• Radiation Oncology Journal
• /
• v.19 no.4
• /
• pp.301-305
• /
• 2001

Purpose : This study was peformed for the evaluation of the feasibility and toxicity of hypofractionated radiation therapy for early glottic cancer Methods and Materials : From February 1999 to February 2000, 20 patients with Histologically confirmed Stage I, II glottic cancer were enrolled into this study. There were 18 males and 2 females, the median age of the patients was 59 years. The distribution of stage distribution was as fellows; T1aN0-16 patients, T1bN0-1 patient, T2N0-3 patients. Eighteen patients underwent laryngomicroscopic biopsy only, and two patients underwent laser cordectomy. All patients received radical radiation therapy (2.5 Gy per fraction, 24 fractions, total 60 Gy). Median duration of treatment was 36 days (range $31\~45\;days$). Results : Radiation therapy were well tolerated. Most common acute reactions were odynophagia and hoarseness, and these reactions resolved after radiation therapy. There were one case of RTOG grade 3 odynophagia $(5\%)$, six cases of grade 3 hoarseness $(30\%)$. Response of radiation therapy was evaluated one month after completion of treatment. All patients revealed complete response. During follow up, total three cases of treatment failure were detected. two cases were local recurrence in 10 and 13 months of radiation therapy and one case was local recurrence and distant metastasis in 2 months of radiation therapy. Conclusion : This hypofractionated radiation therapy schedule was feasible and effective for control of early glottic cancer But longer follow up time would be required to assess the long-term disease control and the late complication by shortening radiation therapy duration.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.33 no.2
• /
• pp.181-191
• /
• 2006

NFI-C null mice demonstrated aberrant odontoblast differentiation and thus abnormal dentin formation while other tissues/organs in the body, including ameloblasts, appear to be unaffected and normal. However little is known about the mechanism of NFI-C function in odontoblast differentiation and dentin formation. Odontoblasts are tall, highly polarized cells that are responsible for formation and maintenance of the predentin and dentin. An indication of their polarity is the acquisition of specialized intercellular junctions. As preodontoblasts differentiate into odontoblasts, they are Joined and attached at the apical end by well developed terminal webs of cytoskeletal actins, and associated tight as well as adherent njunctions. In this study, in order to investigate if disruption of the NFI-C gene interferes with formation of a specific or other structural proteins of the intercellular junctions, we examined morphological characteristic of the aberrant odontoblast in NFI-C null mice using light and electron microscope. In addition, we determined the expression of major structural proteins of intercellular junctions, ZO-1 and occludin, during the differentiation of odontoblasts using immunohitochemistry. The results were as follows : 1. In light microscopy, abnormal odontoblasts of incisors of the NFI-C null mice were round in shape, lost their polarity, and trapped in osteodentin-like mineralized tissue. Mutant molars have relatively normal crowns, but short and abnormal differentiating adontoblasts in root formation area. 2. Electron microscopy of abnormal odontoblasts revealed the dissociation of the round osteoblast-like cells, the loss of their cellular polarity, and the absence of an intercellular junctional complex known as the tight junctions. 3. A mutant incisor showed labeling for ZO-1 at the proximal and distal ends of secreting ameloblasts, while staining for ZO-1 was not observed in the abnormal odontoblasts. 4. A normal incisor showed immunoreactivity for occludin in the differentiating odontoblasts. However, staining for occludin was not observed in the abnormal odontoblasts of mutant incisor. These results suggest that NFI-C gene causes dissociation of odontoblast and thus abberant odontoblast differentiation and abnormal dentin formation by interfering with the formation of intercellular junctions.

