• Title/Summary/Keyword: 모델 이해

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Adsorption and Release Characteristics of Sulindac on Chitosan-based Molecularly Imprinted Functional Polymer Films (키토산 기반 분자 각인 고분자 필름의 슐린닥 흡착 및 방출 특성)

  • Yoon, Yeon-Hum;Yoon, Soon-Do;Nah, Jae Woon;Shim, Wang Geun
    • Applied Chemistry for Engineering
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    • v.30 no.2
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    • pp.233-240
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    • 2019
  • Molecular recognition technology has attracted considerable attention for improving the selectivity of a specific molecule by imprinting it on a polymer matrix. In this study, adsorption and release characteristics of chitosan based drug delivery films imprinted with sulindac (SLD) were investigated in terms of the plasticizer, temperature and pH and the results were also interpreted by the related mathematical models. The adsorption characteristics of target molecules on SLD-imprinted polymer films were better explained by the Freundlich and Sips equation than that of the Langmuir equation. The binding site energy distribution function was also useful for understanding the adsorption relationship between target molecules and polymer films. The drug release of SLD-imprinted polymer films followed the Fickian diffusion mechanism, whereas the drug release using artificial skin followed the non-Fickian diffusion behavior.

Predictors of Human Papillomavirus Vaccination of female Adolescent mothers (여성 청소년 어머니의 인유두종바이러스 예방접종 예측요인)

  • Hong, So-hyoung;Chung, Young-hae
    • Journal of Digital Convergence
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    • v.17 no.4
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    • pp.149-157
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    • 2019
  • This study is to evaluate the accuracy of a human papillomavirus(HVP) vaccination behavior model based on the health belief model. The subjects were 285 mothers of adolescent daughters and the data was collected from June to September, 2017. The data were analyzed using SPSS, AMOS programs. The results, perceived benefits had effects on the vaccinating behavior by completely mediating the intention while the perceived barriers had effects on the vaccinating behavior by partially mediating the intention. The vaccination intention was shown to be an important variable for predicting of vaccination behaviors while the perceived barrier was revealed to be the most influential factor for vaccination behaviors. These results could contribute to raise the understanding about HVP vaccination processes in the mothers of adolescent daughters and to develop strategies to enhance the HVP vaccination rate.

Immunostimulatory Effects of Blueberry Yeast Fermented Powder Against Cyclophosphamide-induced Immunosuppressed Model (Cyclophosphamide에 의한 면역저하 동물모델에서 블루베리 효모 발효 분말의 면역증강 효과)

  • Jeong, Do Youn;Yang, Hee Jong;Jeong, Su Ji;Kim, Min Guk;Yun, Chi Young;Lee, Hak Yong;Lee, Yang Hee;Shin, Dong Yeop;Yang, Yea gin;Lee, Hae Seong;Park, Young Mi
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.33 no.1
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    • pp.48-55
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    • 2019
  • Current studies have been reported that fruits such as berries may contain both antioxidant and antitumor polyphenols that may be important in this regard. We investigated the immunostimulatory effect of fermented blueberry (Vaccinium corymbosum L.) on cyclophosphamide-induced immunosuppression in animal model. Rats were administered blueberry yeast fermented powder (BYFP) at doses 30, 100, and 300 mg/kg for 4 weeks after cyclophosphamide (Cy) treatment, respectively. The immunomodulatory effect of BYFP were measured both in vitro and in vivo, and the changes of blood components were also analyzed. We found that BYFP recovered immunosuppression-mediated decreased liver, spleen, and thymus weights as well as up regulation of white blood cell, lymphocyte, and neutrophil in blood. Moreover, BYFP up-regulated IL-2, TNF-${\alpha}$, and IFN-${\gamma}$ pro-inflammatory cytokine production compared to immune suppressed control group, respectively. According to histological studies, BYFP regenerated significantly on Cy-mediated injured spleen at the high doses (BYFP 300) comparison with Cy-treated groups (immunosuppression). Collectively, these findings suggest that BYFP may have the potential as a dietary immunostimulatory agent.

