• Tuberculosis and Respiratory Diseases
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• v.45 no.2
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• pp.333-340
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• 1998

Background: Lung cancer is the leading cause of cancer over the world. P53 alteration is by far the most common genetic defect in lung cancer. The mutation of p53 protein involves the loss of inhibitory function of p53 related tumor suppressor gene and resultant oncogenesis. The analysis of p53 alterations consists of immunohistochemical stain, PCR based assay, or serologic ELISA (enzyme-linked immunosorbent assay). Methods : Serum levels of p53 mutant protein were measured in 69 cases of lung cancer (adenocarcinoma n=29, epidermoid n=16, small cell n=13, large cell n=1, undifferentiated n=1, undetermined n=9) and 42 controls of respiratory disorders using ELISA. Immunohistochemical stain in tissue was performed using monoclonal antibody of p53 in lung cancer subjects. Results: Both serum p53s in nonsmall cell cancer ($0.28{\pm}0.44ng/ml$) and in small cell cancer ($0.20{\pm}0.14ng/ml$) were not different from controls ($0.34{\pm}0.20ng/ml$). Also there was no significant difference in serum p53 according to tumor stages. P53 immunohistochemical stain showed 50% positivity overall in lung cancer. There were no close correlation between serologic level and positivity of immunohistochemical stain. Conclusion: The serologic determination of p53 mutant protein is thought to have no diagnostic role in lung cancer. Immunohistochemical stain in lung cancer specimen shows 50% positivity.

• Journal of the Korean earth science society
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• v.23 no.5
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• pp.442-453
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• 2002

A total of 64 species belonging to 23 genera of diatom fossils are identified from the Core GC 98-06 in the southern Drake Passage, Antarctica. The diatom assemblages are dominated by Actinocyclus actinochilus, Coscinodiscus asteromphalus, Eucampia antarctica, Fragilariopsis kerguelensis, Thalassiosira lentiginosa, T. ritscheri and T. anguste-lineata, which are about 73% of the assemblage. Open water species are more abundant than sea ice species in the diatom assemblages of the core. Fragilariopsis. kerguelensis and Thalassiosira lentiginosa are valuable indicators of the habitats. Especially, F. kerguelensis represent the influence of waters from the Antarctic Circumpolar Current. Sea ice taxa represents the influence of cold waters from Bransfield Strait Water and melt water from the sea-ice at during warm periods. The reworked diatoms such as Denticulopsis dimopha (Miocene) and D. hustedtii (Pliocene) are occurred with Quaternary species (Actinocyclus actinochilus, Fragilariopsis kerguelensis, Thalassiosira lentiginosa, and T. glacilis). The presence of reworked diatoms indicates the transportation of the older diatoms into the Drake passage from the circumference sediments, due to strong bottom current activity of Antarctic circumpolar deep water.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.6
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• pp.1856-1868
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• 2008

This paper is about what is the effect of cultural marketing - which is affecting business ethics and social responsibility - on corporate image and formation of brand asset, and about which is getting more influence by cultural marketing among factors that is forming corporate image and brand asset. The results are like below. First, cultural marketing activities had an indirect influence on the corporate brand asset. Second, cultural marketing had an direct influence on the corporate brand image. Third, cultural marketing had a positive impact on reminding of the brand image. Fourth, social responsibility and business ethics had an indirect influence on the brand loyalty. Fifth, corporate social responsibility and business ethics had a positive impact on the brand image. Sixth, among the corporate social responsibility, community activities played a control variables. Seventh, regarding the characteristics of the respondents it showed that there's perception gaps among marketing, responsibility and ethics as well as brand assets. All in all, cultural marketing had an indirect effect on formulating corporate brand asset by the means of corporate image. The result is pointing out the importance of establishing a strategic marketing plan that is taking harmony between the character of cultural marketing and media, continuous and long-term plan, connection with the type of the brand asset into account. Moreover, as people realized that corporate business activities are brining not only economic consequences, such as providing goods and services but also social consequences, such as uneven distribution of wealth, dirty links between business and politics, consumers' security, pollution, and etc., companies are reconsidering its own role in society. This reconsideration is called corporate social responsibility and this pushed the company to keep business ethics together with their business.