• The Journal of the Petrological Society of Korea
• /
• v.25 no.4
• /
• pp.311-324
• /
• 2016

The characteristics of the rock cleavage in Jurassic granite from Geochang were analysed. The evaluation for three quarrying planes and three rock cleavages was performed using the parameters such as (1) reduction ratio between the value of spacing and the value of length, (2) microcrack spacing frequency(N), (3) total spacing($1mm{\geq}$), (4) exponential constant(a), (5) magnitude of exponent(${\lambda}$), (6) mean spacing($S_{mean}$), (7) difference value($S_{mean}-S_{median}$) between mean spacing and median spacing($S_{median}$) and (8) density of spacing. Especially the close dependence between the above spacing parameters and the parameters from the spacing-cumulative frequency diagrams was derived. The discrimination factors representing three quarrying planes and three rock cleavages were acquired through these mutual contrast. The analysis results of the research are summarized as follows. First, the reduction ratios of frequency(N), mean value, median value, the above difference value($S_{mean}-S_{median}$) and density for three rock cleavages are in orders of G(grain, (G1 + G2)/2) < H(hardway, (H1 + H2)/2) < R(rift, (R1 + R2)/2), H < G $\ll$ R, H < G $\ll$ R, H < G < R and H < G $\ll$ R. The values of the above five parameters for three planes show the various orders of R'(rift plane) $\ll$ H'(hardway plane) < G'(grain plane), R' $\ll$ G' < H', R' < H' < G', R' < G' < H' and R' $\ll$ H' < G', respectively. Second, the values of (I) parameters(2, 3, 4 and 5) and (II) parameters(6, 7 and 8) are in orders of (I) H < G < R and (II) R < G < H. On the contrary, the values of the above two groups(I~II) of parameters for three planes show reverse orders. Third, to review the overall characteristics of the arrangement among the six diagrams, these diagrams show an order of R2 < R1 < G2 < G1 < H2 < H1 from the related chart. In other words, above six diagrams can be summarized in order of rift(R1 + R2) < grain(G1 + G2) < hardway(H1 + H2). These results indicate a relative magnitude of rock cleavage related to microcrack spacing. Especially, two parameters for each diagram, the above difference value($S_{mean}-S_{median}$) and mean spacing, could provide advanced information for prediction the order of arrangement among the diagrams. Finally, the general chart for three planes and three rock cleavages were made. From the related chart, three exponential straight lines for three rock cleavages show an order of R(R1 + R2) < G(G1 + G2) < H(H1 + H2). On the contrary, three lines for three planes show an order of H'(R2 + G2) < G'(R1 + H2) < R'(G1 + H1). Consequently, correlation of the mutually reverse order between three planes and three rock cleavages can be drawn from the related chart.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2012.08a
• /
• pp.353-353
• /
• 2012

InAs nanowires (NWs)는 나노소자스케일의 전자소자나 광전자소자를 위한 기본 단위(building block)로 사용될 수 있고, 1차원적 나노구조를 가지면서 나타나는 특별한 전기적, 광학적 특성으로 인해 전계효과 트랜지스터, 레이저, 광발광 다이오드, 가스 검출 센서 등의 많은 응용소자로 활용을 위한 연구가 진행되 있으며 주로 실리콘, 갈륨비소 기판 위에 금속유기기상 증착(MOCVD) 또는 분자선 증착 (MBE)을 이용하여 선택적 수직배열 성장 조절을 위한 연구와 특성 평가 연구가 주로 이뤄지고 있다. 본 연구에서는 InAs NWs를 MBE 장치를 이용하여 Si(111) 기판 위에 Au와 같은 촉매를 사용하지 않고 Si과 InAs의 큰 격자 불일치로 인하여 성장되는 Volmer-weber 성장 모드를 이용 하였다. InAs NW 성장모드는 Si ($5.4309{\AA}$)과 InAs ($6.0584{\AA}$) 사이에 큰 격자상수 차이를 이용하게 되는데 촉매를 사용하여 성장하는 일반적인 이종 화합물 반도체 성장 모드와 달리 액상상태가 존재하지 않고 바로 In과 As이 Si 기판 위를 이동하여 수직방향으로 성장이 이루어지는 vaporsolid(VS) 모드이다. InAs NW V-S 성장 모드는 Si 기판과의 격자 상수차에 의한 스트레스를 이용해야 하므로 Si기판 위에 존재하는 native oxide는 완벽히 제거되어야 한다. InAs NW 최적 성장 조건을 찾기위해 V/III raitio, 성장 온도, 기판표면처리 등의 성장 변수를 변화 시켜가며 실험을 수행하였다. Native oxide를 제거하기 위하여 HF와 buffered oxide etchant (BOE)를 사용하였다. InAs NWs 성장조건은 Indium flux를 고정 시키고 V/III ratio는 50~400까지 변화를 주었다. V/III ratio를 200으로 고정을 시키고 성장온도를 $375{\sim}470^{\circ}C$에서 성장 하였다. 이 때 InAs NWs는 $430^{\circ}C$에서 가장 높은 밀도와 aspect ratio를 얻을 수 있었다. Arsenic flux에 대해서는 많을 수록 좋은 aspect ratio를 얻을 수 있었다. 하지만 InAs 구조의 절대 부피는 거의 같다는 것을 확인 할 수 있었고 이는 온도와 V/III ratio가 Indium adatom의 surface migration length에 대하여 중요한 요소로 작용되는 것을 알 수 있었다.

