• Korean Journal of Pharmacognosy
• /
• v.48 no.3
• /
• pp.208-212
• /
• 2017

In this study, analysis of active compounds that are believed to be highly relevant to antioxidant activity was carried out on the methanol extract and its solvent fractions of Corni fructus. The DPPH radical scavenging activity for the comparison of antioxidant activity was higher in order of aqueous fraction > methanol extract > ethyl acetate fraction > n-hexane fraction. It is similar to the order of total polyphenol contents in the samples. As a result of LC-MS analysis, phenolic acid compounds such as caffeic acid, gallic acid and chlorogenic acid and lognin, which is known as a representative active ingredient of Corni fructus, were identified as active compounds. And the antioxidative activity and the total polyphenol content of the extracts and solvent fractions were found to be related to the contents of the compounds. Particularly, it was confirmed that phenolic acid such as caffeic acid contributes to the antioxidative activity of the aqueous fraction of Corni fructus methanol extract.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2004.02a
• /
• pp.182-190
• /
• 2004

An unique extraction chromatographic column (TOA: Tri-n-octylamine on Teflon powder) with a two-stage sample loading was prepared to separate Np and Pu from the environmental matrix. Np and Pu were efficiently retained in 4 M $HNO_3$ medium on the column and easily eluted with 0.02 M oxalic acid in 0.16 M HNO$_3$at $95^{\circ}C$. The separated solutions were free from most of the matrix elements and were aspirated into the ICP-MS directly. The decontamination factor for 238U is more than 104. The instrumental detection limit for 237Np was 0.46 pg mL-l ($1.2{\times}10_{-5}$Bq mL-l), and for 239Pu was 0.48 pg mL-l ($1.1{\times}10_{-3}$ Bq mL-l). The feasibility for the determination of both elements was proved by analysing IAEA-135 reference samples, the measured values agreed with the recommended reference value.

• Korean Journal Plant Pathology
• /
• v.14 no.3
• /
• pp.212-216
• /
• 1998

Capsicum pepper selections fro PI163192, PI241670, PI244670, PI271322, PI308787, PI322719, and PI369994 were confirmed to be non-hypersensitively resistant to race 3 of Xanthomonas campestris pv. vesicatoria. A resistant cultivar,‘SR’, was shown to be hypersensitive. Four Koran local cultivars, a cytoplasmic male sterile line (A-line) and its maintainer (B-line) were highly susceptible. The resistant selections and cultivars were crossed with a male sterile A-line (Smsms) and fertility of their F1 hybrids was examined by observing he pollen production, testing pollen germination, and quantifying the amount of pollen produced per anther to identify the genotype interacting with the male sterile cytoplasm. The seven resistant PI selections turned out to be restorers (N(S)MsMs) and‘SR’to be a maintainer (Nmsms).

• Journal of Environmental Science International
• /
• v.12 no.1
• /
• pp.81-86
• /
• 2003

The study was carried out to evaluate the new analytical method of phthalate esters(diethylphthalate, di-n-butylphthalate, butylbenzylphthalate, bis(2-ethylhexyl)phthalate), one of the endocrine disruptors, which were performed by GC/MS-SIM(selected ion monitoring). The phthalate esters were extracted from water samples using solid-phase extraction on $C_{18}$ columns. It investigated that the extraction recovery rate of phthalate esters with different solvents and solvent volume. The optimal solvent was dichloromethane and proper volume of dichloromethane for recovery of phthalate esters was 4 mL. There were good linearities(above $R^2$=0.9975) in the range 0.01~0.50mg/L, and the detection limits were below 0.01~0.03$\mu\textrm{g}$/L. The recovery rates, RSD and MDLs for phthalate esters were 80~114%, 5.0~8.1% and 0.03~0.11$\mu\textrm{g}$/L, respectively. This method shows a good precision of phthalate esters.

• Proceedings of the KSMRM Conference
• /
• 2003.10a
• /
• pp.33-33
• /
• 2003

목적： 확산텐서영상 획득시 확산경사자장의 방향수와 FA값, 그리고 FA값의 표준편차와의 상관관계를 조사해 보고자 하였다. 대상 및 방법： 3T MR scanner에서 정상성인 10명(남자 5명, 여자 5명)을 대상으로 걸어주는 확산강조 경사자장의 수(N = 6, 11, 23, 35, 47)를 증가시키며 확산텐서영상을 획득하였다. 획득된 영상들로부터 FA map을 만들고 주요 뇌구조물(frontal GM, putamen, posterior limb of internal capsule, thalamus 등)에 관심영역을 설정하여 FA값을 측정하였으며 그 FA값의 표준편차(sd) 를 계산하였다. 이때 사용한 펄스열은 Stejskal-Tanner type의 확산강조 경사자장이 포함된 single-shot SE EPI를 사용하였으며 영상획득시 사용한 피라미터는 다음과 같다. TR/TE=8000ms/71ms, Thickness/spacing=5/2mm, FOV=240mm, Matrix=$128{\times}128$, NEX= 1, b value=1000s/$\textrm{mm}^2$.

