• Title/Summary/Keyword: 가톨릭대학교

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Preventive Effect of Garlic Administration on Respiratory Toxicity Induced through Intratracheal Instillation of Fine Dust (PM10) in Rats (실험동물 랫드를 이용한 미세먼지 기도노출에 따른 호흡기계 독성에 대한 마늘의 예방효과 탐색)

  • Lee, YoonBum;Kim, GeunWoo;Song, YoungMin;Han, YoungHoon;Ha, ChangSu;Lee, JiSun;Kim, MinHee;Son, HyeYoung;Lee, GiYong;Heo, Yong;Kim, ChangYul
    • Journal of Environmental Health Sciences
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    • v.46 no.6
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    • pp.667-675
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    • 2020
  • Objectives: Exposure to fine dust (PM10) could contribute to the occurrence of cardiovascular disease or respiratory abnormalities. Since garlic is known to possess an anti-oxidative stress effect, the present study was performed to evaluate the effect of garlic intake on fine dust-mediated pulmonary toxicity. Methods: Rats were intratracheally instilled with fine dust at 15 mg/kg body weight (BW)/day for five days following five-day intragastric intubation of garlic at 0.7 or 1.4 g/kgBW/day, or 13.1 mg/kgBW/day S-allyl-cysteine (SAC) as a reference component in garlic. Blood and bronchoalveolar lavage fluid (BALF) were collected. Results: Deposit of fine dust was visually and histopathologically observed in the lungs. Body weight gain during the instillation period was significantly lowered in all the groups instilled with fine dust. Neutrophil numbers in blood were significantly elevated in the fine dust alone group, but this alteration was diminished in the groups administered with garlic. Levels of serum glutathione were lower in the rats instilled with fine dust alone, and this decrease in the glutathione level seems dose-dependently compensated among the groups administered with garlic. Similar findings were observed in the BALF with statistical significance. Typical pulmonary histopathological observation related with inflammation was demonstrated in the lungs of the rats exposed to fine dust alone, whereas such histopathologic findings were not improved in the groups administered with garlic. Conclusion: The present study suggests that garlic intake could alleviate fine dust-mediated pulmonary or systemic toxicities. Further investigation is necessary to delineate the mechanism of garlic-mediated effects on pulmonary function.

Effects of Early Passive ROM Exercise on ROM of Lower Extremities and Foot Edema in Hemiplegia Patients with Stroke (조기 수동적 하지 관절운동이 뇌졸중 후 편마비 환자의 하지 관절가동범위와 발부종에 미치는 효과)

  • Lee, Joo Sun;Lee, Eun Ok;Lee, Eun Ju;Kim, Haeng Su
    • Journal of Korean Clinical Nursing Research
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    • v.17 no.1
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    • pp.81-89
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    • 2011
  • Purpose: The purpose of this study was to examine the effects of early passive range of motion (ROM) exercise on ROM of lower extremities and foot edema in hemiplegic patients after stroke. Methods: The data were collected between August 2009 and April 2010 from 11 patients in the experimental group and 13 in the control group. The passive ROM exercise was performed twice a day for 2 weeks. Results: In the experimental group, ROM of lower extremities (flexion of hip, flexion of knee and ankle) increased significantly compared to that of the control group. There was no significant difference in foot edema between the two groups. Conclusion: The results indicated that the early passive ROM exercise can improve the ROM of lower extremities, but not the foot edema in patients after stroke.

