• Communications of the Korean Mathematical Society
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• v.33 no.1
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• pp.179-196
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• 2018

In this paper we extend the two q-additions with powers in the umbrae, define a q-multinomial-coefficient, which implies a vector version of the q-binomial theorem, and an arbitrary complex power of a JHC power series is shown to be equivalent to a special case of the first q-Lauricella function. We then present several q-analogues of hypergeometric integral formulas from the two books by Exton and the paper by Choi and Rathie. We also find multiple q-analogues of hypergeometric integral formulas from the recent paper by Kim. Finally, we prove several multiple q-hypergeometric integral formulas emanating from a paper by Koschmieder, which are special cases of more general formulas by Exton.

• Journal of the Korean Mathematical Society
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• v.58 no.1
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• pp.133-147
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• 2021

Our aim in this paper is to derive several new monotonicity properties and functional inequalities of some functions involving the q-gamma, q-digamma and q-polygamma functions. More precisely, some classes of functions involving the q-gamma function are proved to be logarithmically completely monotonic and a class of functions involving the q-digamma function is showed to be completely monotonic. As applications of these, we offer upper and lower bounds for this special functions and new sharp upper and lower bounds for the q-analogue harmonic number harmonic are derived. Moreover, a number of two-sided exponential bounding inequalities are given for the q-digamma function and two-sided exponential bounding inequalities are then obtained for the q-tetragamma function.

• Korean Journal of Mathematics
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• v.30 no.3
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• pp.443-458
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• 2022

In this paper, we apply the concept of intuitionistic Q-fuzzy set to PMS-algebras. We study the concept of intuitionistic Q-fuzzy PMS-ideals of PMS-algebras and investigate some related properties of intuitionistic Q-fuzzy PMS-ideals of PMS-algebras. We provide the relationship between an intuitionistic Q-fuzzy PMS-subalgebra and an intuitionistic Q-fuzzy PMS-ideal of a PMS-algebra. We establish a condition for an intuitionistic Q-fuzzy set in a PMS-algebra to be an intuitionistic Q-fuzzy PMS-ideal of a PMS-algebra. Characterizations of intuitionistic Q-fuzzy PMS-ideals of PMS-algebras in terms of their level sets are given.

• Environmental Analysis Health and Toxicology
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• v.29
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• pp.1.1-1.7
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• 2014

Objectives The present subacute study was designed to evaluate the effect of coenzyme Q 10 (CoQ10) in the 28 days aroclor 1254 exposure induced oxidative stress in mice brain. Methods Biochemical estimations of brain lipid peroxidation (LPO), reduced glutathione (GSH), and activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and acetyl cholinesterase (AChE), and histopathological investigations of brain tissue were carried out. Results Oral exposure of aroclor 1254 (5 mg/kg) led to significant decrease in levels of GSH, and activities of SOD, CAT, GPx, and AChE, and increase in LPO. These aberrations were restored by CoQ10 (10 mg/kg, intraperitoneal injection [IP]). This protection offered was comparable to that of L-deprenyl (1 mg/kg, IP) which served as a reference standard. Conclusions Aroclor 1254 exposure hampers the activities of various antioxidant enzymes and induces oxidative stress in the brains of Swiss albino mice. Supplementation of CoQ10 abrogates these deleterious effects of aroclor 1254. CoQ10 also apparently enhanced acetyl cholinesterase activity which reflects its influence on the cholinergic system.

• Nutrition Research and Practice
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• v.6 no.5
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• pp.414-420
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• 2012

Forty guinea pigs were divided into four groups and fed 0.04% cholesterol based control diet, plus 0.05% simvastatin, and statin plus 0.1% CoQ10 or 10% Ardisia Japonica Blume (AJB) leave powder for 4 weeks. Plasma total cholesterol levels decreased significantly in all groups fed the statin-containing diet compared with that in guinea pigs fed the control diet (P < 0.01). Plasma and liver triglycerides decreased significantly in the statin plus CoQ10 group compared with those in the control (both P < 0.05). Maximum platelet aggregation was significantly higher in the statin plus CoQ10 group than that in the other groups (P < 0.05). Na-K ATPase activity increased in the statin group and decreased in the statin plus CoQ10 group (P < 0.01). Na-K co-transport and Na passive transport decreased significantly in the control group compared with those in the other groups (both P < 0.05). Intracellular Na was highest in the statin group and lowest in the statin plus CoQ10 group and was correlated with Na-K ATPase activity. Thiobarbituric acid reactive substance production in platelet-rich plasma and liver tended to decrease in the statin plus CoQ10 group compared with those in the other groups. Plasma glutamic-pyruvic transaminase and glutamic-oxaloacetic transaminase increased significantly in the statin group compared with those in the control (P < 0.05). These result suggest that antioxidant rich AJB did not have positive effects on cardiovascular disease parameters. The statin plus CoQ10 seemed to decrease cholesterol more efficiently than that of statin alone.

