• 대한동의생리학회:학술대회논문집
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• 2006.02a
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• pp.33-33
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• 2006

• The Korean Nurse
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• s.4
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• pp.16-21
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• 1963

오늘날 이 Poliomyelitis란 소아질병 중에서 임상에서나 어린이를 가진 부모들이 가장 큰 관심을 가진 질병중의 하나라고 생각한다. 이것은 병 자체가 중해서 생명에 어떤 위협을 가져온다는 것보다 그 결과가 deformity 즉 불구의 몸을 만들게 된다는데 그 원인이 있다고 보겠다.

• The Journal of the Korea Contents Association
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• v.20 no.11
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• pp.501-510
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• 2020

The aim of this study was to examine the characteristics of views of life and death and spiritual wellbeing of medical and non-medical university students and to compare their correlation. To this end, 95 medical students from H University and 103 non-medical students from A University were sampled for this research. The research results are as follows: For both medical and non-medical university students, negative meaning of death was found to be most high among sub-factors of views of life and death. Medical and non-medical university students differed in death anxiety and life respect will as medical students showed lower death anxiety and higher life respect will than non-medical students. As a result of analyzing the correlation between view of life and death and the sub-factors of spiritual wellbeing, religious wellbeing showed negative correlation with meaning of death, and both existential and religious wellbeing showed positive correlation with life respect will in medical university students. The results of this study are expected to be helpful in constructing differentiated contents in biomedical ethics education for medical university students who will be exposed to medical deaths.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.544-555
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• 2017

This study was conducted to identify the factors influencing consciousness of biomedical ethics, moral sensitivity and critical thinking disposition with respect to the Code of Ethics of nurses among nursing students. A descriptive correlation research design was used for this study. The subjects were 299 nursing students in two large cities from 1 June to 31 July 2015. Collected data were analyzed using a t-test, ANOVA, Scheffe's test and stepwise multiple regression by the SPSS 22.0 program. The results revealed that female subjects comprised 86.65% of the subjects and the mean age was 21.67 years. Awareness of the Code of Ethics for nurses was positively correlated with the consciousness of biomedical ethics(p<0.001), moral sensitivity(p<0.001), and critical thinking disposition(p<0.001). However, there were negative correlations between grade(p=0.017), marital state(p=0.012), and the possibility of increasing ethical problems according to the development of bioscience(p=0.012). Significant influencing factors of the awareness of the Code of Ethics for nurses included grade(p=0.013), marital state(p=0.030), consciousness of biomedical ethics(p=0.017), moral sensitivity(p<0.001), and critical thinking disposition(p=0.001), with apower of explanation of 26.3%. The results of this study show that the consciousness of biomedical ethics, moral sensitivity and critical thinking disposition are factors influencing the code of ethics for nurses among nursing students.

• Korean Journal of Environment and Ecology
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• v.30 no.5
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• pp.908-914
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• 2016

Both interests in nature-friendly education and demands for nature experience program are steadily increasing in children education field in korea. This study aims to find out that five-sense experience-activity with healing factors of forest can have an effect on both self-efficacy and respectful recognition of life of children. 5-year-old young children were chosen as the subjects for this study. Test group participated two times a week in the special forest class in a children education institute in Chungju oo-dong while control group did not. Both test group and control group were composed of 20 young children respectively and each group were 11 boys and 9 girls respectively. The five senses experience activity program was conducted two sessions a week from 8 August to 20 September in 2016 and each session was one hour (60 minutes) long. Five senses experience activity is an activity that young children awaken their five senses in the forest, recognize seasonal change with their five senses, build up their selves and become intimate with nature. Before and after the program self- efficacy test and respectful recognition of life test were conducted and the data was analyzed using SPSS 18.0 program. The results indicated that after participating five senses experience activity program both children's self-efficacy which means having positive-thinking and self-confidence and respectful recognition of life which means valuing nature coexisting with nature were improved significantly(p<0.05). Through five senses experience activity young children felt nature freely and to their heart's content with their bodies and five senses experience activity had better positive impacts on children's self- efficacy and respectful recognition of life than classroom activities.

• Journal of Korean Philosophical Society
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• v.123
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• pp.281-307
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• 2012

In the modern society, we have come to recognize human emotions such as anxiety, fear, pain, anger, sadness, longing, desire and pleasure as important topics of philosophy. How shall we study the 'problem of emotions', or in a bigger sense, the 'problem of empathy'? With this critical mind, the research into empathy can be called as a starting point for studying the deepest feelings and thoughts of human beings in connection with the feelings of other people. Most of all, in order to understand other people and to understand human being itself, the role of sympathy or empathy has been emphasized among the problems of emotions, and this trend is especially distinctive in the philosophy of psychology. I definitely acknowledge that empathy or sympathy takes loneliness and agony away from a human being and therefore it is the starting point of communication between people. However, the very fundamental question of 'what are human beings, and who are they?' is once again reminded. In other words, this thesis focuses on the fact that humans are viewed not only as the existence with a soul or heart, but also as a "unique existence" containing something "material-, life- and spiritual", and in that sense, this world is an ecological organism that contains organic connections of humans, material things, plants and animals, which should be the point of view for approach. And it is also emphasized in this study to approach the question about human beings from the religious spirituality point of view that the society with true love for neighbors could be achieved through religious practices that provide principles and value.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.3
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• pp.247-254
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• 2021

