• Bio news
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• no.1
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• pp.17-18
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• 2003

• The Journal of the Korea institute of electronic communication sciences
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• v.6 no.6
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• pp.965-971
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• 2011

As the liver cancer in our country cancerous occurrence frequency to be the gastric cancer in the common cancer, If the case which will be discovered in early rising the treatment record was considered seriously about under the early detection. The system which it sees with the system for the early detection of the liver cancer reacts the blood of the control group other than the patient who is confirmed as the liver cancer and the liver cancer to the biochip and aptamer protein biochip profiles mechanical studying leads and it is a system which it classifies. 1149 each other it reacted blood samples of the control group other than the liver cancer patient who is composed of the total 85 samples and the liver cancer which is composed of 310 samples to the biochip which is composed with different oligo from the present paper and it was a data which it makes acquire worker the neural network it led and it analyzes the classification efficiency of the result 95.38 ~ 97.95% which it was visible.

• Applied Chemistry for Engineering
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• v.20 no.6
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• pp.571-580
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• 2009

Biochip sensing technologies offering in-situ, fast and real-time measurements in addition to portability can be powerfully utilized in a wide spectrum of research areas including environmental science, food science, medical diagnostics and drug development. In this article, we introduce current research trends and economic aspects of the development of various optical biochip technologies for the analysis of organophosphorus/carbamate pesticides in environmental samples, which is of global importance with serious consequences for both current and future generations. In particular, we will highlight recent efforts made in the creation of highly sensitive and selective optical biochip sensors in conjunction with nanobiotechnologies and microfabrication for the rapid detection of organophosphorus/carbamate pesticides.

• Bio news
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• no.2
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• pp.9-11
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• 2003

• Bio news
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• no.2
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• pp.5-6
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• 2003

• Bio news
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• no.2
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• pp.12-13
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• 2003

• Proceedings of the Korean Information Science Society Conference
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• 2006.10a
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• pp.22-27
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• 2006

압타머칩은 혈청(serum) 내의 지정된 단백질의 상대적 양을 직접 측정할 수 있는 바이오칩으로서, 의학적 질병 진단에 유용하게 사용할 수 있는 툴이다. 압타머칩 데이터 분석에는 기존의 마이크로어레이 분석기법을 그대로 적용할 수 있다. 본 논문에서는 Potential SVM(PSVM)을 이용하여, 심혈관질환 샘플 기반의 압타머칩 데이터에서 바이오마커 후보 단백질을 선정한 결과를 정리한다. PSVM은 분류 알고리즘으로서 뿐만 아니라 자질 선택(feature selection)에서도 우수한 성능을 보이는 알고리즘으로 알려져 있다. 심혈관 질환의 단계에 따라 구분한 4개 클래스, 135개 샘플로 구성된 3K 압타머칩 데이터에 대해 PSVM을 적용하여 자질을 선택하고 분류성능을 측정한 결과, 마이크로어레이에서의 자질 선택에 많이 사용되는 Gain Ratio 기법과 비교하여 보다 적은 수의 단백질 정보로 보다 나은 분류 성능을 보임을 확인하였다. 더불어, PSVM을 이용해 선택한 단백질군을 심혈관 질환 진단을 위한 바이오마커 후보로 제시한다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.5
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• pp.999-1008
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• 2012

Unlike the existing CMOS chip, ISB (Intelligent Silicon Bead) is new concept biochip equipped with optical communication and memory function. It uses the light for power of SoC CMOS and interface with external devices therefore it is possible to miniaturize a chip size and lower the cost. This paper introduces an input protocol and a design of the low power and the low area to transfer the power and the signal through a single optical signal applied from external reader device to bead chip at the same time. It is also verified through simulation and measurement. In addition, low-power PROM is designed for recording and storing ID of a chip and it is successful in obtaining the value of output according to the optical input. Through this study, a new type biochip development can be expected by solving high cost and a limit of miniaturizing a chip area problem of an existing RFID.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.2321-2322
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• 2008

무선 유도 가열기(wireless induction heating system)를 바이오칩에서 사용 될 세포 파괴 기술을 이용하였다. 자기장에 의해 발생하는 유도전류를 열원으로 이용한 것으로 교류자기장에 금속을 놓아두면 전자기 유도 현상에 의해 금속에 와전류(eddy current)가 발생하고 발생된 전류(AC)에 의해 금속이 가열된다. 이 전류는 순간적으로 강한 열을 발생시켜 바이오칩 내에서 이를 이용해 짧은 시간동안에 효과적으로 세포를 파괴하였다.

• 발명특허
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• v.28 no.12 s.330
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• pp.30-37
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• 2003