• Economic and Environmental Geology
• /
• v.36 no.3
• /
• pp.171-176
• /
• 2003

The fate and behavior of polycyclic aromatic hydrocarbons(PAHs) and heavy metals in the environment are mainly controlled by their interactions with various components of soils and sediments. Due to their large surface area and abundance in many soils, smectites may greatly influence the fate and transport of the contaminants. In our experiment, PAH sorption by hexadecyltimethylammonium(HDTMA)-modified smectite linearly increased in proportion to the amount of HDTMA added on the clay. However, trimethylammonium(TMA)-modified smectite did not show superiority in its sorption of PAH compared with the HDTMA-smectite or dodecyltrimethylammonium(DTMA)- smectite. Meanwhile, the smectites modified with the same cationic surfactants adsorbed Cd$^{2＋}$(heavy metal) significantly from water at low surfactant loading level, but the Cd$^{2＋}$ adsorption linearly decreased as the loading of surfactant increased. The result shows that the sorption tendency of organoclays for organic or inorganic contaminants was significantly influenced by the amount and size of the surfactants added on the clay. This reveals that the stabilization and configuration of cationic surfactant formed on the clay interlayer of different sizes may be an important factor in controlling the sorptive capacity of each pollutant in the environment.

• Journal of the Korean Wood Science and Technology
• /
• v.34 no.6
• /
• pp.1-11
• /
• 2006

Grafted tissues were investigated using various microscopic techniques. Pinus thunbergii was used as stock and scion and autografted by cleft graft method. Histochemically, grafting processes can be proceeded by four stages: 1) formation of necrotic layer, 2) proliferation of callus, 3) development of neo-cambium from callus, and 4) restoration of new vascular xylem. Necrotic la yer composed of pectin and lignin was gradually degraded during grafting process and disappeared when new union was formed between stock and scion. A large number of starch and lipid bodies in the cytoplasm were also gradually degraded during grafting process and disappeared at the grafting interface. Nucleus and plasmodesmata were not changed. Bubble-like callus was generated from all living parenchyma cells and from the callus. The tracheary elements differentiated from the callus had either reticulate or pit-like thickenings in the secondary walls with bordered pits. Secondary cell wall thickening occurred toward filing to the void parts between reticulated secondary wall. Tracheids formed in the secondary xylem were short with irregular wall thickness. New secondary xylem cells with swirled shapes, which developed in graft union were oriented horizontally and obliquely to axis of the stem.

