• 제목/요약/키워드: 김선미

검색결과 663건 처리시간 0.026초

치자(梔子)의 규격 기준 모니터링 및 HPLC 표준크로마토그램 연구 (Quality Monitoring of Specification Standard of Gardeniae Fructus in the Korean Pharmacopoeia and Studies HPLC Standard Chromatogram)

  • 김경희;김선미;신승훈;이영종;백완숙
    • 대한본초학회지
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    • 제32권2호
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    • pp.97-105
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    • 2017
  • Objectives : Gardeniae Fructus is a ripe fruit of Gardenia jasminoides Ellis, which has been used as traditional medicines for anti-inflammatory, diuretic, antipyretic, and antibacterial activity. The aim of this study was to compare of Gardeniae Fructus in South Korea collected during three years according to the standards in monographs of the Korean Pharmacopoeia Eleventh edition (KP11). Methods : 30 items of Gardeniae Fructus from two cultivation regions were classified into dried(n=15) & steamed (n=15) and tested according to the standards in monographs of the KP11. Gardeniae Fructus was carried out identification(comparison of colors, thin layer chromatography), heavy metals, residual pesticides, total ash, and assay registered at KP11. Add to we tested loss on dry, contents of ethanol-soluble extracts, and HPLC profiling. Results : In TLC chromatogram of identification test, the spot of gardenoside and geniposide were observed at $R_f$ value of about 0.3 and 0.5. Heavy metals and residual pesticides met the requirements of the standards for all samples. The results of total ash of each samples are measured maximum 4.87 %. According to HPLC for assay, the samples contain 4.80~6.10 % of geniposide and 0.45~1.83 % of gardenoside. Conclusion : We have verified the current specification standard of Gardeniae Fructus and standard that is not set. By the results, it is proposed a new draft of loss on drying and confirmed the content of gardenoside revised. HPLC standard chromatogram of Gardeniae Fructus is proposed. We hope that it will help the standardization of Gardeniae Fructus.

현장 사례로 본 공동육아나눔터의 주요 기능과 운영상 문제 및 활성화 조건 (Main Function, Management Difficulties and Activating Conditions of the Cooperative Child Care Sharing Center Based on Field Cases)

  • 이승미;김선미
    • 가족자원경영과 정책
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    • 제26권1호
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    • pp.59-73
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    • 2022
  • 이 연구는 질적 연구 방법론에 의한 현장사례연구로서, 공동육아나눔터의 주요 기능과 운영상의 문제 및 활성화 조건을 탐구한 것이다. 지역(대도시·중소도시·군단위), 개소 시기, 운영기관, 위치, 맞벌이자녀초등전담돌봄 여부, 2020년 돌봄공동체시범사업 참여 여부 등을 고려하여 전국 8지역을 사례로 선정하였다. 공동연구자가 각 센터 현장을 함께 방문하여 센터장 혹은 전담직원을 대상으로 반구조화된 질문지를 활용하여 심층면접을 진행하였다. 면접자료를 전사하여 34개의 하위범주와 12개의 범주를 구성하고, 공동육아나눔터의 주요기능과 운영상의 어려움 그리고 활성화 조건이라는 세 가지 주제를 도출하였다. 이러한 주제를 토대로 공동육아나눔터 활성화방안을 제안하였다.

ChatGPT의 기초간호학교육 활용 가능성 평가 (Evaluation of the applicability of ChatGPT in biological nursing science education)

