• 간의등불
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• s.7
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• pp.13-19
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• 1999

• Investigative Magnetic Resonance Imaging
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• v.3 no.2
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• pp.135-145
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• 1999

• Proceedings of the Korea Contents Association Conference
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• 2014.11a
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• pp.433-434
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• 2014

최근 간질환 검사의 비침습적인 방법으로 탄성초음파가 각광받고 있는 추세이다. 그러나 진단결과와 탄성초음파 결과 값에 따른 표준 진단 매뉴얼이 없는 실정이다. 따라서 본 연구에서는 탄성초음파 수치에 따른 간질환의 종류와 B-mode 영상 간의 경향을 알아보고자 하였다. 그리고 환자의 우측 늑간 초음파 B-mode 영상평가 파라미터인 평균, 신호 대 잡음비, 최대신호 대 잡음비, 엔트로피로 분석하고, 동일 부위에 시행한 탄성초음파 수치와의 비교를 통해 경향을 연구하였고, 그 기준을 제시하고자 하였다.

• Journal of Hospice and Palliative Care
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• v.19 no.1
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• pp.61-69
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• 2016

Purpose: It is important to alleviate care burden for terminal cancer patients and their families. This study investigated the factors associated with care burden among family caregivers (FCs) of terminally ill cancer patients. Methods: We analyzed data from 289 FCs of terminal cancer patients who were admitted to palliative care units of seven medical centers in Korea. Care burden was assessed using the Korean version of Caregiver Reaction Assessment (CRA) scale which comprises five domains. A multivariate logistic regression model with stepwise variable selection was used to identify factors associated with care burden. Results: Diverse associating factors were identified in each CRA domain. Emotional factors had broad influence on care burden. FCs with emotional distress were more likely to experience changes to their daily routine (adjusted odds ratio (aOR), 2.54; 95% confidence interval (CI), 1.29~5.02), lack of family support (aOR, 2.27; 95% CI, 1.04~4.97) and health issues (aOR, 5.44; 2.50~11.88). Family functionality clearly reflected a lack of support, and severe family dysfunction was linked to financial issues as well. FCs without religion or comorbid conditions felt more burdened. The caregiving duration and daily caregiving hours significantly predicted FCs' lifestyle changes and physical burden. FCs who were employed, had weak social support or could not visit frequently, had a low self-esteem. Conclusion: This study indicates that it is helpful to understand FCs' emotional status and family functions to assess their care burden. Thus, efforts are needed to lessen their financial burden through social support systems.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.4
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• pp.101-106
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• 2020

In the current medical field, ultrasound diagnosis can be said to be the same as a stethoscope in the past. However, due to the nature of ultrasound, it has the disadvantage that the prediction of results is uncertain depending on the skill level of the examiner. Therefore, this paper aims to improve the accuracy of liver lesion detection during ultrasound examination based on deep learning technology to solve this problem. In the proposed paper, we compared the accuracy of lesion classification using a CNN model and an ensemble model. As a result of the experiment, it was confirmed that the classification accuracy in the CNN model averaged 82.33% and the ensemble model averaged 89.9%, about 7% higher. Also, it was confirmed that the ensemble model was 0.97 in the average ROC curve, which is about 0.4 higher than the CNN model.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.547-555
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• 2019

The purpose of this study was to evaluate the usefulness of routine liver ultrasonography on the basis of the scoring system according to the morphological parameters of liver ultrasound images and the histopathological results of liver biopsy. The morphological parameters of the liver through ultrasonography were divided into liver surface, liver edge and liver parenchyma. Pathologic results of liver biopsy were classified as mild fibrosis(F1), significant fibrosis(F2), severe fibrosis(F3), and cirrhosis(F4). In conclusion, routine ultrasound examination showed a sensitive predictive factor for fibrosis with mild fibrosis (F1) to severe fibrosis (F3) were liver edge>liver parenchyma>liver surface. However, the predictive factors for detecting cirrhosis (F4) were liver parenchyma>liver surface>liver edge. The use of three variable combinations rather than individual variables in routine ultrasonography may be useful in evaluating the degree and progress of liver fibrosis.