• Journal of Wetlands Research
• /
• v.15 no.2
• /
• pp.171-177
• /
• 2013

This study was conducted to find the leaf morphological responses of Quercus serrata and Q. aliena which are potential natural vegetation of riverine in Korea under elevated $CO_2$ and increased temperature. Rising $CO_2$ concentration was treated with 1.6 times than control(ambient) and increased temperature with $2.2^{\circ}C$ above the control(ambient) in the glass greenhouse. As a result, leaf width length, leaf lamina weight and leaf area of Q. serrata and Q. aliena was respectively increased, and number of leaves and specific leaf area(SLA) was decreased by elevated $CO_2$ and temperature. Leaf width length, leaf lamina length, leaf lamina weight, number of leaves, leaf area, and specific leaf area of Q. serrata were not statistically significant difference between control and treatment. Leaf width length and leaf weight of Q. aliena was increased, but specific leaf area was decreased. These results indicated that Q. aliena was to be sensitive than Q. serrata in response to global warming situation. According to the principal component analysis(PCA), two oak species were arranged based on factor 1 and 2 in the control and warming treatment. And change on the warming treatment was clearly distinguishable from the Q. aliena than Q. serrata.

• Tunnel and Underground Space
• /
• v.18 no.1
• /
• pp.20-32
• /
• 2008

The study shows a method called a square-inventory method, which is a better and faster method than scanline survey and window method for an analysis of slope stability. The study area is located in the Changri area, Boeun-Gun, Chungbuk, and consists of many formations of the Okcheon Supergroup. Various types of failure are observed from the phyllite including the rocks in the study area. The physical properties of meta-sedimentary rocks are that minerals of the rocks are composed of microcrystalline quartz and sericite, which are arranged parallel to bedding (or schistosity) and crenulation cleavage. Therefore, such properties affect geotechnical ones of the rock. The slope stability are analyzed by selecting 3 areas, each of which are divided into 2 or 3 slopes of $1m{\times}1m$ area that represent each of 3 investigation sites. The possibility of wedge and toppling failure is very high in all 3 areas by using square-inventory method. Although possibility of plane failure is weak in the investigation site 2, the plane failures are frequently found from the slope of site 2. The bedding (or schistosity) plane and cleavage, another types of discontinuity coexist in meta-sedimentary rocks uulike igneous rocks, and therefore are important factors to be considered together with joint structures in th ε analysis of slope stability.

• Progress in Medical Physics
• /
• v.19 no.4
• /
• pp.285-290
• /
• 2008

In this study, we have fabricated a one-dimensional fiber-optic dosimeter for electron beam therapy dosimetry. Each fiber-optic dosimeter has an organic scintillator with a plastic optical fiber and it is embedded and arrayed in the plastic phantom to measure one-dimensional high energy electron beam profile of clinical linear accelerator. The scintillating lights generated from each sensor probe are guided by plastic optical fibers to the multi-channel photodiode amplifier system. We have measured one-dimensional electron beam profiles in a PMMA phantom according to different field sizes and energies of electron beam. Also, the isodose and three-dimensional percent depth dose curves in a PMMA phantom are obtained using a one-dimensional fiber-optic dosimeter with different electron beam energies.

• Archives of design research
• /
• v.11 no.3
• /
• pp.127-134
• /
• 1998

Enterprise which is rapidly growing in Korea is hesitating because of economic depression lately. Large enterprise have been successfully growing with Korea economic growth for fifty years. But many of them have already gone bankrupt and face the crisis of management, many people look away from them. Large enterprise come to face the time which they strongly need the improvement of their image against the devalation of their one. It is more important to use external periodicals than excess PR advertisement for the improvement of the image. External periodicals is aimed at readers who is outside of company and company PR advertisement, the purpose of issuing external periodicals is to improve the image of enterprise by arranging organization, draw attention from people (PR) and produce profit by acceleration marketing. People is much interested in external periodicals(free) under the situation of IMF because they can easily get information from that. So the role of external periodicals become more important for enterprise PR. This paper shows the importance of the edit design in external periodicals. We analysed the edit design (five group) per composition factor, suggest the improvement plan. ·The distinction of cover. ·Clear, beautiful typographic arrangement. ·The specialty of Photo and illustration. · Characteristic & standard layout. Now external periodicals is getting important because it shows the idea and character of company to people (PR). So it need characteristic plan and creative layout with the impotance by the understanding of the executive in company and also more does creation & originality by edit designer day by day. External periodicals should be not only the improvement of the image but also leading information paper which sensitively cope which an age by news and editing which can match people's need.