• Geophysics and Geophysical Exploration
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• v.14 no.3
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• pp.249-253
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• 2011

Based on intrinsic and scattering quality factor ($Q_i^{-1}$ and$Q_s^{-1}$) obtained from the seismic data of the southeastern Korean Peninsula, the expected coda quality factor (${Q_{Cexp}}^{-1}$) was theoretically calculated using multiple scattering model, and was compared with other quality factors such as $Q_i^{-1}$, $Q_s^{-1}$, and observed $Q_C^{-1}$ obtained by single scattering model. While the ${Q_{Cexp}}^{-1}$ values are typically comparable to the $Q_i^{-1}$ values, the $Q_C^{-1}$ values are different from the ${Q_{Cexp}}^{-1}$ values except for the higher frequency. Future works require to consider depth-dependent attenuation.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.29 no.10
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• pp.104-110
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• 2015

The disturbance observer (DOB) controller has been widely used in various industrial applications since it is capable of achieving robust stability and disturbance rejection. In this paper, we study the effect of Q-filter on disturbance observer controller for Electro-Magnetic suspension (EMS) systems. We consider three Q-filters and analyze their effects on the robust stability against parameter uncertainties due to mass variation. Moreover, we investigate the influence of sensor noise for three Q-filters. According to our study, robust stability improves as the order of Q-filter decreases. On the other hand, the larger the order of Q-filter, the more the effect of sensor noise can be removed.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.4
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• pp.261-272
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• 2021

Doxorubicin (Dox) is widely used to the treatment of cancer, however, it could cause damage to gastric mucosa. To investigate the protective effects and related mechanisms of coenzyme Q10 (CoQ10) and vitamin C (VC) on Dox-induced gastric mucosal injury, we presented the survey of the 4 groups of the rats with different conditions. The results showed Dox treatment significantly induced GES-1 apoptosis, but preconditioning in GES-1 cells with VC or CoQ10 significantly inhibited the Dox-induced decrease and other harm effects, including the expression and of IκKβ, IκBα, NF-κB/p65 and tumor necrosis factor (TNF-α) in GES-1 cells. Moreover, high-throughput sequencing results showed Dox treatment increased the number of harmful gut microbes, and CoQ10 and VC treatment inhibited this effect. CoQ10 and VC treatment inhibits Dox-induced gastric mucosal injury by inhibiting the activation of the IkKB/IκBα/NF-κB/p65/TNF-α pathway, promoting anti-inflammatory effects of gastric tissue and regulating the composition of the intestinal flora.

• Biomolecules & Therapeutics
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• v.18 no.1
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• pp.99-105
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• 2010

The purpose of this study was to evaluate relative bioavailability of the coenzyme Q10 (CoQ10) in emulsion and three liposome formulations after a single oral administration (60 mg/kg) into rats. Emulsion formulation of CoQ10 was prepared by conventional method using Phospholipon 85G as an emulsifier, and three liposome formulations (neutral, anionic, and cationic) of CoQ10 were prepared by traditional lipid film hydration technique using Phospholipon 85G, cholesterol, and charge carrier lipids (1,2-dioleoyl-3-trimethylammonium-propane chloride salt for cationic liposome and 1,2-dimyristoyl-sn-glycero-3-phosphate monosodium salt for anionic liposome). Mean particle size of all CoQ10-loaded liposome was less than a micron, and size distribution of the liposome population was homogeneous. Bioavailability of CoQ10 in emulsion was 1.5 to 2.6-fold greater than liposome formulations in terms of $AUC_{0-24\;h}$. $T_{max}$ was 3 h when administered as emulsion while it was greater than 6 h in liposome formulations. Notably, it was approximately 8 h in cationic liposome. $C_{max}$ was highest in emulsion and was significantly decreased when administered as liposome. Charged liposome showed even lower $C_{max}$ than neutral liposome, especially in cationic liposome. In conclusion, therefore, it is suggested that clinicians and patients consider bioavailability issue a primary concern when choosing a CoQ10 product, especially when very high plasma level is required such as in the treatment of heart failure and Parkinson's disease.

• Clinical and Experimental Reproductive Medicine
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• v.48 no.2
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• pp.97-104
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• 2021

Male infertility has a complex etiopathology, which mostly remains elusive. Although research has claimed that oxidative stress (OS) is the most likely underlying mechanism of idiopathic male infertility, the specific treatment of OS-mediated male infertility requires further investigation. Coenzyme Q10 (CoQ10), a vitamin-like substance, has been found in measurable levels in human semen. It exhibits essential metabolic and antioxidant functions, as well as playing a vital role in mitochondrial bioenergetics. Thus, CoQ10 may be a key player in the maintenance of biological redox balance. CoQ10 concentrations in seminal plasma directly correlate with semen parameters, especially sperm count and sperm motility. Seminal CoQ10 concentrations have been shown to be altered in various male infertility states, such as varicocele, asthenozoospermia, and medical or surgical regimens used to treat male infertility. These observations imply that CoQ10 plays an important physiological role in the maintenance and amelioration of semen quality. The present article thereby aimed to review the possible mechanisms through which CoQ10 plays a role in the regulation of male reproductive function, and to concisely discuss its efficacy as an ameliorative agent in restoring semen parameters in male infertility, as well as its impact on OS markers, sperm DNA fragmentation, pregnancy, and assisted reproductive technology outcomes.