 absorption main factor가 보존 된다는 의미 이다. 이러한 Polydopamine-like film으로 As, Cr, Mg, Cu 200ppm solution에 대한 filtration 능력을 확인 하였다. As, Cr, Cu, Mg 의 제거율이 각각 약25%, 35%, 45%, 65%인 것을 확인 하였다. 이 수치는 시중에 판매되는 제품들과 비교했을 때 300%~500% 향상된 수치 이다.