  • 김선미;김지훈;최명진;정석희
    • Journal of Korean Biological Nursing Science
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    • 제25권3호
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    • pp.183-204
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    • 2023
  • Purpose: The purpose of this study was to evaluate the applicability of ChatGPT in biological nursing science education. Methods: This study was conducted by entering questions about the field of biological nursing science into ChatGPT versions GPT-3.5 and GPT-4 and evaluating the answers. Three questions each related to microbiology and pharmacology were entered, and the generated content was analyzed to determine its applicability to the field of biological nursing science. The questions were of a level that could be presented to nursing students as written test questions. Results: The answers generated in English had 100.0% accuracy in both GPT-3.5 and GPT-4. For the sentences generated in Korean, the accuracy rate of GPT-3.5 was 62.7%, and that of GPT-4 was 100.0%. The total number of Korean sentences in GPT-3.5 was 51, while the total number of Korean sentences in GPT-4 was 68. Likewise, the total number of English sentences in GPT-3.5 was 70, while the total number of English sentences in GPT-4 was 75. This showed that even for the same Korean or English question, GPT-4 tended to be more detailed than GPT-3.5. Conclusion: This study confirmed the advantages of ChatGPT as a tool to improve understanding of various complex concepts in the field of biological nursing science. However, as the answers were based on data collected up to 2021, a guideline reflecting the most up-to-date information is needed. Further research is needed to develop a reliable and valid scale to evaluate ChatGPT's responses.

통합기술수용이론을 이용한 금융소비자들의 인공지능 서비스 수용의도 연구 (A Study on the Intention of Financial Consumers to Accept AI Services Using UTAUT Model)

  • 김선미;손영두
    • 품질경영학회지
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    • 제50권1호
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    • pp.43-61
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    • 2022
  • Purpose: The purpose of this study was verifying factors that affect to intention to use AI financial services and finding a way of building an user oriented AI ecology. Methods: This study used the UTAUT (Unified Theory of Acceptance and Use of Technology) model with independent variables such as performance expectancy, effort expectancy, social influence, facilitating conditions, trust, personal innovativeness and AI understanding as moderating variable. The data was collected through online & offline survey with questionnaire from 330 financial customers. Results: As a result, the analysis suggested that the performance expectancy, social influence, facilitating conditions, personal innovativeness are statistically significant to the intention to use AI. It was also found that AI knowledge of users differently influence the intention to use through the moderating effect on the facilitating conditions. Conclusion: Performance expectancy, social influence, facilitating conditions, personal innovativeness have positive causation to the intention to use in AI financial service. On the facilitating conditions, unlike other variables, it was found that the user's intention to use was different by the level of AI understanding. It means that customers could have the strong intention to use AI even though they don't have enough pieces of knowledge on the factors. Customers seem to be of recognition that the technology has certain benefits for themselves. The facilitating factors are significantly affected by AI understanding and differently effect on the intention to use AI.

치기공과 학생들의 전공만족도와 자아존중감이 대학생활 스트레스에 미치는 영향 (The effect of major satisfaction and self-esteem on the college life stress of dental technology students)

  • 권은자;최에스더;김선미
    • 대한치과의료관리학회지
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    • 제11권1호
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    • pp.28-37
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    • 2023
  • In this study, in order to analyze the effects of dental technology students' degree of satisfaction with their major and sense of self-esteem on college life stress, we conducted a self-administered questionnaire for 270 dental technology students. conducted a frequency analysis, t-test, one-way ANOVA, correlation analysis, and multiple regression analysis, and the results are as follows. As a result of analyzing the degree of major satisfaction, there was a significant difference in the department satisfaction (p<.05). The average score in major satisfaction was relatively high at 3.68. As a result of analyzing the level of self-esteem, there was a significant difference in grade and department satisfaction (p<.05). The average score in self-esteem question was relatively high at 3.75. As a result of analyzing the level of college life stress, there was a significant difference in the department satisfaction (p<.05). The average score for each college life stress area was relatively low at 1.97. As a result of analyzing the correlation between college life stress, major satisfaction, and self-esteem, college life stress was found to have a significant negative (-) correlation with major satisfaction and self-esteem. As a result of a regression analysis conducted on the effect of self-esteem and major satisfaction on college life stress, the variable that most influenced college life stress was found to be the self-esteem factor.

