• Title/Summary/Keyword: $Q_{10}$

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A Study on the Comparison for the Child Occupant Safety from Frontal Crash Test Protocol (정면충돌 시험방법에 따른 어린이 탑승객 충돌안전성 비교연구)

  • Kim, Siwoo
    • Journal of Auto-vehicle Safety Association
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    • v.8 no.3
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    • pp.33-38
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    • 2016
  • Recently, development in vehicle safety could increase interest in children's safety in vehicle collisions. But the research of children safety in vehicle collisions is not being conducted as many as that of adult's. Especially the study for the vehicle crash was not much. This study focused on the comparison of child safety between test protocols to evaluate children's safety in crash test. Injuries of Q6 and Q10 dummy were evaluated using FFRB (Full frontal rigid barrier) test and 40% ODB (Offset deformable barrier) test with one model vehicle. Even though the limit number of test, the tendency of injury criteria of Q6 and Q10 dummy between the test protocols was not conformed but injury criteria of Q6 and Q10 were not same between FFRB and 40% ODB.

The inhibitory Effects of Coenzyme Q10 on Melanogenesis of cultured Human Melanocytes and in vivo Guinea Pig Model (Coenzyme Q10의 멜라닌 생성억제효과)

  • 황재성;박원만;안수미;강병영;이병곤;심영철
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.26 no.1
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    • pp.149-162
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    • 2000
  • Coenzyme Q10 is found in all tissues including skin and it is the well-known coenzyme for mitochondrial enzymes. The electron and proton transfer functions of the quinone ring are of fundamental importance for the oxidative phosphorylation pathway to generate energy in the cells. Coenzyme Q10 has been studied as a potent antioxidant molecule in the skin. It is involved in the skin's response to UVR irradiation. The concentration of this antioxidant in UVR exposed skin is higher than in non-exposed skin. However, recent studies have also shown that coenzyme Q10 is one of the first antioxidants to be depleted when skin is UVR-irradiated. This indicates that coenzyme Q10 is primarily involved in defense mechanisms of the skin. Therefore, we questioned whether coenzyme Q10 shows reulatory effect of melanogenesis. Here we report that coenzyme Q10 inhibits melanin neosynthesis of normal human melanocytes grown in culture, and lightens UVB-induced hyperpigmentation of the guinea pig skin in vivo. We treated human melanocytes with 0.05mM to 0.5mM of coenzyme Q10 for a total of two days. This inhibited melanin neosynthesis of cultured human melanocytes dose-dependently. The inhibitory effect of coenzyme Q10 was as effective as kojic acid or vitamin C on cultured human melanocytes. CoQ10 didn't have direct inhibitory effect on tyrosinase activity in in vitro tyrosine hydroxylase activity To further clarify the effect of coenzyme Q10 on the melanogenesis, we established UVB-induced hyperpigmentation on the shaved backs of brownish guinea pigs. The UVB intensity was 500mJ/$\textrm{cm}^2$ and the total energy dose was 1,500 mJ/$\textrm{cm}^2$. The animals were exposed to UVB radiation one times a week for three consecutive weeks. Coenzyme Q10, kojic acid, Arbutin, vitamin C(1% in vehicle) or vehicle alone as a control were then topically applied daily to the hyperpigmented areas twelve times per week far four successive weeks. The lightening effect was evaluated by visual scoring, chromameter and immunohistochemistry. Coenzyme Q10 had lightening effect on the UVB-induced hyperpigmentation without any other side effects, whereas another compounds showed weak lightening efficacies. Therefore, these results suggest that coenzyme Q10 may be useful for solving physiological hyperpigmenting problems for cosmetic purposes.

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Technology convergence analysis of e-commerce(G06Q) related patents with Artificial Intelligence (인공지능 기술이 포함된 전자상거래(G06Q) 관련 특허의 기술 융복합 분석)

  • Jaeruen Shim
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.17 no.1
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    • pp.53-58
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    • 2024
  • This study is about the technology convergence analysis of e-commerce related patents containing Artificial Intelligence applied for in Korea. The relationships between core technologies were analyzed and visualized using social network analysis. As a result of social network analysis, the core IPC codes that make up the mutual technology network in e-commerce related patents containing Artificial Intelligence were found to be G06Q, G06F, G06N, G16H, G10L, H04N, G06T, and A61B. In particular, it can be confirmed that there is an important convergence of data processing-related technologies such as [G06Q-G06F], [G06Q-G06N], and voice and image signals such as [G06Q-G10L], [G06Q-H04N], and [G06Q-G06T]. Using this research method, it is possible to identify future technology trends in e-commerce related patents and create new Business Models.

