• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.2
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• pp.143-148
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• 2007

This study was to investigate the mixed buckwheat flour quality by observing antimutagenic and cytotoxic effects of mixed buckwheat flour extracts using Ames test and SRB (sulforhodamine B) assay. Samples were prepared to the ratio of 100% (B1), 90% (BF1), 80% (BF2), 70% (BF3) and 60% (BF4) (w/w) flour buckwheat based on wheat flour weight. The initial pasting temperature in an amylograph was increased according to the increase of the buckwheat flour. The water absorption in farinograph decreased with the addition of buckwheat flour. The inhibition rates of B1, BF3 and BF4 extract (160 g/plate) were 45%, 37.3% and 42% against the mutagenesis of Salmonella Typhimurium TA100 induced by MNNG $(0.4{\mu}g/plate)$, respectively. In addition, the B1 at the same concentration showed 64% and 44.3% inhibition on the mutagenesis of Salmonella Typhimurium TA98 and TA100 induced by 4NQO $(0.15{\mu}g/plate)$, respectively. In SRB assay, human breast adenocarcinoma (MCF 7), human hepatocellular carcinoma (Hep3B), human stomach adonocarcinoma (AGS), human lung carcinoma (A549) and human cervical adenocarcinoma (HeLa) proliferations were inhibited by the increase in the sample concentration.

• Spatial Information Research
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• v.5 no.2
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• pp.161-175
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• 1997

In spite of intense advances in the economy and technological progress which include massive and high-rise developments, landscape resources have either been destroyed or left to deteriorate. In recent years, efforts towards landscape management have emerged in the form of legislation and policies. However, relevant computer tools have unfortunately been insufficient in the field of landscape management. In addition, although there has been much research conducted for urban landscape management, pertinent information has not been recorded or managed efficiently. Therefore, this study developed a Landscape Information System for the purpose of managing urban landscape infOlmation and analyzing visual impacts in relation to urban development projects. Main functions of the Landscape Information System consist of the following: inputting and managing the attribute data as well as graphic data, querying attributes of urban landscape, and analyzing landscape impacts of developments. A case study was conducted for downtown Seoul. Using the system, a series of visual impact analyses were implemented at major viewpoints in the area. The results have shown that valuable landscape resources could be damaged by proposed development projects. Thus, the Landscape Information System developed in this study can be used as a major tool to manage urban landscape information efficiently and as the basis for decision-making regarding landscape simulation and visual impact analysis.

• KSBB Journal
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• v.24 no.4
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• pp.410-414
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• 2009

Single-nucleotide polymorphisms (SNPs) are the DNA sequences difference among the same species in the level of nucleic acids and are widely applied in clinical fields such as personalized medicine. The routine and labor-intensive methods to determine SNPs are performing the sequence homology search by using BLAST and navigating the trace of chromatogram files generated by high-throughput DNA sequencing machine by using Chromas program. In this paper, we developed SNPchaser, a web-based program for detecting SNPs substitution and heterozygosity existence, to improve the labor-intensive method in determining SNPs. SNPchaser performed sequence alignment and visualized the suspected region of SNPs by using user's reference sequence, AB1 files, and positional information of SNPs. It simultaneously provided the results of sequences alignment and chromatogram of relevant area of SNPs to user. In addition, SNPchaser can easily determine existence of heterozygosity in SNPs area. SNPchaser is freely accessible via the web site http://www.bioinformatics.ac.kr/SNPchaser and the source codes are available for academic research purpose.

• Spatial Information Research
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• v.12 no.2
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• pp.165-179
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• 2004

With the spread of wireless internet, the interest in mobile applications and services is increasing. Korea Wireless Internet Standardization Forum has been establishing the standards for mobile platform and map service in the wireless internet environment. This study aims to present a paragon of mapping middleware that plays the role of broker for wireless internet map service: in particular, it focuses on the interoperability with generic map servers. In this study, we developed a method for applying current map servers to the wireless internet map service, and analyzed the request/response structure of the map servers which have different operation characteristics in order to allow our middleware to fully utilize the functionalities of the map servers. The middleware we developed is composed of .NET-based XML Web Services: it has a lightweight module for image map and a map representation module for choropleth map, symbol map, chart map, etc. This mapping middleware is a broker between mobile client and generic map server, and supports .NET clients and Java clients as well. Its component-based interoperability grants the extensibility for the wireless internet dedicated map servers of the future in addition to the current generic map servers.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.7 no.1
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• pp.29-37
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• 2013