저한성 외배엽 이형성증을 가진 소아 환자에서 의치 유지력 향상을 위한 보철 치료 전략: 두 가지 증례 보고 (Prosthetic Treatment Strategies for Improving Denture Retention in Pediatric Patients with Hypohidrotic Ectodermal Dysplasia: a Report of Two Cases)

  • 전홍주;김선미;최남기
    • 대한소아치과학회지
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    • 제50권4호
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    • pp.483-494
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    • 2023
  • 이 논문은 저한성 외배엽 이형성증(Hypohidrotic Ectodermal Dysplasia, HED)으로 인한 부분무치증을 가진 소아 환자에게 의치의 유지력 증가 방법에 관한 두 가지 증례를 보고한다. 두 환자 모두 다수의 치아 결손 및 원추형의 견치와 치조골 위축, 골격적 III급 경향이 나타났다. 첫 번째 증례에서는, 변형된 형태의 Conical-Crown Retained Denture (CCRD)를 이용해 견치를 피개하였다. 이 방법은 치아를 삭제하거나 코핑 없이 진행되었다. 두 번째 증례에서는, 심한 치조제 흡수와 함께 하악 좌측 견치가 원심으로 경사지어 맹출한 상황에서, 하이브리드 세라믹 크라운을 사용하여 견치를 수복한 후, 흡착성 원리를 이용한 클라스프 유지 가철식 의치로 변경하였다. 두 환자는 현재 보철물 유지 관리 및 성장양상을 평가하기 위해 주기적으로 치료를 받고 있다. 이 증례는 HED로 인하여 의치의 유지력이 부족한 소아 환자에게 적용된 창의적인 보철 치료 방법을 제시하였다.

독성발현경로(Adverse Outcome Pathway)를 활용한 In Silico 예측기술 연구동향 분석 (Trend of In Silico Prediction Research Using Adverse Outcome Pathway)

  • 이수진;박종서;김선미;서명원
    • 한국환경보건학회지
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    • 제50권2호
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    • pp.113-124
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    • 2024
  • Background: The increasing need to minimize animal testing has sparked interest in alternative methods with more humane, cost-effective, and time-saving attributes. In particular, in silico-based computational toxicology is gaining prominence. Adverse outcome pathway (AOP) is a biological map depicting toxicological mechanisms, composed of molecular initiating events (MIEs), key events (KEs), and adverse outcomes (AOs). To understand toxicological mechanisms, predictive models are essential for AOP components in computational toxicology, including molecular structures. Objectives: This study reviewed the literature and investigated previous research cases related to AOP and in silico methodologies. We describe the results obtained from the analysis, including predictive techniques and approaches that can be used for future in silico-based alternative methods to animal testing using AOP. Methods: We analyzed in silico methods and databases used in the literature to identify trends in research on in silico prediction models. Results: We reviewed 26 studies related to AOP and in silico methodologies. The ToxCast/Tox21 database was commonly used for toxicity studies, and MIE was the most frequently used predictive factor among the AOP components. Machine learning was most widely used among prediction techniques, and various in silico methods, such as deep learning, molecular docking, and molecular dynamics, were also utilized. Conclusions: We analyzed the current research trends regarding in silico-based alternative methods for animal testing using AOPs. Developing predictive techniques that reflect toxicological mechanisms will be essential to replace animal testing with in silico methods. In the future, since the applicability of various predictive techniques is increasing, it will be necessary to continue monitoring the trend of predictive techniques and in silico-based approaches.

집중 복합 물리치료 프로그램이 산재 외상성 어깨둘레근 손상 환자의 통증, 관절가동범위, 근력, 기능, 삶의 질과 우울증에 미치는 영향 -예비연구- (Effects of an Intensively Complex Physical Therapy Program on the Pain, Range of Motion, Muscle Strength, Function, Quality of Life, and Depression of Patients with Traumatic Rotator Cuff Injury caused by an Industrial Accident -A Pilot Study-)