Database Reverse Engineering Using Master Data in Microservice Architecture (마스터 데이터를 활용한 마이크로 서비스 아키텍처에서의 데이터베이스 리버스 엔지니어링)

  • Shin, Kwang-chul;Lee, Choon Y.
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.23 no.5
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    • pp.523-532
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    • 2019
  • Microservice architecture focuses on dividing it into small and lightweight services to build for the purpose of performing very close business functions. So it tends to concentrate only on agility, productivity, reliability, and ease of deployment of software development. Microservice architecture considers database as just a file or storage for storing and extracting data, emphasizing that data quality can be sacrificed for convenience and scalability of software development. Database reverse engineering for understanding database structure and data semantics is needed for data utilization for business decision making. However, it is difficult that reverse database engineering is applied in microservice architecture that neglects data quality. This study proposes database reverse engineering method that utilizes master data to restore the conceptual data model as a solution. The proposed method is applied to the return service database implemented by microservice architecture and verified its applicability.

Person-centered Approach to Organizational Commitment: Analyses of Korean Employees' Commitment Profiles (조직몰입에 대한 사람중심 접근: 국내 직장인들의 조직몰입 프로파일 분석)

  • Oh, Hyun-Sung;Jung, Yongsuhk;Kim, Woo-Seok
    • Journal of the Korean Data Analysis Society
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    • v.20 no.6
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    • pp.3049-3067
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    • 2018
  • Although there is a growing body of research on organizational commitment profiles based on a person-centered approach, it is not widely applied to the commitment research conducted by Korean organizational scholars yet. Therefore, in this paper, we introduced the concept and analytical methods, such as cluster analysis and latent profile analysis (LPA), of the person-centered approach. In addition, we also performed both cluster analysis and LPA to identify types of organizational commitment profiles of Korean employees based on the combination of affective, continuance and normative commitment on the sample from a range of different fields in South Korea (n = 349). Both analyses extracted two comparable sets of 6 commitment profiles. These six profiles were then contrasted with employee turnover intention. Finally, implications for commitment theory, practices and future research issues were discussed.

Exploring How to Apply Curriculum-Type Capstone Design based on Design Thinking in the Digital Healthcare Field (디지털 헬스케어 분야 디자인씽킹 기반 교과형 캡스톤디자인 적용 방안 탐색)

  • Hwang, Yunja;Jung, Hyojung
    • Journal of Practical Engineering Education
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    • v.13 no.2
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    • pp.261-270
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    • 2021
  • The purpose of this study is to develop a capstone design program by applying a design thinking methodology to the digital healthcare field to cultivate creative convergence talents with complex and practical skills and understanding of new technologies required in the era of the 4th industrial revolution. To this end, we analyzed the literature and previous studies in the field of digital healthcare and capstone design and proposed a capstone design model and application plan in the field of digital healthcare. The effectiveness was confirmed through expert review, and the effectiveness was analyzed by pilot application of the capstone design program. This is meaningful in that it can be used as an operation guide that can be used step-by-step when applying the capstone design in the digital healthcare field.

Design of Liberal Arts Subjects for Artificial Intelligence Education for Pre-Teachers in Elementary and Secondary Schools (초중등 예비교사의 인공지능 교육을 위한 교양 교과목 설계)

  • Jun, SooJin;Jeon, YongJu;Jeong, InKee
    • Journal of The Korean Association of Information Education
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    • v.25 no.5
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    • pp.859-869
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    • 2021
  • The purpose of this study was to develop an AI liberal arts subject for pre-service teachers of all majors in elementary and middle school. To this end, the main areas of the AI curriculum, sub-themes for each week, and activities were specifically designed and verified through two rounds of Delphi by 13 experts. The AI liberal arts curriculum in this study consists of three areas. Then, detailed topics for each week were confirmed, and a total of 13 weeks were arranged according to the natural flow. It was intended to help teaching and learning by arranging learning activities based on the experiential learning model according to the learning content. It is expected that this study will be used as basic data for the development of various AI education subjects for pre-service teachers in elementary and secondary schools in the future.