• Explosives and Blasting
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• v.24 no.2
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• pp.41-50
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• 2006

Excavation by explosives blasting necessarily involves noise and vibration, which is highly prone to face claims on the environmental and structural aspects from the neighbors. When the blasting carried out in the vicinity of a structure, the effect of blasting vibration on the stability of the structure should be carefully evaluated. In the conventional method of evaluation, an equation for blast vibration is obtained from test blasting which is later used to determine the amount of charge. This method, however, has limitations in use since it does not consider topography and change in ground conditions. In order to overcome the limitations, dynamic numerical analysis is recently used in continuum or discontinuous models, where the topography and the ground conditions can be exactly implemented. In the numerical analysis for tunnels and rock slopes, it is very uncommon to simulate multi-hole blasting. A single-hole blasting pressure is estimated and the equivalent overall pressure at the excavation face is used. This approach based on an ideal case usually does not consider the ground conditions. And this consequently results in errors in calculation. In this presentation of a case study, a new approach of using blast waves obtained in the test blast is proposed. The approach was carried out in order to improve the accuracy in calculating blasting pressure. The stability of a structure in the vicinity of a slope blasting was examined using the newly proposed method.

• Archives of design research
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• v.19 no.2 s.64
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• pp.163-172
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• 2006

Sign is one of the important factors in city and national image formation, thus requires high level of quality. However, domestic sign emphasize only the sense of attention that leads to big sized signs, thus often results in a poor coordination with the surrounding space. This situation requires employees in sign business want to learn specialized knowledge about design field. Based on these circumstances, we propose sign design software to employees in sign business field as an aid tool that can help to develop good signs in terms of functionality as well as harmony of design. Thus, in this investigation, sign simulation software application case that can design sign and apply this sign to the actual application site is presented. In order to develop this software, literature survey and preliminary studies were performed to analyze the preparation process and environment, and designed sign design element and software elements, user interrace, and finally Java software were utilized. This developed software can be used as a textbook in sign design related departments in schools, and hopefully to enhance the social recognition of sign as well as academic interest.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.26-35
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• 2016

As a potential clean energy resource, the production and consumption of hydrogen gas are expected to gradually increase, so that hydrogen related studies are also increasing. The thermal and chemical properties of hydrogen result in its high flammability; in particular, there is a high risk if leaks occur within an enclosed space. In this study, we applied the computational fluid dynamics method to conduct a numerical study on the leakage behavior of hydrogen gas and compared these numerical study results with an experimental study. The leakage hole diameter was selected as an important parameter and the hydrogen gas dispersion behavior in an enclosed space was investigated through various analytical methods. Moreover, the flammable regions were investigated as a function of the leakage time and leakage hole size. We found that the growth rate of the flammable region increases rapidly with increasing leakage hole size. We also investigated the relation between the mass flow rate and the critical time when the hydrogen gas reaches the ceiling. The analysis of the monitoring points showed that the hydrogen gas dispersion behavior is isotropic and independent of the geometry. We found that the concentration of gas in an enclosed space is affected by both the leakage flow rate and amount of gas accumulated in the enclosure.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2011.11a
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• pp.60-60
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• 2011

염색폐수의 정화에는 필연적으로 다량의 슬러지 폐기물이 발생한다. 염색폐수 슬러지는 그간 인근 공해 해상에 투기하는 해양 배출로 저렴하게 처리하였으나, 해양오염을 우려하는 국제협약(1972년 런던협약, 1996년 교토의정서)에 의하여 2008년 8월부터 배출기준이 강화되고 2012년 2월부터는 해양배출이 금지 될 예정이다. 염색폐수 슬러지의 해양 배출이 금지되면 대체 처리방법으로는 지정매립장을 통한 매립처리 방법이나 고온 소각시설에서의 소각처리 방법이 거론되고 있다. 그러나 매립처리는 슬러지 내 함유 수분으로 인한 침출수의 문제와 더불어 장기간 안정적으로 저렴하게 사용할 수 있는 대규모 처분장을 확보하기 어려운 실정이며 소각처리는 슬러지의 높은 함수율로 인해 소각 시보조 연료의 투입이 필연적으로 최근 원유가 급등 등 에너지 비용이 지속적으로 상승함을 고려할 때 소각처리비용 또한 상당한 고가가 될 것으로 예측된다. 이와 같이 슬러지 해양배출이 금지되면 섬유 염색업체들은 많은 환경비용 부담을 안을 것이다. 본 연구에서는 대규모 염색산업단지 공동폐수처리장에서 발생하는 염색폐수 슬러지의 효율적인 건조를 위해 산업단지 내의 열병합발전소에서 발생하는 보일러 폐열을 이용하였으며, 조건 특성 및 효율을 파악하기 위해 보일러 폐열의 특성을 고려하여 슬러지 두께 및 체류시간 등 건조공정 운영조건에 따른 변수별 연구를 수행하였다. 열병합발전소 보일러에서 배출되는 폐열은 온도가 $150^{\circ}C$ 정도로 기존의 슬러지 건조에서는 사용되는 $700^{\circ}C$에 비해서는 매우 저온이다. 하지만 보일러 배가스의 경우, 온도에 비해 많은 풍량을 가지고 있으므로 열량으로 환산시 충분히 가치가 있는 것으로 조사되었다. 염색폐수 슬러지의 경우, 함수율 70% 이내의 탈수 Cake 형태이므로 두께가 두꺼울수록 건조효율이 감소하였으며, 체류시간이 길어질수록 건조효율은 증가하나 20mm 이상에서는 건조효율이 급격히감소하였다. 이를 바탕으로 5톤/일 규모 슬러지 건조 Pilot Plant를 제작하여 운영하였는데, 염색폐수슬러지의 투입공정에서 슬러지와 열풍의 접촉면적을 넓혀 건조효율을 높이기 위하여 슬러지를 압출노즐을 이용하여 슬라이스 칩 형태로 제조하여 건조공정에 투입하였으며, 건조실 내에서도 건조효율의 상승을 위하여 내부열풍순환팬을 설치하여 운영하였다. Pilot 운영결과, 체류시간 52분에서 슬러지의 함수율은 70%에서 10%이하로 감소하였다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.3
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• pp.213-218
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• 2021