  • 배영현;김선미;김민주;최준경;김경애;고문주;김영범
    • PNF and Movement
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    • 제16권2호
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    • pp.275-286
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    • 2018
  • Purpose: This study aimed to investigate the effect of an intensive rehabilitation program on the pain, range of motion (ROM), muscle strength, function, quality of life (QoL), and depression of patients with traumatic rotator cuff injury caused by an industrial accident. Methods: Seventeen patients with traumatic rotator cuff injury caused by an industrial accident participated in this study. The 12-week treatment included 30 min of manual therapy and 30 min of exercise therapy twice a day, five times a week. The outcomes were measured for evaluating the pain, ROM, muscle strength, function, QoL, and depression before the commencement of the program and after 4, 8, and 12 weeks. Results: According to the time of applying the intensive rehabilitation program, the pain (p<0.01), ROM (p<0.01), muscle strength (p<0.01), function (p<0.01), and depression (p<0.05) significantly improved with time. However, QoL was not statistically significant. Conclusion: This study confirmed the excellent effect of an intensive rehabilitation program on the pain, ROM, muscle strength, function, and depression of patients with traumatic rotator cuff injury caused by an industrial accident. However, this study was limited by the absence of a control group. This pilot study highlights the need for more extensive research with a larger sample.

혈액 투석 환자의 운동 신념, 신체활동과 삶의 질 (The Attitude on Exercise, Physical Activity and Quality of Life in Hemodialysis Patients)

  • 손현숙;이미진;강선미;한영옥;문경희;김동일;이윤주;전용관;추상희
    • Journal of Korean Biological Nursing Science
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    • 제15권1호
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    • pp.15-23
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    • 2013
  • Purpose: The purpose of this study was to identify the relationship among the attitudes on exercise, physical activity and quality of life (QOL) in hemodialysis patients. Methods: A total of 42 patients in a hemodialysis unit participated in this study. Physical activity level was measured directly by 6 minute walking test and grip strength test. Structured questionnaires were also used for measuring their attitudes on exercise, physical activity and QOL. Participants' medical records were reviewed for obtaining their biochemical and clinical information. Statistical analysis was performed using Pearson correlation, and multiple liner regression. Results: A significant positive correlation between participants' attitudes and physical activity level measured by International Physical Activity Questionnaire (IPAQ) was found. And the physical activity level measured by Korea Activity Scale/Index (KASI) was significantly related to QOL. Conclusion: This study shows that QOL of the hemodialysis patients was significantly associated with their physical activity level.

임상실습이 치위생 전공학생의 전문직 정체성에 미치는 영향 (Effect of clinical practice of dental hygiene students on professional identity)

  • 이선미;김수화
    • 한국치위생학회지
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    • 제11권2호
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    • pp.189-196
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    • 2011
  • Objectives : This study aimed to get the data necessary for dental hygiene students to perceive the need for establishing a professional identity as dental hygienists and developing a program which reinforce pride as a preliminary professional. Methods : The subjects were 695 dental hygiene students in Seoul, Gyeonggi and Chungcheong areas. The collected data were analyzed using the SPSS program. Results : 1. The professional identity of dental hygiene students was 3.02 points, and the satisfaction with institutes for practice was 2.96 points. 2. The higher the satisfaction with the major was, the higher the identity was. Also, the identity was high when the frequency of clinical practice was 1 (3.11 points) and when they selected their major which corresponds with his aptitude (3.20 points). 3. The satisfaction with clinical practice was high when they didn't have any experience in dental clinic before clinical practice and when the satisfaction with the major was high. 4. Regarding the correlation between the professional identity and the satisfaction with clinical practice, the higher the satisfaction with clinical practice, the higher the professional identity. 5. The effective variables regarding the professional identity were satisfaction with a major, satisfaction with clinical practice, and frequency of clinical practice. Conclusions : The professional identity of students may be established through school education involving clinical practice. The identity of students may affect the occupational satisfaction, the identity and the work efficiency of dental hygienists in the future. Thus, it is deemed necessary to have a continued collaborative relationship between a school and an institute for clinical practice so that students may establish their correct views and identity.