• The Korean Journal of Nuclear Medicine
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• v.18 no.1
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• pp.33-37
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• 1984

The accuracy of liver scanning was evaluated in 124 cases with primary or metastatic liver tumors, including a few benign localized lesions and in 277 cases without such lesions. All findings were histologically verified by operation or autopsy. 1) Of the 124 cases with space occupying lesions(SOLs) in the liver, 92 cases were detected by liver scan(sensitivity 74.2%). And of the 277 cases without such lesions, 266 cases were evaluated as no SOLs(specificity 96.0%). The overall accuracy was 89.3%. 2) The authors evaluated the liver scan sensitivity in each of different diseases with SOLs. The sensitivity was 88.9% in primary liver carcinoma, 82.4% in primary liver carcinoma with cirrhosis, 88.7% in liver abscess, and 100% in hemangioma. The sensitivity was low in metastatic tumor(65.8%). 3) The sensitivity of the SOLs in the right lobe was 53.3% and left lobe 27.7%. In the interlobar area, detectability was 41.7%. 4) The authors compared the sensitivity of the liver scan with the size of the SOLs. The smaller the size of the SOLs, the lower the detectability. In the pachy lesions, the sensitivity was 46.6%.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.734-744
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• 2002

The purpose of this study was to evaluate the protective effect of Kamicheonggan-tang(KCGT) on pre-hepatocarcinogenesis induced by N-nitrosomorpholine. The studied using blood chemistry, lipidperoxidation, antioxidant, immunohistochemistry and morphological change. The results were obtained as follows. In the pre-hepatocarcinogenesis induced by NMP, serum AST, ALT, ALP and total bilirubin were not changed in NMP and NK treated group after 1 st week, but desreased in NK treated group after 4th week as compared with NMP treated 4th week group. The content of GSH was similary to in NK treated groups as compares with data of normal group. The content of MDA was increased in NK treated group after 1st and 4th week, and more increased in the NMP treated group than those of their NK treated group. The immunohistochemically, stain of GST-p, positive lesions of KCGT were significantly decreased than those of NMP treated group. The histopathologically, fat changes, nucleotic changes, oval cell and inflammatory cells in periportal were observed in NMP treated fater 4th week, but those were significantly decreased from 4th week in the NK treated group. And the enlarged nucleus was not changed in KCGT treated group, but increased in NMP treated group after 1st and 4th week. The ultrastructurally, nucleotic changes, glycogen degeneration, lipid droplet and rER fragmentation were observed in NMP treated group after 4th week, but those changes were significantly decreased from 4th week in the NK treated group. These results suggested that KCGT extracts has protective effect on prehepatocarcinogenesis by NMP, might be usefully applied for clinical treatment of hapatic disease and also it was necessary to do more studies about its mechanisms.

• KIPS Transactions on Software and Data Engineering
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• v.9 no.2
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• pp.69-76
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• 2020

In this paper, we introduce a method to visualize the contrast diffusion patterns and the dynamic vascular patterns in a contrast-enhanced ultrasound image sequence. We present an imaging technique to visualize parameters such as contrast arrival time, peak intensity time, and contrast decay time in contrast-enhanced ultrasound data. The contrast flow pattern and its velocity are important for characterizing focal liver lesions. We propose a method for representing the contrast diffusion patterns as an image. In the methods, respiratory motion may degrade the accuracy of the parametric images. Therefore, we present a respiratory motion tracking technique that uses dynamic weights and a momentum factor with respect to the respiration cycle. Through the experiment using 72 CEUS data sets, we show that the proposed method makes it possible to overcome the limitation of analysis by the naked eye and improves the reliability of the parametric images by compensating for respiratory motion in contrast-enhanced ultrasonography.

• The Journal of Internal Korean Medicine
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• v.27 no.4
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• pp.962-968
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• 2006

Background : Liver cirrhosis is a disease of the liver in which normal cells are replaced by scar tissue. This condition results in the failure of the liver to perform many of its usual functions. Liver cirrhosis includes ascites, jaundice, portal hypertension, varices etc. Objectives : This study was to see if there is a decrease in ascites of liver cirrhosis to under acupuncture and herbal treatment to test their validity. Methods : Measuring the response to treatment of ascites by giving pyengwie-san hap wieryungtang gamibang and treating the patient with acupuncture, these clinical symptoms were observed: weight, abdominal circumference, abdominal SONO, chest X-ray, and lab findings. Results : Over 18 days the daily average loss of weight and abdominal circumference 0.43kg and 0.56cm, respectively. Lab findings of liver functions showed improvement. Conclusions : This report shows a role for acupuncture and herbal treatment for treating ascites in liver cirrhosis.