Acne vulgaris is a chronic inflammatory skin disease related to pilosebaceous unit. In acne lesions, hyperseborrhea, dysseborrhea, inflammatory event, and an imbalance in skin microflora, particularly an increase in Cutibacterium acnes (C. acnes) colonization comparing to other bacteria, have been observed. The objective of this study was to evaluate anti-acne effects of Artemisia annua extract (AAE) on antibacterial activity related to preservation of the balance in skin microbiome, inhibition of inflammation, and reduction of excessive sebum production. When C. acnes and Staphylococcus epidermidis (S. epidermidis) were co-cultured in the presence of AAE, the reduction of C. acnes growth by AAE was greater than that of S. epidermidis. In addition, when C. acnes was cultured in a medium containing AAE (C. acnes AAE), levels of cytokines such as interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α) and IL-6 and toll-like receptors-2 activity were decreased in comparison with C. acnes cultured in a medium without AAE (C. acnes CM). Moreover, AAE significantly inhibited excessive sebum production induced by palmitic acid. These results suggest that AAE, as a natural extract with various targets, can inhibit selective growth of C. acnes and inflammatory reactions derived from C. acnes, which are the main causes of acne, and consequently can be used as a substance to alleviate acne by reducing excessive sebum formation.

• Journal of Marine Life Science
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• v.4 no.2
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• pp.45-52
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• 2019

Polycyclic aromatic hydrocarbons (PAHs) are persistent and commonly detected in marine ecosystem. They coexist with a various contaminants including heavy metals in real environment, but most studies have been still focused on single effects of these contaminants to aquatic organisms. In this study, the single and combined effects of benzy[a]pyrene (B[a]P) and HgCl₂ were investigated in the brackish water flea, Diaphanosoma celebensis. For combined effect study, three mixtures A (3:7), B (5:5), and C (7:3) of benzy[a]pyrene (B[a]P) and HgCl₂ were determined by 48 h - LC₅₀ values of single exposure. Combined effects of both chemicals were estimated by concentration addition (CA) model and independent action (IA) model. As results, 48 h - LC₅₀ values of benzy[a]pyrene (B[a]P) and HgCl₂ was 25.75 ㎍ l^-1 and 3.6 ㎍ l^-1, respectively. TU values of mixture A, B, and C were 1.06, 0.83, and 0.96, respectively, indicating additive effects of mixtures using CA model. This study will be helpful as basic data for understanding the combined effects of contaminants in marine environment.

• Herbal Formula Science
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• v.26 no.4
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• pp.295-306
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• 2018

Schisandra chinensis (SC) and Lycium chinense (LC) were widely distributed in Asia and the fruit has been used traditionally for medicinal herbs. The processing method was solid-state fermentation using Aspergillus oryzae for 48 h after stir-frying treatment at $220^{\circ}C$ for 12 min. In this study, in vitro the anti-inflammatory effect and in vivo hangover reduction were compared to unprocessed SC and LC water extract. Anti-inflammatory effects have been evaluated in pro-inflammatory mediators which were secreted by lipopolysaccharide (LPS)-induced RAW 264.7 macrophages. Nitric oxide (NO) was determined using Griess reaction. Proinflammatory cytokines such as tumor necrosis factor $(TNF)-{\alpha}$ and interleukin $(IL)-1{\beta}$ were measured by enzyme-linked immunosorbent assays (ELISA). Alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities were compared to processed SC or LC and mixtures thereof (1:1). In vivo study was compared to hangover relief in alcohol-fed mice. After administering a mixture of SC and LC (300 mg/kg) water extract (1:1), mice were fed 3 g/kg of ethanol. Serum was collected at 1, 3, and 5 h intervals to analyze ethanol and acetaldehyde levels using a colorimetric assay kit. The processed SC and LC water extracts compared to raw materials significantly inhibited LPS-induced NO and inflammatory cytokine production in RAW 264.7 cells. The results of the hangover mouse model are also consistent with anti-inflammatory effects. These results suggest that processed SC and LC extracts may be functional materials for the treatment of inflammation and hangover.

• Microbiology and Biotechnology Letters
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• v.47 no.2
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• pp.250-258
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• 2019

Peniphora sp. JS17, isolated from forest old tree, produced extracellular enzymes that decolorized human hair melanin. The JS17 strain had laccase and manganese peroxidase activity while it did not has lignin peroxidase activity. Batch culture indicated that the melanin decolorization activity of JS17 strain originated from laccase. The culture conditions to maximize the production of melanin bleaching enzymes from Peniophora sp. JS17 mycelia were investigated. Among the tested media for the laccase production, minimal medium (2% glucose, 0.2% malt extract, 0.1% $KH_2PO_4$, 0.4% $MgSO_4{\cdot}7H_2O$) showed the highest activity of laccase. Then, to optimize the culture condition for the laccase activity, the influence of various carbon and nitrogen sources was investigated in minimal medium. Among various carbon and nitrogen sources, 2% xylose and 0.4% tryptone showed the highest production of laccase, respectively. The enzyme was purified using $(NH_4)_2SO_4$ precipitation and Hitrap Q sepharose column, and the purified enzyme showed two isoenzymatic bands with molecular masses of about 70 kDa by SDS-PAGE. The melanin decolorization activity was 77% and 55% within 48 h in the presence of 1-hydroxybenzotriazole (HBT) and syringaldehyde, respectively, whereas only about 9% melanin decolorized in case of no mediator.