• The Journal of the Society of Stroke on Korean Medicine
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• v.18 no.1
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• pp.87-96
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• 2017

■ Objectives The purpose of this clinical study is to evaluate the effect of Korean Medical Treatment on a 79 years old Korean female with shoulder pain after stroke. ■ Methods She was treated with moxibustion, acupuncture, electroacupuncture and herbal medicine. We evaluated the improvement by Numeric Rating Scale(NRS) of shoulder pain and frequency of awakening due to shoulder pain ■ Results After 24 Days, total score of NRS was decreased from 7 to 2.1. Average sleep time was increased and waking up due to shoulder pain was decreased during the night. ■ Conclusions This study suggests that Korean medical treatment, especially Moxibustion could be effective to reduce shoulder pain and alleviate sleep disturbance. Further studies are needed.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.2
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• pp.1-10
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• 2019

Backgrounds : In 2017, National Health Insurance implemented the pilot coverage program for Chuna manual therapy(CMT). 65 Korean Medicine(KM) hospitals and clinics were selected in the program to monitor the effectiveness and patients' satisfaction of insured CMT. Objectives : This study aimed to evaluate patients' satisfaction of CMT in the pilot coverage program of National Health Insurance. Methods : Survey participants were recruited among the patients who used CMT at the designated organizations. On-line questionnaire link was sent to the smart phones of patients who agreed to participate in the survey and provide personal contact information. The questionnaire consisted of the basic charactersitics of respondents, imformation on using CMT satisfaction with CMT and willingness to recommend CMT to others. The answers that were automatically coded and saved were statistically analyzed. Results : Of 386 participants who completed the questionnaire, 92.8% satisfied or strongly satisfied with the CMT. Most frequent reason of satisfaction was 'Good effectiveness', and there was no difference in satisfaction between patients of hospital and those of clinics. Patients with the highest and the lowest level of pain satisfied more than those with other pain levels(p=0.003), but the level of copayment and reasons of CMT use did not affect the satisfaction results(p=0.405). The proportions of respondents who had willingness to recommend CMT to others and to revisit for CMT use were 97.8% and 98.8%, respectively. Conclusions : Most patients were satisfied with CMT in the pilot coverage program, and it can provide the rationale for expanding the insurance coverage of CMT to all KM hospitals and clinics.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.2
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• pp.101-115
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• 2019

Objective : This study is aimed to application possibility and status of pattern identification in middle and high school students. Method : This study was cross-sectional study. We recruited 277 students through school doctor program of Seongnam city in 2017. Male students are 66 in middle school, 32 in high school. Female students are 117 in middle school, 62 in high school. For pattern identification, we used the tool of Qui Xui Shui pattern identification in students. Students fill questionnaires in inquiry of pattern identification and Korean medicine doctor diagnosis inspection and palpation of students. Results : Among 277 students, no pattern identification were 114(41.2%). It appeared in the order of phlegm, blood deficinecy, qi deficiency, qi stagnation and qi reversal. Qi deficiency, qi stagnation, qi reversal, blood deficiency and phlegm pattern are statistically significant by gender except blood stagnation. of 277 students, 105 (37.9%) had one more pattern identification. Conclusions : This study showed possibility of Qui Xui Shui pattern for student health management. In the future, large scale follow up study will be needed to clarify the relationship of pattern identification and student's health.

• The Journal of Korean Medicine
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• v.43 no.1
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• pp.171-179
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• 2022

Objectives: The purpose of study was to report the clinical improvement of late complications of COVID-19 patient complaining of dyspnea treated with Korean medicine pulmonary rehabilitation. Methods: To assess the treatment outcomes, we used the modified medical research council scale (mMRC), 6-minute walk distance (6MWD), peak expiratory flow rate (PEFR), St. George respiratory questionnaire (SGRQ). Results: After treatments, the patient's clinical symptoms were improved with mMRC, 6MWD, PEFR, and SGRQ. Conclusions: The Korean medicine pulmonary rehabilitation was effective in the treatment of late complications of COVID-19 patient. This study suggested the possibility of Korean Medicine pulmonary rehabilitation program in the clinic for late complications of COVID-19.