• Journal of Korean Society on Water Environment
• /
• v.28 no.6
• /
• pp.902-910
• /
• 2012

The photodegradation characteristics of 30 pharmaceuticals were investigated by batch experiments using Ultraviolet (UV) reactor. The investigated pharmaceuticals include antibiotics, analgesics and antiarrhythmic agents etc. Tested water was prepared by simultaneously spiking 30 pharmaceuticals into pure water, and each experiment was conducted using 3 types of UV lamps. As a result, batch experiments showed that reactions of all the investigated pharmaceuticals followed pseudo-first order reaction regardless of the applied UV lamps. Among the pharmaceuticals, Cyclophosphamide, 2-Quinoxaline carboxylic acid and Clarithromycin proved to be the most UV-resistant compounds. Contrarily, Ceftiofur, Diclofenac and Ketoprofen were easily degraded by all the UV lamps. Dissolved organic carbon (DOC) concentration hardly changed although the concentration of the pharmaceuticals concentration gradually decreased with time, indicating that the degradation of parent pharmaceuticals may produce their intermediates during UV treatment.

• Journal of Plant Biotechnology
• /
• v.6 no.3
• /
• pp.189-192
• /
• 2004

Adventitious multiple shoots were developed from leaf, petiole and internode explants of Geophila reniformis D. Don. on MS medium supplemented with various concentrations of $N^6$-benzylaminopurine (BAP) or Kinetin (KIN) alone or in combination with indole-3-acetic acid (IAA). Leaf showed maximum organogenetic potential, followed by petiole and internode. Murashige and Skoog (MS) medium supplemented with 22.22 $\mu{M}$ BAP and 4.57 $\mu{M}$ IAA induced maximum shoot buds from leaf explants. Internodal segments showed low potential of direct organogenesis. The regenerated shoots rooted the best in presence of 10.75 - 13.44 $\mu{M}$ $\alpha$-naphthalene acetic acid (NAA) along with 2.22 $\mu{M}$ BAP, and were successfully established in the field with a survival rate of 89.11%.

• Journal of Pharmaceutical Investigation
• /
• v.39 no.5
• /
• pp.373-379
• /
• 2009

This study was conducted to develop a pharmacokinetic-pharmacodynamic (PK/PD) model of a direct thrombin inhibitor, argatroban to predict the concentration-effect profiles in rats. Argatroban was i.v. injected to rats at 0. 2, 0.8 and 3.2 mg/kg doses (n = 4-5 per dose), and plasma drug levels were determined by a validated LC/MS/MS assay. The pharmacokinetics of argatroban was linear over the i.v. dose range studied. The thrombin time (TT) and the activated partial thromboplastin time (aPTT) were measured in rat plasma and they were found to linearly increase with increasing the dose. A 2-compartment pharmacokinetic model linked with an indirect response pharmacodynamic model was successfully utilized to evaluate the drug concentration-response relationship.

• Journal of KIISE
• /
• v.43 no.8
• /
• pp.878-882
• /
• 2016

Automatic generation of captions for an image is a very difficult task, due to the necessity of computer vision and natural language processing technologies. However, this task has many important applications, such as early childhood education, image retrieval, and navigation for blind. In this paper, we describe a Recurrent Neural Network (RNN) model for generating image captions, which takes image features extracted from a Convolutional Neural Network (CNN). We demonstrate that our models produce state of the art results in image caption generation experiments on the Flickr 8K, Flickr 30K, and MS COCO datasets.

• Journal of Korean Society for Atmospheric Environment
• /
• v.19 no.2
• /
• pp.157-165
• /
• 2003

A combined process of non-thermal plasma and catalytic technique has been investigated to treat $CH_3$CN gas in the atmosphere. A planar type dielectric barrier discharge (DBD) reactor has been used to generate the non-thermal plasma that produces various chemically active species, such as O, N, OH, $O_3$, ion, electrons, etc. Several different types of the beads. which are Molecular Sieve (MS) 5A, MS 13X, Pt/alumina beads, are packed into the DBD reactor, and have been tested to characterize the effects of adsorption and catalytic process on treating the $CH_3$CN gas in the DBD reactor. The test results showed that the operating power consumption and the amounts of the by-products of the non-thermal plasma process can be reduced by the assistance of the adsorption and catalytic process.