A PARTITION OF q-COMMUTING MATRIX

  • Eunmi Choi
    • East Asian mathematical journal
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    • v.39 no.3
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    • pp.279-290
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    • 2023
  • We study divisibilities of elements in the q-commuting matrix C(q). We first make a coefficient matrix Ĉ of C(q) which is independent of q, study divisibilities over Ĉ and then retrieve our findings to C(q). Finally we partition the C(q) into 2 × 2 block matrices.

Coenzyme Q10, oxidative stress markers, and sperm DNA damage in men with idiopathic oligoasthenoteratospermia

  • Alahmar, Ahmed T;Sengupta, Pallav;Dutta, Sulagna;Calogero, Aldo E.
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.2
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    • pp.150-155
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    • 2021
  • Objective: Oxidative stress (OS) plays a key role in the etiology of unexplained male infertility. Coenzyme Q10 (CoQ10) is a potent antioxidant that may improve semen quality and OS in infertile men with idiopathic oligoasthenoteratospermia (OAT), but the underlying mechanism is unknown. Therefore, the present study was undertaken to investigate the effect of CoQ10 on OS markers and sperm DNA damage in infertile patients with idiopathic OAT. Methods: This prospective controlled study included 50 patients with idiopathic OAT and 50 fertile men who served as controls. All patients underwent a comprehensive medical assessment. Patients and controls received 200 mg of oral CoQ10 once daily for 3 months. Semen and blood were collected and analyzed for sperm parameters, seminal CoQ10 levels, reactive oxygen species (ROS) levels, total antioxidant capacity, catalase, sperm DNA fragmentation (SDF), and serum hormonal profile. Results: The administration of CoQ10 to patients with idiopathic OAT significantly improved sperm quality and seminal antioxidant status and significantly reduced total ROS and SDF levels compared to pretreatment values. Conclusion: CoQ10, at a dose of 200 mg/day for 3 months, may be a potential therapy for infertile patients with idiopathic OAT, as it improved sperm parameters and reduced OS and SDF in these patients.

The Effect of Coenzyme Q10 Supplementation on Oxidative Stress Index and Antioxidant Capacity in the Elderly (Coenzyme Q10 섭취가 노인들의 혈중 산화적 스트레스 지표 및 항산화 능력에 미치는 영향)

  • Kim, Jung-Kyu;Roh, Seong-Kyu
    • Korean Journal of Exercise Nutrition
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    • v.13 no.1
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    • pp.29-35
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    • 2009
  • The purpose of this study was to investigate the effects of oral supplementation of coenzyme Q10 (CoQ10) for 4 weeks on the plasma free oxygen radical and total antioxidant capacity at resting and after one bout exercise in healthy old men. Thirty volunteers with an average (+/-SD) age of 62.59+/-5.3 years participated in this study and were divided with three groups; CoQ10 (200 mg daily) group, vitamin C & E (800mg, 400 IU daily) group, and placebo group. A cycle exercise (60% HRR) test was performed at the end of study. Blood samples were taken for the analyses at rest and pre-, post-, 30min after cycle exercise, before and after the 4 weeks of supplementation. After supplementation, there were no significant differences in the plasma free oxygen radical levels and total antioxidant capacity at resting. Plasma free oxygen radical level and total antioxidant capacity in three groups were significantly elevated after exercise, however, it did not vary significantly between groups. CoQ10 supplementation showed significant difference in total antioxidant capacity during recovery phase compared with placebo group. Our results demonstrated that supplementation of CoQ10 in healthy old men improve blood total antioxidant capacity after one bout exercise, despite no alteration of plasma free oxygen radical levels.

THE q-DEFORMED GAMMA FUNCTION AND q-DEFORMED POLYGAMMA FUNCTION

  • Chung, Won Sang;Kim, Taekyun;Mansour, Toufik
    • Bulletin of the Korean Mathematical Society
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    • v.51 no.4
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    • pp.1155-1161
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    • 2014
  • In this paper, we rederive the identity ${\Gamma}_q(x){\Gamma}_q(1-x)={\frac{{\pi}_q}{sin_q({\pi}_qx)}$. Then, we give q-analogue of Gauss' multiplication formula and study representation of q-oscillator algebra in terms of the q-factorial polynomials.

ON SOME GROWTH ANALYSIS OF COMPOSITE ENTIRE AND MEROMORPHIC FUNCTIONS FROM THE VIEW POINT OF THEIR RELATIVE (p, q)-TH TYPE AND RELATIVE (p, q)-TH WEAK TYPE

  • Biswas, Tanmay
    • Korean Journal of Mathematics
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    • v.26 no.1
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    • pp.23-41
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    • 2018
  • The main aim of this paper is to prove some results related to the growth rates of composite entire and meromorphic functions on the basis of their relative (p, q)-th order, relative (p, q)-th lower order, relative (p, q)-th type and relative (p, q)-th weak type where p and q are any two positive integers.