Estimation of Transverse Dispersion Coefficients Using Experimental and Numerical Method in River (자연하천에서 추적자 실험 및 수치모의를 통한 횡분산 계수 산정)

  • Seo, Il Won;Jung, Sung Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2017.05a
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    • pp.74-74
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    • 2017
  • 자연하천에서 수자원의 원활하고 안전한 관리에 있어서 오염물의 혼합 거동에 대한 이해는 매우 중요하다. 대부분의 자연하천의 경우 만곡부 및 합류부와 같은 복잡한 지형을 갖고 있으며 이러한 경우 하천의 흐름이 복잡한 형태를 갖게 된다. 특히 수생태계에 많은 영향을 미치는 하폐수 처리장 처리수는 대부분 1차적으로 지류로 방류되어 이후 본류로 지속적으로 유입되게 된다. 이러한 오염물질이 지류로부터 본류로 혼합되는 합류부 구간의 경우 일반적인 1차원 혼합이 아닌 횡방향을 포함하는 2차원적인 혼합 거동에 대한 분석이 필요하다. 본 연구에서는 금호강과 진천천이 좌안으로부터 오염물질이 지속적으로 유입되는 낙동강 중류구간 합류부에서의 혼합 구간의 연구를 위하여 횡분산계수 산정을 위하여 전기전도도(electrical conductivity: EC)를 이용한 농도 추적 실험을 수행하였다. 낙동강 본류에서 정해진 측선을 따라 센서가 설치된 보트를 이용하여 실시간으로 농도, 수리량 데이터를 GPS 위치 데이터와 함께 취득하였다. 또한 실험으로부터 취득한 자료를 바탕으로 2차원 이송-확산 혼합 거동 모델인 CTM-2D 수치모형을 이용하여 모의하였다. 실험 수행 결과, 지류인 금호강과 진천천의 EC 농도가 합류 전 낙동강 본류의 EC 기저농도 보다 더 높은 값을 나타내었다. 지류의 유입으로 인하여 본류 좌안 쪽에서 전기전도도의 값의 상승을 확인할 수 있었으며 하류로 이동할수록 불균등했던 전기전도도의 분포가 횡방향 혼합을 통하여 점점 균등한 분포로 전환되는 것으로 나타났다. 또한 2차원 혼합 거동 분석에 필요한 횡 분산계수 산정을 위해 모멘트법, 해석해를 이용한 추적법, 수치모형을 통한 역산법을 통해 산정하여 결과를 비교하였다. 그 결과 모멘트법의 경우 다른 방법들에 비하여 전반적으로 과소 산정하는 경향을 나타내었다.

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Meanings of Library in the Daily Life of Korean (한국인의 일상에서 도서관의 의미)

  • Lee, Jae-Whoan
    • Journal of Korean Library and Information Science Society
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    • v.51 no.4
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    • pp.25-57
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    • 2020
  • The purpose of this article is to find out the meanings of library in Korean's daily life, especially considering the ecology of Korean library. To the end this article explores the following three research questions. First, a thorough literature review is conducted to identify the true nature of library recognition in Korean's daily life. The focus is on evaluating the objective reliability of both library statistics and scholarly research on Korean's library recognition. Secondly, evaluated is the level of Korean's library recognition from a relative point of view. A comparative analysis with the library recognition of advanced nations' citizens is carried out to expiscate both special features and limitations in Korean's library recognition. And finally, the indigenous factors influencing Korean's library recognition are investigated, and substantially effective solutions are prescribed to upgrade the level of Korean's library recognition.

Leaf Gas-exchange Model Parameterization and Simulation for Estimating Photosynthesis in Onion (양파 광합성 예측을 위한 잎의 기체교환모형 모수 추정)

  • Lee, Seong Eun;Moon, Kyung Hwan;Shin, Min Ji;Oh, Seo Young
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.22 no.4
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    • pp.233-238
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    • 2020
  • Process-based model (PBM), based on the interactions between endogenous physiological processes and many environmental factors, can be a powerful tool for estimating crop growth and productivity. Carbon acquisition and biomass accumulation are the main components in PBM, so it has become important to understand and integrate gas exchange process in crop model. This study aimed to assess the applicability of FvCB model (a leaf model of C3 photosynthesis proposed by Farquhar, von C aemmerer, and Berry (1980)) in onion (Allium cepa L.). For parameterization, two early-maturing onion cultivars, 'Singsingball' and 'Thunderball', grown in a temperature gradient plastic film house, were used in measuring leaf net CO2 assimilation rate (A), and then, parameter estimation was carried out for four parameters including Vcmax (maximum rate of carboxylation), Jmax (maximum rate of electron transport), TPU (rate of triose phosphate utilization), and Rd (Dark respiration rate). The gas-exchange model calibrated in this research is expected to be able to explain the photosynthetic responses of onion under various environmental conditions (R2=0.95***).