The purpose of this study is to suggest the potential domestic and international market conditions vehicles for people with disabilities through a review of the literature and internet resources, and to propose a road map developing South Korean vehicles for people with disabilities taking into consideration the current state of domestic and international technology and the usage of the vehicles for people with disabilities depending on the type of disability. The results of the study are as follows: First, vehicles for people with disabilities safety standards of South Korea do not meet the safety standards of developed countries and the technology of development related vehicles for people with disabilities is not as advanced as that of developed countries. Vehicles for people with disabilities installation methods, specifications, features and safety standards should be designed to be more similar to those of Japan and the United States. Second, vehicle modifications for people with disabilities will become more common as measures directed at promoting the welfare of people with disabilities, such as travel and transportation measures, employment opportunities, education, and funding for vehicle modifications, are implemented along with laws, such as The Americans with Disabilities Act, The British Disability Discrimination Act, and Japan's barrier-free transport law, that protect people with disabilities generally. Third, through a comparative analysis of domestic and international market conditions and demands of people with disabilities in vehicle modifications, important things to pay attention by purchasing a modified vehicle for people with disabilities are the employment rate for people with disabilities and monthly income. To enable this, government agencies and industry bodies should work together through the revision of the current Disability Welfare Act or the enactment of the special law for guiding principles of Disability Welfare Act. Through the future changes in vehicles for people with disabilities-related system or society of South Korean, the annual demand of the vehicles is expected to be more than 10,000.

• Journal of the Korean Society of Marine Environment & Safety
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• v.20 no.5
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• pp.543-551
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• 2014

This study has searched to find a program in order to manage simply and practically use the expelled AtoN database from the AtoN Simulator and to support the idea decision for the AtoN placement. It examines a program that manages AtoN database through the hierarchy structure, history card and endowment with condition same as a scenario. And accomplishes this study's goal owing to realizing AtoN operational software that helps for visual, hearing sense, fixed amount verification upon AtoN placement project. The AtoN operational software contributes not only flexible control like a newly establishment, relocation etc, but also supports idea decision for AtoN placement plan through many functions such as condition search, virtual sailing and fixed amount appraisal result exhibition, etc. Through utilization of this, it is to help upon the presupposition of the impact to ship or sailor about many designs and in addition, upon the judgment of whether or not for the efficiency and appropriation of the design. It is expected to reduce possible failure costs and management costs due to AtoN design and placement plans, because to compare more various designs thru the easier verification method.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.4
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• pp.289-295
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• 2017

A. koreanum was investigated to identify the constituents possessing whitening effects. As anti-melanogenesis activities were screened for the ethanol extract and solvent fractions, n-hexane (Hex) and ethyl acetate (EtOAc) fractions showed the most potent activities. Three constituents were isolated from the n-Hex fraction of A. koreanum; kaurenoic acid (1), $16{\alpha}$-hydro-17-isovaleroyloxy-ent-kauran-19-oicacid (2), $16{\alpha}$-hydroxy-17-isovaleroyl-oxy-ent-kauran-19-oic acid (3). The chemical structures of the isolated compounds were elucidated based on the spectroscopic data including $^1H$ and $^{13}C$ NMR spectra, as well as comparison of the data to the literature values. Whitening effects were studied for the isolated compounds. Upon the anti-melanogenesis test using ${\alpha}-MSH$ stimulated B16F10 melanoma cells, the compounds 1, 2 and 3 inhibited the cellular melanogenesis and intracellular tyrosinase activities effectively. Based on these results, A. koreanum stems extract could be potentially applicable as whitening ingredients in cosmetic formulations.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.28 no.2
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• pp.219-243
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• 2017

This study aims to provide alternative strategies for promoting active engagement of users in participatory archives. It focuses on users and their active participation in digital archives beyond providing simple participation opportunities. In doing so, the study reviewed relevant literature that analyzes interpretation and development of participatory digital archives. Moreover, it examined several cases of participatory digital archives as to how they apply for user participation, policy, and service. As a general property, main participants, duration, and technology were examined. Technology was further subdivided into open source software, availability of Open API, availability of mobile web, and offline archives. Participation method was divided into active participation, hub participation, and passive participation according to degree of user participation, and the participation functions provided by each archive were compared and analyzed. In policy area, terms of use, personal information processing policy, copyright policy, collection policy, major collections, scope of collections, classification methods, and descriptive elements of each archive were discussed. Services were divided into content, search, and communication area. Based on such analysis, this study proposed ways for promoting active engagement of users in participatory digital archives in terms of participation, policy, content service, and communication service.