Solitary Jejunal Tuberculosis with Intestinal Obstruction in an Immunocompetent Patient (면역 능력이 있는 성인에서의 장폐색을 동반한 단일 공장 결핵 1예)

  • Bae, Hyun Jin;Park, Jong Ho;Jin, Su Sin;Jung, Jiyun;Nam, Yun Jung;Kim, Da Won
    • The Korean Journal of Medicine
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    • v.93 no.6
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    • pp.556-559
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    • 2018
  • Intestinal tuberculosis is an infection of the gastrointestinal tract by the Mycobacterium tuberculosis complex. To the best of our knowledge, solitary intestinal tuberculosis accompanied by intestinal obstruction, particularly in the middle of the small intestine, is extremely rare. We report a case of solitary jejunal tuberculosis in a 49-year-old man with no underlying disease. He was admitted a few days after the onset of diffuse abdominal discomfort. Upon evaluation, we initially considered a malignancy of the distal jejunum with ileus due to the presence of a mass. Therefore, he underwent laparoscopic resection of the small bowel. Unexpectedly, the histologic specimen showed a chronic caseating granulomatous lesion with acid-fast bacilli. Ultimately, he was diagnosed with solitary jejunal tuberculosis. He was successfully treated with anti-tuberculosis drugs without any complications.

A Case of Unilateral Vocal Fold Paralysis Secondary to Sarcoidosis (사르코이드증에 의한 일측 성대 마비 1예)

  • Lee, Oh-Hyeong;Bang, Jooin;Lee, Dohee;Cho, Jung-Hae
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.30 no.1
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    • pp.61-64
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    • 2019
  • Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Vocal fold paralysis secondary to sarcoidosis is extremely rare but it can develop as a result of compressive lymphadenopathy, granulomatous infiltration, and neural involvement. We report the case of a 56-year-old woman who presented with unilateral vocal fold paralysis and enlarged supraclavicular lymph nodes. Computed tomography of the neck revealed multiple, enlarged, and matted lymph nodes at the cervical level of IV. An ultrasound-guided core needle biopsy of the lymph node was performed, and a histopathological diagnosis of sarcoidosis was made by validating the presence of noncaseating granuloma. After implementation of steroid therapy, the patient exhibited immediate recovery from vocal fold paralysis. Although an extremely rare disease, sarcoidosis should be included in the differential diagnosis of vocal fold paralysis. Accurate diagnosis and prompt steroid treatment may reduce the morbidity of patients with vocal fold paralysis secondary to sarcoidosis.

Spontaneous Discharge of a Dental Implant Displaced Into Maxillary Sinus: A Case Report (자발적으로 배출된 상악동 내 함입되었던 임플란트: 증례보고)

  • Cho, Seung-Yeon;Kim, Su-Yeon;Kim, In-Soo;Lee, Won
    • Implantology
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    • v.22 no.4
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    • pp.236-241
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    • 2018
  • This case report is to report an extraordinary case of the spontaneous discharge of a dental implant. A 45-year-old woman was referred to our department complaining of symptoms of acute Maxillary sinusitis. She underwent a computed tomography scan that revealed a dental implant dislocated in the maxillary sinus. A preoperative medical treatment [Amoxicillin - Clavulanate (375 mg) and Streptokinase-Streptodornase (12500IU)] three times a day for two weeks was administered in order to prepare her for surgery. Unexpectedly, she reported that she had discharged the implant from mouth in the early morning. Mucociliary clearance in combination with a local osteolytic inflammatory process and mucolytics therapy are the likely causes of this unusual discharge.

Unusual Lower Back Pain on the Non-Articulated Side in Patient with Bertolotti's Syndrome (가관절을 이루고 있지 않은 편측의 통증을 호소한 베르톨로티 증후군)

  • Kim, Inah;Lee, Jong In;Jang, Yongjun;Park, Hae-Yeon
    • Clinical Pain
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    • v.20 no.1
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    • pp.49-52
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    • 2021
  • Bertolotti's syndrome (BS) refers to chronic low back pain (LBP) associated with lumbosacral transitional vertebrae (LSTV). Many studies suggest that the anomalous articulation alters biomechanics, resulting in discomfort on the ipsilateral side. Herein, we present an unusual case of BS presenting pain on the non-articulated side. A 46-year-old man visited our clinic with history of chronic LBP, refractory to treatment of analgesics, modalities and manual therapies. Electrodiagnostic studies showed no evidence of lumbosacral radiculopathy. Radiographies noted unilateral pseudoarticulation of L5~S1 vertebrae, on the contralateral side of his pain. The pain improved dramatically after sacroiliac joint block and facet joint block with iliolumbar ligament infiltration on the non-articulated side. Clinicians should be cautious that the unaffected joint in BS may serve an important role in altered lumbopelvic biomechanism, since it might eventually lead to intractable chronic LBP when overlooked.