• The Korea Journal of Herbology
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• v.36 no.1
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• pp.1-8
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• 2021

Objective : Citri Unshius Pericarpium (Citrus unshiu peel) has been used in Korean medicine to treat indigestion, vomiting, coughing and phlegm. This study investigated the hepatoprotective effect of ethanol extract of Citrus unshiu peel (CEE) in cadmium (CdCl2)-treated mouse model. Methods : CEE was dissolved in water and administered orally to mice once a day for 7 consecutive days. The mice were then exposed to a single intraperitoneal (i.p.) injection of cadmium (4 mg/kg body weight) to induce acute hepatotoxicity. At the end of the experiment, blood and liver tissue samples were collected, analyzed for alanine aminotransferase (ALT), aspartate aminotransferase (AST), and histopathological evaluation. Liver damage was assessed as the percentage of degenerative areas of the hepatic parenchyma, the number of degenerative hepatocytes, and the number of infiltrated inflammatory cells. Results : In cadmium-treated rats, pretreatment with CEE significantly reduced the serum ALT and AST levels associated with liver damage. Histopathologically, CEE prevented degenerative changes on the hepatic tissues including confluent necrosis, congestions and infiltration of inflammatory cells. CEE also reduced the elevation of oxidative stress markers (nitrotyrosine and 4-hydroxynonenal) and apoptosis markers (cleaved caspase-3 and cleaved PARP) positive cells. PARP protein expression in liver tissue was also restored by CEE. Conclusion : This study showed that CEE exerted antioxidant and anti-apoptotic effects against cadmium-induced liver injury. Thus, it can be concluded that CEE can be used to prevent liver damage caused by cadmium.

• The Journal of Korean Medicine
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• v.43 no.1
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• pp.33-41
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• 2022

Objectives: Drug-induced blockade of the human ether-à-go-go related gene (hERG) potassium ion channel causes acquired long QT syndrome, which is known to cause cardiac arrhythmias and be fatal. To establish safety evidence of herbal formulae, we evaluated the effects of 31 herbal formulae on hERG channel activity. Methods: The current through hERG channel was measured by changing the membrane voltage before and after treatment with 31 herbal formulae in HEK 293 cell overexpressing hERG channel using a whole-cell patch clamp system. The current-voltage curves and the activity curves were fitted, and the hERG activity and 50% inhibitory concentration (IC₅₀) according to each herbal formula were calculated. Results: Chokyungjongok-tang, Oncheong-eum, and Cheongsangbangpung-tang strongly inhibited the hERG activity, with IC₅₀ values of 67.67, 141.2, and 296.3 ㎍/mL, respectively. Yeonkyopaedok-san, Eunkyo-san, Ukgan-san gajinphibanha, Daegunjoong-tang (except Oryzae gluten), Insamyangyoung-tang, Banhahubak-tang, SokyungHwalhyul-tang, Jodeung-san, Hyeonggaeyeongyo-tang, and Bangkeehwangkee-tang weakly inhibited hERG activity, with IC₅₀ values ranging from 400 to 1000 ㎍/mL. The other 18 herbal formulae showed very weak hERG activity inhibition of less than 50% at the highest concentration (1000 ㎍/mL). Conclusion: This study provided safety information on cardiotoxicity by cardiac arrhythmia risk assessment of herbal formulae, and is expected to be a reference data for predicting the safety and risk of herbal formulae.

• The Journal of Pediatrics of Korean Medicine
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• v.36 no.4
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• pp.18-32
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• 2022

Y

• Journal of Korean Medical classics
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• v.35 no.1
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• pp.173-183
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• 2022

Objectives : The publication of a specialized medical text on a specific disease at a specific time means that the disease which had broken out previously has become a problem throughout society. In this paper, changes in perception of the pediatric infectious diseases Douchuang(痘瘡, smallpox) and Mazhen(麻疹) were examined in the medical texts, the Donguibogam, Jejungsinpyeon, Yaksandang Sinjip Uibang Geumnangjibo, and the Uijongboik. Methods : Entries on Mazhen are brief within the Donguibogam which was published before its pandemic, while in the Jejungsinpyeon, which was published after Joseon had experienced the pandemic, understanding of the disease is rather insufficient. In the text Yaksandang Sinjip Uibang Geumnangjibo, which was published in the early 19th century, there is an abundance of personal accounts on the treatment of Douchuang and Mazhen. In the Uijongboik, various treatment methods of Douchuang and Mazhen could be found. Results & Conclusions : These findings could be interpreted as reflecting a development in medical knowledge of Hongzhen(紅疹) after years of experience dealing with the disease, which had been insufficient in the past as could be found in private medical texts written after the great Hongyi(紅疫, measles) pandemic had already passed. In that time Hongzhen(紅疹) had become one of the most important pediatric diseases, and peoples' perspectives had also changed accordingly.

• Journal of Korean Medical classics
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• v.5
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• pp.137-150
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• 1992

• Journal of Society of Preventive Korean Medicine
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• v.2 no.1
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• pp.231-242
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• 1998