• Proceedings of the Korea Database Society Conference
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• 1998.09a
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• pp.293-312
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• 1998

$\square$ 정보화 혁명의 대국민 인식수단과 초고속정보통신망의 주요 응용 서비스로서 부각 $\square$ 전통적인 정보이용방법에 대한 이용자들의 인식의 변화로 도서관 활성화 방안으로써 정보통신기술의 도입 $\square$ 선진 각국의 전자도서관 구축의 국가적 추진 $\square$ 국내 초고속정보통신망의 구축과 보급 확대 $\square$ 모든 국민이 지역, 시간의 제약없이 도서관에 접근하여 필요한 자료를 획득 $\square$ 정보획득시간 단축으로 국내연구자들의 연구력 증진 $\square$ 정보화의 지역격차 해소 $\square$ 국내 도서관의 전자도서관 사업 촉진 $\square$ 주요 전자도서관의 통합연동체제를 마련 $\square$ 주요 도서관별 대상분야 조정으로 중복투자 방지 $\square$ 초고속정보통신망의 주요한 응용서비스로 가시화 - 초고속정보통신망의 선도적 대국민 가시화 - 이에 따른 민간부문의 참여 및 투자 촉진 $\square$ 국가, 산업, 국민생활 정보화의 주요한 기반 구축 $\square$ 지역적 정보불균형 해소 - 일부지역에 편중되어 있는 정보를 인터넷을 이용하여 시.공간 제약없이 제공함으로써 정보의 불균형 해소 $\square$ 전자도서관의 기본모델 제시 -전자도서관의 주요기능인 타기관간 자료연동 및 검색시스템을 구현함으로써 향후 구축되는 전자도서관의 기본모델 제시 $\square$ 전자도서관간 자료공유체제 구축 -시범사업 참여도서관간 분산 관리하고 있는 정보의 공유를 위한 표준체제 구축(중략) 것으로 나타났다.까지 증가율을 보여 주었다. 것으로 나타났다.대표하는 압밀계수의 추정이 가능할 것으로 사료된다. $O_3$/라는 결정학적 관계를 가지며 에피탁샬 성장했음을 알 수 있었다.있었다.다(p<0.05)..8800-0.6800로 각각 표시되었다.~$\pm$10 V의 측정범위에서 memory window가 계속 증가하는 것을 보여주었다./$^{\circ}C$의 고주파 유전특성을 얻었다. 얻었다.끼쳤다.보였다.다. 싸이클링 성능을 보였다.다.보였다.다.고 입력 반사손실을 그림 I, 2, 3에 각각 나타내었다. 대책을 요구하고 있다.하는 경향을 보였다. 생존율은 48시간째부터 폐사하기 시작하여 144시간째에는 전량폐사하였다. 삼투압 조절 능력을 위한 여러가지 파라메타에서 15 $\textperthousand$구는 이상이 없는 것으로 추측되나, 0 $\textperthousand$구에서는 코티졸, Na$^{+}$, K$^{+}$, Cl￣, 총단백질 및 AST에서 시간경과에 따른 삼투압 조절 능력에 문제가 있는 것으로 보여진다.c}C$에서 5시간 가열조리 후 잔존율은 각각 84.7% 및 73.3%였고, 질소가스 통기하에서는 잔존율이 88.9% 및 81.8%로 더욱 안정하였다.8% 및 12.44%, 201일 이상의 경우 13.17% 및 11.30%로 201일 이상의 유기의 경우에만 대조구와 삭제 구간에 유의적인(p<0.05) 차이를 나타내었다.는 담수(淡水)에서 10%o의 해수(海水)로 이주된지 14일(日) 이후에 신장(腎臟)에서 수축된 것으로 나타났다. 30%o의 해수(海水)에 적응(適應)된 틸라피아의 평균 신사구체(腎絲球體)의 면적은 담수(淡水)에 적응된 개체의 면적보다 유의성

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.6
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• pp.829-832
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• 2003

To develop natural food preservatives, ethanol and water extracts were prepared from the cornus (Cornus of officianalis) and antimicrobial activities were examined against 10 microoganisms which were food borne pathogens and/or food poisoning microoganisms, food-related bacteria and yeasts. Ethanol extract exhibited antimicrobial activity for the microoganisms tested, except lactic acid bacteria and yeast. Especially, minimum inhibitory concentrations (MIC) of the ethanol extracts were determined as 0.25 mg/mL against bacteria and 2 mg/mL against target lactic bacteria and yeasts. Antimicrobial activity of the ethanol extracts were not destroyed by the heating at 121$^{\circ}C$ for 15 min and not affected by pH. The ethanol extract of cornus exhibiting high antimicrobial activities were fractionated in the other of diethylether and butanol fractions to test antimicrobial activity The antimicrobial activity adjust bacteria test was highest in the ethanol fraction.