The Impact of Fear and Perception of Infection Risk on Depression among Service Workers during Covid-19 (서비스업 종사자의 코로나 19에 대한 두려움과 감염위험인식이 우울에 미치는 영향)

  • Jeon, Eun-Byeol;Baek, Eun-Mi;Cho, Se-In;Jeong, Yulliana
    • Korean Journal of Occupational Health Nursing
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    • v.31 no.1
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    • pp.1-10
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    • 2022
  • Purpose: This study aimed to examine the impact of fear and perception of infection risk on depression among service workers during prolonged Covid-19 service, and to provide basic data on the impact of COVID-19 prevention on the psychological health of service workers. Methods: Data were collected from workers nationwide from May 24 to 31, 2021. The data were analyzed using the t-test, ANOVA, Scheffé test, Pearson's correlation coefficient, and multiple regression analysis, using SPSS 28. Results: It was found that 44.3% of the participants experienced depression (PHQ-9 total scores ≥ 10) during the Covid-19 pandemic. The general characteristics of service workers that made a difference in the level of depression were health status, smoking, and perception of infection risk. Conclusion: Social support from institutions is needed to treat depression caused by Covid-19 among workers in the service sector.

Effects of a Video Exercise Program for Spinal Surgery Patients on Pain, Daily Living Function and Educational Satisfaction (동영상 운동요법이 척추수술 환자의 통증과 일상생활 기능, 교육만족도에 미치는 효과)

  • Lee, Mi Jin;Kim, Eun Suk;Kim, Herina;Lee, Sun Mi
    • Journal of Korean Clinical Nursing Research
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    • v.15 no.3
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    • pp.39-48
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    • 2009
  • Purpose: The purpose of this study was to examine the effects of a video exercise program on pain, daily living function and educational satisfaction for patients with spinal surgery. Methods: The data were collected from September 2008 to May 2009. The participants were 20 people in the experimental group and 20 in the control group. The video exercise therapy, which was 15 minutes in length, was shown twice a day for 8 weeks using a CD. Results: In the experimental group, pain decreased significantly, and daily living function and educational satisfaction increased significantly compared to the control group. Conclusion: In has been confirmed that video exercise therapy has positive effects on pain, daily living function and educational satisfaction for patients following spinal surgery.

A Case of Mucosa-Associated Lymphoid Tissue Lymphoma (MALT Lymphoma) in Hypopharynx: A Case Report (하인두에 발생한 점막 연관성 림프조직 림프종 1예: 증례 보고)

  • Min-Ju Kang;Youn-Sun Park;Ju-Eun Lee;Hyun-Bum Kim
    • Korean Journal of Head & Neck Oncology
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    • v.39 no.1
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    • pp.33-36
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    • 2023
  • Malignant lymphoma rarely occurs in the larynx and hypopharynx. Few cases of malignant lymphoma in the larynx were reported in Korea. However, malignant lymphoma in the hypopharynx had been not reported in Korea. A 68-year-old woman came to the outpatient clinic with a foreign body sensation in her throat. A round, smooth margin, bright pink-colored mass was confirmed by the laryngoscopy. The patient took neck computer tomography. A small bulging of mucosa was observed, but there was no peripheral infiltration or abnormally enlarged lymph nodes. We did excision using CO2 LASER. She was finally diagnosed with mucosa-associated lymphoid tissue lymphoma (MALT lymphoma). After diagnosis, several image studies confirmed that there was no metastatic lesion. She got only radiotherapy after that and kept a complete response state for over 2 years.