In this study, Kombucha, a fermented drink by adding beneficial bacteria to green tea or black tea with sugar, was classified using column chromatography, and the presence or absence of quercetin glycoside, a type of flavonoids, was confirmed through TLC. In addition, the anti-pollution effect of protecting and improving the skin from pollution was confirmed using the fraction. Keratinocytes were treated with K-QG to confirm the cell viability, showing a survival rate of 90% or more up to a concentration of 100 ㎍/mL, and the cell viability by benzo[e]pyrene and fine dust stimulation to see the anti-pollution effect was measured. At 100 ㎍/mL, the improvement rates were about 68.79% and 50.68%, respectively. In addition, as a result of confirming the expression of AhR activated by benzo[a]pyrene through Western blot, it showed an inhibition rate of about 31.08% at 100 ㎍/mL compared to the control group. Through the results of this study, K-QG is thought to be valuable as an anti-pollution functional material, protecting and improving skin irritated from benzopyrene and fine dust.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.21 no.6
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• pp.129-134
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• 2021

Recently, the demand for electricity is gradually increasing due to the rapid industrial development and the improvement of living standards. In the case of Korea, which is highly dependent on fossil fuels due to such a surge in electricity demand, reduction and freezing of greenhouse gas emissions due to international environmental regulations will immediately lead to a contraction in industrial activities. Accordingly, there are many difficulties in competition with advanced countries that want to link the environment with the country's industrial production activities, and the development of alternative energy as a countermeasure is of great interest around the world. Among these new power generation methods, small-scale power generation facilities with relatively small capacity include photovoltaic generation, wind power generation, and fuel cell generation. Among them, the fuel cell attracts the most attention in consideration of continuous operation, high power generation efficiency, and long-term durability, which are important factors for practical use. Therefore, in this paper, the fuel cell power generation system was researched and constructed by designing the power conversion circuit necessary to finally obtain the AC power used in our daily life by using the DC power generated from the fuel cell as an input.

• Journal of the Korean Institute of Landscape Architecture
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• v.47 no.2
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• pp.28-48
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• 2019

This research is aimed at identifying the perception associated with urban regeneration and predicting policy implications of future directions by analyzing the trend of urban regeneration depicted in the mass media by utilizing SNA (Semantic-Network Analysis) techniques. As the number of articles has increased, it is noted through analysis that the interrelationships between social phenomena and issues have combined to form the meaning of urban regeneration. Overall, 'urban' and 'regeneration' keywords also appeared at different periods, with 'urban' closely related to 'regeneration' starting in 1970 when urbanization was becoming more prevalent. It was analyzed that the frequency of 'urban' appeared more frequently in the early 1990s, while the frequency of 'rural' decreased sharply. Until the 1990s, the slums and the recession that appeared as side effects of urban problem-solving policies were mostly concentrated in cities. Policy discussions were conducted with the goal of improving the physical environment of cities rather than concentrating on the surrounding rural areas. The distributions of the keywords 'development' and 'regeneration' have increased quantitatively since the 1970s, and urban polarization has exploded due to the development of the external growth of cities, mirroring the trend of accelerated environmental threats. In particular, the keywords for 'regeneration' emerged mainly related to environmental problems, which led to the need for urban regeneration, and environmentally and ecologically friendly development. The emergence of "urban," "regeneration" and "environment" as keywords having to do with urban regeneration grew in the 1990s. This suggests that urban regeneration is now linked to "environment", as that has become a social issue.